[Hub]/) : Traits : Standing height :

chr8:119,737,284-122,078,334

Best TWAS P=9.58e-25 · Best GWAS P=2.8e-27 conditioned to 6.59e-211

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NOV 0.06 0.02 enet 8 0.05 1.5e-06 -5.7 -8.0 1.4e-15 0.76 0.02 0.98 FALSE
2 CommonMind Brain Pre-frontal Cortex TAF2 0.16 0.10 lasso 14 0.15 9.2e-18 -3.5 -5.2 1.9e-07 -0.06 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous TAF2 0.11 0.07 lasso 6 0.10 1.7e-08 5.4 -6.6 5.1e-11 -0.02 0.94 0.00 FALSE
4 GTEx Adrenal Gland DEPTOR 0.16 -0.01 enet 24 0.00 3.7e-01 -5.0 8.5 1.9e-17 -0.09 0.10 0.05 TRUE
5 GTEx Artery Aorta NOV 0.12 0.05 enet 18 0.04 3.7e-03 -7.8 -9.9 5.4e-23 0.68 0.10 0.57 FALSE
6 GTEx Artery Tibial NOV 0.09 0.00 enet 33 0.00 2.7e-01 -10.2 -6.8 1.3e-11 0.50 0.04 0.89 FALSE
7 GTEx Brain Cerebellar Hemisphere DEPTOR 0.32 0.15 lasso 8 0.29 3.4e-08 8.0 -8.0 1.6e-15 0.12 0.61 0.02 FALSE
8 GTEx Brain Cerebellum DSCC1 0.71 0.47 lasso 15 0.49 1.7e-16 4.2 -5.1 2.8e-07 0.13 1.00 0.00 TRUE
9 GTEx Brain Cerebellum DEPTOR 0.24 0.22 lasso 3 0.17 7.9e-06 8.0 -8.1 8.0e-16 0.08 0.42 0.05 FALSE
10 GTEx Brain Cortex DSCC1 0.31 0.27 lasso 3 0.28 2.8e-08 4.2 -5.3 9.8e-08 0.12 0.66 0.03 FALSE
11 GTEx Breast Mammary Tissue TAF2 0.09 0.11 lasso 3 0.07 1.2e-04 6.2 -6.3 2.7e-10 0.02 0.50 0.02 FALSE
12 GTEx Cells Transformed fibroblasts NOV 0.10 0.04 enet 30 0.03 3.7e-03 -10.8 -9.3 1.5e-20 0.77 0.00 0.99 FALSE
13 GTEx Colon Sigmoid NOV 0.15 0.16 lasso 4 0.15 6.6e-06 -10.2 -10.2 2.4e-24 0.87 0.07 0.91 FALSE
14 GTEx Colon Sigmoid DEPTOR 0.28 0.22 lasso 4 0.23 1.7e-08 7.0 7.2 8.1e-13 -0.08 0.92 0.00 FALSE
15 GTEx Colon Sigmoid RP11-760H22.2 0.23 0.05 enet 39 0.09 4.1e-04 7.0 5.6 2.2e-08 -0.07 0.11 0.05 FALSE
16 GTEx Esophagus Gastroesophageal Junction TAF2 0.14 0.00 enet 12 -0.01 5.6e-01 6.2 -7.4 1.2e-13 0.12 0.11 0.05 TRUE
17 GTEx Esophagus Muscularis TAF2 0.13 0.09 lasso 4 0.08 1.5e-05 5.4 -5.4 5.9e-08 0.04 0.63 0.02 FALSE
18 GTEx Esophagus Muscularis NOV 0.11 0.03 enet 19 0.05 3.9e-04 -10.2 -7.3 2.4e-13 0.71 0.04 0.92 FALSE
19 GTEx Liver RP11-760H22.2 0.14 0.08 lasso 2 0.10 1.3e-03 4.9 -6.3 3.8e-10 0.02 0.32 0.05 TRUE
20 GTEx Lung TAF2 0.14 0.09 lasso 4 0.07 5.5e-06 5.8 -6.3 2.3e-10 0.04 0.88 0.01 FALSE
21 GTEx Lung NOV 0.06 0.02 enet 23 0.03 2.5e-03 -6.8 -10.3 9.6e-25 0.67 0.28 0.24 TRUE
22 GTEx Lung DEPTOR 0.16 0.12 enet 28 0.15 1.3e-11 8.0 7.3 2.5e-13 -0.12 1.00 0.00 FALSE
23 GTEx Nerve Tibial TAF2 0.14 0.04 enet 10 0.07 1.5e-05 5.8 -8.0 1.1e-15 0.25 0.83 0.10 TRUE
24 GTEx Prostate DSCC1 0.52 0.46 lasso 5 0.48 6.2e-14 4.2 -6.0 1.8e-09 0.18 0.97 0.00 FALSE
25 GTEx Skin Sun Exposed Lower leg NOV 0.11 0.03 lasso 7 0.04 1.4e-04 -9.7 -9.0 2.3e-19 0.83 0.07 0.92 FALSE
26 GTEx Thyroid COL14A1 0.10 0.02 enet 14 0.02 2.3e-02 6.3 -7.2 5.3e-13 0.18 0.19 0.05 FALSE
27 GTEx Whole Blood TAF2 0.05 0.03 enet 11 0.05 4.9e-05 5.4 -5.2 2.5e-07 0.00 0.63 0.01 TRUE
28 NTR Blood NOV 0.02 0.01 bslmm 481 0.01 1.7e-04 -10.5 -9.5 2.7e-21 0.68 0.09 0.89 TRUE
29 ROSMAP Brain Pre-frontal Cortex NOV 0.10 0.02 bslmm 475 0.07 5.7e-09 -9.7 6.1 1.4e-09 -0.61 0.25 0.74 FALSE
30 YFS Blood TAF2 0.02 0.02 lasso 8 0.02 5.8e-06 5.4 -5.3 9.9e-08 0.04 0.99 0.00 FALSE
31 The Cancer Genome Atlas Bladder Urothelial Carcinoma NOV 0.03 0.00 blup 42 0.01 5.3e-02 -9.7 -9.9 6.1e-23 0.85 0.05 0.40 FALSE
32 The Cancer Genome Atlas Colon Adenocarcinoma NOV 0.31 0.10 blup 42 0.10 1.2e-06 -10.2 -8.4 3.4e-17 0.69 0.12 0.81 FALSE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NOV 0.06 0.00 blup 42 0.03 4.3e-04 -10.5 -5.8 6.1e-09 0.52 0.02 0.38 FALSE
34 The Cancer Genome Atlas Pancreatic Adenocarcinoma NOV 0.11 0.02 enet 15 0.05 2.9e-03 -10.2 -9.1 5.8e-20 0.74 0.02 0.35 FALSE
35 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma DSCC1 0.10 0.04 blup 54 0.06 2.2e-03 5.0 -6.4 1.3e-10 0.14 0.03 0.64 FALSE
36 The Cancer Genome Atlas Prostate Adenocarcinoma NOV 0.04 0.05 blup 42 0.05 8.7e-06 -10.5 -9.4 7.7e-21 0.85 0.01 0.99 FALSE
37 The Cancer Genome Atlas Testicular Germ Cell Tumors DEPDC6 0.19 0.04 blup 142 0.11 1.1e-04 4.9 -6.8 1.1e-11 0.17 0.03 0.95 FALSE