Best TWAS P=5.44e-13 · Best GWAS P=4.04e-32 conditioned to 1.09e-26
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | NUDT5 | 0.13 | 0.07 | enet | 14 | 0.07 | 3.3e-06 | -4.7 | -5.1 | 2.8e-07 | -0.01 | 0.93 | 0.00 | FALSE |
| 2 | GTEx | Whole Blood | PROSER2 | 0.11 | 0.07 | enet | 12 | 0.07 | 2.5e-07 | 7.5 | 7.2 | 5.4e-13 | 0.07 | 0.01 | 0.99 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CCDC3 | 0.15 | 0.03 | enet | 34 | 0.12 | 1.5e-15 | 3.1 | 6.2 | 5.0e-10 | -0.45 | 0.43 | 0.57 | TRUE |
| 4 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | NUDT5 | 0.13 | -0.01 | blup | 55 | 0.01 | 1.1e-01 | -3.3 | -5.3 | 9.9e-08 | 0.00 | 0.00 | 0.30 | TRUE |