Best TWAS P=3.6e-09 · Best GWAS P=4.08e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Pituitary | PDE2A | 0.25 | 0.19 | lasso | 5 | 0.17 | 4.1e-05 | 5.9 | 5.8 | 5.3e-09 | 1.00 | 0 | 0.97 | FALSE |
| 2 | GTEx | Pituitary | RP11-169D4.2 | 0.19 | 0.20 | lasso | 2 | 0.16 | 7.3e-05 | 5.9 | 5.9 | 3.6e-09 | 0.99 | 0 | 0.96 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PDE2A | 0.02 | 0.02 | lasso | 2 | 0.02 | 2.0e-04 | 5.9 | -5.9 | 4.2e-09 | -1.00 | 0 | 0.99 | FALSE |