[Hub]/) : Traits : Standing height :

chr11:73,767,497-75,612,878

Best TWAS P=6.25e-15 · Best GWAS P=5.01e-49 conditioned to 6.8e-278

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NEU3 0.05 0.04 lasso 3 0.04 3.6e-05 -5.7 6.7 2.8e-11 0.06 0.07 0.88 TRUE
2 CommonMind Brain Pre-frontal Cortex RNF169 0.07 0.04 bslmm 495 0.03 1.1e-04 6.3 6.8 1.2e-11 0.11 0.14 0.84 FALSE
3 CommonMind Brain Pre-frontal Cortex XRRA1 0.59 0.79 lasso 3 0.78 5.8e-152 7.0 7.1 1.1e-12 0.05 0.06 0.94 FALSE
4 GTEx Adipose Subcutaneous XRRA1 0.49 0.62 enet 27 0.64 6.1e-67 7.2 6.9 4.9e-12 0.04 0.05 0.95 FALSE
5 GTEx Adipose Subcutaneous RP11-147I3.1 0.18 0.14 lasso 7 0.17 1.0e-13 6.5 -6.2 5.4e-10 -0.02 0.16 0.84 FALSE
6 GTEx Adipose Visceral Omentum XRRA1 0.51 0.54 lasso 7 0.55 3.8e-33 7.2 7.0 3.0e-12 0.04 0.07 0.93 FALSE
7 GTEx Adrenal Gland XRRA1 0.63 0.69 enet 25 0.69 3.9e-33 7.0 6.5 1.1e-10 0.05 0.07 0.93 FALSE
8 GTEx Adrenal Gland RP11-147I3.1 0.31 0.24 enet 24 0.28 1.6e-10 7.0 -6.0 2.7e-09 -0.02 0.08 0.92 FALSE
9 GTEx Artery Aorta XRRA1 0.57 0.65 lasso 7 0.68 1.1e-50 7.0 7.0 2.4e-12 0.04 0.07 0.93 FALSE
10 GTEx Artery Coronary XRRA1 0.72 0.71 enet 24 0.73 4.8e-35 7.0 6.8 9.2e-12 0.04 0.09 0.91 FALSE
11 GTEx Artery Tibial XRRA1 0.63 0.72 lasso 10 0.74 1.9e-83 7.0 7.0 2.1e-12 0.04 0.06 0.94 FALSE
12 GTEx Brain Caudate basal ganglia XRRA1 0.72 0.61 lasso 5 0.60 2.6e-21 7.1 6.9 4.4e-12 0.04 0.07 0.93 FALSE
13 GTEx Brain Cerebellar Hemisphere XRRA1 0.79 0.74 lasso 8 0.74 2.5e-27 7.0 7.0 2.1e-12 0.04 0.06 0.94 FALSE
14 GTEx Brain Cerebellar Hemisphere RP11-147I3.1 0.36 0.12 lasso 7 0.13 2.6e-04 7.0 -7.0 2.8e-12 -0.04 0.09 0.87 FALSE
15 GTEx Brain Cerebellum XRRA1 0.67 0.65 lasso 9 0.69 2.7e-27 7.1 7.2 9.0e-13 0.04 0.06 0.94 FALSE
16 GTEx Brain Hippocampus XRRA1 0.57 0.48 lasso 6 0.49 2.3e-13 7.1 6.9 4.2e-12 0.04 0.08 0.92 FALSE
17 GTEx Brain Hypothalamus XRRA1 0.51 0.44 enet 13 0.44 1.4e-11 7.2 6.4 1.7e-10 0.04 0.09 0.91 FALSE
18 GTEx Brain Hypothalamus RP11-147I3.1 0.25 0.19 enet 19 0.20 1.9e-05 7.1 -5.8 5.2e-09 -0.02 0.10 0.75 FALSE
19 GTEx Brain Nucleus accumbens basal ganglia XRRA1 0.70 0.50 lasso 8 0.51 1.0e-15 7.1 7.3 2.6e-13 0.03 0.07 0.93 FALSE
20 GTEx Brain Nucleus accumbens basal ganglia RP11-147I3.1 0.23 0.20 lasso 1 0.17 2.9e-05 7.0 -7.0 1.9e-12 -0.04 0.08 0.76 FALSE
21 GTEx Brain Putamen basal ganglia XRRA1 0.55 0.50 lasso 3 0.50 9.3e-14 7.1 7.1 1.0e-12 0.05 0.07 0.93 FALSE
22 GTEx Brain Putamen basal ganglia RP11-147I3.1 0.19 0.20 lasso 2 0.20 2.0e-05 7.1 -7.1 1.1e-12 -0.05 0.08 0.83 FALSE
23 GTEx Breast Mammary Tissue XRRA1 0.48 0.57 lasso 1 0.57 8.3e-35 7.0 7.0 2.0e-12 0.04 0.07 0.93 FALSE
24 GTEx Breast Mammary Tissue (Male) XRRA1 0.49 0.32 lasso 4 0.29 1.6e-07 7.0 6.7 2.6e-11 0.04 0.07 0.92 FALSE
25 GTEx Cells EBV-transformed lymphocytes XRRA1 0.64 0.72 lasso 4 0.71 6.1e-32 7.2 7.2 7.5e-13 0.04 0.06 0.94 FALSE
26 GTEx Cells Transformed fibroblasts RP11-147I3.1 0.13 0.14 lasso 6 0.14 1.1e-10 7.2 -5.5 3.2e-08 -0.03 0.06 0.94 FALSE
27 GTEx Colon Transverse XRRA1 0.64 0.66 lasso 7 0.68 6.8e-43 6.6 6.9 5.4e-12 0.04 0.08 0.92 FALSE
28 GTEx Colon Transverse RP11-147I3.1 0.26 0.27 enet 14 0.29 2.8e-14 7.2 -6.3 3.7e-10 -0.03 0.06 0.94 FALSE
29 GTEx Esophagus Gastroesophageal Junction XRRA1 0.55 0.68 enet 17 0.68 5.2e-33 7.0 6.9 4.8e-12 0.04 0.07 0.93 FALSE
30 GTEx Esophagus Mucosa XRRA1 0.64 0.76 lasso 7 0.76 5.9e-75 7.0 7.1 1.6e-12 0.04 0.06 0.94 FALSE
31 GTEx Esophagus Mucosa RP11-147I3.1 0.20 0.12 lasso 4 0.12 1.2e-08 7.0 -7.0 3.0e-12 -0.04 0.08 0.92 FALSE
32 GTEx Esophagus Muscularis XRRA1 0.59 0.70 lasso 5 0.70 1.2e-58 7.2 7.1 9.5e-13 0.04 0.06 0.94 FALSE
33 GTEx Esophagus Muscularis RP11-147I3.1 0.08 0.03 lasso 5 0.04 2.6e-03 6.4 -6.7 1.7e-11 -0.03 0.14 0.79 FALSE
34 GTEx Heart Atrial Appendage RP11-147I3.1 0.14 0.11 lasso 3 0.10 3.8e-05 6.5 -6.7 2.9e-11 -0.03 0.09 0.90 FALSE
35 GTEx Heart Left Ventricle XRRA1 0.58 0.69 lasso 6 0.69 1.0e-49 7.0 7.1 1.5e-12 0.04 0.06 0.94 FALSE
36 GTEx Heart Left Ventricle RP11-147I3.1 0.21 0.14 lasso 3 0.14 4.6e-08 6.5 -6.8 9.3e-12 -0.03 0.08 0.92 FALSE
37 GTEx Liver XRRA1 0.73 0.63 lasso 7 0.65 1.5e-23 7.0 6.5 9.3e-11 0.03 0.07 0.93 FALSE
38 GTEx Liver RP11-147I3.1 0.35 0.34 lasso 5 0.33 6.0e-10 7.2 -6.3 3.7e-10 -0.02 0.07 0.93 FALSE
39 GTEx Lung XRRA1 0.66 0.70 enet 35 0.72 1.1e-78 7.0 7.2 6.5e-13 0.04 0.06 0.94 FALSE
40 GTEx Muscle Skeletal XRRA1 0.53 0.68 enet 16 0.72 8.9e-100 7.0 7.1 1.6e-12 0.03 0.06 0.94 FALSE
41 GTEx Muscle Skeletal RP11-147I3.1 0.16 0.18 lasso 7 0.17 3.5e-16 7.0 -6.8 1.3e-11 -0.03 0.07 0.93 FALSE
42 GTEx Nerve Tibial XRRA1 0.52 0.67 lasso 5 0.68 3.6e-64 7.2 7.1 1.6e-12 0.04 0.05 0.95 FALSE
43 GTEx Ovary XRRA1 0.69 0.56 enet 18 0.65 1.7e-20 7.0 6.5 1.0e-10 0.04 0.09 0.91 FALSE
44 GTEx Ovary RP11-147I3.1 0.22 0.20 lasso 3 0.22 5.3e-06 7.0 -6.2 5.2e-10 -0.03 0.14 0.83 FALSE
45 GTEx Pancreas XRRA1 0.56 0.64 lasso 5 0.64 1.4e-34 7.2 7.3 3.4e-13 0.04 0.06 0.94 FALSE
46 GTEx Pancreas RP11-147I3.1 0.28 0.18 lasso 7 0.20 1.2e-08 7.2 -7.6 3.4e-14 -0.04 0.08 0.92 FALSE
47 GTEx Pituitary XRRA1 0.67 0.68 lasso 3 0.68 6.4e-23 7.0 7.1 1.4e-12 0.04 0.06 0.94 FALSE
48 GTEx Pituitary RP11-147I3.1 0.40 0.37 enet 19 0.39 8.9e-11 7.2 -6.6 3.6e-11 -0.02 0.07 0.93 FALSE
49 GTEx Prostate XRRA1 0.80 0.63 lasso 12 0.69 1.5e-23 7.1 7.0 1.8e-12 0.03 0.07 0.93 FALSE
50 GTEx Prostate RP11-147I3.1 0.32 0.29 lasso 10 0.24 9.0e-07 6.4 -5.8 5.9e-09 -0.01 0.09 0.90 FALSE
51 GTEx Skin Not Sun Exposed Suprapubic XRRA1 0.51 0.59 enet 12 0.60 5.3e-41 7.0 7.1 1.4e-12 0.04 0.06 0.94 FALSE
52 GTEx Skin Sun Exposed Lower leg XRRA1 0.50 0.65 lasso 6 0.66 7.4e-72 7.0 7.0 2.3e-12 0.04 0.08 0.92 FALSE
53 GTEx Small Intestine Terminal Ileum RP11-147I3.1 0.32 0.08 lasso 6 0.06 2.1e-02 7.0 -7.0 2.0e-12 -0.04 0.12 0.54 FALSE
54 GTEx Spleen XRRA1 0.67 0.63 lasso 8 0.68 5.8e-23 7.0 6.5 1.0e-10 0.03 0.08 0.92 FALSE
55 GTEx Stomach XRRA1 0.57 0.64 lasso 6 0.66 7.9e-41 7.1 7.1 9.8e-13 0.03 0.06 0.94 FALSE
56 GTEx Testis SLCO2B1 0.28 0.11 lasso 7 0.15 2.9e-07 4.4 -5.9 4.0e-09 0.03 0.76 0.01 FALSE
57 GTEx Thyroid XRRA1 0.66 0.76 lasso 4 0.76 1.1e-88 7.0 7.1 1.5e-12 0.05 0.07 0.93 FALSE
58 GTEx Thyroid RP11-147I3.1 0.34 0.35 lasso 8 0.37 1.9e-29 7.2 -6.5 1.0e-10 -0.03 0.05 0.95 FALSE
59 GTEx Uterus XRRA1 0.59 0.59 lasso 7 0.59 6.9e-15 7.2 7.1 1.6e-12 0.04 0.08 0.92 FALSE
60 GTEx Uterus RP11-147I3.1 0.29 0.06 lasso 4 0.09 6.2e-03 6.5 -5.3 1.5e-07 -0.01 0.11 0.44 FALSE
61 GTEx Vagina XRRA1 0.72 0.75 lasso 4 0.76 2.5e-25 7.2 6.8 1.0e-11 0.04 0.06 0.94 FALSE
62 GTEx Whole Blood XRRA1 0.44 0.56 enet 13 0.55 4.0e-60 7.0 6.8 9.1e-12 0.04 0.07 0.93 FALSE
63 METSIM Adipose XRRA1 0.31 0.40 lasso 13 0.40 3.6e-65 7.1 6.7 3.0e-11 0.03 0.06 0.94 FALSE
64 NTR Blood XRRA1 0.09 0.16 lasso 3 0.16 3.2e-49 7.2 7.1 1.2e-12 0.04 0.05 0.95 FALSE
65 ROSMAP Brain Pre-frontal Cortex XRRA1 0.56 0.72 bslmm 505 0.72 6.2e-136 7.2 7.2 4.4e-13 0.04 0.06 0.94 FALSE
66 ROSMAP Brain Pre-frontal Cortex RP11-147I3.1 0.28 0.41 lasso 4 0.41 6.9e-57 7.1 -7.0 2.3e-12 -0.04 0.06 0.94 FALSE
67 YFS Blood XRRA1 0.14 0.18 lasso 6 0.18 5.1e-58 7.0 6.7 2.2e-11 0.04 0.06 0.94 FALSE
68 The Cancer Genome Atlas Bladder Urothelial Carcinoma XRRA1 0.34 0.39 enet 10 0.39 5.6e-35 7.0 7.0 2.9e-12 0.04 0.10 0.90 FALSE
69 The Cancer Genome Atlas Breast Invasive Carcinoma POLD3 0.02 0.01 lasso 3 0.01 1.8e-03 5.7 -6.4 1.7e-10 0.00 0.04 0.57 TRUE
70 The Cancer Genome Atlas Breast Invasive Carcinoma XRRA1 0.29 0.43 lasso 4 0.43 2.7e-97 7.0 7.0 1.8e-12 0.04 0.08 0.92 FALSE
71 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma XRRA1 0.34 0.30 lasso 3 0.29 1.0e-14 7.2 7.2 6.1e-13 0.05 0.05 0.95 FALSE
72 The Cancer Genome Atlas Colon Adenocarcinoma XRRA1 0.54 0.55 lasso 3 0.57 8.9e-40 7.0 6.8 1.1e-11 0.04 0.06 0.94 FALSE
73 The Cancer Genome Atlas Esophageal Carcinoma XRRA1 0.43 0.39 lasso 5 0.36 2.8e-12 7.0 6.6 4.0e-11 0.03 0.06 0.94 FALSE
74 The Cancer Genome Atlas Glioblastoma Multiforme XRRA1 0.63 0.58 lasso 4 0.58 2.7e-21 6.6 6.9 6.7e-12 0.05 0.06 0.94 FALSE
75 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma XRRA1 0.28 0.38 lasso 4 0.38 1.3e-44 7.0 7.0 2.3e-12 0.04 0.06 0.94 FALSE
76 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma XRRA1 0.52 0.69 lasso 6 0.70 2.8e-111 7.1 6.9 5.0e-12 0.04 0.05 0.95 FALSE
77 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma XRRA1 0.40 0.54 lasso 7 0.54 1.2e-35 7.2 7.2 8.3e-13 0.04 0.05 0.95 FALSE
78 The Cancer Genome Atlas Brain Lower Grade Glioma XRRA1 0.53 0.64 enet 34 0.65 1.2e-97 7.0 7.0 1.8e-12 0.05 0.08 0.92 FALSE
79 The Cancer Genome Atlas Liver Hepatocellular Carcinoma XRRA1 0.37 0.36 blup 73 0.36 5.7e-18 7.0 7.8 6.3e-15 0.05 0.06 0.94 TRUE
80 The Cancer Genome Atlas Lung Adenocarcinoma SPCS2 0.04 0.03 lasso 2 0.02 1.3e-03 -7.2 6.1 1.4e-09 0.08 0.00 0.97 TRUE
81 The Cancer Genome Atlas Lung Adenocarcinoma XRRA1 0.39 0.54 lasso 4 0.53 5.7e-73 7.0 7.1 1.4e-12 0.04 0.08 0.92 FALSE
82 The Cancer Genome Atlas Lung Squamous Cell Carcinoma XRRA1 0.29 0.43 lasso 2 0.43 9.7e-54 7.0 6.9 3.9e-12 0.04 0.09 0.91 FALSE
83 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma XRRA1 0.45 0.53 lasso 3 0.53 4.2e-42 7.1 7.1 1.3e-12 0.05 0.05 0.95 FALSE
84 The Cancer Genome Atlas Pancreatic Adenocarcinoma XRRA1 0.45 0.58 enet 15 0.61 2.4e-31 7.2 6.6 3.5e-11 0.04 0.05 0.95 TRUE
85 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma XRRA1 0.53 0.35 enet 6 0.39 9.9e-17 7.0 6.8 9.1e-12 0.04 0.10 0.90 FALSE
86 The Cancer Genome Atlas Prostate Adenocarcinoma XRRA1 0.50 0.64 enet 12 0.65 2.8e-90 7.2 6.8 1.5e-11 0.03 0.05 0.95 FALSE
87 The Cancer Genome Atlas Rectum Adenocarcinoma XRRA1 0.65 0.69 lasso 3 0.69 1.6e-21 7.1 7.1 1.2e-12 0.04 0.05 0.95 FALSE
88 The Cancer Genome Atlas Soft Tissue Sarcoma XRRA1 0.27 0.34 lasso 4 0.34 7.5e-21 7.0 6.9 5.1e-12 0.04 0.05 0.95 FALSE
89 The Cancer Genome Atlas Skin Cutaneous Melanoma XRRA1 0.37 0.40 lasso 8 0.37 5.7e-11 7.0 7.1 1.6e-12 0.04 0.06 0.94 FALSE
90 The Cancer Genome Atlas Stomach Adenocarcinoma XRRA1 0.49 0.58 lasso 9 0.57 6.3e-50 7.0 6.9 5.3e-12 0.04 0.06 0.94 FALSE
91 The Cancer Genome Atlas Testicular Germ Cell Tumors XRRA1 0.43 0.32 lasso 6 0.31 1.9e-11 7.1 6.9 4.1e-12 0.04 0.06 0.94 FALSE
92 The Cancer Genome Atlas Thyroid Carcinoma POLD3 0.03 0.00 blup 77 0.01 1.3e-02 5.6 -6.2 7.4e-10 0.03 0.01 0.77 FALSE
93 The Cancer Genome Atlas Thyroid Carcinoma XRRA1 0.59 0.69 lasso 6 0.70 5.4e-96 7.0 6.8 1.4e-11 0.04 0.07 0.93 FALSE
94 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma XRRA1 0.41 0.32 lasso 8 0.30 3.4e-09 7.0 7.0 2.8e-12 0.05 0.06 0.94 FALSE