[Hub]/) : Traits : Standing height : ← →

chr12:69,045,442-70,671,423

Best TWAS P=2.13e-38 · Best GWAS P=2.61e-48 conditioned to 0.00142

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous YEATS4 0.32 0.28 enet 17 0.30 1.0e-24 4.9 -5.4 6.2e-08 -0.06 1.00 0.00 FALSE
2 GTEx Brain Cortex YEATS4 0.22 0.11 enet 18 0.09 1.8e-03 4.9 -5.6 2.5e-08 -0.08 0.36 0.05 FALSE
3 GTEx Brain Hypothalamus YEATS4 0.21 0.00 enet 21 0.03 6.1e-02 -4.7 -6.9 4.2e-12 -0.23 0.08 0.06 TRUE
4 GTEx Brain Nucleus accumbens basal ganglia YEATS4 0.29 0.25 enet 8 0.17 2.6e-05 4.9 -5.5 4.9e-08 -0.07 0.42 0.03 FALSE
5 GTEx Heart Atrial Appendage LYZ 0.20 0.20 enet 17 0.16 1.7e-07 4.6 -5.2 1.9e-07 -0.11 0.98 0.00 FALSE
6 GTEx Skin Sun Exposed Lower leg LYZ 0.09 0.10 enet 13 0.10 8.0e-09 4.9 -5.9 3.9e-09 -0.17 1.00 0.00 FALSE
7 GTEx Spleen RP11-1143G9.4 0.29 0.09 lasso 11 0.09 2.9e-03 4.3 -5.3 1.1e-07 -0.15 0.32 0.04 FALSE
8 GTEx Stomach YEATS4 0.19 0.16 lasso 8 0.12 2.7e-06 4.9 -5.3 9.1e-08 -0.02 0.85 0.02 FALSE
9 GTEx Thyroid FRS2 0.30 0.16 lasso 6 0.17 8.8e-13 14.6 13.0 2.1e-38 0.93 0.00 1.00 TRUE
10 The Cancer Genome Atlas Lung Adenocarcinoma YEATS4 0.03 0.00 blup 73 0.01 7.3e-03 -2.5 -5.2 1.5e-07 0.03 0.04 0.03 FALSE
11 The Cancer Genome Atlas Pancreatic Adenocarcinoma YEATS4 0.19 0.04 enet 15 0.08 4.2e-04 4.9 -5.3 9.4e-08 -0.01 0.22 0.04 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma LYZ 0.06 0.02 blup 43 0.03 7.4e-03 -3.8 -5.2 1.7e-07 -0.07 0.01 0.61 FALSE