Hub : Genes

YEATS4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3700 0.0410 0.0e+00 0.230 0.337 0.444 0.379 0.453 1.6e-27 2.3e-42 1.8e-59 1.1e-48 4.6e-61
2 GTEx Adipose Subcutaneous 0.3220 0.0480 0.0e+00 0.276 NA 0.298 NA 0.283 1.1e-22 NA 1.0e-24 NA 2.5e-23
3 GTEx Adipose Visceral Omentum 0.3180 0.0660 2.1e-08 0.305 NA 0.267 NA 0.287 2.6e-16 NA 3.5e-14 NA 2.7e-15
4 GTEx Adrenal Gland 0.4512 0.0877 1.9e-06 0.246 NA 0.301 NA 0.219 2.4e-09 NA 2.1e-11 NA 2.2e-08
5 GTEx Artery Aorta 0.2490 0.0670 9.1e-05 0.117 NA 0.214 NA 0.197 5.6e-07 NA 5.0e-12 NA 4.3e-11
6 GTEx Artery Coronary 0.3420 0.0850 7.5e-05 0.103 NA 0.085 NA 0.121 2.5e-04 NA 8.3e-04 NA 7.0e-05
7 GTEx Artery Tibial 0.3733 0.0548 1.4e-15 0.232 NA 0.348 NA 0.342 4.1e-18 NA 3.2e-28 NA 1.2e-27
8 GTEx Brain Cerebellum 0.3530 0.1040 1.3e-04 0.155 NA 0.199 NA 0.159 2.5e-05 NA 1.5e-06 NA 1.9e-05
9 GTEx Brain Cortex 0.2230 0.0820 3.7e-03 0.113 NA 0.090 NA 0.030 5.2e-04 NA 1.8e-03 NA 5.2e-02
10 GTEx Brain Frontal Cortex BA9 0.2751 0.0883 3.4e-03 0.000 NA 0.032 NA 0.079 3.3e-01 NA 4.8e-02 NA 4.1e-03
11 GTEx Brain Hypothalamus 0.2090 0.0860 8.0e-03 -0.004 NA 0.032 NA 0.028 4.0e-01 NA 6.1e-02 NA 7.3e-02
12 GTEx Brain Nucleus accumbens basal ganglia 0.2910 0.1020 1.6e-03 0.250 NA 0.170 NA 0.112 2.3e-07 NA 2.6e-05 NA 6.6e-04
13 GTEx Breast Mammary Tissue 0.4420 0.0740 3.3e-09 0.298 NA 0.252 NA 0.290 9.1e-16 NA 3.0e-13 NA 2.8e-15
14 GTEx Breast Mammary Tissue (Male) 0.2508 0.1077 3.0e-02 0.199 NA 0.045 NA 0.131 2.2e-05 NA 3.4e-02 NA 6.1e-04
15 GTEx Breast Mammary Tissue (Female) 0.2800 0.0941 2.3e-03 0.258 NA 0.192 NA 0.168 2.6e-08 NA 2.2e-06 NA 1.0e-05
16 GTEx Cells EBV-transformed lymphocytes 0.4680 0.0980 6.8e-07 0.432 NA 0.429 NA 0.431 1.6e-15 NA 2.1e-15 NA 1.8e-15
17 GTEx Cells Transformed fibroblasts 0.1440 0.0440 8.8e-04 0.105 NA 0.111 NA 0.112 3.0e-08 NA 1.2e-08 NA 9.7e-09
18 GTEx Colon Sigmoid 0.1950 0.0620 5.6e-04 0.257 NA 0.231 NA 0.251 1.3e-09 NA 1.1e-08 NA 2.2e-09
19 GTEx Colon Transverse 0.1660 0.0610 2.7e-03 0.059 NA 0.104 NA 0.072 8.6e-04 NA 1.2e-05 NA 2.5e-04
20 GTEx Esophagus Mucosa 0.2610 0.0600 1.3e-07 0.145 NA 0.100 NA 0.120 6.1e-10 NA 3.2e-07 NA 2.2e-08
21 GTEx Esophagus Muscularis 0.3990 0.0610 5.1e-12 0.228 NA 0.337 NA 0.335 5.8e-14 NA 3.7e-21 NA 5.0e-21
22 GTEx Heart Atrial Appendage 0.2790 0.0740 3.8e-05 0.192 NA 0.176 NA 0.195 5.3e-09 NA 2.5e-08 NA 3.7e-09
23 GTEx Heart Left Ventricle 0.2120 0.0542 1.8e-05 0.175 NA 0.110 NA 0.086 1.2e-09 NA 1.8e-06 NA 2.5e-05
24 GTEx Lung 0.1309 0.0329 4.2e-07 0.175 NA 0.146 NA 0.165 2.1e-13 NA 2.9e-11 NA 1.1e-12
25 GTEx Muscle Skeletal 0.2359 0.0397 5.6e-17 0.250 NA 0.242 NA 0.244 2.0e-24 NA 1.6e-23 NA 8.3e-24
26 GTEx Nerve Tibial 0.3247 0.0554 1.6e-11 0.218 NA 0.322 NA 0.317 1.8e-15 NA 2.6e-23 NA 5.7e-23
27 GTEx Ovary 0.2780 0.0920 3.4e-03 0.207 NA 0.081 NA 0.139 8.0e-06 NA 5.0e-03 NA 2.9e-04
28 GTEx Pituitary 0.2880 0.0890 1.4e-03 0.050 NA 0.047 NA 0.078 2.1e-02 NA 2.6e-02 NA 5.2e-03
29 GTEx Prostate 0.4010 0.1070 7.8e-04 0.007 NA 0.008 NA 0.056 2.1e-01 NA 1.9e-01 NA 1.6e-02
30 GTEx Skin Not Sun Exposed Suprapubic 0.3620 0.0550 7.3e-14 0.368 NA 0.351 NA 0.367 3.6e-21 NA 4.2e-20 NA 3.9e-21
31 GTEx Skin Sun Exposed Lower leg 0.3020 0.0450 0.0e+00 0.315 NA 0.308 NA 0.305 1.4e-26 NA 6.6e-26 NA 1.3e-25
32 GTEx Stomach 0.1940 0.0570 1.6e-04 0.155 NA 0.112 NA 0.119 6.8e-08 NA 5.4e-06 NA 2.7e-06
33 GTEx Testis 0.5560 0.0610 6.7e-16 0.407 NA 0.602 NA 0.537 2.0e-19 NA 7.1e-33 NA 8.9e-28
34 GTEx Thyroid 0.3210 0.0480 0.0e+00 0.367 NA 0.369 NA 0.371 2.2e-29 NA 1.5e-29 NA 1.0e-29
35 GTEx Uterus 0.3760 0.1220 4.1e-03 0.287 NA 0.109 NA 0.008 1.3e-06 NA 3.2e-03 NA 2.2e-01
36 GTEx Vagina 0.4540 0.1230 1.9e-03 0.128 NA 0.031 NA 0.175 7.7e-04 NA 6.7e-02 NA 8.2e-05
37 METSIM Adipose 0.2409 0.0378 0.0e+00 0.287 0.219 0.262 0.272 0.278 2.6e-43 3.2e-32 3.8e-39 1.2e-40 8.4e-42
38 YFS Blood 0.2836 0.0334 0.0e+00 0.260 0.288 0.318 0.313 0.322 1.3e-84 2.6e-95 2.7e-107 5.6e-105 1.4e-108
39 TCGA Breast Invasive Carcinoma 0.0747 0.0279 3.2e-11 0.059 0.064 0.056 NA 0.056 3.4e-12 4.2e-13 1.4e-11 NA 1.3e-11
40 TCGA Cervical Squamous Cell Carcinoma 0.1060 0.0490 9.5e-04 0.017 0.033 0.027 NA 0.016 4.7e-02 9.0e-03 1.8e-02 NA 5.4e-02
41 TCGA Colon Adenocarcinoma 0.1030 0.0470 1.3e-03 -0.005 0.009 0.005 NA 0.001 9.8e-01 9.1e-02 1.5e-01 NA 2.8e-01
42 TCGA Kidney Renal Clear Cell Carcinoma 0.2640 0.0590 0.0e+00 0.175 0.260 0.291 NA 0.279 2.6e-19 4.2e-29 4.9e-33 NA 1.9e-31
43 TCGA Kidney Renal Papillary Cell Carcinoma 0.1230 0.0410 3.5e-07 0.121 0.117 0.172 NA 0.174 2.1e-07 3.5e-07 4.2e-10 NA 3.5e-10
44 TCGA Brain Lower Grade Glioma 0.2369 0.0572 0.0e+00 0.137 0.195 0.256 NA 0.261 2.5e-15 1.0e-21 6.1e-29 NA 1.8e-29
45 TCGA Liver Hepatocellular Carcinoma 0.1380 0.0600 9.4e-04 -0.006 0.031 0.023 NA 0.003 8.5e-01 1.3e-02 2.9e-02 NA 2.2e-01
46 TCGA Lung Adenocarcinoma 0.0319 0.0164 2.7e-03 -0.002 0.014 0.007 NA 0.001 8.8e-01 7.3e-03 4.7e-02 NA 2.1e-01
47 TCGA Pancreatic Adenocarcinoma 0.1920 0.0740 3.9e-05 0.039 0.029 0.076 NA -0.003 9.8e-03 2.3e-02 4.2e-04 NA 4.5e-01
48 TCGA Pheochromocytoma and Paraganglioma 0.1990 0.0700 3.3e-06 0.209 0.122 0.166 NA 0.186 9.1e-09 1.5e-05 3.9e-07 NA 7.2e-08
49 TCGA Prostate Adenocarcinoma 0.1823 0.0464 0.0e+00 0.151 0.169 0.209 NA 0.211 1.5e-15 2.4e-17 1.8e-21 NA 1.1e-21
50 TCGA Thyroid Carcinoma 0.3880 0.0640 0.0e+00 0.268 0.414 0.467 NA 0.465 4.0e-26 2.5e-43 1.2e-50 NA 2.3e-50

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
Bipolar Disorder (2018) 2.2 3.4 8.0 1.4 2.2 2.3 1.4 0.8 1.1 1.7 1.0 2.5 1.7 0.0 2.0 2.5 2.6 2.8 -2.3 -0.1 2.4 1.7 2.1 1.8 2.2 2.7 2.4 2.3 1.4 2.3 0.1 1.4 2.2 2.6 1.2 0.1 2.2 2.1 2.1 2.3 2.3 0.1 -2.2 -0.5 1.8 1.7 1.5 0.6 1.9 1.5 -0.0 2.1 1.6
Bipolar Disorder or Schizophrenia 1.1 2.7 8.8 1.6 2.3 1.8 1.5 1.7 3.0 2.1 0.8 1.6 1.6 0.0 1.6 1.9 1.7 2.2 -1.4 0.3 1.7 2.2 2.4 1.5 1.6 1.9 1.7 1.8 1.8 1.7 0.3 0.9 1.5 2.0 0.8 -0.8 1.8 2.3 1.6 1.8 2.9 0.4 -0.9 -0.1 2.0 1.4 1.3 1.0 1.7 1.4 0.3 1.7 1.7
Depressed Affect (Nagel 2018) 0.4 0.9 2.8 1.1 1.1 0.7 1.2 1.4 0.8 1.2 0.8 1.2 1.1 -1.2 0.7 1.1 0.4 0.7 -0.4 0.8 0.7 1.0 0.6 1.3 0.9 1.2 0.8 0.7 0.9 0.9 0.8 1.0 0.5 0.8 0.1 -0.3 0.8 1.7 0.6 0.7 0.9 1.1 -0.8 0.5 1.1 1.3 1.1 1.0 1.4 0.8 1.0 1.2 1.1
Depression (Nagel 2018) 0.4 0.6 2.6 -0.8 -1.1 -0.6 -0.9 -0.7 -1.5 -1.4 -1.1 -0.3 -0.5 -1.6 -0.7 -0.7 -0.5 -1.0 0.5 -0.6 -0.6 -0.8 -1.4 -0.4 -0.6 -0.5 -0.6 -0.7 -0.9 -0.6 -0.4 -0.8 -0.8 -0.6 -1.0 0.3 -0.7 -0.3 -1.0 -0.6 -1.4 -0.2 0.1 0.4 -0.8 -0.6 -0.5 -0.2 -0.6 -0.6 -0.4 -0.5 -0.9
Intelligence (Savage-Jansen 2018) 0.4 1.3 3.9 1.2 0.9 0.9 0.7 1.6 1.6 1.2 0.5 0.8 1.4 2.0 1.5 0.7 0.5 0.8 -0.6 1.1 0.9 1.1 0.6 1.1 1.0 0.6 0.9 0.9 1.2 1.1 1.6 1.1 1.1 0.5 1.9 0.0 1.1 1.2 1.2 0.9 0.8 1.2 -0.3 0.9 1.7 1.1 1.2 1.2 1.2 1.4 0.9 1.3 1.3
Neuroticism (Nagel 2018) 0.1 0.3 1.6 0.5 0.1 -0.2 0.8 1.0 0.1 0.3 -0.4 -0.1 0.6 -0.6 0.0 0.1 -0.5 -0.2 0.4 0.8 -0.2 0.3 -0.2 0.7 0.1 -0.2 -0.2 -0.2 0.5 -0.0 0.8 0.7 -0.4 -0.1 -0.7 -1.3 -0.1 0.6 -0.4 -0.2 0.2 1.0 0.1 0.4 0.3 0.5 0.4 0.5 0.5 0.3 0.9 0.5 0.3
Schizophrenia (2018) 0.2 0.4 2.8 0.6 0.9 0.3 0.7 1.1 1.7 0.9 0.2 0.1 0.6 0.0 0.4 0.4 0.2 0.6 0.0 0.5 0.2 1.1 0.9 0.4 0.3 0.3 0.2 0.4 0.9 0.3 0.2 0.1 0.1 0.5 0.0 -1.1 0.4 0.9 0.3 0.3 1.4 0.3 0.5 0.3 0.7 0.4 0.4 0.7 0.6 0.6 0.4 0.5 0.5
Schizophrenia vs Biploar Disorder 0.6 0.8 3.5 -0.7 -0.9 -1.1 -0.5 -0.1 -0.5 -0.8 -1.6 -1.6 -0.5 -0.3 -0.8 -1.2 -1.4 -1.1 1.1 0.1 -1.1 -0.7 -1.0 -0.8 -1.0 -1.6 -1.1 -1.1 -0.4 -1.0 0.3 -0.7 -1.0 -1.1 -0.7 -1.0 -1.0 -0.0 -0.7 -1.1 -0.6 -0.3 1.9 -0.1 -1.0 -0.8 -0.8 -0.5 -1.0 -0.3 0.0 -0.7 -1.0
Worry (Nagel 2018) 0.1 0.1 0.6 0.3 0.0 0.3 0.7 0.6 -0.1 0.1 -0.3 -0.2 0.5 0.2 0.4 0.2 0.0 0.2 -0.3 0.3 0.3 0.1 0.2 0.8 0.3 -0.2 0.2 0.2 0.6 0.3 0.2 0.7 0.1 0.2 -0.6 -0.1 0.3 0.4 0.0 0.3 0.0 0.6 -0.2 -0.4 0.0 0.3 0.3 0.0 0.2 0.5 0.3 0.5 0.2
Alzheimer’s Disease (in mother) 0.6 0.7 1.7 1.0 1.1 0.6 1.0 0.8 1.0 1.3 1.1 1.2 0.9 1.2 0.7 0.6 0.6 0.6 -0.5 0.9 0.6 0.6 0.6 0.8 0.8 1.0 0.7 0.7 0.6 0.7 1.1 0.7 0.5 0.8 0.6 1.1 0.6 0.3 0.9 0.6 0.6 0.8 -0.5 -0.3 0.9 1.1 0.9 1.0 0.3 1.0 0.8 0.9 0.9
Alzheimer’s Disease (in father) 0.1 0.1 0.8 -0.0 -0.4 -0.0 0.2 0.1 -0.4 -0.4 -0.6 -0.3 0.3 -0.9 -0.3 -0.4 -0.2 -0.6 0.1 0.2 0.0 -0.4 -0.1 -0.0 0.0 -0.4 -0.0 -0.0 -0.4 0.1 0.2 0.3 0.0 -0.3 0.0 0.9 -0.0 0.6 0.0 -0.0 -0.7 -0.0 0.8 0.2 -0.4 0.1 0.0 0.2 -0.3 0.7 0.1 0.1 -0.1
Alzheimer’s Disease (including proxy) 0.4 0.6 3.4 0.9 0.8 0.8 1.2 0.6 0.7 0.9 0.3 0.8 1.1 -0.2 0.4 0.6 0.7 0.3 -0.6 0.6 0.8 0.3 0.7 0.7 0.9 0.7 0.9 0.8 0.4 0.9 0.7 1.0 0.8 0.6 0.4 1.9 0.8 0.6 0.8 0.8 0.2 0.5 0.3 0.0 0.6 0.9 0.9 0.6 -0.2 1.2 0.6 0.9 0.8
Crohns Disease (2017) 2.6 5.7 14.5 -2.0 -3.1 -2.6 -2.6 -2.3 -2.6 -2.2 -1.5 -1.9 -2.0 -2.1 -2.7 -2.9 -2.5 -2.9 2.5 -0.5 -2.6 -2.5 -2.4 -2.6 -2.5 -2.2 -2.6 -2.7 -2.6 -2.5 -0.4 -1.5 -2.5 -3.3 -2.0 0.7 -2.7 -3.3 -3.0 -2.6 -3.8 -0.7 3.0 1.2 -2.4 -1.9 -1.6 -2.1 -2.9 -2.3 -0.2 -2.4 -2.1
Irritable Bowel Disease (IBD) 4.4 10.6 22.8 -3.1 -3.8 -3.6 -3.6 -2.9 -3.1 -2.9 -2.2 -2.7 -3.1 -2.8 -3.8 -3.9 -3.3 -4.1 3.4 -1.0 -3.6 -3.6 -3.5 -3.8 -3.6 -3.3 -3.6 -3.6 -3.5 -3.6 -1.1 -2.1 -3.6 -4.2 -2.8 0.0 -3.8 -3.9 -4.1 -3.6 -4.8 -1.3 3.9 0.9 -3.3 -2.9 -2.6 -2.9 -3.7 -3.2 -0.7 -3.5 -3.0
Ulcerative Colitis (UC) 4.8 9.1 16.4 -3.2 -3.2 -3.4 -3.2 -2.4 -2.7 -2.9 -2.3 -2.5 -3.2 -2.6 -3.6 -3.5 -3.0 -3.8 3.0 -1.2 -3.4 -3.4 -3.5 -3.5 -3.5 -3.0 -3.4 -3.4 -3.2 -3.5 -1.4 -2.3 -3.4 -3.5 -2.8 -0.6 -3.5 -3.3 -3.8 -3.4 -4.0 -1.4 3.1 0.5 -3.0 -2.8 -2.7 -2.4 -3.1 -3.1 -1.0 -3.5 -3.0
Major Depression (MDD) 0.3 0.3 1.8 0.4 0.3 -0.1 1.0 0.8 0.5 0.3 0.7 0.5 0.6 -1.1 0.0 0.4 -0.1 0.4 0.5 0.6 -0.1 0.5 -0.0 0.3 0.1 0.4 0.0 -0.0 0.6 0.1 0.8 0.4 -0.0 0.1 0.5 -1.2 0.1 0.0 -0.0 -0.1 0.3 0.6 0.8 1.3 0.7 0.4 0.4 1.3 0.1 0.3 0.6 0.4 0.5
Reaction Time 5.1 9.8 16.6 -3.5 -3.7 -3.3 -3.1 -3.1 -3.2 -3.3 -2.7 -3.8 -3.4 -2.5 -3.4 -3.5 -2.5 -3.5 2.5 -2.2 -3.2 -3.8 -3.3 -3.3 -3.5 -4.1 -3.3 -3.3 -3.4 -3.4 -2.1 -3.2 -3.3 -3.1 -3.2 -1.6 -3.4 -3.0 -3.0 -3.3 -3.3 -2.5 1.6 -0.6 -3.5 -3.6 -3.4 -2.4 -2.6 -3.0 -2.1 -3.6 -3.5
Verbal and Numeric Reasoning (VNR) 0.7 1.7 3.7 1.5 1.1 1.2 0.8 1.7 1.2 1.9 1.3 1.5 1.6 1.2 1.6 1.1 0.7 0.7 -0.8 1.2 1.2 1.3 1.1 1.4 1.4 0.9 1.2 1.2 1.5 1.4 1.5 1.4 1.4 0.6 1.9 1.2 1.3 1.0 1.4 1.2 0.6 1.5 0.1 1.1 1.7 1.6 1.6 0.8 1.2 1.6 1.2 1.6 1.5
Breast Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Ovarian Cancer 3.2 4.2 10.8 -2.1 -2.3 -2.3 -1.1 -2.1 -2.2 -2.1 -3.3 -2.5 -2.1 -0.9 -2.5 -1.7 -1.8 -2.0 1.7 -0.7 -2.3 -2.2 -2.1 -1.9 -2.4 -2.1 -2.4 -2.3 -2.5 -2.4 -0.8 -2.0 -2.3 -2.0 -2.3 -1.9 -2.4 -1.3 -2.0 -2.3 -1.8 -1.8 1.1 -1.0 -2.5 -2.3 -2.1 -1.6 -1.8 -2.1 -1.0 -2.2 -2.3
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.2 0.3 1.7 0.3 -0.3 -0.5 0.9 0.1 -0.7 -0.1 -0.2 0.1 0.2 0.4 -0.3 -0.2 -0.8 -0.4 0.8 1.2 -0.5 -0.0 -1.2 0.2 -0.2 -0.3 -0.5 -0.6 -0.0 -0.3 0.7 0.4 -0.5 -0.6 -0.3 -0.6 -0.5 -0.1 -0.3 -0.5 -0.6 1.3 -0.1 0.7 0.1 0.3 0.4 0.9 0.3 -0.1 1.1 0.0 0.1
Bipolar Disorder (2011) 0.8 0.7 2.7 -0.1 1.1 1.0 0.2 -0.0 1.2 0.6 0.0 1.1 -0.2 -0.9 0.3 0.8 1.6 0.8 -1.4 -1.6 0.9 0.7 1.4 0.2 0.5 1.0 0.9 1.0 0.1 0.7 -1.5 -0.3 0.7 1.5 -0.6 0.5 0.8 1.1 0.2 0.0 1.3 -0.8 -1.2 -0.9 0.2 -0.1 -0.3 -0.5 0.2 -0.2 -1.5 0.0 0.2
Body Mass Index (BMI) (2010) 0.1 0.2 2.6 0.2 0.1 0.4 -0.7 -0.0 0.2 -0.2 0.4 0.9 0.1 0.3 0.2 -0.3 0.4 -0.2 -0.2 -0.2 0.4 0.4 0.0 -0.1 0.3 0.9 0.4 0.4 0.1 0.3 -0.3 0.2 0.3 -0.0 0.4 1.6 0.3 -0.6 0.1 0.4 -0.6 0.7 -0.9 -0.0 0.7 0.3 0.3 -0.0 0.5 0.2 0.0 0.3 0.2
Coronary Artery Disease (CAD) 0.9 1.1 5.2 1.4 0.8 0.6 0.6 1.4 1.1 1.3 1.5 0.6 1.3 0.9 1.0 0.5 0.0 0.6 -0.0 1.6 0.6 0.8 0.8 1.1 1.0 0.9 0.7 0.6 1.2 0.8 1.4 1.7 0.8 0.4 0.9 0.1 0.8 0.4 0.5 0.6 0.6 1.3 0.5 1.4 1.0 1.8 1.8 1.0 0.8 1.1 2.3 1.2 1.4
Crohns Disease (2012) 0.6 1.0 4.7 -0.6 -1.3 -0.8 -1.3 -0.9 -1.8 -0.6 -0.0 -0.4 -0.5 -1.0 -0.8 -1.1 -0.8 -1.3 0.8 0.0 -0.8 -1.2 -1.0 -1.0 -0.7 -0.6 -0.8 -0.9 -0.9 -0.7 0.4 -0.3 -0.8 -1.3 -0.5 1.0 -0.9 -2.0 -1.0 -0.8 -1.9 -0.5 2.2 0.2 -1.2 -0.4 -0.3 -1.4 -2.0 -0.7 0.2 -0.8 -0.8
Mean Putamen Volume 1.5 1.7 3.3 1.2 1.5 1.4 1.4 1.6 1.4 1.4 1.7 1.4 1.1 0.9 1.8 1.3 1.4 1.1 -1.4 0.3 1.4 1.7 1.4 1.7 1.4 1.2 1.4 1.4 1.5 1.4 0.6 0.6 1.3 1.4 1.4 1.0 1.5 1.6 1.4 1.4 1.2 0.8 -0.5 0.2 1.5 1.4 1.2 1.1 1.6 1.7 0.3 1.4 1.4
Fasting Glucose 4.0 4.8 8.9 2.5 2.1 2.7 1.6 1.6 2.7 2.1 2.1 2.0 2.4 0.8 2.4 2.7 2.3 2.2 -2.1 0.8 2.7 2.6 2.5 2.4 2.7 2.5 2.6 2.7 2.4 2.7 0.9 2.0 2.7 1.9 3.0 2.4 2.7 2.6 2.5 2.7 2.3 1.5 -1.0 0.8 1.3 2.0 2.2 0.8 1.2 1.7 0.6 2.5 2.3
HbA1C 1.9 2.1 4.0 1.9 1.6 1.2 1.3 1.8 2.0 1.9 1.7 1.4 1.9 1.0 1.6 1.5 0.8 1.2 -0.6 1.4 1.2 2.0 1.5 1.5 1.5 1.6 1.2 1.2 1.6 1.4 1.8 1.9 1.1 0.9 1.5 0.5 1.3 1.0 1.0 1.2 1.2 1.5 -0.6 0.9 2.0 1.6 1.6 1.1 1.9 1.2 1.4 1.8 1.6
HDL Cholesterol 0.2 0.3 2.9 -0.6 -0.0 -0.2 0.2 -0.9 -0.2 -0.3 -1.7 -0.2 -0.5 -0.0 -0.4 -0.0 0.3 0.5 -0.3 -0.4 -0.2 -0.1 -0.2 -0.4 -0.4 -0.2 -0.2 -0.2 -0.8 -0.3 -0.5 -0.4 -0.1 0.4 -0.5 -1.5 -0.3 0.5 -0.0 -0.2 0.6 -1.2 -1.4 -1.2 -0.3 -0.4 -0.5 0.3 0.2 -0.6 -0.5 -0.3 -0.4
LDL Cholesterol 1.0 1.5 5.9 1.2 1.0 1.6 0.8 1.3 1.2 0.5 0.3 0.6 1.6 0.4 1.6 1.1 1.3 0.7 -1.4 0.2 1.6 1.1 1.1 1.4 1.6 0.9 1.6 1.6 1.4 1.7 0.4 1.0 1.6 1.0 1.3 2.4 1.7 1.0 1.6 1.7 0.9 1.1 0.0 0.4 1.0 0.9 1.1 0.7 0.5 1.8 0.1 1.6 1.2
Lupus 0.1 0.1 0.6 0.1 -0.2 -0.1 -0.2 0.3 -0.4 -0.5 -0.0 -0.2 0.1 0.1 0.0 -0.0 -0.2 -0.2 0.3 0.4 -0.1 -0.1 -0.2 0.2 0.0 -0.5 -0.1 -0.2 0.2 -0.1 0.4 -0.4 -0.1 -0.1 -0.1 -0.7 -0.1 -0.1 0.3 -0.1 -0.1 0.5 -0.4 0.0 0.2 0.2 0.2 -0.3 0.8 0.0 0.5 -0.0 -0.0
Neuroticism (2016) 0.1 0.2 3.4 0.2 -0.2 -0.3 0.6 0.2 0.3 0.2 0.1 -0.5 -0.0 -1.9 -0.5 -0.2 -0.2 -0.3 0.3 0.2 -0.3 0.1 0.4 -0.1 -0.2 -0.1 -0.3 -0.3 0.1 -0.3 0.1 0.0 -0.3 -0.2 -0.7 -0.5 -0.3 -0.4 -0.3 -0.3 0.2 0.1 0.5 0.1 -0.2 -0.4 -0.4 -0.4 -0.3 -0.2 -0.2 -0.1 -0.0
Primary Biliary Cirrhosis 0.1 0.1 0.9 -0.4 0.4 0.2 -0.6 -0.2 0.5 0.4 -0.4 0.1 -0.3 -0.3 0.1 0.0 0.6 0.1 -0.3 -0.9 0.1 0.1 0.2 -0.2 -0.1 0.1 0.1 0.2 -0.0 0.0 -0.5 -0.5 0.1 0.4 -0.0 0.1 0.1 0.2 0.0 0.2 0.7 -0.8 0.3 -0.3 -0.2 -0.5 -0.4 -1.0 -0.4 -0.3 -0.9 -0.3 -0.2
Rheumatoid Arthritis 0.2 0.2 1.3 -0.6 -0.4 0.1 -0.7 -0.4 -0.6 -0.8 -0.6 -0.1 -0.4 -0.1 -0.2 -0.1 0.3 -0.2 -0.4 -1.1 0.1 -0.4 -0.1 -0.3 -0.1 0.0 0.1 0.1 -0.3 0.0 -0.8 -0.8 0.3 0.2 0.3 0.7 0.1 0.3 -0.0 0.1 -0.5 -0.5 0.3 -0.2 -0.7 -0.6 -0.6 -0.6 -1.1 -0.4 -1.1 -0.4 -0.6
Schizophrenia (2014) 0.2 0.5 3.9 0.8 1.0 0.3 0.8 1.2 1.5 0.8 -0.0 -0.1 0.8 -0.3 0.5 0.6 0.2 0.8 -0.0 0.6 0.3 0.9 1.0 0.5 0.4 0.0 0.3 0.4 0.8 0.4 0.6 0.3 0.2 0.7 -0.0 -2.0 0.5 1.3 0.4 0.3 1.8 -0.0 0.7 0.0 0.7 0.4 0.4 0.3 0.5 0.5 0.5 0.6 0.6
Triglycerides 1.6 2.6 5.4 2.0 1.4 1.7 1.4 2.0 1.1 1.8 1.9 1.4 1.9 0.8 2.3 1.4 1.0 1.5 -1.2 1.0 1.7 1.7 1.4 2.1 2.0 1.9 1.7 1.7 2.2 1.8 1.0 1.8 1.5 1.2 1.3 1.7 1.9 1.1 1.5 1.7 1.0 1.6 -0.8 0.5 1.7 1.8 1.9 1.0 1.6 1.8 1.2 2.0 1.7
Type 2 Diabetes (T2D) (2012) 0.7 0.8 2.2 1.3 0.9 0.6 0.6 1.0 0.8 0.1 1.3 1.3 1.4 -0.4 0.8 0.6 0.3 0.5 0.1 -0.8 0.7 1.3 0.2 0.8 1.0 1.1 0.7 0.6 1.2 0.9 1.5 0.1 0.6 0.4 1.2 0.2 0.8 -0.6 0.2 0.6 0.5 1.2 -0.4 0.5 1.0 1.2 1.3 1.1 1.3 0.8 1.4 1.3 0.7
Ulcerative Colitis 2.0 2.9 6.4 -1.8 -1.7 -2.0 -2.2 -1.3 -1.9 -1.4 -0.7 -1.2 -1.5 -1.4 -2.0 -1.9 -1.9 -2.2 1.9 -0.2 -1.9 -2.1 -2.1 -2.0 -2.0 -1.9 -1.9 -2.0 -1.7 -1.9 -0.1 -1.0 -2.0 -1.9 -1.4 -1.0 -2.0 -1.7 -2.2 -2.0 -2.3 -0.9 2.5 0.3 -1.6 -1.3 -1.4 -1.3 -1.6 -1.2 -0.1 -1.8 -1.5
Blood Eosinophil Count 0.7 5.2 8.0 2.6 2.8 2.4 1.7 2.2 1.6 2.8 1.9 2.8 2.6 1.9 2.4 2.2 2.2 2.5 -1.7 1.7 2.4 2.1 1.9 2.6 2.6 2.7 2.5 2.4 2.2 2.5 1.4 2.5 2.5 2.5 2.6 2.3 2.4 1.7 2.5 2.4 2.2 1.6 -2.0 -0.3 2.4 2.8 2.6 2.1 2.1 2.4 1.7 2.7 2.5
Blood Platelet Count 0.7 8.5 15.7 3.6 2.6 2.5 2.6 3.8 3.5 3.4 3.0 2.7 3.5 2.2 3.6 1.9 1.4 1.9 -1.2 3.1 2.4 3.4 2.4 3.5 3.0 2.3 2.5 2.5 3.6 2.8 3.3 4.0 2.5 1.6 3.8 3.6 2.9 2.0 2.3 2.5 1.8 3.5 -0.1 2.3 3.5 3.4 3.5 3.7 2.4 3.5 3.0 3.3 3.5
Blood Red Count 0.3 2.9 10.8 1.7 1.7 2.0 2.3 0.9 1.6 2.4 0.3 -0.1 1.7 0.9 1.6 2.3 1.9 2.9 -1.7 0.8 2.0 2.1 2.2 1.7 1.9 1.3 1.8 1.9 1.6 2.0 0.5 1.1 2.1 2.0 1.4 -1.6 1.9 1.1 2.6 2.0 3.3 -0.9 -0.6 -0.9 1.1 1.2 1.6 1.1 1.0 1.6 0.6 1.7 1.7
Blood White Count 2.3 17.1 26.8 -4.3 -5.2 -4.5 -4.8 -3.6 -2.9 -4.5 -3.7 -4.6 -4.5 -2.6 -5.0 -5.0 -3.6 -4.9 3.8 -2.5 -4.5 -4.3 -4.2 -4.9 -4.7 -4.7 -4.7 -4.5 -4.5 -4.7 -2.6 -4.3 -4.4 -4.9 -3.9 -1.1 -4.6 -4.7 -4.6 -4.5 -4.8 -2.2 2.5 0.9 -3.7 -4.7 -4.2 -3.5 -3.6 -4.7 -2.3 -4.5 -4.2
Heel T-Score 0.4 3.0 19.5 -0.3 1.5 1.9 0.8 -1.6 -0.2 0.2 -1.4 1.3 -0.1 1.5 0.8 1.5 2.5 2.3 -2.7 -1.8 2.0 0.3 1.6 0.4 1.2 1.6 1.9 1.9 -0.4 1.5 -1.8 -0.5 2.0 2.7 0.7 0.0 1.5 1.8 2.3 1.9 2.1 -3.2 -4.4 -4.4 -0.1 -0.0 -0.3 0.2 0.8 0.2 -2.3 0.5 -0.1
BMI 2.3 13.3 30.0 3.6 4.3 4.2 2.0 3.1 3.6 3.8 3.7 5.4 3.5 3.6 3.8 3.3 3.6 3.4 -3.5 1.2 4.2 4.2 3.7 3.6 4.1 4.9 4.3 4.2 3.7 4.2 1.2 2.9 4.2 3.8 3.8 5.5 4.2 3.2 4.0 4.2 2.8 2.8 -3.8 -0.1 4.0 3.9 3.4 2.5 2.9 3.3 1.2 3.9 3.7
Height 2.7 52.1 93.2 -6.3 -8.7 -8.2 -5.0 -5.7 -5.0 -7.4 -4.1 -9.3 -6.8 -9.7 -8.5 -7.5 -7.5 -7.5 7.5 -2.7 -8.3 -7.5 -7.5 -7.1 -8.1 -8.0 -8.6 -8.2 -6.2 -8.3 -3.7 -6.5 -8.0 -8.4 -8.1 -4.9 -8.2 -7.7 -8.2 -8.2 -6.7 -0.9 9.2 5.8 -7.7 -7.2 -6.1 -5.8 -8.7 -8.0 -1.7 -7.6 -6.3
Waist Hip Ratio (WHR) 0.1 0.6 4.3 0.6 0.8 0.8 -0.2 0.4 -0.7 0.6 -0.6 1.2 0.9 -2.1 0.6 0.8 1.1 0.7 -0.8 0.2 0.9 0.6 0.6 0.2 0.9 1.3 1.0 0.8 0.6 0.9 0.4 0.8 0.8 1.2 -0.1 1.0 0.8 0.3 0.6 0.8 0.2 0.3 0.5 -0.7 0.3 1.0 0.5 -0.7 -0.3 0.8 0.3 0.9 0.4
Systolic Blood Pressure 1.4 7.2 21.0 2.8 2.5 2.4 2.2 2.8 3.1 3.2 4.6 2.8 3.0 4.3 2.9 2.1 1.6 1.6 -1.6 2.2 2.4 3.0 2.2 2.5 2.7 2.4 2.4 2.4 3.1 2.6 2.8 2.3 2.8 1.5 4.3 3.2 2.6 0.8 3.0 2.4 1.6 2.7 0.5 3.3 3.2 2.8 2.8 2.2 1.9 3.1 1.8 2.9 3.1
Smoking Status 1.3 3.1 15.8 1.9 1.9 1.0 1.2 2.2 1.1 1.3 1.4 4.0 1.9 2.1 1.3 0.4 0.5 0.8 -0.3 2.0 1.0 2.4 0.9 1.4 1.4 3.0 1.3 1.0 1.4 1.3 2.2 2.2 1.1 0.8 1.9 2.4 1.1 1.3 0.8 1.0 0.4 3.0 -1.6 1.5 2.6 2.4 1.9 1.5 2.2 1.1 1.9 2.1 2.0
Allergy or Eczema 0.2 0.6 2.3 0.1 0.5 1.0 -0.5 -0.4 0.1 1.0 0.6 0.5 0.1 0.8 0.9 1.0 1.4 0.6 -1.4 -0.9 1.0 0.2 0.8 0.5 0.7 0.5 0.9 0.9 0.3 0.8 -0.8 -0.1 1.0 1.0 0.4 1.0 0.8 1.0 1.0 1.0 0.7 -1.0 -0.8 -1.5 -0.0 0.1 0.1 -0.8 -0.2 0.2 -0.8 0.2 0.2
Cardiovascular Disease 7.0 23.3 36.6 5.5 5.5 4.6 4.0 6.0 5.9 5.7 5.4 5.5 5.5 4.4 5.1 3.9 2.9 4.0 -3.1 3.9 4.5 5.7 4.6 5.1 5.1 4.8 4.7 4.7 5.8 5.0 4.2 5.4 4.8 3.8 6.0 3.8 4.9 3.6 4.6 4.6 4.2 5.0 -1.6 3.0 6.1 5.5 5.3 4.0 5.0 5.5 3.6 5.6 5.7
Hypothyroidism (self reported) 0.4 0.9 3.0 -0.0 -1.2 -1.2 -0.4 0.4 -0.7 -0.8 -0.2 -1.0 -0.4 0.3 -1.0 -1.4 -1.7 -1.1 1.7 1.1 -1.1 -0.2 -1.6 -0.4 -0.7 -1.2 -1.1 -1.2 -0.5 -1.0 0.6 0.4 -1.1 -1.7 -0.3 0.2 -1.0 -1.4 -1.2 -1.2 -1.5 1.0 0.6 1.5 -0.1 -0.1 0.0 0.1 0.6 -0.6 1.2 -0.5 -0.1
Respiratory disease 0.7 1.6 4.1 -0.6 -1.6 -1.7 -0.8 -0.1 -0.8 -0.5 -1.2 -1.9 -0.8 -0.3 -1.1 -1.4 -1.8 -1.1 2.0 0.9 -1.7 -1.1 -1.2 -1.1 -1.3 -1.9 -1.7 -1.7 -0.8 -1.5 0.6 -0.5 -1.7 -1.8 -1.6 -1.8 -1.5 -1.8 -1.5 -1.7 -1.4 0.1 1.4 -0.0 -0.7 -0.8 -0.6 -0.6 -0.5 -0.9 0.8 -1.0 -0.8
Type 2 Diabetes (T2D) (2018) 1.8 3.4 8.0 2.0 2.3 2.1 1.1 1.8 1.5 2.2 1.8 2.8 2.0 0.1 2.0 1.9 1.7 1.9 -1.6 0.8 2.1 1.9 1.6 2.0 2.2 2.7 2.2 2.1 2.0 2.2 0.9 1.6 2.0 2.0 1.6 1.8 2.1 1.2 1.9 2.1 1.6 1.6 -1.4 0.1 2.1 2.2 1.9 1.0 1.4 1.6 1.0 2.2 1.9
Lung FEV1/FVC ratio 0.7 3.4 9.4 0.8 2.1 2.4 1.6 0.2 1.4 1.5 0.2 2.5 1.3 1.9 1.6 1.8 2.6 1.7 -2.8 -0.6 2.4 1.4 2.1 1.6 1.9 2.5 2.4 2.4 0.8 2.2 -0.2 0.6 2.4 2.5 1.8 2.3 2.2 3.1 2.8 2.4 1.8 -0.9 -2.5 -1.9 1.1 1.2 0.9 0.8 1.1 1.8 -1.1 1.6 1.1
Lung FVC 0.2 0.8 7.3 -0.3 0.3 0.8 -0.2 -0.9 -0.2 0.4 -0.8 0.2 -0.1 2.7 0.7 0.7 1.1 1.0 -1.2 -0.6 0.8 0.1 0.9 0.1 0.4 0.6 0.7 0.8 -0.1 0.6 -0.7 -0.5 1.0 0.7 0.8 0.3 0.7 0.9 1.5 0.8 0.7 -1.9 -1.2 -2.3 -0.1 -0.3 -0.3 -0.5 -0.1 0.1 -1.2 0.2 -0.1
Neuroticism 0.1 0.2 3.2 0.4 -0.2 -0.2 0.4 0.3 0.1 0.0 -0.6 -0.9 0.5 -1.8 -0.3 0.1 -0.4 -0.1 0.5 0.6 -0.2 0.2 -0.2 0.1 0.0 -0.3 -0.3 -0.2 0.2 -0.0 0.5 0.4 -0.4 -0.4 -0.9 -0.9 -0.2 0.1 -0.3 -0.2 0.2 0.9 0.3 -0.1 0.3 0.1 0.3 -0.4 -0.1 -0.1 0.8 0.4 0.2
Chronotype (morning person) 2.4 5.6 16.5 1.5 2.7 2.9 2.0 1.4 2.3 2.2 2.2 3.8 1.7 2.9 2.6 2.4 3.2 2.1 -3.2 -0.5 2.9 2.7 2.7 2.1 2.4 3.3 2.9 2.9 2.2 2.7 -0.2 1.5 3.0 2.6 3.0 4.1 2.8 1.9 2.7 2.9 1.9 1.0 -2.3 -0.3 2.0 1.7 1.5 0.8 1.5 2.0 -0.7 2.0 1.9
Hair Pigment 0.0 0.7 2.2 0.7 1.0 1.0 0.8 0.4 0.9 1.1 0.9 1.0 0.8 1.3 0.8 1.2 0.7 1.1 -1.0 0.3 1.0 0.7 0.9 0.8 0.9 1.0 1.0 1.0 0.6 1.0 0.5 0.9 1.1 0.9 1.5 0.4 0.9 0.4 0.8 1.0 1.1 0.5 -0.9 0.9 0.9 0.7 0.8 0.5 0.4 0.8 0.1 0.9 0.8
Tanning 0.1 1.1 3.3 1.0 1.5 1.1 1.0 0.6 0.6 1.4 0.5 1.7 0.3 0.7 0.5 1.0 1.3 1.2 -1.4 0.7 1.1 0.3 1.2 0.6 1.2 1.0 1.3 1.1 0.6 1.0 -0.7 0.7 1.3 1.8 1.2 0.1 0.9 1.1 1.3 1.1 1.3 -0.2 -1.0 -0.6 0.6 1.4 1.1 1.0 1.1 1.0 0.5 0.5 1.0
Hand grip strength (left) 0.1 0.2 4.2 0.2 0.2 -0.0 1.0 -0.1 0.4 -0.1 -0.5 -0.6 -0.0 -1.1 -0.5 0.2 -0.1 0.5 0.2 0.1 -0.1 0.0 -0.1 -0.0 -0.0 0.2 -0.1 -0.0 -0.0 -0.1 -0.1 -0.4 -0.1 0.2 -0.2 -2.1 -0.1 0.4 0.2 -0.0 1.0 -0.1 -0.3 -0.4 -0.0 -0.1 0.1 -0.0 -0.3 -0.7 0.2 -0.1 0.1
Number of treatments/medications taken 6.4 11.5 18.7 3.7 4.0 3.2 3.1 4.2 3.7 3.7 3.7 4.3 4.0 1.5 3.4 2.9 2.3 2.9 -2.2 2.4 3.2 4.0 3.0 3.5 3.6 3.7 3.4 3.3 4.1 3.5 3.2 3.5 3.3 3.0 3.7 3.0 3.4 2.3 3.2 3.2 2.9 3.6 -1.3 1.9 4.3 4.0 3.6 3.3 3.8 4.3 2.4 4.1 3.9
Average weekly spirits intake 1.6 2.0 6.6 1.7 1.9 0.8 0.4 2.6 2.4 1.8 2.0 1.7 1.6 -0.1 1.1 0.7 0.4 0.9 -0.1 1.6 0.8 2.0 1.3 0.9 1.1 1.5 1.0 0.9 2.0 1.0 1.7 1.4 0.9 0.8 1.8 0.1 1.0 1.0 0.8 0.8 1.3 1.8 1.3 1.6 2.0 1.8 1.5 1.1 1.6 1.6 1.5 1.5 1.9
Sensitivity / hurt feelings 0.4 0.6 3.3 1.1 0.2 0.0 0.6 1.5 0.8 0.9 -0.1 -0.3 1.2 -0.4 0.4 0.2 -0.7 -0.1 0.7 1.6 0.0 0.9 -0.2 0.8 0.4 -0.2 0.0 0.1 0.9 0.3 1.8 1.6 -0.0 -0.3 0.4 -0.6 0.2 -0.2 -0.2 0.0 0.3 1.3 0.4 0.6 0.8 0.8 1.0 0.8 1.0 0.9 1.6 0.9 0.8
Frequency of depressed mood in last 2 weeks 0.6 0.8 3.6 0.5 -0.6 -0.8 0.7 1.1 -0.2 -0.1 -0.1 -0.1 0.5 -0.4 -0.3 -0.6 -1.4 -0.6 1.6 1.7 -0.8 0.2 -1.2 0.4 -0.3 -0.6 -0.7 -0.8 0.2 -0.5 1.7 0.7 -0.8 -1.0 -0.4 -1.0 -0.7 -0.6 -0.8 -0.8 -0.9 1.7 0.7 1.9 0.3 0.6 0.7 1.7 0.6 0.1 1.7 0.3 0.3
Hearing difficulty/problems: Yes 1.0 1.5 4.9 -0.5 -1.0 -1.8 -1.2 0.2 -1.0 -0.6 -1.2 -0.4 -0.6 -0.5 -1.2 -1.3 -2.1 -1.4 2.2 1.0 -1.8 -0.6 -1.8 -0.9 -1.4 -1.1 -1.6 -1.8 -0.6 -1.6 0.7 -0.2 -1.7 -1.5 -1.2 -1.3 -1.6 -1.3 -1.9 -1.8 -1.4 0.6 1.3 0.4 -0.4 -0.3 -0.5 -0.3 0.0 -0.9 1.1 -0.8 -0.7
Relative age of first facial hair 0.2 0.3 1.2 -0.6 -0.3 -0.6 -0.3 -0.2 -0.2 -0.8 -0.5 -0.2 -0.5 -1.1 -0.9 -0.5 -0.4 -0.6 0.4 -0.4 -0.6 -0.3 -0.7 -0.7 -0.7 -0.4 -0.6 -0.6 -0.6 -0.6 -0.1 -1.1 -0.5 -0.3 -0.1 -1.1 -0.7 -0.8 -0.6 -0.6 -0.3 0.2 -0.5 0.6 -0.1 -0.5 -0.5 0.5 0.2 -0.6 -0.3 -0.5 -0.5
Other serious medical condition/disability diagnosed by doctor 0.3 0.3 1.8 0.5 -0.1 -0.5 1.0 0.6 0.3 0.2 0.1 -0.0 0.3 -0.4 -0.1 -0.1 -1.0 -0.3 0.9 1.2 -0.4 0.7 -0.3 0.3 -0.1 -0.2 -0.4 -0.4 0.2 -0.3 0.7 0.6 -0.4 -0.6 -0.1 0.2 -0.4 -0.3 -0.4 -0.5 -0.4 1.2 0.8 1.3 0.3 0.6 0.6 0.7 1.0 0.2 1.2 0.2 0.4
Ever used hormone-replacement therapy (HRT) 0.4 0.6 1.8 0.6 0.9 0.7 0.6 0.9 0.9 0.5 0.5 1.3 0.9 0.4 0.8 0.6 0.5 0.5 -0.7 0.2 0.7 0.9 0.6 0.8 0.7 1.2 0.8 0.7 0.7 0.8 0.5 0.8 0.7 0.7 0.5 1.0 0.8 0.9 0.6 0.7 0.6 0.5 -0.6 0.5 1.0 0.8 0.7 1.2 0.7 0.8 0.2 1.0 0.7
Ever had hysterectomy (womb removed) 0.7 0.8 5.6 0.5 -0.5 -0.9 0.1 1.0 -0.0 0.3 0.6 -0.2 0.4 -0.4 -0.1 -1.2 -1.7 -1.0 1.6 1.6 -0.9 0.1 -0.5 -0.1 -0.4 -0.2 -0.8 -0.9 -0.0 -0.6 1.7 1.1 -0.7 -1.3 -0.3 0.2 -0.7 -0.8 -0.8 -0.9 -1.2 1.3 0.8 2.4 0.5 0.5 0.6 1.3 1.0 0.2 1.7 0.2 0.3
Systolic blood pressure, automated reading 2.0 5.9 18.7 3.1 2.1 1.6 2.0 3.0 3.0 3.2 4.3 1.8 3.1 3.2 2.3 1.8 0.5 1.5 -0.4 3.0 1.6 2.7 1.4 2.4 2.3 1.7 1.6 1.7 3.1 2.1 3.5 3.0 1.8 0.8 3.2 1.1 2.0 0.9 2.0 1.6 1.7 3.0 1.0 3.1 3.0 2.7 2.9 2.4 1.9 2.7 2.9 2.8 3.1
Eye problems/disorders: Diabetes related eye disease 1.2 1.3 4.5 1.7 0.3 0.7 0.7 1.7 1.4 1.0 0.9 -0.1 1.9 0.1 1.2 0.8 -0.4 0.6 0.1 1.9 0.7 1.4 0.3 1.4 1.1 0.2 0.6 0.7 1.6 1.0 2.1 1.5 0.7 -0.1 0.8 0.5 0.9 -0.0 0.6 0.7 0.6 2.1 1.3 1.6 1.4 1.3 1.6 1.1 0.5 1.3 1.9 1.6 1.5
Angina 2.2 2.9 7.6 1.9 1.6 1.1 2.4 2.5 1.0 1.8 1.7 2.3 2.2 0.7 1.9 1.2 0.6 1.4 -0.5 1.9 1.2 1.9 0.8 2.1 1.6 2.0 1.3 1.1 1.9 1.5 2.3 2.4 1.3 1.1 1.5 -0.2 1.4 0.5 1.0 1.1 1.2 2.1 -1.1 2.0 2.2 2.2 2.0 2.8 2.2 1.5 1.9 2.3 1.9
Medication for hormone replacement therapy 0.5 0.6 1.7 -0.5 -0.7 -1.1 -0.4 0.2 -0.3 -0.3 -0.2 -0.4 -0.5 -0.4 -0.7 -0.8 -1.2 -0.7 1.3 0.1 -1.1 -0.5 -1.3 -0.6 -1.0 -0.2 -1.1 -1.1 -0.6 -1.0 0.2 -0.6 -1.1 -1.1 -0.9 -1.1 -1.0 -0.9 -0.8 -1.1 -0.6 0.3 0.8 0.5 -0.5 -0.5 -0.5 0.4 -0.6 -0.8 0.2 -0.6 -0.6
Vitamin and mineral supplements 0.2 0.3 1.8 0.1 0.5 -0.5 0.2 1.2 1.0 -0.0 0.3 0.7 -0.2 1.3 -0.2 -0.4 -0.6 -0.4 0.8 0.5 -0.6 0.2 -0.4 -0.1 -0.5 -0.1 -0.4 -0.4 0.0 -0.5 0.5 0.5 -0.5 -0.3 -0.1 -0.6 -0.4 0.2 -0.8 -0.5 0.0 0.7 0.3 0.6 0.8 0.1 -0.2 0.4 -0.0 -0.5 0.3 -0.2 0.1
Supplements: Zinc 0.6 0.6 1.8 0.3 1.0 1.0 0.1 -0.2 0.2 -0.1 -0.1 1.3 0.7 -0.9 0.4 0.7 1.2 0.9 -1.3 -0.7 1.1 0.3 1.1 -0.0 0.8 1.2 1.1 1.0 0.3 1.0 -0.2 -0.4 1.0 1.3 0.6 1.2 0.9 0.7 1.0 1.0 0.7 -0.2 -0.6 -0.7 0.7 0.6 0.3 -0.7 0.4 0.5 -0.5 0.7 0.4
Medication: Co-codamol 2.3 2.7 5.8 1.9 1.7 1.4 1.3 2.0 2.0 1.9 2.4 2.0 1.9 0.1 1.9 1.4 0.8 1.4 -0.8 1.5 1.4 2.2 1.4 1.7 1.6 2.0 1.4 1.4 1.9 1.6 1.9 2.0 1.3 1.0 1.4 2.0 1.5 0.5 1.1 1.4 1.1 1.9 -0.1 1.5 2.2 1.9 1.9 1.9 1.4 1.8 1.5 1.8 1.9
Medication: Metformin 0.8 1.2 3.2 0.8 1.2 1.4 0.8 0.3 1.0 1.2 1.2 1.6 1.0 0.3 1.0 1.2 1.6 1.3 -1.3 -0.2 1.4 0.9 0.8 0.8 1.2 1.8 1.4 1.4 0.9 1.4 0.3 0.5 1.2 1.4 1.0 1.1 1.3 0.9 1.2 1.4 1.1 0.4 -1.6 -0.5 1.1 0.9 0.8 0.2 0.8 0.7 -0.2 1.2 0.9
Diabetes (father) 0.2 0.2 2.3 0.3 0.0 -0.1 -0.1 0.4 0.4 0.8 0.2 -0.0 0.4 -1.5 -0.0 -0.2 -0.3 -0.1 0.3 0.5 -0.2 -0.1 0.2 -0.3 0.0 -0.0 -0.1 -0.1 -0.0 -0.0 0.8 0.6 -0.1 -0.3 -0.5 0.1 -0.2 -0.7 -0.4 -0.1 -0.3 0.8 1.1 0.7 0.3 0.3 0.3 0.2 -0.2 0.4 0.6 0.3 0.2
Diabetes (mother) 1.3 1.7 8.8 0.2 1.0 1.7 -0.6 -0.6 1.3 0.9 0.1 1.0 0.1 0.5 0.9 1.3 2.2 1.1 -2.4 -1.7 1.7 0.7 1.6 0.4 1.1 1.5 1.6 1.8 0.4 1.4 -1.6 0.3 1.6 1.7 0.8 3.0 1.5 1.4 1.3 1.7 1.2 -0.9 -1.7 -1.7 0.3 -0.0 -0.0 -1.1 -0.5 0.3 -1.7 0.5 0.4
Severe depression (siblings) 0.3 0.3 5.9 0.2 -0.1 0.5 0.2 -0.5 -0.2 0.2 1.4 0.2 0.1 -2.4 0.3 0.5 0.4 0.8 -0.4 -0.2 0.5 0.2 0.2 0.2 0.5 0.6 0.5 0.5 0.0 0.4 -0.4 -0.6 0.4 0.4 -0.1 -0.3 0.4 0.0 0.7 0.5 0.2 -0.3 -0.7 0.4 0.0 0.2 0.3 0.3 -0.5 -0.5 -0.1 0.2 0.2
Pack years adult smoking proportion 0.8 1.2 3.5 0.8 1.6 1.3 1.1 1.0 1.1 1.0 1.1 1.9 0.9 0.8 1.3 0.9 1.3 1.2 -1.2 0.1 1.3 1.2 1.2 0.9 1.1 1.4 1.4 1.3 1.1 1.2 0.4 0.9 1.3 1.6 1.5 1.0 1.3 1.2 1.1 1.3 1.0 0.5 -0.8 0.2 1.3 1.0 0.8 0.6 1.3 1.0 -0.1 1.1 1.0
Impedance of leg (right) 0.1 0.5 7.0 0.6 0.4 -0.2 0.8 0.8 -0.1 0.6 0.5 -0.4 0.6 -1.0 0.3 0.4 -0.6 0.4 0.6 1.3 -0.2 0.1 0.4 0.5 0.2 -0.1 -0.1 -0.2 0.4 0.0 1.7 1.0 -0.2 0.1 -0.0 -2.6 -0.0 -0.0 -0.2 -0.2 0.6 0.2 0.7 0.6 0.2 0.6 0.6 1.0 0.5 0.5 1.3 0.4 0.4
Leg fat-free mass (left) 0.3 1.6 3.8 -1.1 -1.5 -1.1 -1.1 -1.1 -0.2 -1.3 -0.4 -0.8 -1.3 -1.6 -1.6 -1.5 -0.8 -1.6 0.9 -1.2 -1.1 -1.2 -1.4 -1.3 -1.2 -0.8 -1.1 -1.0 -1.0 -1.2 -2.0 -1.6 -1.0 -1.4 -1.3 1.9 -1.2 -0.9 -1.1 -1.1 -1.7 0.8 0.9 1.7 -1.1 -1.2 -1.0 -1.3 -1.7 -1.7 -0.9 -1.4 -1.0
Trunk fat percentage 1.1 4.6 11.9 2.4 2.4 1.8 2.1 2.5 2.2 2.3 2.5 2.8 2.5 2.1 2.2 1.3 0.9 1.4 -1.0 1.8 1.8 2.6 1.5 2.6 2.1 2.1 1.9 1.8 2.6 2.0 2.1 2.4 1.8 1.5 2.2 2.5 1.9 1.2 1.6 1.8 1.1 3.5 -1.2 1.9 2.5 2.6 2.4 2.7 2.3 2.4 2.0 2.5 2.4
Hand grip strength (right) 0.7 1.9 3.6 -1.2 -1.1 -1.5 -1.4 -0.8 -0.6 -1.4 -1.7 -1.5 -1.4 -1.9 -1.9 -1.5 -1.5 -1.2 1.5 -0.7 -1.6 -1.4 -1.4 -1.4 -1.6 -1.4 -1.6 -1.5 -1.4 -1.6 -0.8 -1.9 -1.6 -1.4 -1.7 -1.9 -1.6 -0.5 -1.3 -1.5 -0.8 -0.4 0.8 -0.7 -1.1 -1.3 -1.3 -1.1 -1.4 -1.8 -0.4 -1.5 -1.3
Townsend deprivation index at recruitment 0.8 1.1 3.6 1.2 0.6 0.8 1.4 1.2 0.6 0.8 0.0 0.7 1.2 0.8 1.0 0.6 0.5 0.4 -0.3 1.6 0.8 0.8 0.5 1.4 1.1 0.7 0.9 0.8 1.1 1.0 1.2 1.6 0.9 0.6 1.3 1.4 0.9 0.5 0.8 0.8 0.2 1.4 -0.1 0.9 1.0 1.3 1.4 1.6 1.3 1.9 1.3 1.2 1.2
Current tobacco smoking 0.4 0.6 2.9 0.3 -0.2 -0.9 0.2 1.0 0.3 0.1 -0.5 0.3 0.3 1.2 -0.2 -1.0 -1.2 -1.0 1.4 1.4 -0.9 0.3 -0.8 -0.2 -0.5 -0.0 -0.8 -0.9 -0.0 -0.7 1.7 0.6 -0.9 -1.0 0.2 0.0 -0.8 -0.2 -1.1 -0.9 -0.9 1.4 1.1 1.3 0.5 0.3 0.3 0.8 0.5 0.1 1.3 0.2 0.2
Average weekly fortified wine intake 0.2 0.2 1.1 -0.4 -0.5 -0.3 0.4 -1.1 -0.7 -0.4 -0.4 -0.7 -0.3 -0.9 -0.5 -0.1 -0.1 -0.1 0.2 -0.1 -0.2 -0.4 -0.6 -0.4 -0.3 -0.1 -0.3 -0.3 -0.6 -0.3 -0.6 -0.1 -0.2 -0.2 -0.1 -0.9 -0.4 0.1 -0.1 -0.3 0.0 -1.0 -0.1 -0.5 -0.6 -0.4 -0.3 -0.2 -0.1 -0.3 -0.3 -0.4 -0.4
Maternal smoking around birth 0.2 0.3 4.5 -0.1 0.3 0.1 0.4 0.6 0.4 0.3 0.1 0.7 0.0 2.1 0.2 -0.2 0.4 -0.4 -0.4 -0.3 0.1 0.2 0.2 0.1 -0.0 0.4 0.1 0.1 0.2 0.1 0.0 0.6 0.2 0.1 0.9 2.1 0.1 0.1 -0.2 0.1 -0.4 0.4 -0.3 0.1 0.1 -0.0 -0.2 0.5 -0.4 0.3 -0.4 -0.0 -0.0
Fed-up feelings 0.2 0.4 1.8 0.7 0.6 -0.1 1.2 1.3 1.1 0.9 0.1 0.5 0.7 -0.6 -0.1 0.2 -0.3 -0.1 0.5 1.0 -0.1 0.6 -0.1 0.7 0.2 0.1 0.0 -0.0 0.5 0.1 1.1 0.9 -0.2 0.1 -0.0 -0.4 0.0 1.3 -0.1 -0.1 0.5 1.3 0.1 0.8 0.9 0.7 0.6 1.1 0.9 0.4 1.0 0.6 0.6
Frequency of unenthusiasm / disinterest in last 2 weeks 1.0 1.3 4.7 -1.5 -1.1 -1.0 -1.0 -0.8 -1.4 -1.8 -1.4 -0.1 -1.2 -0.8 -1.3 -1.4 -0.5 -1.8 0.6 -1.1 -1.0 -1.3 -1.5 -1.0 -1.2 -0.7 -0.9 -1.1 -1.4 -1.1 -0.8 -1.2 -1.1 -0.7 -1.1 1.3 -1.2 -1.0 -1.4 -1.0 -2.2 -0.1 -0.0 -0.1 -1.2 -1.0 -1.2 0.0 -0.6 -0.8 -1.1 -1.1 -1.5
Relative age voice broke 2.1 3.3 7.9 -2.4 -1.3 -1.4 -1.6 -2.1 -1.2 -2.6 -2.2 -0.8 -2.4 -1.9 -2.1 -1.3 -0.4 -1.4 0.4 -2.6 -1.5 -1.7 -1.3 -2.2 -2.0 -0.9 -1.5 -1.4 -2.3 -1.8 -2.3 -2.7 -1.5 -0.7 -1.8 -1.1 -1.6 -0.0 -1.7 -1.4 -0.8 -2.1 -0.6 -1.4 -1.6 -2.3 -2.4 -2.3 -1.2 -2.8 -2.5 -2.2 -2.1
Taking other prescription medications 1.4 2.2 6.5 1.3 1.7 1.8 1.7 0.9 1.3 1.6 1.0 1.6 1.5 0.1 1.3 1.6 1.5 1.4 -1.7 0.5 1.8 1.0 1.6 1.4 1.8 1.2 1.9 1.8 1.4 1.8 0.8 1.3 1.9 1.8 1.5 2.5 1.7 0.9 1.8 1.8 1.0 0.5 -1.1 0.2 1.2 1.6 1.4 1.1 1.3 2.1 0.4 1.6 1.4
Age when periods started (menarche) 0.4 1.0 4.5 -1.3 -0.6 0.0 -1.4 -1.6 -1.2 -1.2 -0.3 0.1 -1.2 -1.4 -0.6 -0.1 0.8 -0.3 -1.0 -2.1 0.1 -1.1 0.1 -0.8 -0.5 0.2 0.0 -0.0 -1.1 -0.2 -1.6 -1.1 0.0 0.3 -0.6 1.1 -0.2 0.1 -0.2 0.0 -0.5 -1.8 -1.2 -1.4 -1.1 -1.0 -1.2 -1.7 -0.9 -1.1 -2.0 -0.9 -1.2
Bilateral oophorectomy (both ovaries removed) 0.3 0.3 2.6 0.7 0.3 0.1 1.1 0.7 0.8 1.6 0.8 0.3 0.6 0.2 0.5 0.3 -0.4 0.1 0.3 1.0 0.0 0.2 0.5 0.5 0.3 0.1 0.1 0.1 0.3 0.2 1.1 0.8 -0.2 -0.1 -0.1 0.0 0.1 -0.1 0.2 0.1 -0.1 0.6 -0.4 0.3 0.7 0.7 0.8 1.2 0.7 0.5 1.1 0.5 0.6
Heel bone mineral density (BMD) T-score, automated (left) 0.4 0.8 2.9 0.5 0.7 1.3 0.1 -0.4 -0.2 0.6 0.0 0.8 0.5 1.3 0.8 1.1 1.2 1.5 -1.4 -0.0 1.3 0.2 1.2 0.3 1.1 0.8 1.3 1.2 0.3 1.1 -0.5 0.4 1.3 1.4 0.6 0.2 1.1 0.8 1.6 1.3 0.8 -1.1 -1.7 -1.6 0.3 0.6 0.4 -0.1 0.3 0.7 -0.4 0.6 0.4
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.7 0.8 0.5 0.1 1.2 1.0 1.0 0.8 -0.4 -0.2 0.8 0.1 0.4 0.3 -0.5 0.4 0.2 0.9 0.1 0.3 0.4 0.7 0.3 -0.2 0.1 0.1 0.8 0.3 1.2 0.9 0.1 0.0 -0.1 -0.4 0.3 0.1 -0.0 0.1 0.4 1.3 1.3 1.1 0.5 0.7 0.7 1.1 -0.1 0.9 1.1 0.6 0.7
Qualifications: CSEs or equivalent 1.6 2.1 5.9 -1.0 -2.2 -1.8 -1.3 -0.8 -0.8 -1.3 -0.0 -1.8 -1.1 0.1 -1.2 -1.9 -2.0 -2.1 1.9 0.2 -1.8 -0.8 -1.5 -1.2 -1.6 -1.8 -1.9 -1.8 -1.0 -1.7 0.3 -1.0 -1.8 -2.4 -1.0 -0.7 -1.7 -2.0 -1.9 -1.8 -2.1 0.4 1.9 1.5 -1.1 -1.3 -0.8 0.1 -1.0 -1.2 0.3 -1.3 -1.1
Serious illness, injury or assault to yourself 2.3 2.8 5.6 1.9 1.8 1.8 2.4 1.4 1.7 2.0 1.0 1.4 2.1 0.5 1.8 1.8 1.4 1.9 -1.2 1.4 1.8 1.8 1.7 1.8 2.0 1.7 1.8 1.8 1.8 1.9 1.2 1.8 1.8 1.5 1.6 1.5 1.8 1.1 2.0 1.8 1.6 1.2 0.3 0.8 1.6 2.0 1.9 1.1 1.1 2.1 1.3 2.1 2.0
High blood pressure 5.3 14.7 32.4 4.9 4.0 2.5 3.2 5.7 4.9 4.7 4.9 3.9 4.9 3.3 3.6 2.0 0.5 2.2 -0.5 4.9 2.4 4.5 2.6 3.9 3.5 2.8 2.7 2.5 4.8 3.1 5.7 5.0 2.7 1.7 4.5 2.2 3.0 1.4 2.5 2.4 2.6 5.5 0.8 4.1 5.2 4.8 4.7 4.2 4.3 4.7 4.8 4.6 4.8
Hayfever, allergic rhinitis or eczema 0.6 1.3 5.1 -0.5 0.3 1.4 -0.7 -1.4 -0.3 0.5 0.1 0.3 -0.5 0.5 0.9 1.1 2.3 0.7 -2.3 -2.2 1.4 -0.0 1.0 0.2 0.7 0.7 1.2 1.3 -0.1 1.0 -2.0 -0.7 1.4 1.4 0.7 1.8 1.1 0.9 1.3 1.4 0.6 -2.0 -1.2 -2.2 -0.6 -0.5 -0.4 -1.5 -0.7 0.1 -2.1 -0.2 -0.2
Multivitamins +/- minerals 0.2 0.2 0.8 0.4 -0.0 0.6 0.3 -0.6 -0.8 0.1 0.3 0.2 0.7 -0.2 0.3 0.4 0.5 0.6 -0.7 0.2 0.7 0.1 0.1 0.4 0.7 0.5 0.6 0.5 0.3 0.7 0.3 0.3 0.7 0.5 0.5 0.8 0.5 0.3 0.7 0.6 0.1 0.0 -0.3 0.1 -0.2 0.5 0.7 0.3 0.4 0.9 0.3 0.7 0.3
Stomach or abdominal pain in last month 0.2 0.2 2.0 -0.1 -0.1 -0.5 0.8 0.1 -0.3 -0.1 -0.6 -0.1 -0.4 -1.0 -0.3 -0.0 -0.5 0.0 0.7 0.2 -0.5 0.1 -0.5 -0.0 -0.4 0.1 -0.5 -0.5 -0.3 -0.5 -0.1 0.1 -0.5 -0.2 -0.7 -1.4 -0.5 -0.2 -0.7 -0.5 0.1 -0.3 -0.2 -0.2 -0.5 -0.1 -0.1 0.8 0.0 -0.4 0.3 -0.3 -0.2
Supplements: Glucosamine 1.4 1.8 4.8 0.6 1.6 1.8 0.3 0.1 1.2 0.7 0.4 1.9 1.0 -0.1 1.0 1.6 2.2 1.6 -2.1 -1.1 1.7 1.5 1.9 0.8 1.3 2.0 1.7 1.8 0.9 1.6 -0.4 0.2 1.6 2.1 1.1 1.6 1.6 1.3 1.5 1.8 1.8 -0.2 -1.7 -1.6 1.0 0.7 0.5 -0.3 0.6 1.0 -0.9 1.2 0.9
Diverticular disease/diverticulitis (self-reported) 0.4 0.5 1.4 -0.8 -0.5 -0.6 -0.5 -0.4 -0.9 -0.4 0.1 -0.3 -1.2 -0.4 -0.7 -0.7 -0.7 -0.7 0.5 -0.6 -0.6 -1.1 -0.6 -0.6 -0.7 -0.5 -0.6 -0.6 -0.8 -0.8 -1.1 -1.0 -0.7 -0.3 -1.0 -0.5 -0.7 -0.5 -0.4 -0.6 -0.6 -0.9 -0.5 -1.0 -1.0 -0.6 -0.8 -0.2 -0.4 -1.0 -0.6 -1.1 -0.9
Medication: Atenolol 1.2 1.5 9.6 1.2 1.4 1.0 0.8 1.5 0.7 1.2 1.6 2.2 1.2 3.1 1.1 0.7 0.8 0.8 -0.5 1.0 1.0 1.1 0.8 1.0 1.1 1.3 1.1 1.0 1.0 1.1 0.9 1.9 1.0 0.8 1.8 1.7 1.0 0.6 0.7 1.0 0.4 1.0 -0.9 0.8 1.4 1.5 1.2 0.8 1.5 1.2 0.9 1.3 1.2
Medication: Levothyroxine sodium 0.2 0.4 1.4 -0.0 -0.5 -0.8 -0.3 0.4 -0.6 -0.2 0.5 0.1 -0.1 0.3 -0.4 -0.9 -0.9 -0.5 1.2 0.7 -0.8 0.1 -1.1 -0.3 -0.5 -0.2 -0.7 -0.8 -0.4 -0.7 0.8 -0.0 -0.8 -1.0 -0.3 0.2 -0.7 -1.1 -0.6 -0.8 -0.8 0.7 0.7 0.9 0.1 0.0 -0.1 0.2 0.2 -0.5 0.7 -0.2 -0.1
Sitting height 3.2 23.0 46.0 -4.2 -6.1 -5.5 -3.1 -3.8 -4.2 -4.8 -3.3 -6.8 -4.4 -5.2 -5.4 -5.1 -5.2 -4.9 5.1 -1.4 -5.5 -5.4 -5.0 -4.4 -5.3 -5.8 -5.8 -5.6 -4.5 -5.5 -2.2 -4.3 -5.5 -5.7 -5.5 -4.7 -5.5 -4.8 -5.2 -5.5 -4.7 -1.6 5.3 3.1 -5.3 -4.7 -3.9 -3.1 -4.7 -5.1 -0.9 -5.0 -4.4
Chronic bronchitis/emphysema (father) 2.0 2.3 4.7 -1.9 -1.9 -1.7 -1.7 -1.9 -2.2 -1.4 -0.7 -1.3 -1.7 1.2 -1.5 -1.6 -1.1 -1.7 1.1 -1.0 -1.6 -1.9 -1.9 -1.7 -1.8 -1.6 -1.7 -1.7 -2.0 -1.7 -0.8 -1.7 -1.6 -1.5 -1.0 -0.5 -1.8 -0.8 -1.6 -1.7 -1.9 -1.3 0.5 -0.4 -1.8 -1.8 -1.8 -0.7 -1.3 -1.4 -1.2 -1.7 -1.9
High blood pressure (mother) 0.6 0.9 2.0 1.2 0.6 0.9 0.6 1.2 0.8 0.9 0.7 0.9 1.1 1.0 1.0 0.6 0.5 0.5 -0.6 1.1 0.9 1.2 0.6 0.8 1.1 0.6 0.9 0.9 1.4 1.0 1.0 1.0 1.1 0.4 1.3 1.1 1.0 0.2 1.3 0.9 0.4 1.3 1.2 0.7 1.0 1.2 1.2 0.2 0.2 1.4 1.0 1.1 1.2
Body mass index (BMI) 2.4 10.4 21.4 3.1 3.8 3.7 2.1 2.7 3.3 3.2 2.9 4.5 3.2 3.2 3.5 2.8 3.2 3.0 -3.2 1.0 3.7 3.7 3.3 3.2 3.6 3.9 3.8 3.7 3.3 3.7 1.1 2.6 3.7 3.4 3.5 4.6 3.7 2.9 3.5 3.7 2.6 2.6 -3.1 0.2 3.6 3.3 3.0 2.6 2.9 3.2 1.0 3.5 3.2
Impedance of leg (left) 0.2 0.7 5.8 0.9 0.6 -0.2 1.1 1.2 -0.1 0.8 0.8 -0.0 0.9 -0.4 0.5 0.4 -0.8 0.4 0.7 1.7 -0.2 0.3 0.5 0.7 0.3 -0.1 -0.1 -0.2 0.7 0.1 2.2 1.4 -0.2 0.1 0.3 -2.4 0.0 -0.2 -0.3 -0.2 0.6 0.7 0.9 0.9 0.5 1.0 0.9 1.3 0.9 0.8 1.7 0.6 0.7
Leg predicted mass (left) 0.3 1.5 3.7 -1.1 -1.5 -1.1 -1.0 -1.0 -0.2 -1.2 -0.3 -0.8 -1.3 -1.6 -1.6 -1.5 -0.8 -1.6 0.9 -1.1 -1.1 -1.1 -1.4 -1.2 -1.2 -0.8 -1.1 -1.0 -1.0 -1.2 -1.9 -1.6 -1.0 -1.4 -1.3 1.9 -1.2 -0.8 -1.1 -1.1 -1.7 0.8 1.0 1.7 -1.1 -1.2 -1.0 -1.2 -1.7 -1.6 -0.8 -1.3 -1.0
Trunk fat mass 0.7 2.9 9.9 1.9 1.9 1.5 1.6 1.9 2.0 1.7 2.1 2.3 2.0 1.2 1.7 1.0 0.8 1.1 -0.9 1.2 1.5 2.0 1.2 2.0 1.7 1.9 1.6 1.5 2.1 1.7 1.3 1.7 1.5 1.2 1.7 2.7 1.6 1.1 1.4 1.5 0.8 3.1 -0.9 1.9 1.9 2.0 1.9 1.9 1.5 1.7 1.4 2.0 1.9
Waist circumference 1.3 4.9 13.3 2.4 2.4 2.2 1.6 2.4 2.4 2.3 2.0 3.1 2.5 1.6 2.4 1.6 1.6 1.8 -1.5 1.3 2.2 2.9 1.8 2.2 2.4 2.9 2.3 2.2 2.6 2.4 1.4 2.1 2.2 1.9 2.1 3.7 2.3 1.6 2.0 2.2 1.4 3.2 -1.1 1.5 2.7 2.5 2.3 1.7 1.7 2.1 1.4 2.6 2.5
Number of incorrect matches in round 2.7 4.5 7.2 1.9 2.3 2.4 2.0 1.6 1.6 2.2 2.7 2.6 2.2 2.2 2.5 2.4 2.1 2.4 -2.0 0.9 2.4 2.2 2.3 2.3 2.3 2.4 2.4 2.3 2.1 2.4 1.1 1.9 2.5 2.3 2.6 1.3 2.4 1.8 2.4 2.4 2.2 0.5 -2.0 0.2 2.2 2.0 1.9 1.8 2.4 2.3 0.6 2.4 2.1
Past tobacco smoking 1.2 2.3 10.6 -1.6 -1.6 -1.1 -1.2 -1.8 -1.0 -1.1 -1.1 -3.3 -1.5 -1.2 -1.2 -0.7 -0.7 -0.9 0.6 -1.3 -1.1 -2.3 -1.2 -1.4 -1.3 -2.7 -1.3 -1.1 -1.4 -1.2 -1.4 -1.8 -1.2 -0.9 -1.5 -2.0 -1.2 -1.0 -0.9 -1.1 -0.7 -2.6 1.7 -1.3 -2.2 -1.9 -1.6 -1.0 -1.9 -0.8 -1.3 -1.7 -1.7
Alcohol usually taken with meals 0.3 0.5 3.6 1.0 0.8 0.4 0.6 0.8 0.5 0.7 -0.5 -0.3 0.8 -0.2 0.8 0.8 -0.0 1.3 0.1 1.1 0.3 0.6 0.2 0.6 0.6 0.4 0.3 0.4 0.8 0.5 0.4 1.5 0.3 0.4 0.1 -1.9 0.5 0.3 0.1 0.4 1.2 0.4 0.1 -0.8 0.5 0.9 0.8 0.1 0.8 0.6 1.1 0.7 0.8
Nervous feelings 0.9 1.6 5.2 -1.0 -1.4 -1.5 -0.1 -0.4 -0.8 -1.5 -1.4 -1.8 -0.9 -1.5 -1.3 -1.4 -1.3 -1.3 1.5 -0.1 -1.5 -1.1 -1.4 -1.0 -1.4 -1.6 -1.5 -1.5 -0.8 -1.4 -0.1 -0.9 -1.6 -1.4 -2.2 -2.3 -1.4 -0.8 -1.5 -1.5 -0.9 -0.1 1.5 0.3 -1.1 -1.2 -1.0 -0.7 -1.2 -1.3 -0.1 -1.1 -1.1
Frequency of tenseness / restlessness in last 2 weeks 1.3 2.1 6.1 1.6 1.1 0.9 1.8 2.3 1.5 1.4 1.4 1.4 1.9 2.0 1.4 0.6 0.4 0.7 -0.2 1.7 0.9 2.1 0.7 1.6 1.2 1.2 1.0 0.9 1.8 1.2 2.2 1.6 0.8 0.5 1.1 1.0 1.1 0.5 1.0 0.9 0.5 2.5 0.1 2.1 1.8 1.6 1.7 2.2 1.6 1.4 1.5 1.8 1.6
Hearing difficulty/problems with background noise 0.5 0.8 3.4 -1.1 -0.6 -0.8 -0.7 -1.1 -0.7 -0.9 -1.9 -0.2 -1.2 0.1 -1.2 -0.6 -0.2 -0.7 0.5 -0.9 -0.8 -0.7 -1.1 -0.8 -1.0 -0.6 -0.7 -0.8 -1.0 -1.0 -1.3 -1.1 -0.8 -0.2 -1.5 -0.3 -0.9 0.0 -0.8 -0.8 -0.5 -0.7 -0.6 -1.1 -1.0 -0.9 -1.2 -0.9 -0.4 -1.3 -0.9 -1.1 -1.0
Hair/balding pattern: Pattern 2 1.1 1.4 4.2 1.3 1.4 0.8 1.0 1.6 1.7 1.6 1.3 1.1 1.3 2.0 1.3 0.9 0.5 0.7 -0.4 1.3 0.7 1.1 1.2 1.5 1.0 0.8 0.8 0.8 1.4 0.9 1.3 1.6 0.8 0.8 1.6 0.1 0.9 1.7 0.8 0.8 1.2 1.0 -0.4 0.3 1.4 1.2 1.1 1.4 1.5 1.5 1.1 1.2 1.3
Had menopause 0.7 0.8 3.2 0.6 1.7 0.9 0.6 0.9 0.4 0.2 0.1 1.8 0.9 0.6 0.8 1.0 1.2 1.1 -1.0 -0.0 0.9 1.0 0.7 0.6 0.8 1.4 1.0 0.9 0.7 0.9 0.4 0.5 1.0 1.5 0.7 -0.1 0.9 1.5 0.8 0.9 1.4 -0.2 -1.2 -0.8 1.1 0.9 0.4 0.0 1.3 0.8 -0.1 1.0 0.7
Had other major operations 0.2 0.2 1.8 -0.4 0.3 0.0 -0.0 -0.1 0.6 0.4 1.1 0.8 -0.6 0.7 -0.1 -0.1 0.4 -0.2 -0.4 -0.9 -0.0 0.0 0.2 -0.3 -0.3 0.4 0.1 0.1 -0.0 -0.2 -0.7 -0.5 0.1 0.1 0.1 1.4 -0.1 0.2 -0.0 0.0 -0.3 -0.2 -0.4 0.7 0.1 -0.4 -0.5 -0.0 -0.1 -0.1 -1.0 -0.4 -0.1
Forced vital capacity (FVC) 1.6 6.3 10.7 -2.6 -3.2 -2.7 -1.8 -2.7 -2.7 -2.2 -2.2 -3.3 -2.7 -1.3 -2.8 -2.3 -2.3 -2.1 2.3 -1.1 -2.7 -2.9 -2.8 -2.6 -2.8 -2.4 -2.9 -2.8 -2.7 -2.8 -1.7 -2.7 -2.5 -2.9 -2.6 -2.4 -2.8 -2.2 -2.0 -2.7 -2.3 -2.0 1.9 0.1 -3.1 -2.8 -2.4 -2.1 -2.8 -3.2 -1.2 -2.8 -2.7
Heel bone mineral density (BMD) T-score, automated (right) 0.4 1.0 3.2 0.4 0.7 1.4 -0.0 -0.7 0.0 0.5 -0.1 0.4 0.4 1.4 0.8 1.3 1.3 1.5 -1.6 -0.3 1.4 0.1 1.4 0.3 1.2 0.6 1.4 1.4 0.3 1.2 -0.9 0.3 1.5 1.4 0.7 0.2 1.2 0.9 1.7 1.4 1.0 -1.3 -1.5 -1.8 0.1 0.5 0.4 -0.4 0.1 0.6 -0.6 0.5 0.4
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 3.8 0.5 -0.5 -0.6 1.0 0.7 0.1 0.2 -0.2 -0.7 0.6 -1.6 -0.5 -0.4 -1.1 -0.8 1.2 1.4 -0.6 -0.2 -0.4 0.3 -0.2 -0.7 -0.6 -0.6 0.4 -0.3 1.4 0.9 -0.4 -0.8 -0.1 -0.6 -0.5 -0.3 -0.7 -0.6 -0.7 1.2 1.9 1.9 0.0 0.5 0.7 1.6 -0.1 0.6 1.5 0.2 0.3
Qualifications: None of the above 0.5 1.0 4.0 1.2 1.1 0.3 1.2 1.5 0.9 1.2 1.1 0.8 1.1 1.9 0.9 0.7 -0.1 0.7 0.3 1.7 0.3 0.8 0.4 0.9 0.7 0.6 0.4 0.3 0.9 0.5 2.0 2.0 0.2 0.3 0.8 0.2 0.5 1.3 0.2 0.3 0.8 0.6 -0.1 -0.1 1.1 1.2 1.1 0.7 1.5 1.1 1.6 1.1 1.0
Financial difficulties in last 2 years 0.7 0.9 6.9 0.6 0.5 1.0 0.2 0.6 0.8 0.9 1.5 1.9 0.7 1.4 1.0 0.4 0.9 0.3 -1.0 -0.0 1.0 1.2 1.1 0.4 0.9 1.5 1.0 1.0 0.7 1.0 -0.1 0.5 1.1 0.6 1.3 2.6 0.9 0.2 1.1 1.0 -0.1 0.9 -0.0 0.9 1.0 0.7 0.7 0.7 0.2 0.8 -0.1 0.8 0.8
Mouth/teeth dental problems 0.3 0.5 2.3 0.0 0.7 0.7 0.6 -0.6 0.1 0.7 0.1 0.4 0.0 0.0 0.2 1.0 1.0 1.1 -1.2 -0.5 0.7 -0.1 0.9 0.2 0.5 0.7 0.7 0.7 -0.1 0.6 -0.6 -0.7 0.8 1.1 0.5 -0.3 0.5 1.3 1.1 0.7 0.9 -1.3 -1.4 -1.5 -0.0 0.1 -0.0 -0.3 0.5 0.4 -0.6 0.2 0.1
Heart attack 5.5 7.0 11.2 2.9 3.3 2.5 3.4 2.9 2.9 3.1 2.0 2.9 3.0 2.5 3.0 2.7 1.8 2.9 -1.7 2.0 2.5 3.2 2.6 2.9 2.8 2.8 2.6 2.5 2.8 2.7 1.9 2.8 2.5 2.6 2.8 0.8 2.6 2.5 2.5 2.5 3.2 2.0 -2.1 1.0 3.2 2.9 2.8 2.5 3.0 2.5 1.9 3.1 3.0
Allergy 0.6 1.5 7.1 1.4 0.7 -0.2 1.7 2.0 1.4 0.4 1.2 0.7 1.3 0.1 0.2 -0.0 -1.3 0.2 1.2 2.3 -0.2 1.2 0.1 1.1 0.4 0.5 -0.1 -0.2 1.1 0.2 2.1 1.3 -0.3 -0.4 0.6 -1.2 0.1 0.4 -0.1 -0.2 0.6 2.4 0.1 2.7 1.4 1.4 1.4 2.5 1.6 0.7 2.3 1.1 1.3
Pain all over the body in last month 3.3 3.5 5.8 2.0 2.3 2.1 1.6 2.0 2.2 1.8 1.5 2.4 2.0 1.9 2.0 2.1 1.6 1.9 -1.6 0.9 2.1 2.2 1.6 1.9 2.1 2.2 2.1 2.1 2.0 2.1 0.9 1.3 2.0 1.8 2.2 1.1 2.1 2.1 2.3 2.1 1.8 1.3 -1.3 -0.0 2.4 2.0 1.9 1.2 2.0 1.9 0.9 2.0 2.1
Diabetes (self-reported) 0.8 1.3 3.0 1.1 1.1 1.2 0.5 1.1 0.6 1.1 1.7 1.7 1.5 -0.0 1.5 1.1 1.0 0.9 -0.9 0.3 1.3 1.5 0.5 1.2 1.3 1.7 1.3 1.2 1.4 1.4 1.1 0.8 1.2 1.0 1.0 1.4 1.3 0.1 1.0 1.2 0.6 1.6 -0.5 0.6 1.4 1.3 1.1 0.8 0.6 1.1 0.6 1.5 1.1
Hayfever/allergic rhinitis (self-reported) 0.9 1.1 5.5 -0.5 -0.1 1.1 -1.1 -1.5 -1.4 -0.2 -0.5 0.2 -0.6 -0.7 0.5 0.8 1.7 0.9 -1.9 -1.6 1.1 0.0 0.5 -0.3 0.6 1.1 1.0 1.0 -0.4 0.7 -1.9 -0.3 1.2 1.1 0.4 0.8 0.8 0.2 0.9 1.1 0.6 -2.3 -1.5 -2.3 -0.8 -0.5 -0.4 -1.9 -0.9 -0.6 -1.7 -0.2 -0.4
Medication: Ramipril 4.0 5.1 9.8 2.4 2.4 2.0 2.0 2.9 1.9 2.1 3.1 3.0 2.8 2.6 2.7 1.8 1.4 1.9 -1.3 1.7 2.0 2.8 1.9 2.6 2.3 2.6 2.2 2.0 2.8 2.3 2.5 1.9 2.1 1.6 2.5 2.0 2.3 1.5 2.3 2.0 1.6 2.3 -0.7 2.2 2.6 2.6 2.4 2.5 2.2 2.4 1.7 2.8 2.5
Medication: Simvastatin 9.8 14.4 23.5 4.3 4.6 3.4 4.2 4.6 4.3 4.2 2.9 4.8 4.3 3.0 3.9 3.4 2.5 3.7 -2.1 3.1 3.4 4.7 3.3 4.4 3.9 4.3 3.6 3.5 4.3 3.8 3.4 4.1 3.4 3.3 3.9 2.1 3.7 3.6 3.4 3.4 3.6 3.9 -2.6 1.3 4.7 4.5 4.1 4.1 4.7 4.2 3.0 4.4 4.3
Fluid intelligence score 0.1 0.2 0.6 0.6 -0.0 0.4 0.3 0.4 0.3 0.8 0.2 -0.2 0.7 0.0 0.7 0.3 0.1 0.2 -0.2 0.7 0.4 0.5 0.4 0.5 0.5 -0.1 0.3 0.4 0.6 0.5 0.7 0.6 0.5 -0.1 0.8 -0.3 0.4 -0.1 0.5 0.4 0.1 0.6 0.6 0.5 0.5 0.6 0.8 -0.2 0.5 0.7 0.8 0.6 0.6
Illnesses of siblings 4.1 5.8 18.5 -3.1 -2.2 -0.9 -2.2 -3.9 -3.0 -3.3 -3.3 -2.2 -3.1 -3.1 -2.3 -1.0 0.6 -1.1 -0.6 -3.8 -0.8 -2.5 -1.1 -2.2 -1.8 -1.3 -1.0 -0.9 -2.9 -1.4 -4.3 -3.3 -0.8 -0.3 -2.6 -0.9 -1.3 -0.4 -0.9 -0.9 -1.0 -3.4 -1.7 -2.8 -3.0 -3.1 -3.0 -3.1 -2.5 -3.0 -3.8 -2.7 -3.0
Neuroticism score 0.2 0.3 2.6 0.5 -0.2 -0.3 0.9 0.9 0.3 0.2 -0.2 -0.4 0.7 -1.6 -0.2 -0.1 -0.7 -0.4 0.7 0.9 -0.3 0.3 -0.5 0.4 0.0 -0.3 -0.3 -0.3 0.4 -0.1 1.0 0.6 -0.5 -0.6 -0.7 -0.4 -0.2 0.1 -0.4 -0.3 -0.3 1.6 0.5 0.9 0.4 0.4 0.5 0.4 0.1 0.0 1.1 0.5 0.3
Weight 0.2 1.2 10.6 0.9 0.9 1.1 0.6 0.6 1.5 0.9 1.5 1.6 0.9 -0.1 0.7 0.5 0.9 0.6 -0.9 -0.1 1.1 1.2 0.9 0.9 1.1 1.6 1.1 1.1 1.1 1.1 -0.4 0.4 1.2 0.8 0.8 3.3 1.1 0.7 1.0 1.1 0.3 2.0 -0.6 1.7 1.0 1.0 1.0 0.5 0.2 0.5 0.2 1.0 1.1
Impedance of arm (right) 0.9 4.3 15.8 -1.2 -2.3 -2.8 -0.5 -0.7 -1.8 -1.7 -0.9 -2.7 -1.3 -2.4 -1.8 -2.0 -3.1 -2.2 3.1 0.9 -2.8 -1.9 -2.4 -1.3 -2.3 -2.7 -2.8 -2.8 -1.3 -2.5 1.0 -0.7 -2.8 -2.8 -2.0 -4.0 -2.5 -2.1 -2.7 -2.8 -1.8 0.2 2.3 1.5 -1.5 -1.4 -1.1 -0.2 -0.8 -1.7 1.1 -1.7 -1.5
Arm fat percentage (right) 1.6 6.2 13.1 2.6 2.8 2.5 1.9 2.4 2.6 2.4 2.3 3.6 2.7 2.3 2.7 1.9 1.9 2.0 -1.9 1.3 2.5 3.0 2.2 2.7 2.7 2.9 2.7 2.5 2.8 2.7 1.5 2.4 2.5 2.3 2.8 3.6 2.6 1.9 2.3 2.5 1.6 3.1 -2.1 0.9 3.0 2.8 2.5 2.5 2.5 2.5 1.4 2.8 2.6
Trunk fat-free mass 0.5 2.8 8.8 -1.8 -1.9 -1.1 -1.6 -2.0 -0.8 -1.7 -1.1 -1.5 -2.0 -2.7 -2.0 -1.4 -0.4 -1.5 0.5 -2.2 -1.1 -1.9 -1.2 -1.9 -1.5 -0.9 -1.2 -1.0 -1.7 -1.4 -3.0 -2.3 -1.0 -1.3 -1.8 1.6 -1.3 -0.9 -1.1 -1.1 -1.6 -0.3 1.3 1.1 -1.9 -1.9 -1.7 -2.4 -2.9 -2.3 -1.8 -1.9 -1.5
Hip circumference 0.3 1.4 5.6 1.2 1.2 1.1 1.0 1.2 1.9 1.1 1.5 1.6 1.1 1.4 1.1 0.5 0.7 0.9 -0.7 0.4 1.1 1.7 1.0 1.2 1.1 1.6 1.1 1.1 1.4 1.1 0.2 0.6 1.1 0.8 1.1 2.2 1.1 0.9 1.1 1.1 0.8 2.4 -1.1 1.6 1.5 1.1 1.1 1.3 0.9 0.6 0.5 1.2 1.3
Time employed in main current job 0.2 0.2 2.1 0.2 0.4 0.2 0.3 0.3 1.0 0.1 0.7 0.3 -0.0 -0.7 0.3 0.2 0.5 0.3 -0.4 -0.4 0.2 0.6 0.8 0.4 0.1 0.6 0.2 0.3 0.3 0.2 -0.3 -0.1 0.1 0.3 0.1 -0.4 0.2 1.4 0.0 0.2 0.7 0.1 -1.1 0.5 0.5 -0.0 0.0 0.4 0.5 -0.4 -0.2 0.1 0.3
Alcohol intake versus 10 years previously 0.8 1.2 4.3 1.4 0.3 0.4 0.9 1.4 0.1 1.2 1.2 0.7 1.5 0.2 1.3 0.1 -0.7 0.2 0.3 1.8 0.5 0.6 0.3 1.3 1.0 0.3 0.5 0.4 1.1 0.8 1.9 1.4 0.5 -0.4 0.9 1.8 0.6 -0.4 0.5 0.4 -0.8 1.9 0.8 2.1 1.0 1.5 1.7 1.6 1.0 1.4 2.0 1.3 1.1
Father’s age at death 0.1 0.2 2.7 -0.3 -0.2 -0.1 0.0 -0.7 0.2 -0.4 -0.6 -0.5 -0.2 -1.7 -0.5 -0.3 -0.1 -0.1 -0.1 -0.6 -0.1 -0.4 0.3 -0.5 -0.2 -0.4 -0.1 -0.1 -0.6 -0.1 -0.6 -0.9 -0.1 -0.0 -0.7 -0.7 -0.2 0.1 0.1 -0.1 0.1 -0.4 -0.7 0.3 -0.1 -0.3 -0.2 0.1 0.5 -0.2 -0.3 -0.2 -0.2
Worrier / anxious feelings 0.9 1.8 3.5 1.5 1.6 1.4 0.8 1.6 1.2 1.4 1.6 1.8 1.6 0.2 1.6 1.2 0.9 1.1 -1.1 0.9 1.4 1.8 1.4 1.5 1.5 1.5 1.4 1.4 1.9 1.5 1.0 1.5 1.3 1.1 0.9 1.1 1.5 0.8 1.4 1.4 1.2 1.4 -0.5 0.4 1.6 1.6 1.4 0.2 1.4 1.3 0.9 1.6 1.5
Frequency of tiredness / lethargy in last 2 weeks 2.2 3.6 8.9 2.0 2.2 1.7 2.7 2.1 1.9 2.0 1.7 2.6 2.4 0.2 1.7 1.6 1.2 1.6 -1.1 1.4 1.7 2.0 1.3 2.1 2.0 2.2 1.9 1.7 2.0 2.0 1.7 2.3 1.7 1.8 1.9 2.2 1.7 0.9 1.5 1.7 1.3 2.4 -0.8 1.9 2.1 2.4 2.2 3.0 1.7 2.3 1.5 2.3 2.0
Falls in the last year 1.7 2.3 4.6 1.4 1.9 1.9 1.6 1.1 1.9 1.3 0.9 1.4 1.2 0.6 1.5 1.8 1.6 1.9 -1.9 0.3 1.9 1.6 2.1 1.5 1.8 1.7 1.9 1.9 1.5 1.8 0.0 1.2 1.9 2.0 1.6 0.9 1.8 1.0 1.7 1.9 2.0 0.2 -0.7 0.6 1.0 1.4 1.4 1.5 0.7 1.6 0.2 1.4 1.6
Hair/balding pattern: Pattern 3 1.0 1.5 3.8 -1.1 -1.4 -1.1 -1.2 -1.4 -1.9 -1.4 -1.2 -1.0 -1.3 -1.9 -1.4 -1.3 -0.8 -1.2 0.9 -0.6 -1.0 -1.2 -1.3 -1.5 -1.1 -1.0 -1.0 -1.1 -1.5 -1.2 -1.1 -0.7 -1.1 -1.2 -1.4 0.4 -1.2 -1.6 -1.3 -1.1 -1.8 -0.8 1.0 -0.6 -1.3 -0.9 -0.9 -1.7 -1.0 -1.3 -0.4 -1.3 -1.3
Number of live births 1.5 2.1 4.6 1.6 1.8 1.6 1.6 1.7 2.1 1.8 -0.7 1.6 1.7 1.0 1.6 1.7 1.3 1.6 -1.2 0.9 1.5 2.0 1.8 1.2 1.6 1.3 1.6 1.6 1.7 1.6 1.0 1.2 1.5 1.4 1.1 1.5 1.7 1.2 1.8 1.6 1.6 0.9 0.6 -0.1 1.5 1.5 1.3 0.4 0.4 1.6 0.7 1.6 1.7
Forced expiratory volume in 1-second (FEV1) 1.1 3.7 6.5 -2.2 -2.5 -1.9 -1.3 -2.5 -2.0 -1.7 -1.7 -2.4 -2.2 -1.1 -2.1 -1.8 -1.4 -1.5 1.4 -1.2 -1.9 -2.3 -2.0 -2.0 -2.1 -1.5 -2.0 -1.9 -2.3 -2.0 -1.8 -2.3 -1.7 -2.1 -2.1 -1.6 -2.0 -1.3 -1.1 -1.9 -1.7 -2.0 0.9 -0.3 -2.5 -2.3 -2.0 -1.6 -2.4 -2.5 -1.4 -2.2 -2.2
Pulse rate 0.2 0.4 1.4 -0.6 -0.7 -0.6 -0.2 -0.4 -0.7 -0.7 -1.1 -1.2 -0.5 -1.1 -0.7 -0.3 -0.3 -0.6 0.4 -0.3 -0.6 -0.7 -0.4 -0.3 -0.6 -1.0 -0.6 -0.6 -0.6 -0.6 -0.1 -0.8 -0.6 -0.3 -0.5 -0.9 -0.6 -1.1 -0.6 -0.6 -0.4 -0.5 1.1 0.1 -0.8 -0.7 -0.5 -0.1 -0.6 -0.1 -0.3 -0.6 -0.6
Happiness 0.4 0.4 3.0 -0.3 -0.4 -1.0 0.2 0.1 -0.3 -0.8 -1.3 -0.5 -0.1 -0.3 -0.7 -0.6 -0.9 -0.5 1.1 0.5 -1.0 -0.4 -0.8 -0.3 -0.8 -0.4 -0.9 -1.0 -0.5 -0.8 0.4 -0.5 -1.1 -0.6 -0.5 -1.7 -0.9 -0.3 -0.9 -1.0 -0.2 -0.0 0.6 0.1 -0.1 -0.3 -0.3 -0.1 0.3 -0.5 0.4 -0.2 -0.4
Noisy workplace 1.1 1.4 3.8 -1.1 -1.3 -1.5 -0.8 -0.6 -1.3 -1.6 -0.3 -0.7 -1.2 -0.2 -1.1 -1.3 -1.4 -1.6 1.4 -0.3 -1.5 -0.8 -1.9 -1.0 -1.4 -0.8 -1.4 -1.5 -0.8 -1.5 -0.5 -1.0 -1.6 -1.3 -1.4 -0.9 -1.4 -0.9 -1.9 -1.5 -1.5 0.3 1.1 0.8 -0.9 -1.0 -1.1 -0.3 -0.7 -1.2 -0.2 -1.2 -1.2
Qualifications: A levels/AS levels or equivalent 0.7 1.6 5.5 -1.4 -1.5 -0.3 -1.7 -2.3 -1.1 -1.4 -2.0 -1.8 -1.2 -1.1 -0.9 -0.6 0.3 -0.9 -0.4 -1.8 -0.3 -1.4 -0.8 -1.3 -0.8 -1.1 -0.5 -0.4 -1.4 -0.6 -2.0 -2.3 -0.4 -0.5 -1.4 0.5 -0.6 -0.3 0.0 -0.3 -0.8 -2.0 0.3 -1.3 -1.6 -1.7 -1.4 -2.1 -1.9 -1.1 -1.8 -1.2 -1.3
Serious illness, injury or assault of a close relative in last 2 years 2.5 2.9 17.9 0.9 2.0 2.1 0.8 0.7 1.4 1.2 0.2 2.5 0.7 0.9 1.6 1.9 2.4 1.7 -2.4 -0.9 2.1 1.7 1.8 1.5 1.7 2.2 2.1 2.1 0.9 1.8 -1.1 0.3 2.0 2.4 1.4 2.0 1.9 2.5 1.9 2.1 1.7 -0.0 -4.2 -1.9 1.2 1.0 0.7 0.1 2.0 0.8 -1.0 1.1 1.1
Mouth/teeth dental problems: Dentures 2.2 3.7 9.0 2.4 2.1 1.9 1.0 2.6 1.8 2.0 2.4 2.2 2.2 0.8 2.5 1.7 1.3 1.9 -1.0 1.5 1.9 2.3 1.9 2.1 2.2 2.0 1.9 1.9 2.5 2.0 1.4 3.0 1.7 1.7 1.8 1.1 2.1 1.4 1.4 1.9 2.0 1.8 -0.3 1.3 2.2 2.4 2.2 1.8 1.3 1.9 1.8 2.3 2.3
Asthma 0.2 0.4 1.9 -0.5 -0.7 -0.5 -0.7 -0.3 -0.9 -0.0 -1.2 -1.0 -0.5 -0.4 -0.3 -0.3 -0.4 -0.3 0.5 -0.0 -0.5 -0.9 -0.3 -0.6 -0.5 -1.1 -0.5 -0.6 -0.4 -0.5 -0.2 -0.2 -0.5 -0.4 -0.9 -1.0 -0.5 -1.4 -0.5 -0.5 -0.7 -0.7 1.1 -1.0 -0.6 -0.5 -0.5 -0.7 -0.8 -0.1 -0.1 -0.6 -0.6
Medication: Ibuprofen (e.g. Nurofen) 1.8 2.3 4.4 1.7 2.0 1.5 1.9 2.0 1.8 2.1 1.2 1.5 1.8 -0.2 1.6 1.7 1.1 1.6 -1.1 1.1 1.5 1.5 1.6 1.5 1.7 1.4 1.5 1.5 1.9 1.6 1.1 1.7 1.5 1.6 1.2 0.2 1.6 0.5 1.3 1.5 1.8 1.1 0.8 0.4 1.5 1.9 1.7 1.5 1.1 2.1 1.2 1.7 1.7
Medication: Cholesterol lowering 7.1 11.0 23.0 4.1 3.8 2.4 3.9 4.8 3.9 3.7 3.2 4.0 4.0 2.5 3.0 2.4 1.1 2.7 -0.8 3.8 2.4 4.0 2.1 3.8 3.2 3.1 2.6 2.5 3.9 2.9 3.8 3.8 2.5 2.3 3.4 1.2 2.8 2.2 2.4 2.4 2.9 4.5 -1.3 2.3 4.2 4.3 4.0 4.0 4.2 3.8 3.8 4.0 4.1
Depression (self-reported) 0.5 0.7 3.9 0.8 -0.0 -0.2 0.7 1.4 0.7 0.1 0.6 0.7 0.7 0.6 -0.0 -0.5 -0.9 -0.4 1.0 1.5 -0.3 1.1 -0.5 0.4 0.1 0.0 -0.2 -0.2 0.6 -0.0 1.4 0.7 -0.1 -0.7 0.3 0.5 -0.1 -0.5 -0.0 -0.2 -0.7 2.0 0.6 1.7 1.0 0.9 0.9 1.6 1.0 0.7 1.4 0.6 0.8
Medication: Lansoprazole 2.4 2.8 7.8 -0.9 -1.7 -2.3 -0.9 0.2 -1.7 -1.6 -0.8 -1.4 -0.6 -0.1 -1.4 -2.3 -2.7 -1.9 2.8 1.0 -2.3 -1.4 -2.7 -1.2 -1.8 -2.1 -2.2 -2.3 -1.1 -2.0 1.3 -0.3 -2.2 -2.4 -1.1 -1.4 -2.1 -2.3 -2.4 -2.3 -2.2 1.0 2.0 1.5 -0.8 -0.7 -0.8 0.5 -0.4 -0.6 1.1 -1.0 -1.1
Prospective memory result 0.7 0.9 3.1 -0.1 -0.8 -1.3 -0.5 0.7 -0.8 -0.7 0.2 -0.6 -0.0 -0.4 -0.9 -0.9 -1.8 -1.0 1.7 1.2 -1.3 -0.7 -1.5 -0.2 -0.9 -0.8 -1.3 -1.3 -0.3 -1.0 1.0 0.2 -1.3 -1.4 -0.7 -1.2 -1.1 -0.8 -1.1 -1.3 -1.0 0.7 1.0 1.2 -0.1 -0.1 0.0 0.9 -0.0 -0.2 1.3 -0.2 -0.3
Lung cancer (father) 0.1 0.1 0.8 -0.2 -0.1 0.2 0.5 -0.6 -0.4 -0.2 -0.1 0.0 -0.4 -0.8 0.0 0.2 0.5 0.5 -0.4 -0.4 0.2 -0.4 -0.2 -0.0 0.1 0.3 0.2 0.2 -0.4 0.1 -0.6 -0.3 0.4 0.3 0.2 -0.3 0.1 -0.5 0.3 0.2 0.1 -0.7 -0.9 -0.1 -0.3 -0.1 -0.0 0.3 -0.2 -0.3 -0.5 -0.3 -0.1
Illnesses of mother 1.3 1.6 2.7 -1.4 -1.2 -1.6 -0.7 -0.6 -0.8 -1.5 -1.4 -1.2 -1.4 -0.8 -1.5 -1.4 -1.3 -1.2 1.4 -0.8 -1.6 -1.1 -1.3 -1.1 -1.7 -1.4 -1.6 -1.5 -1.3 -1.6 -0.7 -1.4 -1.6 -1.3 -1.6 -1.6 -1.6 -0.5 -1.5 -1.6 -1.1 -0.3 0.3 -0.2 -1.2 -1.3 -1.4 -0.7 -0.3 -1.6 -0.7 -1.5 -1.4
Forced expiratory volume in 1-second (FEV1), Best measure 0.3 0.9 3.1 -1.1 -1.3 -0.9 -0.1 -1.5 -0.9 -0.5 -0.9 -1.5 -1.1 -0.7 -1.2 -0.7 -0.8 -0.5 0.6 -0.6 -0.9 -1.2 -0.9 -0.8 -1.0 -0.6 -1.0 -0.9 -1.2 -1.0 -1.0 -1.1 -0.8 -1.0 -1.0 -1.7 -1.0 -0.2 -0.4 -0.9 -0.4 -1.3 -0.2 -0.1 -1.4 -1.2 -0.9 -0.6 -0.9 -1.4 -0.8 -1.1 -1.1
Pulse wave Arterial Stiffness index 1.2 1.4 3.5 1.1 1.5 1.2 1.0 1.0 1.5 1.9 0.7 0.8 1.0 -0.2 1.2 1.4 1.2 1.6 -1.2 0.5 1.2 1.2 1.6 1.2 1.2 0.9 1.2 1.3 1.3 1.2 0.3 1.0 1.2 1.7 1.4 -0.5 1.2 1.8 1.0 1.2 1.9 0.5 -1.0 0.1 0.9 1.0 1.0 0.4 1.5 1.2 0.4 1.0 1.3
Impedance of arm (left) 0.4 2.1 12.1 -0.6 -1.4 -2.0 0.1 -0.2 -0.9 -0.8 -0.3 -1.9 -0.7 -2.0 -1.1 -1.3 -2.4 -1.4 2.3 1.0 -2.0 -1.0 -1.5 -0.6 -1.5 -1.9 -2.0 -2.0 -0.6 -1.7 1.1 -0.3 -1.9 -1.9 -1.3 -3.5 -1.7 -1.5 -1.8 -2.0 -0.9 0.3 1.6 1.5 -0.9 -0.7 -0.5 0.3 -0.2 -1.0 1.1 -1.0 -0.7
Arm fat mass (right) 1.0 3.9 12.7 1.9 2.2 2.1 1.4 1.7 2.1 1.9 1.9 2.9 2.1 1.5 2.1 1.5 1.8 1.6 -1.7 0.6 2.1 2.4 1.8 2.1 2.2 2.5 2.2 2.1 2.2 2.2 0.6 1.6 2.1 1.9 2.0 3.6 2.2 1.7 2.0 2.1 1.2 2.7 -1.8 1.0 2.2 2.1 1.9 1.8 1.7 1.8 0.8 2.2 2.0
Trunk predicted mass 0.5 2.6 8.8 -1.7 -1.9 -1.0 -1.6 -2.0 -0.8 -1.7 -1.1 -1.4 -1.9 -2.7 -2.0 -1.4 -0.4 -1.4 0.4 -2.1 -1.0 -1.8 -1.2 -1.9 -1.4 -0.8 -1.1 -1.0 -1.6 -1.3 -3.0 -2.3 -0.9 -1.2 -1.8 1.6 -1.2 -0.8 -1.0 -1.0 -1.5 -0.3 1.2 1.0 -1.9 -1.8 -1.6 -2.4 -2.8 -2.2 -1.8 -1.8 -1.5
Standing height 2.0 20.0 48.0 -4.1 -5.4 -4.9 -2.9 -4.1 -3.4 -4.4 -2.8 -5.6 -4.5 -6.9 -5.5 -4.5 -4.3 -4.6 4.3 -2.2 -4.9 -5.0 -4.6 -4.4 -4.9 -4.5 -5.1 -4.9 -4.2 -5.0 -3.2 -4.4 -4.7 -5.0 -5.3 -2.5 -5.0 -4.0 -4.8 -4.9 -4.3 -0.9 4.7 3.2 -5.1 -4.5 -3.9 -4.1 -5.2 -5.3 -1.5 -4.9 -4.1
Length of working week for main job 0.1 0.1 1.3 0.1 0.6 0.1 0.8 0.1 0.1 0.3 0.2 1.1 0.1 -0.3 -0.1 0.2 0.2 -0.1 -0.3 -0.1 0.1 0.1 0.4 0.2 0.1 0.5 0.2 0.2 -0.1 0.1 0.1 -0.0 -0.0 0.4 0.0 0.4 0.1 1.0 0.1 0.1 -0.1 0.5 -0.4 -0.3 0.5 0.4 0.1 0.4 0.7 0.1 -0.1 0.2 0.2
Exposure to tobacco smoke at home 2.5 2.8 5.6 1.6 2.0 1.8 1.9 1.8 1.0 1.8 1.1 2.1 1.8 1.7 1.8 1.6 1.3 1.9 -1.6 0.9 1.8 2.1 1.4 1.8 1.8 2.0 1.9 1.8 1.7 1.9 1.3 1.5 1.7 1.9 1.4 0.8 1.8 1.8 1.8 1.8 1.8 1.1 -2.1 0.1 2.0 1.8 1.5 1.6 2.4 1.6 0.8 2.0 1.7
Breastfed as a baby 0.2 0.3 1.7 -0.8 -0.2 -0.1 0.3 -0.6 -0.5 -0.3 -1.1 -0.2 -0.6 0.2 -0.2 -0.4 0.3 0.0 -0.4 -1.1 -0.1 -0.6 0.0 -0.6 -0.4 -0.3 -0.1 -0.1 -0.7 -0.3 -1.1 -0.8 -0.1 0.2 -0.1 -0.2 -0.2 0.5 -0.0 -0.1 0.1 -1.3 -1.0 -0.4 -0.4 -0.7 -0.8 -0.3 0.2 -0.5 -1.1 -0.5 -0.6
Tense / ‘highly strung’ 0.5 0.9 3.2 0.9 0.7 1.0 1.8 1.4 1.2 0.6 0.2 0.3 1.3 -0.3 1.0 0.7 0.7 0.8 -0.8 0.4 1.0 1.2 0.9 1.3 1.0 0.6 0.9 1.0 1.3 1.1 0.8 1.0 0.9 0.7 0.5 0.8 1.0 0.7 0.8 1.0 0.7 1.4 -0.3 0.7 0.9 0.8 1.0 1.5 0.8 1.3 0.5 1.2 1.0
Seen doctor (GP) for nerves, anxiety, tension or depression 1.0 1.6 3.1 1.5 0.7 1.2 1.5 1.0 0.5 1.1 1.5 1.4 1.7 1.1 1.2 1.2 0.5 1.0 -0.6 1.4 1.3 1.4 0.6 1.5 1.5 1.0 1.3 1.2 1.3 1.4 1.1 1.6 1.3 0.5 1.4 1.4 1.3 0.1 1.3 1.2 0.2 1.7 -0.8 1.3 1.5 1.6 1.7 1.3 1.2 1.5 1.3 1.7 1.4
Hair/balding pattern: Pattern 4 0.5 1.3 3.4 1.3 0.5 1.1 0.9 1.2 1.4 1.3 1.8 0.6 1.4 -0.1 1.2 0.7 0.6 0.9 -0.6 1.1 1.1 0.9 0.6 1.2 1.2 0.9 1.1 1.1 1.5 1.2 1.0 1.2 1.2 0.5 1.5 1.0 1.2 0.1 1.3 1.1 0.6 1.6 -0.4 1.8 1.5 1.2 1.4 1.8 0.6 1.5 1.0 1.4 1.4
Birth weight of first child 0.3 0.6 1.9 -1.1 -0.6 -0.3 -0.1 -1.3 -0.7 -0.9 -1.3 -1.0 -0.9 -0.6 -0.9 -0.5 -0.2 -0.5 -0.2 -1.2 -0.3 -1.1 -0.2 -1.1 -0.6 -0.7 -0.4 -0.3 -0.9 -0.5 -1.0 -1.2 -0.3 -0.0 -0.5 0.0 -0.5 -0.9 -0.2 -0.3 -0.3 -1.4 0.6 -0.7 -1.2 -1.0 -1.0 -0.8 -1.0 -0.6 -1.2 -0.9 -1.0
Peak expiratory flow (PEF) 0.2 0.5 1.4 -0.8 -0.8 -0.5 -0.2 -1.0 -0.8 -0.4 -0.9 -0.9 -0.8 -1.2 -0.8 -0.4 -0.3 -0.5 0.3 -0.7 -0.5 -0.8 -0.7 -0.4 -0.7 -0.3 -0.6 -0.5 -0.7 -0.6 -0.9 -1.1 -0.4 -0.6 -1.2 -0.4 -0.6 -0.6 -0.3 -0.5 -0.6 -0.4 -0.1 -0.2 -0.9 -0.8 -0.7 -0.5 -0.9 -0.8 -0.7 -0.7 -0.9
Pulse wave reflection index 1.9 2.4 6.2 1.1 1.7 1.9 1.5 0.4 1.2 1.9 0.7 1.3 1.0 1.6 1.6 1.6 2.0 1.9 -2.0 0.1 1.9 1.4 1.9 1.4 1.7 1.6 1.9 1.9 1.1 1.8 -0.2 1.4 2.1 2.0 1.8 1.2 1.7 2.5 1.9 1.9 1.7 0.1 -2.3 -1.1 0.9 1.2 1.1 0.1 1.5 1.2 -0.1 1.3 1.2
Ever highly irritable/argumentative for 2 days 3.3 3.9 12.8 -0.6 -1.9 -2.8 0.4 0.6 -0.4 -0.7 -0.3 -1.7 -0.5 -0.0 -1.9 -2.4 -3.6 -2.8 3.5 1.9 -2.8 -1.1 -2.5 -1.1 -2.1 -2.4 -2.7 -2.7 -0.9 -2.3 2.3 -0.5 -2.8 -3.2 -1.6 -1.9 -2.5 -2.1 -2.4 -2.8 -2.6 2.0 2.0 2.7 -0.3 -0.7 -0.5 1.6 0.1 -1.0 1.8 -1.0 -0.9
Loud music exposure frequency 1.0 1.1 3.6 -0.9 -1.1 -1.3 -0.8 -0.5 -1.3 -1.0 -0.2 -0.5 -1.0 1.2 -1.0 -1.1 -1.0 -1.1 1.2 0.1 -1.3 -1.0 -1.0 -1.0 -1.2 -0.7 -1.2 -1.3 -0.9 -1.2 0.0 -0.8 -1.0 -1.2 -0.5 -0.0 -1.2 -1.4 -1.0 -1.3 -1.4 -0.0 1.8 1.1 -1.3 -0.8 -0.8 -0.6 -1.9 -1.3 -0.1 -1.0 -0.9
Qualifications: O levels/GCSEs or equivalent 0.1 0.1 1.4 0.2 -0.4 0.2 -0.4 -0.4 0.4 0.0 0.1 -1.2 0.3 -0.5 0.2 0.3 0.0 -0.0 -0.2 0.1 0.2 0.0 0.2 0.1 0.2 -0.4 0.1 0.2 0.3 0.2 -0.0 -0.4 0.2 -0.2 0.2 -0.1 0.2 -0.2 0.6 0.2 0.1 0.2 1.0 0.8 0.0 -0.2 0.3 -0.1 -0.7 0.2 0.2 0.1 0.3
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 3.7 -0.7 -1.2 -1.4 -0.0 -0.0 0.0 -1.1 -1.8 -1.4 -0.7 -1.0 -1.3 -1.4 -1.7 -1.6 1.6 0.1 -1.4 -0.5 -1.2 -0.8 -1.2 -1.6 -1.4 -1.3 -0.5 -1.3 -0.1 -0.6 -1.5 -1.8 -1.8 -0.4 -1.2 -1.9 -1.5 -1.4 -1.4 0.8 1.7 0.4 -0.7 -0.9 -0.6 -0.4 -0.7 -1.2 0.2 -0.9 -0.8
Blood clot in the leg (DVT) 0.2 0.3 0.7 0.6 0.6 0.6 0.5 -0.1 -0.2 0.5 0.5 0.7 0.6 0.3 0.7 0.8 0.6 0.7 -0.5 0.3 0.6 0.8 0.5 0.4 0.7 0.9 0.6 0.6 0.6 0.6 0.1 0.8 0.7 0.5 0.7 0.7 0.7 -0.4 0.6 0.6 0.2 0.5 -0.2 0.1 0.5 0.6 0.6 -0.2 -0.1 -0.0 0.4 0.6 0.4
Medication: Paracetamol 0.5 0.9 4.7 1.0 0.6 -0.0 1.0 1.4 0.4 0.6 1.7 1.1 1.4 0.6 0.6 0.5 -0.4 0.3 0.7 1.5 -0.0 1.3 -0.0 0.7 0.4 0.6 0.1 -0.0 1.1 0.4 2.2 1.2 -0.1 -0.1 0.5 -0.1 0.2 -0.7 -0.0 -0.0 0.0 2.1 1.1 1.2 1.2 1.1 1.1 1.3 0.8 1.0 1.7 1.1 0.9
Headache pain in last month 1.3 2.2 7.5 -0.1 -1.6 -1.9 -0.4 0.4 -0.3 -0.4 0.6 -2.2 -0.4 -1.0 -1.2 -1.4 -2.6 -1.7 2.7 1.6 -2.0 -0.7 -1.8 -0.5 -1.3 -2.0 -2.0 -1.9 -0.2 -1.7 1.5 0.0 -2.0 -2.5 -1.2 -1.7 -1.7 -1.9 -1.9 -1.9 -1.5 1.4 2.1 1.8 -0.5 -0.5 -0.0 0.6 -0.2 -0.7 1.7 -0.7 -0.4
Medication for cholesterol, blood pressure or diabetes 6.1 10.2 18.4 -4.0 -3.8 -2.6 -3.3 -4.3 -4.1 -3.7 -3.5 -3.8 -3.7 -1.7 -2.8 -2.4 -1.3 -2.5 1.1 -3.2 -2.5 -3.6 -2.3 -3.5 -3.2 -3.1 -2.7 -2.7 -3.8 -2.9 -3.3 -3.8 -2.7 -2.4 -3.5 -1.5 -2.8 -2.2 -2.3 -2.6 -2.9 -4.2 1.8 -2.3 -4.2 -4.0 -3.8 -3.3 -4.1 -3.5 -3.3 -3.7 -4.0
Glaucoma (self-reported) 0.4 0.5 1.0 -0.9 -0.7 -0.5 -0.2 -1.0 -0.1 -0.7 -0.2 -0.5 -0.8 -1.0 -0.5 -0.9 -0.3 -0.7 0.1 -1.0 -0.6 -0.8 -0.3 -0.9 -0.8 -0.4 -0.6 -0.5 -0.8 -0.7 -1.0 -0.8 -0.6 -0.6 -0.7 0.7 -0.6 -0.9 -0.7 -0.6 -0.8 -0.7 0.3 0.1 -0.6 -0.9 -0.8 -0.1 -1.0 -0.7 -0.8 -0.8 -0.7
Gout (self-reported) 0.0 0.1 0.5 0.2 0.2 -0.0 0.2 -0.3 -0.2 -0.1 0.3 0.4 -0.2 0.1 -0.1 -0.1 -0.1 0.0 0.0 0.3 -0.0 -0.2 0.0 -0.1 0.1 0.6 0.1 -0.0 -0.3 -0.1 -0.4 0.1 -0.1 0.1 -0.1 0.1 -0.1 0.1 0.1 -0.0 -0.3 0.3 -0.5 -0.0 -0.1 0.3 0.1 -0.7 -0.2 -0.4 0.3 -0.1 0.1
Hypothyroidism/myxoedema (self-reported) 0.1 0.3 1.4 0.5 -0.3 -0.2 0.1 0.7 -0.4 -0.0 0.6 0.0 0.2 0.7 -0.0 -0.5 -0.6 0.0 0.8 1.0 -0.2 0.4 -0.8 0.3 0.1 -0.3 -0.1 -0.2 0.0 -0.1 0.7 0.5 -0.2 -0.5 0.3 0.3 -0.1 -0.6 -0.1 -0.2 -0.6 0.9 -0.1 1.2 0.3 0.5 0.6 0.8 1.0 0.1 1.1 0.2 0.4
Medication: Amlodipine 6.6 9.2 16.2 3.6 3.5 2.8 2.7 3.4 3.5 3.6 3.0 3.8 3.6 3.0 3.1 2.3 1.3 2.5 -1.8 2.7 2.8 3.1 2.7 3.1 3.2 3.2 2.9 2.8 3.4 3.1 3.0 3.3 2.9 2.3 3.8 2.5 3.0 2.4 2.6 2.8 2.4 3.5 -1.5 2.2 4.0 3.7 3.5 3.0 3.1 3.4 2.6 3.7 3.7
Medication: Ventolin 100micrograms inhaler 0.1 0.2 1.0 -0.2 -0.1 -0.5 -0.7 0.2 0.1 0.3 -0.1 -0.5 -0.3 0.3 -0.1 -0.4 -0.6 -0.5 0.6 0.1 -0.5 -0.4 -0.1 -0.4 -0.5 -1.0 -0.5 -0.5 -0.2 -0.5 0.3 -0.5 -0.6 -0.5 -0.4 -0.6 -0.5 -1.0 -0.3 -0.5 -0.4 -0.0 -0.2 -0.5 -0.1 -0.3 -0.3 -0.1 0.2 -0.1 0.1 -0.4 -0.3
Birth weight 0.2 0.5 6.4 -0.6 -0.4 0.1 0.6 -0.9 -0.6 -0.3 -0.4 -0.6 -0.8 -1.2 -0.2 0.6 0.5 0.4 -0.5 -0.9 0.1 -0.7 0.1 -0.5 -0.2 0.5 0.1 0.1 -0.6 -0.1 -1.4 -0.7 0.1 0.5 -0.7 -1.4 0.0 0.1 0.4 0.1 0.6 -2.5 -0.1 -0.6 -0.7 -0.6 -0.6 -0.9 -0.3 -0.5 -1.1 -0.6 -0.5
Chronic bronchitis/emphysema (mother) 2.3 2.7 6.1 -2.0 -1.6 -1.2 -2.1 -1.9 -1.9 -1.9 -2.5 -1.1 -2.0 -1.0 -1.7 -1.2 -0.7 -1.5 0.3 -1.9 -1.2 -2.4 -1.0 -1.7 -1.6 -1.7 -1.2 -1.2 -2.2 -1.4 -1.8 -1.7 -1.2 -1.0 -1.8 0.2 -1.4 -0.9 -1.5 -1.2 -2.1 -1.5 0.1 -1.5 -1.9 -1.8 -2.0 -2.0 -1.7 -1.9 -1.8 -1.9 -2.1
High blood pressure (siblings) 1.5 2.1 9.9 1.6 1.1 0.1 0.8 2.5 1.9 1.7 2.4 1.1 1.9 1.8 1.0 0.1 -0.8 0.1 0.8 2.2 0.1 1.4 0.2 0.9 0.7 0.5 0.3 0.2 1.7 0.6 3.1 1.7 0.2 -0.5 1.9 1.1 0.5 -0.4 0.3 0.1 -0.1 2.6 2.1 2.2 1.9 1.7 1.6 1.5 1.3 2.1 2.3 1.4 1.6
Forced vital capacity (FVC), Best measure 0.8 2.8 8.3 -1.6 -2.2 -1.9 -0.8 -1.8 -1.5 -1.2 -1.4 -2.7 -1.7 -1.5 -1.9 -1.4 -1.8 -1.2 1.6 -0.6 -1.9 -2.1 -1.7 -1.5 -1.9 -1.7 -2.0 -1.9 -1.8 -1.9 -0.9 -1.7 -1.7 -1.9 -1.8 -2.9 -1.9 -1.2 -1.4 -1.9 -1.1 -1.3 1.2 0.3 -2.1 -1.9 -1.4 -1.1 -1.7 -2.0 -0.6 -1.8 -1.7
Body fat percentage 1.9 7.4 14.2 2.9 3.2 2.6 2.3 2.9 2.9 2.9 2.9 3.8 3.1 2.6 2.9 2.0 1.8 2.2 -1.7 1.8 2.6 3.3 2.4 3.1 2.9 3.0 2.8 2.6 3.1 2.8 2.2 2.9 2.6 2.4 3.0 3.3 2.7 2.0 2.4 2.6 1.8 3.5 -1.8 1.4 3.2 3.2 2.9 2.9 2.8 2.9 1.9 3.1 3.0
Leg fat percentage (right) 2.9 10.6 19.7 3.3 4.1 3.6 2.2 3.0 3.2 3.3 2.9 4.4 3.4 3.0 3.6 3.0 3.0 3.2 -2.9 1.4 3.6 3.7 3.5 3.4 3.7 4.0 3.8 3.6 3.4 3.7 1.7 3.2 3.5 3.6 3.5 3.6 3.7 2.8 3.2 3.6 2.9 2.6 -2.7 0.2 3.6 3.6 3.1 2.8 2.9 3.3 1.4 3.6 3.3
Arm fat-free mass (right) 0.2 0.8 6.0 -0.9 -0.7 -0.3 -0.8 -1.0 -0.1 -0.7 -0.3 -0.2 -1.0 -1.6 -1.1 -0.8 0.2 -0.8 -0.2 -1.6 -0.3 -0.8 -0.5 -0.9 -0.6 0.1 -0.3 -0.2 -0.8 -0.5 -2.1 -1.3 -0.2 -0.4 -0.9 2.4 -0.5 -0.1 -0.4 -0.3 -1.0 0.3 0.5 0.9 -0.9 -0.9 -0.9 -1.5 -1.6 -1.2 -1.3 -0.9 -0.7
Exposure to tobacco smoke outside home 0.6 0.8 3.7 -0.6 -1.2 -1.1 -1.5 0.2 -0.9 -1.0 0.2 -0.4 -0.7 -0.1 -0.5 -1.4 -1.2 -1.4 1.1 0.0 -1.0 -0.6 -1.1 -0.5 -0.9 -1.0 -1.0 -1.0 -0.5 -1.0 0.3 0.3 -1.1 -1.3 -0.6 0.6 -0.9 -0.6 -1.7 -1.1 -1.9 0.7 0.0 0.2 -0.5 -0.5 -0.6 0.4 0.1 -0.4 0.0 -0.8 -0.8
Comparative body size at age 10 0.3 0.7 3.1 -0.7 -0.5 -0.1 -1.1 -1.4 -0.4 -1.0 -1.5 -1.1 -1.0 -1.1 -0.7 -0.3 0.3 -0.3 -0.3 -1.2 -0.1 -0.9 -0.1 -0.7 -0.3 -0.8 -0.2 -0.1 -0.9 -0.3 -1.8 -0.8 -0.2 0.2 -0.6 0.4 -0.3 0.1 -0.5 -0.1 0.0 -1.7 0.6 -1.4 -1.4 -0.8 -0.7 -1.2 -1.3 -0.6 -1.0 -0.9 -0.7
Number of full brothers 0.4 0.5 1.7 0.1 0.1 -0.9 -0.1 1.2 -0.0 -0.2 0.6 0.8 0.3 0.8 -0.0 -0.8 -1.1 -0.7 1.3 1.1 -0.9 0.1 -1.0 -0.1 -0.6 -0.3 -0.7 -0.9 0.1 -0.7 1.3 0.4 -1.0 -0.7 -0.2 -1.0 -0.7 -0.4 -0.9 -0.9 -0.5 1.0 1.0 0.4 0.7 0.3 0.0 0.9 0.5 0.1 1.0 0.1 -0.0
Worry too long after embarrassment 1.2 2.0 19.2 -0.6 -1.2 -1.8 0.6 -0.1 -1.0 -1.3 -1.4 -2.1 -0.8 -1.1 -1.7 -1.2 -2.0 -1.1 2.1 0.8 -1.8 -1.1 -1.6 -0.8 -1.4 -1.7 -1.9 -1.8 -0.9 -1.6 0.7 -0.4 -1.9 -1.3 -1.5 -4.4 -1.7 -0.7 -1.9 -1.8 -0.3 -0.1 0.8 0.3 -1.0 -0.9 -0.7 -0.1 -0.4 -1.4 0.9 -1.0 -0.8
Seen a psychiatrist for nerves, anxiety, tension or depression 0.2 0.2 1.1 0.4 0.3 0.4 0.9 -0.0 1.0 0.3 0.1 0.7 0.2 1.1 -0.1 0.2 0.4 0.1 -0.2 0.3 0.3 0.4 0.5 0.1 0.3 0.4 0.3 0.4 0.0 0.3 -0.1 -0.0 0.2 0.2 0.8 0.8 0.2 0.4 0.7 0.3 0.1 0.4 -0.8 0.2 0.5 0.4 0.4 0.3 0.6 0.3 0.1 0.3 0.5
Wheeze or whistling in the chest in last year 1.3 2.3 4.6 1.3 2.0 1.7 1.2 1.8 2.1 1.7 1.2 2.1 1.6 0.4 1.8 1.5 1.6 1.3 -1.7 -0.0 1.6 1.9 1.9 1.4 1.5 1.8 1.7 1.7 1.8 1.7 0.6 1.1 1.7 1.7 1.4 1.9 1.8 1.8 1.5 1.7 1.5 1.4 -0.2 0.4 1.9 1.4 1.1 0.8 0.8 1.6 0.1 1.6 1.5
Number of children fathered 0.1 0.1 0.7 0.1 0.4 -0.3 -0.4 0.9 0.6 0.6 0.2 0.5 -0.0 0.6 -0.0 0.1 -0.3 0.2 0.5 0.2 -0.4 0.4 -0.0 -0.0 -0.3 0.3 -0.3 -0.3 0.4 -0.3 -0.2 0.2 -0.3 -0.1 -0.3 -0.6 -0.2 0.7 -0.4 -0.3 0.5 0.7 0.1 0.0 0.4 0.2 -0.1 -0.2 0.2 -0.4 0.3 -0.0 0.1
Reason for reducing amount of alcohol drunk: Health precaution 0.1 0.2 1.1 -0.1 0.5 0.0 0.5 0.2 0.7 -0.0 -0.8 0.6 -0.0 -0.9 -0.0 0.1 0.3 0.2 -0.2 -0.5 -0.0 0.4 0.4 0.1 -0.1 0.6 0.1 0.1 0.1 -0.0 0.0 -0.8 0.0 0.3 -0.2 0.1 0.1 1.0 0.2 0.0 0.5 0.2 -1.0 -0.2 0.5 -0.1 -0.3 -0.3 0.7 -0.3 -0.5 0.1 0.0
Age at first live birth 2.6 4.6 12.2 -2.6 -1.9 -1.4 -2.0 -3.3 -2.5 -2.3 -3.5 -2.2 -2.7 -2.3 -2.3 -1.6 -0.2 -1.5 0.4 -2.7 -1.3 -2.5 -1.8 -2.2 -1.9 -1.7 -1.4 -1.4 -2.6 -1.7 -3.1 -2.4 -1.4 -0.8 -2.6 -0.7 -1.7 -1.2 -1.6 -1.4 -1.5 -2.6 -0.3 -2.5 -3.0 -2.5 -2.5 -2.5 -2.4 -2.5 -2.5 -2.5 -2.6
Pulse wave peak to peak time 1.9 2.2 4.8 -1.4 -1.9 -1.6 -1.3 -1.3 -1.9 -2.2 -0.9 -1.2 -1.3 -0.4 -1.5 -1.6 -1.5 -1.8 1.5 -0.7 -1.6 -1.5 -1.9 -1.5 -1.6 -1.2 -1.6 -1.6 -1.6 -1.6 -0.6 -1.4 -1.6 -2.1 -1.8 0.2 -1.6 -2.2 -1.4 -1.6 -2.2 -0.6 1.4 0.1 -1.3 -1.4 -1.3 -0.7 -1.9 -1.6 -0.5 -1.4 -1.6
Health satisfaction 0.4 0.6 3.1 -0.6 -0.4 -1.0 -0.5 0.2 0.3 -0.8 -1.8 -0.3 -0.4 -0.2 -0.8 -1.2 -0.8 -1.2 1.0 -0.1 -1.0 -0.4 -0.8 -0.7 -0.9 -0.4 -0.9 -0.9 -0.5 -0.9 0.0 -0.4 -1.2 -0.8 -1.0 -0.1 -0.9 -0.2 -1.0 -1.0 -0.7 0.5 1.1 -0.1 -0.1 -0.6 -0.8 -0.5 -0.5 -0.6 -0.2 -0.6 -0.6
Shortness of breath walking on level ground 1.7 2.0 5.9 1.3 2.1 1.4 1.4 2.1 2.4 1.2 0.5 2.2 1.3 0.8 1.6 1.2 1.4 1.6 -1.2 0.2 1.4 2.1 1.8 1.4 1.3 1.9 1.5 1.5 1.6 1.4 0.3 1.3 1.2 1.7 1.0 1.0 1.6 1.3 0.8 1.4 1.9 1.2 -1.0 0.1 2.1 1.4 1.1 0.8 1.6 0.9 0.3 1.4 1.6
Qualifications: College or University degree 1.0 3.2 9.6 -2.2 -1.1 -0.7 -1.6 -3.1 -2.1 -1.8 -2.7 -1.4 -2.3 -1.4 -1.7 -0.6 0.4 -0.5 -0.4 -2.7 -0.6 -2.0 -1.0 -1.8 -1.3 -1.0 -0.8 -0.7 -2.2 -1.1 -3.1 -2.9 -0.6 0.0 -1.8 -1.4 -1.0 -0.8 -0.3 -0.7 -0.4 -3.0 -1.4 -2.9 -2.2 -2.2 -2.2 -2.2 -1.6 -2.1 -2.8 -2.0 -2.1
Eye problems/disorders: None of the above 0.5 0.5 1.5 -0.8 -0.7 -0.8 -0.7 -0.4 0.2 -0.7 -1.0 -0.6 -0.8 0.2 -1.1 -1.0 -0.6 -1.0 0.7 -0.4 -0.9 -0.6 -0.1 -1.0 -0.9 -1.0 -0.8 -0.8 -0.6 -0.9 -0.2 -1.0 -0.7 -0.9 -0.6 0.2 -0.9 -0.1 -0.6 -0.8 -0.9 -0.1 0.8 0.0 -0.4 -0.7 -0.8 -1.2 -0.1 -0.6 -0.5 -0.8 -0.7
Mouth/teeth dental problems: Loose teeth 0.3 0.3 2.4 -0.6 -0.2 -0.3 -0.5 -0.4 -0.3 -0.8 -1.5 -0.6 -0.4 -0.8 -0.5 -0.4 0.2 -0.0 0.1 -0.8 -0.3 -0.2 0.1 -0.6 -0.5 -0.3 -0.4 -0.3 -0.5 -0.4 -0.6 -0.6 -0.4 0.2 -0.9 -1.3 -0.4 -0.9 -0.8 -0.3 0.5 -0.6 -0.5 -1.0 -0.4 -0.8 -0.8 -0.4 -0.1 -0.6 -0.8 -0.4 -0.6
Emphysema/chronic bronchitis 0.1 0.1 1.0 -0.1 0.3 0.1 -0.3 0.4 -0.1 0.2 -1.0 -0.0 0.2 0.9 0.2 -0.0 0.3 0.0 -0.3 -0.1 0.1 0.1 0.3 -0.3 0.0 -0.1 0.2 0.1 -0.0 0.1 0.4 -0.2 0.2 0.5 -0.1 -0.7 0.1 0.6 0.1 0.1 0.2 -0.1 -0.4 -0.7 0.3 -0.0 -0.2 -0.5 0.2 0.0 -0.3 0.2 -0.1
Medication for pain relief, constipation, heartburn 6.2 10.5 18.5 -3.9 -3.6 -2.8 -3.6 -4.3 -3.5 -4.0 -3.9 -3.7 -4.1 -1.0 -3.3 -3.1 -1.5 -2.7 1.5 -3.0 -2.8 -3.9 -2.5 -3.4 -3.4 -3.3 -2.9 -2.8 -4.0 -3.2 -3.7 -3.9 -2.7 -2.4 -3.0 -1.4 -3.1 -2.1 -2.5 -2.8 -2.6 -3.8 0.1 -2.3 -4.1 -4.1 -3.8 -3.7 -3.4 -4.0 -3.2 -4.0 -3.9
Neck or shoulder pain in last month 4.2 5.9 10.4 3.0 2.3 2.2 2.8 2.6 2.6 3.1 2.6 1.6 3.2 1.9 2.9 2.2 1.0 2.3 -1.1 2.7 2.2 2.9 1.9 2.8 2.7 1.8 2.2 2.2 2.9 2.5 3.0 3.1 2.0 1.7 2.3 0.7 2.4 1.6 2.1 2.2 2.2 2.4 0.6 1.7 2.6 2.9 3.1 2.9 2.2 3.2 2.6 3.1 2.9
Medication: Blood pressure 4.2 7.5 13.5 3.1 3.5 2.7 2.3 3.3 3.7 3.4 2.6 3.3 2.9 1.2 2.7 2.4 1.9 2.4 -1.8 1.8 2.6 3.0 2.6 2.8 2.9 2.9 2.8 2.7 3.2 2.8 2.1 2.6 2.8 2.7 3.4 1.7 2.8 2.2 2.6 2.7 2.9 2.8 -2.0 1.4 3.5 3.1 2.9 2.0 3.2 2.8 1.9 3.1 3.3
Angina (self-reported) 3.2 4.3 10.4 2.3 2.1 1.4 2.9 2.9 1.3 2.2 2.1 2.7 2.6 1.1 2.3 1.5 0.8 1.7 -0.7 2.3 1.5 2.3 1.1 2.6 1.9 2.4 1.7 1.4 2.3 1.8 2.7 2.8 1.6 1.5 1.9 -0.1 1.7 0.9 1.4 1.4 1.6 2.3 -1.3 2.1 2.6 2.6 2.5 3.2 2.7 2.0 2.3 2.7 2.3
Migraine (self-reported) 1.6 1.9 7.5 -1.2 -1.9 -1.4 -1.3 -1.4 -0.7 -1.5 -1.3 -2.7 -1.3 -1.9 -1.4 -1.1 -1.2 -1.4 1.2 -0.8 -1.4 -1.3 -1.4 -1.3 -1.4 -1.9 -1.6 -1.4 -1.2 -1.4 -0.3 -1.2 -1.4 -1.7 -1.4 -1.1 -1.4 -1.6 -1.6 -1.4 -1.0 -1.0 1.3 -0.3 -1.5 -1.7 -1.3 -1.1 -1.8 -1.4 -0.6 -1.4 -1.3
Medication: Ibuprofen 4.8 5.8 9.7 2.7 3.1 2.4 2.9 3.0 2.5 3.1 1.8 2.5 2.9 -0.3 2.5 2.7 1.8 2.6 -1.8 1.7 2.4 2.5 2.4 2.6 2.7 2.4 2.6 2.4 2.8 2.6 1.9 2.6 2.5 2.5 2.1 0.7 2.6 1.4 2.4 2.4 2.7 1.8 -0.2 0.6 2.5 2.9 2.7 2.3 2.1 3.0 1.8 2.8 2.7
Medication: Allopurinol 0.2 0.2 1.7 -0.0 0.4 0.4 0.4 -0.6 -0.5 0.1 0.5 1.0 -0.2 0.1 0.1 0.4 0.5 0.4 -0.6 -0.2 0.4 -0.4 0.3 -0.1 0.3 0.9 0.4 0.3 -0.5 0.2 -0.9 -0.1 0.3 0.7 0.1 0.2 0.2 0.5 0.4 0.4 0.1 -0.5 -1.3 -1.0 -0.2 0.2 -0.0 -0.5 -0.3 -0.2 -0.3 -0.0 -0.0
Medication: Omeprazole 8.7 10.3 15.2 3.1 3.8 3.8 3.6 2.5 2.9 3.7 3.1 3.6 3.1 2.8 3.4 3.7 3.3 3.5 -3.4 1.3 3.8 3.2 3.7 3.2 3.7 3.9 3.8 3.8 3.2 3.7 1.1 2.9 3.8 3.8 3.7 2.1 3.7 2.7 3.8 3.8 3.4 1.2 -2.5 0.9 3.0 3.3 3.2 2.8 2.5 3.2 1.1 3.4 3.3
Medication: Seretide 50 evohaler 0.4 0.4 1.1 0.9 0.5 0.6 0.9 0.8 1.0 1.0 1.0 0.3 0.7 0.1 1.0 0.4 0.3 0.7 -0.3 0.7 0.6 0.9 0.6 0.7 0.7 0.5 0.5 0.6 0.8 0.6 0.7 0.7 0.6 0.1 0.4 -0.1 0.7 -0.2 0.7 0.6 0.6 0.7 0.1 0.9 0.9 0.7 0.9 0.3 0.5 0.4 0.7 0.7 0.9
Mean time to correctly identify matches 2.8 5.4 13.2 -2.4 -2.8 -2.6 -2.3 -1.9 -2.2 -2.3 -2.1 -3.3 -2.2 -1.9 -2.4 -2.6 -2.4 -2.6 2.2 -1.0 -2.6 -2.8 -2.7 -2.3 -2.6 -3.6 -2.7 -2.6 -2.2 -2.6 -0.9 -2.1 -2.6 -2.7 -2.5 -1.4 -2.6 -2.6 -2.3 -2.6 -2.5 -1.5 1.5 0.1 -2.4 -2.5 -2.4 -1.5 -1.7 -1.8 -1.0 -2.4 -2.4
Heart disease (mother) 0.1 0.1 2.6 -0.1 0.2 0.1 -0.2 0.1 -0.0 0.2 0.3 0.3 0.2 1.6 0.2 -0.0 0.0 0.1 -0.2 0.1 0.1 0.2 0.1 -0.0 0.1 0.0 0.2 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.7 -0.0 0.1 -0.3 0.0 0.1 -0.1 0.1 -0.5 0.2 0.3 -0.0 -0.0 0.2 0.6 0.4 -0.2 0.2 -0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.3 1.5 3.0 1.6 1.0 1.2 0.4 1.6 0.8 1.5 1.4 1.6 1.6 -0.2 1.6 1.1 0.7 1.0 -0.7 1.3 1.2 1.3 0.7 1.3 1.5 1.1 1.3 1.2 1.7 1.4 1.1 1.1 1.3 0.6 1.2 1.6 1.4 0.3 1.1 1.2 0.4 1.6 0.4 0.9 1.6 1.7 1.6 0.7 0.9 1.6 1.4 1.6 1.5
Whole body fat mass 0.8 3.5 9.1 2.0 2.1 1.7 1.5 2.0 2.2 1.9 2.1 2.7 2.1 1.3 1.8 1.2 1.1 1.3 -1.1 1.1 1.7 2.3 1.5 2.0 1.9 2.2 1.9 1.8 2.2 1.9 1.2 1.8 1.7 1.5 1.9 3.0 1.8 1.3 1.6 1.7 1.1 3.0 -1.2 1.6 2.2 2.2 2.0 1.9 1.7 1.8 1.3 2.1 2.0
Leg fat mass (right) 1.3 5.0 12.7 2.3 2.7 2.4 1.5 2.1 2.5 2.3 2.3 3.3 2.3 1.7 2.2 1.8 2.0 1.9 -1.9 0.8 2.4 2.5 2.2 2.2 2.5 2.8 2.5 2.4 2.4 2.5 0.9 2.0 2.4 2.3 2.3 3.6 2.4 1.9 2.1 2.4 1.6 2.5 -1.9 0.9 2.5 2.5 2.2 1.9 1.8 2.2 1.0 2.5 2.3
Arm predicted mass (right) 0.1 0.6 8.2 -0.5 -0.3 0.2 -0.5 -0.6 0.2 -0.4 0.0 0.3 -0.6 -1.1 -0.6 -0.5 0.5 -0.5 -0.5 -1.3 0.1 -0.4 -0.1 -0.5 -0.2 0.4 0.1 0.2 -0.4 -0.0 -1.9 -1.0 0.2 -0.0 -0.5 2.9 -0.0 0.2 0.0 0.2 -0.7 0.6 0.3 1.1 -0.6 -0.5 -0.5 -1.1 -1.3 -0.7 -1.1 -0.5 -0.3
Pulse rate, automated reading 0.3 1.0 6.0 0.2 -0.7 -1.1 -0.6 0.9 -0.2 -0.3 -0.3 -1.5 0.3 -0.5 -0.7 -0.7 -1.5 -1.0 1.7 1.4 -1.1 -0.4 -1.1 -0.2 -0.6 -1.6 -1.1 -1.1 0.2 -0.8 1.7 -0.1 -1.2 -1.2 -0.6 -1.4 -0.8 -1.8 -0.9 -1.1 -0.8 0.9 2.4 1.0 -0.2 -0.1 0.1 0.6 -0.4 0.3 1.4 -0.1 -0.1
Alcohol intake frequency. 0.8 2.0 5.2 1.8 1.2 1.1 1.8 2.1 1.5 1.2 1.0 0.6 1.9 0.0 1.6 1.0 0.2 1.2 -0.5 1.6 1.1 1.9 1.0 1.9 1.5 1.0 1.1 1.1 1.8 1.4 2.0 2.0 0.9 0.7 1.0 0.5 1.3 0.3 0.8 1.1 1.1 1.4 -0.0 1.3 1.4 1.6 1.9 2.3 1.8 1.8 1.7 1.8 1.7
Comparative height size at age 10 0.5 2.8 10.4 -1.4 -1.9 -1.5 -0.8 -1.5 -1.4 -1.6 -1.3 -2.7 -1.8 -3.2 -2.1 -1.3 -1.4 -1.5 1.2 -1.0 -1.5 -2.3 -1.1 -1.6 -1.5 -1.5 -1.6 -1.5 -1.5 -1.6 -2.4 -1.7 -1.4 -1.3 -2.0 -0.7 -1.6 -1.2 -1.6 -1.5 -1.1 -0.5 1.9 1.1 -2.3 -1.6 -1.3 -2.5 -2.4 -1.9 -0.6 -1.8 -1.4
Number of full sisters 3.7 4.6 8.5 2.1 2.9 2.2 2.2 2.3 2.0 2.2 1.7 2.8 2.2 2.7 2.5 2.0 1.9 2.6 -1.9 1.2 2.2 2.5 2.1 1.8 2.3 2.6 2.4 2.3 2.2 2.3 1.1 2.0 2.2 2.5 2.2 0.5 2.3 2.2 2.3 2.2 2.6 0.9 -1.6 -0.5 2.4 2.4 1.9 1.0 2.5 2.2 1.0 2.3 2.1
Suffer from ‘nerves’ 0.1 0.2 1.5 0.3 -0.4 -0.2 1.0 0.5 -0.0 -0.2 0.3 -0.3 0.3 0.4 -0.0 -0.3 -0.5 -0.1 0.5 0.8 -0.2 0.3 -0.5 0.3 0.0 -0.4 -0.2 -0.2 0.4 -0.1 0.3 0.7 -0.2 -0.5 -0.5 0.1 -0.1 -0.5 -0.4 -0.2 -0.5 1.2 1.1 1.2 -0.2 0.3 0.4 0.6 -0.5 0.1 0.7 0.2 0.2
Overall health rating 1.8 3.8 9.1 2.2 2.2 1.4 1.6 3.0 2.5 2.2 2.5 3.0 2.2 1.8 1.8 1.2 0.6 0.7 -0.5 2.0 1.4 2.4 1.3 1.8 1.7 1.9 1.6 1.4 2.3 1.6 2.4 2.6 1.3 1.1 2.1 2.8 1.6 0.9 1.1 1.4 0.7 2.8 0.5 1.9 2.6 2.5 2.1 2.0 2.0 2.5 1.8 2.2 2.2
Chest pain or discomfort 1.4 2.0 5.4 1.4 1.8 1.3 1.3 2.3 1.3 1.4 0.3 2.1 1.8 0.4 1.6 1.0 1.1 0.9 -1.0 1.0 1.3 1.9 1.1 1.4 1.4 1.5 1.5 1.3 1.9 1.5 1.3 1.4 1.4 1.5 1.4 1.4 1.5 1.0 1.3 1.3 1.1 1.5 -0.0 1.2 1.9 1.7 1.3 1.7 1.6 2.0 0.8 1.8 1.5
Had major operations 0.6 0.7 1.7 0.7 0.9 1.0 0.1 0.8 0.5 1.2 0.2 1.3 0.4 0.4 0.8 1.3 1.0 0.8 -1.0 0.1 1.0 0.8 1.1 0.9 0.9 0.6 1.1 1.0 0.7 0.9 -0.6 0.3 1.1 1.2 0.9 0.8 0.9 1.1 1.0 1.0 0.8 0.6 -1.2 -0.6 0.8 0.9 0.6 0.3 0.9 0.7 0.0 0.6 0.7
Age at last live birth 0.2 0.3 5.0 -0.4 -0.1 0.1 0.9 -1.0 -0.3 -0.8 -2.2 -0.5 -0.5 -0.6 -0.4 -0.0 0.4 0.0 -0.5 -0.8 0.1 -0.2 0.1 -0.1 -0.1 0.1 0.0 0.1 -0.3 -0.0 -1.3 -0.2 0.1 0.3 -0.5 -0.1 0.0 0.3 0.1 0.1 0.3 -0.2 -0.3 -1.0 -0.7 -0.5 -0.4 -0.6 -0.9 -0.4 -0.8 -0.3 -0.4
Family relationship satisfaction 2.0 2.5 5.4 -1.6 -1.4 -1.4 -1.6 -2.3 -1.4 -1.7 -1.9 -1.4 -1.8 -2.0 -1.9 -1.0 -0.6 -1.1 0.9 -1.4 -1.4 -1.8 -1.2 -1.8 -1.6 -0.9 -1.4 -1.4 -2.1 -1.6 -2.0 -1.8 -1.5 -0.9 -2.3 -1.2 -1.6 -0.4 -1.4 -1.4 -0.8 -1.8 0.6 -1.4 -1.6 -1.8 -1.8 -2.1 -1.9 -2.3 -1.3 -1.8 -1.6
Leg pain on walking 0.6 0.8 3.2 0.4 0.9 1.0 1.1 0.2 0.5 0.4 1.3 1.3 0.2 0.1 0.6 0.9 1.3 1.0 -1.2 -0.5 1.1 0.9 0.9 0.8 0.8 1.6 1.1 1.0 0.7 0.9 -1.0 0.2 1.0 1.3 0.7 1.0 0.9 0.9 1.0 1.0 0.8 0.1 -1.8 -0.0 0.3 0.5 0.5 0.6 0.5 0.1 -0.5 0.5 0.5
Qualifications: NVQ or HND or HNC or equivalent 0.2 0.3 1.7 -0.3 -0.6 -0.4 -1.3 0.3 0.1 -0.5 1.1 0.5 -0.5 -0.0 -0.3 -0.8 -0.3 -0.6 0.4 -0.4 -0.5 0.1 -0.4 -0.4 -0.5 -0.2 -0.4 -0.4 -0.0 -0.5 -0.3 -0.3 -0.5 -0.9 -0.3 0.8 -0.4 -0.4 -0.4 -0.4 -1.0 0.9 -0.3 0.5 0.3 -0.3 -0.4 -0.0 -0.2 -0.5 -0.3 -0.5 -0.3
Commuting to job workplace: Car/motor vehicle 0.9 1.0 2.7 1.2 1.1 0.6 1.1 1.2 0.8 1.2 1.4 1.0 1.3 1.6 1.1 0.9 0.1 0.8 -0.1 1.4 0.6 1.0 0.7 1.2 0.9 0.7 0.6 0.6 1.2 0.8 1.7 1.0 0.5 0.5 1.2 0.2 0.7 0.6 0.6 0.6 0.7 1.4 0.2 0.9 1.2 1.3 1.2 1.3 1.1 1.2 1.4 1.2 1.2
Illness, injury, bereavement, stress in last 2 years 2.6 3.2 6.8 -1.2 -2.0 -2.3 -1.7 -0.9 -2.1 -1.5 0.1 -2.1 -1.2 -1.4 -1.8 -1.7 -2.6 -1.7 2.6 0.4 -2.3 -2.1 -2.6 -1.6 -1.9 -2.4 -2.3 -2.3 -1.5 -2.1 0.4 -0.7 -2.4 -2.3 -2.0 -2.3 -2.2 -2.1 -2.3 -2.3 -1.9 -0.1 1.8 0.4 -1.4 -1.2 -1.1 -1.0 -1.2 -1.6 0.7 -1.5 -1.5
Medication: Aspirin 5.8 7.7 13.7 3.5 2.9 2.3 2.9 3.6 2.8 3.3 3.4 3.2 3.5 1.1 2.8 2.1 1.2 2.2 -1.1 3.2 2.3 2.8 2.0 2.8 3.0 2.8 2.5 2.3 3.2 2.7 3.2 3.5 2.4 1.8 2.9 1.5 2.6 2.0 2.3 2.3 1.9 3.0 -0.5 2.1 3.7 3.7 3.4 2.7 3.1 3.3 3.1 3.4 3.4
Supplements: Vitamin C 0.9 1.1 3.6 0.8 1.0 1.3 -0.1 0.3 1.3 1.4 1.9 0.9 0.7 -0.6 1.3 1.2 1.3 1.1 -1.4 -0.3 1.3 1.3 1.7 0.5 1.2 1.6 1.2 1.4 1.0 1.2 -0.3 0.2 1.1 0.9 0.8 1.4 1.3 0.3 1.4 1.3 1.1 0.1 -0.9 -0.5 0.9 0.6 0.7 -0.7 0.5 0.5 -0.2 0.8 1.0
Knee pain experienced in last month 6.6 10.3 18.8 3.4 3.5 3.3 2.7 3.3 2.8 3.4 4.0 4.3 3.5 2.9 3.7 2.9 2.4 2.6 -2.5 2.2 3.3 3.8 3.0 3.5 3.6 3.8 3.5 3.3 3.7 3.5 2.4 3.8 3.4 2.8 4.0 3.7 3.4 2.0 3.1 3.3 2.2 3.0 -0.3 2.2 3.3 3.8 3.6 3.2 2.2 3.6 2.1 3.6 3.5
Hypertension (Self-reported) 6.3 17.6 32.5 5.2 4.6 3.4 3.5 5.7 5.3 5.2 5.1 4.5 5.1 3.8 4.2 2.8 1.6 3.0 -1.7 4.4 3.3 4.9 3.5 4.3 4.2 3.6 3.6 3.5 5.2 3.9 5.1 5.2 3.6 2.7 5.1 3.1 3.8 2.1 3.4 3.4 3.3 4.9 -0.1 3.3 5.5 5.1 4.9 3.9 4.5 5.2 4.3 5.0 5.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.3 1.6 3.5 0.9 1.3 1.6 0.8 0.8 -0.1 0.8 1.2 1.5 1.4 0.5 1.8 1.2 1.6 1.0 -1.8 -0.0 1.7 1.0 1.4 1.4 1.5 1.4 1.7 1.5 1.3 1.7 0.2 0.9 1.6 1.6 1.2 1.6 1.6 1.1 1.6 1.6 0.7 0.9 -0.7 -0.3 1.0 1.2 1.0 0.5 1.1 1.9 0.0 1.5 0.9
Illnesses of father: Heart disease 0.2 0.3 1.4 0.2 -0.3 -0.7 -1.1 0.1 -0.0 -0.1 -0.3 -0.1 0.2 -0.3 -0.4 -1.0 -0.9 -0.6 1.2 0.8 -0.7 0.2 -0.7 -0.4 -0.3 -0.2 -0.6 -0.7 -0.0 -0.5 1.2 0.1 -0.6 -0.8 -0.3 -0.1 -0.6 -0.3 -0.7 -0.7 -0.5 0.8 0.9 0.3 0.5 0.2 0.2 -0.2 0.6 0.2 1.0 0.1 0.1
Illnesses of siblings: Diabetes 3.3 4.1 9.8 2.6 1.7 1.3 2.3 3.1 2.1 2.6 2.6 1.9 2.6 2.1 2.3 1.5 0.2 1.3 -0.3 2.7 1.3 2.3 1.4 2.3 1.9 1.4 1.4 1.3 2.6 1.7 2.5 2.8 1.2 0.7 1.8 0.6 1.6 1.1 1.4 1.3 1.1 2.8 0.4 1.8 2.5 2.7 2.6 2.2 2.3 2.4 2.7 2.4 2.4
Smoking status: Previous 0.3 0.4 3.4 0.5 0.4 0.1 0.3 0.7 -0.3 -0.2 0.4 1.9 0.4 -0.1 -0.0 -0.3 0.0 -0.0 0.1 0.5 0.1 0.9 0.1 0.4 0.2 1.3 0.2 0.1 0.4 0.2 0.6 0.7 0.2 -0.1 0.5 1.3 0.1 0.1 0.2 0.1 -0.3 1.5 -1.1 0.9 0.8 0.8 0.5 0.1 0.8 -0.2 0.6 0.5 0.5
Forced expiratory volume in 1-second (FEV1), predicted 1.7 3.6 7.0 -1.9 -2.4 -2.0 -1.2 -1.7 -1.1 -1.8 -0.7 -2.3 -2.2 -1.1 -2.2 -2.1 -1.8 -1.8 1.7 -1.2 -2.1 -2.2 -1.7 -1.8 -2.2 -1.9 -2.2 -2.0 -2.0 -2.2 -1.6 -2.3 -2.1 -2.2 -2.3 -0.6 -2.1 -1.3 -1.9 -2.0 -2.0 -0.6 1.6 1.1 -2.2 -2.1 -1.7 -1.4 -2.6 -2.5 -0.9 -2.4 -1.8
Whole body fat-free mass 0.4 2.2 6.6 -1.5 -1.8 -1.1 -1.4 -1.6 -0.6 -1.6 -0.7 -1.2 -1.7 -2.2 -1.9 -1.5 -0.6 -1.6 0.6 -1.8 -1.1 -1.6 -1.3 -1.7 -1.4 -0.9 -1.2 -1.1 -1.4 -1.3 -2.6 -2.1 -1.0 -1.4 -1.6 1.9 -1.3 -0.9 -1.1 -1.1 -1.7 0.2 1.2 1.4 -1.6 -1.6 -1.4 -1.9 -2.5 -2.0 -1.4 -1.7 -1.3
Leg fat-free mass (right) 0.4 1.9 3.8 -1.3 -1.7 -1.3 -1.1 -1.2 -0.3 -1.4 -0.3 -0.9 -1.5 -1.5 -1.8 -1.7 -1.0 -1.8 1.0 -1.1 -1.3 -1.3 -1.5 -1.4 -1.4 -0.9 -1.3 -1.2 -1.1 -1.4 -2.0 -1.7 -1.2 -1.6 -1.4 1.9 -1.4 -1.1 -1.3 -1.3 -1.9 0.8 1.1 1.8 -1.2 -1.3 -1.2 -1.4 -1.8 -1.9 -0.8 -1.5 -1.1
Arm fat percentage (left) 2.0 7.8 16.3 2.9 3.3 2.9 2.1 2.7 2.9 2.9 2.6 4.0 3.0 2.5 3.0 2.2 2.3 2.3 -2.3 1.3 2.9 3.4 2.6 3.0 3.0 3.3 3.1 2.9 3.1 3.0 1.6 2.5 2.9 2.7 3.1 3.9 3.0 2.1 2.7 2.9 2.0 3.1 -2.4 0.8 3.3 3.1 2.8 2.7 2.8 2.9 1.4 3.1 2.9
Average weekly red wine intake 0.2 0.2 1.2 0.1 0.5 0.5 -0.3 0.1 0.4 0.5 -0.7 0.1 0.1 -0.3 0.3 0.6 0.9 0.8 -0.6 -0.4 0.5 0.4 0.5 0.1 0.3 0.6 0.4 0.5 0.2 0.4 -0.4 -0.5 0.6 0.7 0.3 0.0 0.5 -0.2 0.8 0.5 1.0 -0.5 -0.0 -1.1 -0.1 -0.1 -0.2 -0.7 -0.9 -0.1 -0.5 0.2 0.2
Handedness (chirality/laterality): Left-handed 0.2 0.2 2.1 -0.3 0.1 0.0 0.2 -0.4 -0.3 -0.3 -0.5 -0.3 -0.5 -0.1 -0.1 0.4 0.5 0.7 -0.2 -0.5 0.1 -0.2 -0.2 0.0 -0.1 -0.1 0.0 0.0 -0.3 -0.1 -0.5 -0.6 -0.0 0.5 -0.5 -1.0 0.0 0.2 0.0 0.0 0.7 -1.0 -1.4 -0.7 -0.3 -0.4 -0.3 0.2 0.1 -0.5 -0.5 -0.3 -0.3
Mood swings 0.2 0.4 2.8 0.7 0.5 0.0 1.0 1.3 0.9 0.9 0.5 0.7 0.8 -1.3 0.3 0.1 -0.4 -0.1 0.3 0.8 0.0 0.7 0.2 0.6 0.3 0.3 0.1 0.1 0.7 0.2 0.8 0.9 -0.2 -0.1 -0.5 0.0 0.1 0.6 -0.2 0.0 0.0 1.7 0.4 0.8 0.8 0.7 0.7 0.5 0.5 0.3 1.0 0.7 0.6
Loneliness, isolation 0.3 0.4 2.1 0.5 -0.5 -0.5 0.6 0.6 -0.7 -0.3 -0.2 -0.3 0.4 -1.4 -0.3 -0.3 -0.9 -0.4 1.0 1.3 -0.4 -0.3 -1.0 0.2 -0.0 -0.2 -0.4 -0.5 0.0 -0.2 1.2 0.5 -0.7 -0.5 -0.7 -0.5 -0.4 0.2 -0.5 -0.5 -0.7 1.3 0.5 1.0 0.1 0.5 0.6 1.0 0.2 0.1 1.4 0.3 0.2
Long-standing illness, disability or infirmity 1.2 1.8 3.0 1.5 1.4 1.3 1.6 1.3 1.7 1.6 1.3 1.3 1.3 0.5 1.2 1.2 0.7 1.1 -0.9 0.9 1.3 1.4 1.1 1.4 1.5 1.3 1.4 1.4 1.5 1.4 0.8 1.6 1.4 1.1 1.5 1.7 1.3 0.8 1.3 1.3 1.1 1.1 -0.4 1.1 1.5 1.6 1.6 1.5 1.7 1.7 0.9 1.4 1.6
Ever had bowel cancer screening 0.1 0.1 0.8 -0.3 -0.5 -0.5 0.1 0.0 -0.2 0.3 -0.3 -0.3 -0.1 0.3 -0.3 -0.5 -0.3 -0.6 0.4 0.1 -0.5 -0.1 -0.4 -0.2 -0.4 -0.5 -0.5 -0.5 -0.3 -0.4 0.4 -0.5 -0.3 -0.6 -0.2 0.0 -0.4 -0.1 -0.1 -0.5 -0.3 -0.3 0.9 0.7 -0.3 -0.3 -0.2 -0.0 -0.2 0.1 0.0 -0.1 -0.2
Diabetes diagnosed by doctor 1.2 2.0 4.2 1.6 1.5 1.5 1.0 1.4 0.9 1.4 1.7 2.1 1.7 0.4 1.7 1.2 1.1 1.2 -0.9 0.9 1.5 1.6 0.8 1.5 1.7 2.0 1.6 1.5 1.6 1.6 1.2 1.4 1.5 1.3 1.4 1.7 1.6 0.7 1.3 1.5 0.8 1.8 -0.7 0.7 1.6 1.8 1.6 1.2 0.9 1.4 1.0 1.8 1.5
Ever had stillbirth, spontaneous miscarriage or termination 0.2 0.2 1.5 -0.3 -0.1 -0.4 -0.0 -0.2 0.7 0.3 -0.2 -0.4 -0.6 0.3 -0.6 -0.6 -0.1 -0.6 0.4 -0.2 -0.5 -0.2 -0.1 -0.6 -0.5 -0.5 -0.5 -0.3 -0.3 -0.5 -0.3 -0.4 -0.3 -0.5 0.0 0.2 -0.4 -0.1 -0.2 -0.4 -0.2 -0.5 1.2 -0.0 -0.4 -0.6 -0.5 -0.3 -0.8 -0.0 -0.4 -0.6 -0.2
Friendships satisfaction 0.8 0.9 3.0 -0.7 -0.9 -1.1 -0.8 -1.0 -0.8 -0.6 -1.7 -1.2 -1.0 -0.2 -1.2 -0.7 -0.8 -1.0 1.0 0.1 -1.1 -1.0 -0.9 -1.1 -1.0 -0.8 -1.1 -1.1 -1.1 -1.1 -0.8 -0.4 -1.0 -0.8 -1.1 -1.4 -1.1 -0.2 -1.1 -1.1 -0.5 -1.1 0.5 -1.1 -0.8 -0.9 -0.8 -1.7 -0.7 -1.4 -0.1 -1.0 -0.9
Qualifications: nursing, teaching 0.2 0.3 1.6 0.8 0.2 0.1 0.5 0.5 0.3 0.6 0.4 0.0 0.8 -0.7 0.3 0.6 -0.3 -0.1 0.4 1.1 0.1 0.3 -0.2 0.5 0.4 -0.2 0.1 0.1 0.5 0.3 1.2 0.6 0.1 0.1 0.5 -0.1 0.1 -0.5 0.2 0.1 0.1 0.9 1.1 1.0 0.2 0.8 0.8 0.9 0.0 0.8 1.2 0.5 0.7
Commuting to job workplace: Walk 0.3 0.3 2.2 -0.6 -0.8 -0.4 0.2 -0.3 -0.2 -0.2 -1.5 -1.0 -0.9 -0.7 -0.4 -0.5 -0.5 -0.5 0.2 -0.5 -0.5 -0.4 -0.5 -0.2 -0.6 -0.9 -0.5 -0.4 -0.3 -0.6 -0.9 -0.2 -0.4 -0.5 -1.0 -0.2 -0.4 -0.4 -0.5 -0.4 -0.5 -0.4 -0.0 -0.3 -0.8 -0.7 -0.5 0.2 -0.3 -0.5 -0.6 -0.9 -0.7
Eye problems/disorders: Cataract 1.0 1.1 2.2 1.2 1.2 1.1 0.8 1.1 0.3 0.7 1.4 1.5 1.3 1.1 1.5 1.3 0.5 1.1 -1.0 0.7 1.2 1.0 0.8 1.2 1.3 1.2 1.2 1.1 1.1 1.2 0.8 1.1 1.1 1.1 1.3 -0.1 1.2 0.5 1.1 1.1 1.0 0.9 -0.8 0.4 1.2 1.3 1.2 1.2 0.8 1.2 0.7 1.3 1.1
Mouth/teeth dental problems: Mouth ulcers 2.2 3.5 9.2 -1.8 -2.5 -2.0 -2.4 -2.0 -2.7 -2.2 0.2 -1.4 -1.9 0.9 -2.1 -2.2 -1.6 -2.2 1.9 -0.4 -1.9 -2.4 -2.9 -2.2 -1.9 -1.9 -1.9 -2.0 -2.1 -2.0 -0.5 -1.4 -1.7 -2.3 -0.5 0.1 -2.1 -2.3 -1.7 -2.0 -3.0 -0.8 1.1 1.5 -1.8 -1.7 -1.5 -1.0 -2.0 -1.8 -0.7 -2.0 -1.9
Medication for cholesterol 5.0 7.6 13.6 -3.5 -2.7 -2.1 -2.2 -3.7 -2.7 -3.1 -3.3 -3.3 -3.5 -1.5 -2.9 -1.9 -1.0 -2.1 0.7 -3.3 -2.1 -3.0 -2.1 -2.9 -2.8 -3.0 -2.3 -2.1 -3.2 -2.5 -3.4 -3.4 -2.2 -1.3 -3.2 -2.9 -2.4 -1.5 -2.3 -2.1 -1.5 -3.5 -0.4 -2.8 -3.6 -3.7 -3.5 -3.0 -2.4 -3.2 -3.3 -3.3 -3.4
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 4.1 0.1 -0.2 -0.9 -0.0 1.1 -0.1 0.0 0.9 0.2 0.5 0.8 0.0 -0.7 -1.6 -0.4 1.4 1.0 -0.9 0.2 -1.3 -0.3 -0.6 -0.2 -0.8 -0.9 0.1 -0.6 2.0 0.1 -0.9 -1.2 0.4 -1.4 -0.7 -0.2 -0.5 -0.9 -0.5 1.4 1.3 1.5 0.5 0.3 0.1 1.0 0.4 0.3 1.1 0.3 0.1
Back pain experienced in last month 0.4 0.6 2.7 0.8 0.7 0.1 1.2 1.2 1.2 0.8 1.2 1.0 0.7 0.3 0.5 0.2 -0.2 0.1 0.2 0.9 0.1 1.1 0.4 0.7 0.3 0.5 0.2 0.2 1.1 0.2 1.2 0.9 0.2 -0.0 1.0 0.5 0.3 -0.0 -0.1 0.1 0.2 1.4 1.1 1.6 0.8 0.9 0.8 1.5 0.6 0.9 0.9 0.6 0.9
Mineral and other dietary supplements 0.3 0.4 1.5 0.0 -0.3 -0.7 0.2 1.0 0.2 -0.0 0.4 -0.4 -0.0 0.8 -0.0 -0.3 -1.1 -0.6 1.1 0.9 -0.7 -0.2 -1.0 0.1 -0.5 -0.7 -0.7 -0.7 0.0 -0.6 1.1 0.2 -0.5 -0.9 0.1 -1.0 -0.5 -0.4 -0.5 -0.7 -0.5 0.4 0.5 1.2 0.3 0.0 0.1 1.2 0.6 0.0 0.7 -0.1 -0.1
Breast cancer (self-reported) 2.2 2.6 4.8 -1.7 -1.7 -1.8 -1.8 -1.4 -2.2 -1.9 -0.8 -1.5 -1.8 -0.8 -1.7 -2.0 -1.4 -1.7 1.4 -0.8 -1.7 -2.1 -1.6 -1.8 -1.8 -1.7 -1.7 -1.8 -1.8 -1.8 -1.1 -1.7 -1.8 -1.4 -1.8 -0.5 -1.8 -1.9 -1.8 -1.8 -2.0 -1.1 0.8 -0.4 -1.8 -1.5 -1.5 -1.4 -1.2 -1.6 -0.7 -1.9 -1.8
Asthma (self-reported) 0.2 0.4 2.2 -0.5 -0.8 -0.6 -0.5 -0.3 -1.0 -0.1 -1.4 -1.0 -0.6 -0.2 -0.3 -0.3 -0.4 -0.3 0.5 -0.0 -0.5 -0.7 -0.4 -0.5 -0.5 -1.1 -0.6 -0.6 -0.4 -0.6 -0.2 -0.2 -0.5 -0.5 -0.9 -0.9 -0.5 -1.5 -0.6 -0.6 -0.7 -0.6 0.8 -1.1 -0.6 -0.6 -0.5 -0.6 -0.8 -0.2 -0.1 -0.6 -0.7
Osteoporosis (self-reported) 0.1 0.2 1.3 -0.3 -0.1 0.0 0.0 -0.6 -0.8 -0.3 -1.1 -0.3 -0.2 -0.6 -0.4 0.3 0.3 -0.0 -0.2 -0.3 0.0 -0.3 -0.1 0.0 -0.1 -0.0 0.0 -0.0 -0.4 -0.0 -0.3 -0.4 0.1 0.3 -0.3 -0.6 -0.0 0.5 0.3 0.0 0.2 -1.1 -0.4 -0.7 -0.5 -0.2 -0.2 -0.7 0.4 0.0 -0.3 -0.1 -0.3
Osteoarthritis (self-reported) 2.6 3.3 11.5 1.5 2.4 2.0 0.9 1.8 1.5 1.4 2.8 3.4 1.8 1.5 1.8 1.6 1.6 1.5 -2.0 0.3 2.0 1.8 2.0 1.5 1.9 2.8 2.2 2.0 1.7 2.0 0.7 1.4 2.1 1.9 2.5 2.5 2.0 1.2 1.8 2.0 1.2 1.4 -1.2 1.1 2.1 2.0 1.5 0.9 1.8 1.8 0.3 1.9 1.7
Medication: Aspirin 5.3 6.8 12.4 3.4 2.8 2.1 2.6 3.5 2.8 3.3 3.1 3.1 3.2 0.8 2.5 1.9 1.1 1.9 -0.9 3.1 2.1 2.7 1.9 2.6 2.7 2.7 2.3 2.2 3.0 2.5 3.1 3.3 2.2 1.5 2.8 1.8 2.4 1.9 2.2 2.1 1.7 2.9 -0.0 2.2 3.5 3.5 3.3 2.6 2.7 3.2 3.1 3.2 3.3
Medication: Gliclazide 0.1 0.1 0.6 -0.4 -0.4 0.1 -0.4 -0.8 -0.6 -0.3 0.2 -0.4 0.0 0.1 0.1 0.1 0.6 0.1 -0.3 -0.5 0.1 -0.3 -0.3 -0.2 -0.1 -0.1 0.0 0.0 -0.2 0.1 0.2 -0.7 0.2 0.1 0.4 0.3 0.0 0.0 0.4 0.1 0.1 -0.3 -0.5 0.1 -0.1 -0.5 -0.4 -0.0 -0.3 -0.0 -0.7 0.1 -0.4
Illnesses of father: None of the above (group 1) 0.1 0.2 2.5 -0.1 0.1 0.1 1.4 0.4 -0.3 -0.5 -0.3 -0.5 -0.1 -0.6 0.3 0.6 0.1 0.4 -0.2 -0.3 0.1 -0.1 -0.1 0.7 0.0 -0.3 0.0 0.1 0.3 0.1 -0.7 0.2 -0.1 0.3 -0.6 -1.6 0.2 -0.3 -0.0 0.1 0.4 0.1 -0.4 -0.1 -0.4 -0.2 -0.1 0.2 -0.3 -0.4 -0.2 -0.1 -0.2
Smoking status: Current 0.3 0.4 2.6 0.5 0.2 -0.4 0.4 1.1 0.6 0.3 -0.3 0.8 0.5 1.6 0.3 -0.6 -0.6 -0.5 0.7 1.2 -0.4 0.8 -0.3 0.2 -0.1 0.6 -0.3 -0.4 0.3 -0.2 1.5 0.8 -0.3 -0.4 0.5 0.4 -0.2 0.3 -0.7 -0.4 -0.4 1.2 0.6 0.9 0.7 0.5 0.5 0.8 0.7 0.3 1.1 0.4 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.1 1.5 -0.2 -0.4 -0.4 -0.1 -0.2 0.3 0.0 -0.4 -0.9 -0.1 0.5 -0.3 -0.3 -0.4 0.1 0.4 0.2 -0.4 -0.2 -0.0 0.0 -0.4 -0.4 -0.5 -0.3 -0.3 -0.3 0.3 -0.1 -0.3 -0.5 -0.2 -1.2 -0.3 0.0 -0.0 -0.4 0.3 -0.7 -0.3 -0.5 -0.0 -0.4 -0.1 0.5 0.3 0.0 -0.0 -0.1 -0.2
Whole body water mass 0.3 2.0 6.6 -1.4 -1.7 -0.9 -1.3 -1.6 -0.5 -1.4 -0.8 -1.1 -1.6 -2.1 -1.8 -1.4 -0.4 -1.5 0.5 -1.8 -1.0 -1.5 -1.2 -1.5 -1.3 -0.7 -1.1 -0.9 -1.3 -1.2 -2.6 -2.0 -0.9 -1.2 -1.5 2.0 -1.1 -0.7 -1.0 -1.0 -1.6 0.2 1.0 1.3 -1.5 -1.6 -1.4 -1.9 -2.3 -1.9 -1.4 -1.6 -1.3
Leg predicted mass (right) 0.4 1.9 4.0 -1.3 -1.7 -1.3 -1.2 -1.1 -0.4 -1.4 -0.3 -0.8 -1.5 -1.4 -1.7 -1.8 -1.1 -1.8 1.1 -1.1 -1.3 -1.3 -1.6 -1.4 -1.4 -1.0 -1.4 -1.3 -1.1 -1.4 -1.9 -1.7 -1.2 -1.7 -1.4 1.9 -1.4 -1.1 -1.3 -1.3 -2.0 0.9 1.1 1.8 -1.2 -1.3 -1.2 -1.3 -1.8 -1.8 -0.8 -1.5 -1.1
Arm fat mass (left) 1.3 5.3 15.4 2.3 2.6 2.5 1.6 2.0 2.5 2.3 2.3 3.4 2.4 1.7 2.4 1.9 2.1 2.0 -2.1 0.7 2.5 2.8 2.1 2.4 2.6 2.9 2.6 2.5 2.5 2.6 0.8 1.9 2.5 2.3 2.4 3.9 2.5 1.8 2.3 2.5 1.5 2.9 -2.0 1.0 2.6 2.5 2.3 2.0 1.8 2.1 0.9 2.5 2.4
Number of self-reported non-cancer illnesses 3.4 5.9 11.4 2.6 2.6 2.2 2.0 3.1 1.8 2.8 3.4 3.1 2.9 2.6 2.7 2.0 1.4 2.1 -1.5 2.0 2.2 2.8 1.5 2.6 2.6 2.4 2.4 2.2 2.8 2.5 2.6 2.6 2.4 2.0 3.1 2.1 2.4 0.9 2.4 2.2 1.7 2.6 -0.7 1.8 2.9 2.9 2.6 2.3 2.7 3.2 1.9 2.9 2.7
Average weekly champagne plus white wine intake 0.1 0.1 0.6 0.1 -0.3 0.2 -0.3 -0.7 0.1 0.1 0.1 -0.5 -0.1 -0.3 -0.1 -0.1 0.0 -0.2 -0.2 -0.2 0.2 -0.4 -0.0 -0.4 0.2 -0.2 0.1 0.2 -0.2 0.1 -0.7 0.3 0.1 -0.1 -0.2 0.6 0.1 0.4 -0.1 0.2 -0.3 -0.1 0.1 0.1 -0.2 -0.1 0.1 -0.8 -0.2 0.1 0.0 -0.1 0.0
Miserableness 0.3 0.6 1.3 -0.8 -0.8 -1.0 -0.6 -0.2 -1.0 -0.5 -0.2 -0.3 -0.8 -0.3 -0.8 -0.7 -0.9 -1.1 0.8 -0.4 -0.9 -0.8 -1.1 -0.6 -0.9 -0.7 -0.9 -1.0 -0.9 -0.9 -0.2 -1.0 -1.0 -0.9 -1.0 -1.0 -1.0 -0.5 -0.7 -0.9 -1.1 -0.4 0.1 0.1 -0.8 -0.6 -0.7 -0.4 -0.4 -1.1 -0.3 -0.8 -0.9
Guilty feelings 0.3 0.5 1.5 -0.6 -0.4 -0.9 -0.5 -0.1 -0.1 -0.7 -1.2 -0.6 -0.6 -0.5 -1.0 -0.8 -0.7 -1.0 0.8 -0.1 -0.9 -0.5 -0.8 -0.5 -0.9 -0.6 -0.9 -0.8 -0.5 -0.9 -0.1 -0.2 -0.9 -0.7 -0.6 -0.4 -0.9 -0.6 -1.2 -0.9 -0.7 -0.0 0.7 -0.4 -0.8 -0.6 -0.6 -0.1 -0.5 -0.4 -0.1 -0.7 -0.5
Wears glasses or contact lenses 0.6 0.6 3.9 -0.9 -0.7 -0.3 -1.3 -1.4 -1.3 -1.0 -1.1 0.0 -0.6 -0.7 -0.6 -0.5 0.0 -0.8 -0.1 -1.1 -0.3 -0.9 -0.6 -0.7 -0.5 -0.3 -0.3 -0.4 -0.9 -0.4 -1.0 -0.5 -0.3 -0.4 -0.9 2.0 -0.5 -0.5 -0.8 -0.3 -1.2 -0.4 -0.1 -0.5 -1.0 -0.7 -0.8 -1.6 -0.5 -0.5 -1.0 -0.5 -1.0
Ever taken oral contraceptive pill 0.3 0.3 2.4 -0.3 -0.9 -0.2 -1.3 -0.8 -1.2 -0.2 0.5 -0.7 -0.2 -1.6 -0.1 -0.5 -0.2 -0.4 0.2 -0.3 -0.2 -0.6 -1.3 -0.2 -0.2 -0.6 -0.2 -0.3 -0.2 -0.2 -0.2 -0.3 -0.1 -0.6 -0.5 0.2 -0.2 -0.9 -0.3 -0.2 -1.2 0.1 0.6 0.3 -0.6 -0.3 -0.2 -0.4 -0.7 -0.1 -0.0 -0.4 -0.4
Hearing aid user 0.2 0.2 2.9 -0.1 0.0 -0.2 -0.8 0.4 -0.6 -0.5 -0.6 0.3 0.1 -1.7 -0.0 -0.1 -0.1 -0.3 0.2 -0.1 -0.2 -0.3 0.0 -0.1 -0.1 0.1 -0.1 -0.2 0.1 -0.1 0.2 -0.2 -0.3 0.1 -0.8 -0.1 -0.1 -0.5 -0.4 -0.2 -0.3 -0.1 0.4 -0.9 0.0 0.1 -0.2 -0.8 0.3 0.2 0.2 0.0 -0.3
Mother’s age at death 0.6 0.8 2.3 1.1 0.7 0.7 1.3 0.9 0.9 0.7 0.1 0.0 1.1 0.4 1.2 0.8 0.3 0.9 -0.3 0.9 0.7 1.4 0.8 1.4 0.9 0.3 0.6 0.7 1.1 0.8 0.9 0.7 0.7 0.5 0.3 -0.1 0.9 0.7 1.0 0.7 1.2 0.9 -0.1 1.0 0.9 0.8 1.1 1.5 1.0 1.1 1.0 1.2 1.1
Financial situation satisfaction 0.3 0.4 2.3 0.6 0.2 -0.2 0.8 0.8 0.5 -0.1 -0.0 0.5 0.6 0.8 -0.2 -0.2 -0.7 -0.4 0.7 1.2 -0.2 0.1 -0.6 0.1 0.1 0.2 -0.1 -0.2 0.3 -0.0 1.0 0.9 -0.2 -0.5 0.4 0.7 -0.1 -0.6 -0.3 -0.2 -0.6 1.4 1.5 1.3 0.5 0.6 0.6 0.7 -0.5 0.2 1.0 0.4 0.4
Tinnitus: Yes, now most or all of the time 2.6 3.0 6.0 -1.5 -2.2 -2.1 -2.5 -1.5 -2.4 -1.5 -1.4 -1.6 -1.9 -1.1 -2.0 -1.8 -1.7 -1.5 1.9 -0.2 -2.1 -1.8 -2.1 -1.8 -1.9 -1.6 -2.1 -2.1 -1.8 -2.1 -1.1 -1.5 -2.1 -1.9 -1.9 -2.1 -2.1 -2.0 -2.1 -2.1 -1.6 -1.2 0.5 -0.3 -1.4 -1.5 -1.5 -1.5 -0.8 -2.0 -0.1 -1.9 -1.6
Commuting to job workplace: Public transport 1.6 1.9 3.5 -1.7 -1.9 -1.3 -0.9 -1.4 -1.3 -1.8 -1.8 -1.4 -1.8 -1.0 -1.7 -1.5 -0.7 -1.5 0.7 -1.3 -1.3 -1.2 -1.4 -1.5 -1.6 -1.1 -1.4 -1.3 -1.5 -1.5 -1.7 -1.4 -1.3 -1.3 -1.2 -0.4 -1.4 -1.3 -1.4 -1.3 -1.5 -1.1 -0.5 -0.2 -1.3 -1.9 -1.7 -1.1 -0.7 -1.7 -1.5 -1.6 -1.6
Eye problems/disorders: Glaucoma 0.4 0.4 2.4 -0.9 -0.1 0.2 -0.1 -1.2 -0.6 -0.5 0.0 0.1 -0.7 -0.0 -0.0 0.1 0.8 0.3 -0.8 -1.6 0.2 -0.6 -0.0 -0.4 -0.2 0.3 0.2 0.2 -0.7 0.0 -1.5 -0.7 0.2 0.5 -0.3 0.8 0.1 -0.2 0.2 0.2 -0.1 -1.3 -1.1 -1.1 -0.7 -0.8 -0.8 -0.0 -0.7 -0.5 -1.5 -0.5 -0.7
Medication: Blood pressure 2.8 5.4 12.2 2.7 2.4 2.0 1.2 2.9 2.5 2.3 2.9 3.1 2.9 1.8 2.6 1.3 1.3 1.6 -1.2 2.2 2.0 2.6 2.3 2.0 2.4 2.4 2.1 2.0 2.7 2.3 2.9 2.8 2.1 1.2 2.9 3.5 2.2 1.1 2.0 2.0 1.0 2.7 0.8 2.3 3.1 2.8 2.7 1.8 1.5 2.8 2.1 2.8 2.8
Pain type(s) experienced in last month: Hip pain 4.8 6.0 14.0 2.7 2.7 2.3 1.7 2.5 2.4 3.4 3.7 3.5 2.4 2.2 2.5 2.2 1.7 2.2 -1.5 2.0 2.3 3.0 2.1 2.4 2.6 3.1 2.4 2.3 2.5 2.4 1.7 2.7 2.5 1.8 3.2 2.4 2.4 1.9 2.5 2.3 1.9 2.1 -1.2 1.7 3.0 2.9 2.7 2.1 2.6 2.4 1.8 2.6 2.9
Supplements: Fish oil (including cod liver oil) 0.4 0.5 1.5 0.9 0.9 0.8 0.7 0.4 0.8 1.0 0.2 0.8 0.9 0.2 0.8 0.5 0.5 1.0 -0.5 0.4 0.8 1.2 1.1 0.8 0.8 0.8 0.7 0.8 0.9 0.8 0.1 0.9 0.6 0.8 0.5 0.2 0.8 0.7 0.5 0.8 0.9 1.0 -0.5 -0.1 0.7 0.8 0.8 0.2 0.7 0.5 0.5 0.9 0.9
High cholesterol (Self-reported) 4.9 8.6 16.3 3.6 3.3 2.4 3.8 3.7 2.9 3.2 2.2 3.4 3.6 1.7 2.6 2.4 1.3 2.4 -1.1 3.4 2.4 3.0 2.3 3.3 3.0 2.8 2.6 2.4 3.2 2.8 3.2 4.0 2.5 2.3 3.0 1.2 2.6 2.6 2.4 2.4 2.3 3.2 -1.1 1.6 3.6 3.9 3.6 3.4 4.0 3.8 3.2 3.6 3.5
Medication: Bendroflumethiazide 6.4 9.7 19.6 2.8 4.0 3.9 1.5 2.5 3.1 3.4 2.1 4.0 2.9 1.3 3.4 3.0 3.7 3.5 -3.7 0.4 3.9 3.2 3.9 2.8 3.6 3.9 4.0 3.9 3.2 3.8 0.9 2.8 3.9 4.0 3.4 4.4 3.9 2.5 3.5 3.9 3.1 1.6 -1.9 -0.6 2.9 3.1 2.6 0.8 1.6 3.1 0.4 3.2 3.1
Medication: Paracetamol 1.9 2.9 8.5 2.1 1.8 1.0 1.8 2.3 1.4 1.7 2.6 2.2 2.5 1.1 1.5 1.4 0.5 1.4 0.0 2.1 1.0 2.2 0.8 1.6 1.5 1.7 1.2 1.0 2.1 1.4 2.8 2.1 1.0 0.9 1.5 0.6 1.2 0.0 1.1 1.0 1.1 2.9 0.4 1.7 2.4 2.2 2.1 2.0 1.7 1.9 2.2 2.2 2.1
Medication: Lisinopril 1.8 2.3 5.5 1.8 1.5 1.3 1.2 1.6 1.5 1.6 1.3 1.9 1.7 0.8 1.6 1.3 0.9 1.0 -0.7 1.6 1.3 1.7 1.1 1.9 1.6 1.3 1.4 1.3 1.6 1.5 1.9 1.8 1.4 1.0 2.3 1.7 1.4 1.0 1.4 1.3 0.9 1.5 -0.4 1.0 1.7 1.9 1.8 1.7 1.5 1.9 1.6 1.7 1.8
Medication: Atorvastatin 1.1 1.4 3.0 1.5 1.1 0.9 1.3 1.0 0.3 0.8 1.7 1.4 1.7 0.8 1.1 0.9 0.5 1.1 -0.5 1.6 1.0 1.0 0.4 1.1 1.3 1.6 1.1 0.9 1.1 1.2 1.6 1.5 1.1 0.7 1.7 0.6 1.0 -0.0 1.0 0.9 0.6 1.5 -0.5 1.4 1.4 1.7 1.6 1.2 1.0 1.2 1.6 1.7 1.4
Illnesses of father: High blood pressure 0.3 0.4 3.9 0.6 0.0 -0.4 -0.2 0.4 -0.1 0.7 0.4 0.4 0.2 0.3 -0.0 -0.6 -0.9 -0.4 1.0 1.4 -0.4 -0.1 -0.2 -0.3 -0.0 -0.2 -0.3 -0.4 0.2 -0.3 0.9 0.6 -0.3 -0.6 0.2 0.5 -0.4 -0.8 -0.2 -0.4 -0.7 0.4 2.0 0.7 0.2 0.9 0.7 0.1 0.0 0.3 1.5 0.1 0.4
Alcohol drinker status: Never 0.2 0.3 2.5 0.4 0.5 0.4 0.4 0.4 0.3 0.8 -1.6 -0.0 0.3 0.3 0.4 0.5 0.5 0.6 -0.4 0.5 0.4 0.2 0.4 0.1 0.5 0.1 0.4 0.4 0.3 0.4 0.3 0.3 0.3 0.6 -0.1 -0.3 0.4 0.1 0.4 0.4 0.7 -0.9 -0.2 -1.6 0.0 0.3 0.3 0.1 0.3 0.6 0.2 0.3 0.3
Ever smoked 0.5 0.8 5.6 1.0 0.9 0.3 0.8 0.9 0.7 0.7 0.5 2.4 0.7 0.9 0.4 0.2 0.1 0.2 0.0 1.1 0.3 1.2 0.5 0.5 0.6 1.8 0.5 0.4 0.4 0.4 1.0 1.3 0.5 0.2 1.1 1.2 0.3 0.9 0.1 0.3 0.1 1.9 -1.2 1.2 1.5 1.1 0.9 0.9 1.0 0.2 1.0 0.9 1.1
Basal metabolic rate 0.2 1.0 5.4 -0.9 -1.1 -0.5 -0.9 -1.1 0.0 -0.9 -0.2 -0.5 -1.1 -1.6 -1.2 -1.0 -0.2 -1.1 0.3 -1.3 -0.6 -0.9 -0.8 -1.0 -0.8 -0.3 -0.6 -0.5 -0.8 -0.7 -2.0 -1.4 -0.5 -0.9 -1.0 2.3 -0.7 -0.5 -0.6 -0.5 -1.3 0.7 0.8 1.6 -0.9 -1.0 -0.8 -1.3 -1.8 -1.4 -1.0 -1.0 -0.7
Leg fat percentage (left) 3.5 12.5 24.4 3.6 4.4 3.8 2.5 3.4 3.4 3.6 3.3 4.9 3.8 3.5 3.9 3.1 3.0 3.4 -3.1 1.7 3.8 4.0 3.7 3.7 4.0 4.3 4.0 3.8 3.8 4.0 2.1 3.5 3.8 3.8 3.9 4.0 3.9 2.8 3.5 3.8 3.0 3.0 -2.7 0.4 4.0 4.0 3.5 3.1 3.3 3.7 1.7 4.0 3.7
Arm fat-free mass (left) 0.1 0.5 6.5 -0.5 -0.4 0.1 -0.5 -0.6 0.2 -0.5 0.1 0.1 -0.5 -1.0 -0.6 -0.4 0.3 -0.4 -0.3 -1.2 0.0 -0.4 -0.2 -0.5 -0.2 0.3 0.0 0.1 -0.4 -0.1 -1.7 -0.8 0.1 -0.1 -0.5 2.5 -0.1 0.1 -0.1 0.1 -0.7 0.8 0.0 1.1 -0.5 -0.5 -0.4 -0.9 -1.3 -0.9 -0.9 -0.4 -0.3
Number of operations (self-reported) 1.0 1.5 3.9 0.8 1.6 1.4 0.8 1.1 1.2 2.0 1.6 1.9 0.6 0.6 1.4 1.6 1.5 1.3 -1.7 -0.4 1.4 1.2 1.3 0.8 1.2 1.5 1.5 1.5 1.1 1.3 -0.7 0.3 1.6 1.6 1.2 1.2 1.4 1.1 1.5 1.4 1.4 0.0 -1.5 -0.3 1.3 0.9 0.6 0.1 0.9 1.0 -0.4 0.9 1.0
Average weekly beer plus cider intake 3.8 5.6 9.9 -2.4 -2.6 -2.7 -2.5 -2.1 -1.7 -2.1 -1.9 -1.8 -2.7 -1.9 -2.6 -2.7 -2.4 -3.1 2.2 -1.4 -2.7 -2.6 -2.0 -2.8 -2.8 -2.6 -2.7 -2.6 -2.6 -2.8 -1.5 -2.6 -2.7 -2.8 -2.5 -0.3 -2.8 -1.7 -2.5 -2.7 -3.1 -0.9 1.8 -0.2 -2.2 -2.4 -2.5 -1.8 -2.4 -2.6 -1.2 -2.9 -2.5
Irritability 0.2 0.4 3.2 0.7 0.3 0.2 1.0 1.1 0.7 0.8 0.6 0.4 1.0 -0.6 0.4 0.3 -0.2 -0.1 0.1 0.8 0.2 0.8 0.4 0.7 0.4 0.4 0.2 0.2 0.9 0.4 1.0 0.6 0.1 -0.1 -0.2 0.6 0.3 0.4 0.2 0.2 -0.1 1.8 0.9 1.1 0.8 0.7 0.7 0.4 -0.0 0.5 0.9 0.8 0.6
Risk taking 2.3 3.4 7.4 1.9 2.0 2.1 2.7 1.5 2.2 1.6 1.0 2.1 1.8 1.0 1.9 1.9 1.9 1.7 -1.9 0.9 2.1 2.0 2.0 2.0 2.1 2.5 2.2 2.2 1.8 2.1 0.5 2.4 2.1 2.0 2.0 2.0 2.1 2.0 1.7 2.1 1.8 1.5 -0.7 0.4 1.4 1.9 1.9 2.0 0.5 1.8 0.7 2.0 2.0
Ever had prostate specific antigen (PSA) test 0.2 0.3 1.0 0.7 0.3 0.1 0.6 0.6 0.4 0.8 0.7 -0.1 0.6 -0.4 0.4 0.4 -0.3 0.6 0.3 1.0 0.1 0.5 0.3 0.5 0.3 -0.1 0.1 0.1 0.6 0.2 0.4 0.8 0.1 0.1 -0.2 -1.0 0.2 -0.7 0.1 0.1 0.4 0.7 0.1 0.6 0.5 0.5 0.6 0.7 0.5 0.5 1.0 0.5 0.6
Fractured/broken bones in last 5 years 0.4 0.5 4.8 0.4 0.1 0.9 0.0 -0.1 -0.2 1.0 0.7 0.2 0.6 0.2 0.8 1.0 1.0 0.3 -1.1 -0.0 1.0 0.1 0.9 0.9 0.8 0.5 0.9 0.9 0.3 0.9 -0.2 0.4 1.0 0.7 0.6 2.2 0.9 0.7 0.9 0.9 0.1 -0.1 0.2 0.1 -0.2 0.3 0.5 -0.5 -0.3 0.9 -0.1 0.6 0.5
Age started oral contraceptive pill 2.8 3.5 8.1 -2.3 -1.9 -1.4 -1.5 -2.5 -2.1 -2.3 -2.8 -2.0 -2.3 -2.1 -1.9 -1.2 -0.3 -1.4 0.6 -2.1 -1.4 -2.0 -1.6 -1.6 -1.9 -2.0 -1.5 -1.5 -2.1 -1.7 -2.0 -2.1 -1.5 -1.0 -2.4 -0.5 -1.6 -0.8 -1.4 -1.4 -1.2 -2.6 0.3 -2.1 -2.6 -2.4 -2.3 -1.9 -2.0 -2.0 -2.1 -2.2 -2.3
Diastolic blood pressure, automated reading 0.9 2.8 11.1 2.1 1.0 0.6 0.7 2.1 1.7 2.4 3.3 0.5 2.0 2.7 0.9 0.5 -0.4 0.4 0.6 2.9 0.5 1.4 -0.0 1.3 1.2 0.4 0.6 0.6 1.9 0.9 3.0 2.1 0.9 -0.2 2.2 0.4 0.8 0.0 1.0 0.6 0.5 2.3 1.9 3.2 1.8 1.9 2.1 2.2 1.0 1.8 2.7 1.6 2.0
Ever depressed for a whole week 0.5 0.6 3.1 0.9 0.4 0.2 1.8 0.7 0.2 0.9 0.4 0.4 0.9 0.3 0.3 0.4 -0.4 0.3 0.2 1.4 0.2 0.4 0.2 0.8 0.6 0.1 0.3 0.2 0.6 0.4 1.3 1.0 0.4 -0.0 0.8 -0.4 0.2 0.1 0.6 0.2 0.0 1.3 0.2 1.2 0.6 1.1 1.1 1.7 0.6 0.9 1.3 0.8 0.7
Unable to work because of sickness or disability 2.3 3.0 8.4 2.1 1.6 1.4 2.0 2.1 1.7 2.2 1.3 1.7 2.2 1.6 1.8 1.4 0.5 1.2 -0.7 2.2 1.4 1.9 1.2 2.0 1.8 1.2 1.5 1.4 1.9 1.7 2.0 2.6 1.5 0.9 1.8 1.6 1.5 0.4 1.4 1.4 0.8 2.2 0.2 1.7 1.9 2.3 2.3 2.9 1.6 2.4 2.0 2.1 2.0
Commuting to job workplace: Cycle 1.4 1.7 6.9 -1.7 -1.3 -0.4 -1.1 -2.1 -1.3 -1.4 -0.7 -1.0 -1.8 -1.7 -1.3 -0.6 0.7 -1.1 -0.5 -2.3 -0.4 -1.9 -0.5 -1.2 -0.9 -0.7 -0.5 -0.4 -1.5 -0.7 -2.6 -1.7 -0.5 -0.1 -1.3 0.9 -0.7 -0.7 -0.7 -0.4 -1.1 -2.1 -0.5 -1.2 -1.7 -1.6 -1.6 -1.1 -1.6 -1.0 -2.2 -1.6 -1.6
Myopia 2.1 3.1 6.5 -1.9 -2.0 -1.9 -1.9 -1.8 -1.6 -1.8 -1.5 -1.7 -1.8 0.8 -1.9 -2.4 -1.7 -2.4 1.5 -0.9 -1.9 -2.3 -1.8 -2.4 -2.0 -2.2 -1.9 -1.9 -1.9 -2.0 -1.0 -1.6 -1.8 -2.0 -1.4 0.6 -2.0 -1.8 -1.8 -1.9 -2.6 -0.3 1.2 0.3 -1.6 -1.7 -1.7 -1.5 -1.5 -1.3 -0.9 -1.9 -1.9
Vascular/heart problems diagnosed by doctor 6.5 17.6 38.8 -5.3 -4.3 -2.6 -3.9 -6.2 -5.1 -5.1 -5.1 -4.2 -5.3 -3.6 -4.0 -2.3 -0.5 -2.5 0.5 -5.4 -2.6 -4.9 -2.7 -4.4 -3.8 -3.1 -2.9 -2.7 -5.3 -3.4 -6.1 -5.6 -2.8 -1.9 -4.8 -1.7 -3.2 -1.7 -2.6 -2.6 -2.9 -6.1 -0.5 -4.4 -5.6 -5.3 -5.1 -5.0 -4.8 -5.1 -5.4 -5.0 -5.2
Cholesterol lowering medication 5.0 7.3 11.8 3.2 3.0 2.5 2.7 3.0 2.3 2.7 2.4 3.1 3.3 1.1 2.9 2.4 1.9 2.6 -1.6 2.6 2.6 3.0 2.6 2.9 3.0 3.0 2.7 2.5 2.9 2.9 2.7 3.4 2.6 2.2 3.0 2.5 2.7 2.2 2.5 2.6 2.0 2.4 -1.1 1.5 3.2 3.4 3.2 2.9 2.7 3.3 2.5 3.3 3.1
Medication: Omeprazole (e.g. Zanprol) 5.7 6.9 11.0 2.6 3.1 3.0 3.2 2.4 2.1 3.0 2.2 3.2 2.7 2.2 2.9 2.8 2.5 2.7 -2.6 1.3 3.0 2.8 2.8 2.7 3.0 3.3 3.1 3.0 2.8 3.0 1.2 2.5 3.1 2.9 3.0 2.0 3.0 2.0 3.0 3.0 2.5 1.5 -1.9 0.9 2.6 2.9 2.6 2.7 2.2 2.7 1.1 2.9 2.7
Pain experienced in last month 2.8 4.7 8.3 -2.7 -2.2 -1.9 -2.3 -2.6 -2.7 -2.8 -2.9 -2.0 -2.6 -0.7 -2.5 -2.0 -0.8 -1.8 1.0 -2.1 -1.9 -2.6 -1.8 -2.6 -2.3 -2.0 -2.0 -2.0 -2.8 -2.2 -2.1 -2.6 -1.8 -1.3 -2.1 -1.5 -2.1 -0.9 -1.8 -1.9 -1.5 -2.6 -0.2 -2.0 -2.4 -2.6 -2.7 -2.5 -2.1 -2.6 -2.2 -2.5 -2.7
Supplements: Calcium 1.2 1.3 7.5 -1.1 -1.0 -0.0 -1.2 -2.1 -1.5 -1.1 -2.1 -1.5 -0.8 -2.3 -1.2 -0.1 0.5 -0.6 -0.8 -1.7 -0.0 -1.4 -0.1 -1.3 -0.4 -0.6 -0.2 -0.1 -1.1 -0.2 -1.5 -1.4 -0.0 0.0 -1.1 0.8 -0.3 -0.5 -0.0 -0.0 -0.3 -1.9 0.6 -1.6 -1.4 -1.2 -1.1 -2.7 -1.4 -0.4 -1.6 -0.7 -1.0
Basal cell carcinoma (self-reported) 2.0 2.4 5.7 -1.2 -1.8 -2.1 -1.4 -0.4 -1.0 -1.0 -0.3 -1.1 -1.2 -0.6 -1.8 -1.7 -2.0 -2.4 2.2 0.2 -2.1 -1.3 -1.9 -1.5 -1.8 -1.6 -2.0 -2.0 -1.1 -1.9 0.0 -1.3 -2.1 -2.2 -1.7 -0.5 -2.0 -2.4 -1.9 -2.1 -2.3 0.6 1.8 1.2 -1.0 -1.2 -1.2 -0.8 -1.4 -1.5 0.1 -1.4 -1.3
Heart attack/myocardial infarction (self-reported) 5.1 6.6 10.4 2.8 3.2 2.4 3.2 2.8 2.8 3.0 2.0 2.9 2.9 2.6 2.8 2.6 1.8 2.8 -1.6 2.0 2.4 3.1 2.6 2.8 2.7 2.8 2.5 2.4 2.6 2.6 1.8 2.8 2.4 2.5 2.6 0.7 2.5 2.5 2.3 2.4 3.1 1.9 -2.2 0.9 3.1 2.9 2.7 2.4 2.9 2.4 1.9 3.0 2.9
Deep venous thrombosis (DVT) (self-reported) 0.3 0.4 0.9 0.6 0.7 0.7 0.6 0.1 -0.0 0.6 0.6 0.9 0.6 0.4 0.7 0.9 0.6 0.8 -0.5 0.3 0.7 0.8 0.5 0.4 0.7 0.9 0.7 0.7 0.7 0.7 0.0 0.8 0.8 0.6 0.8 0.7 0.7 -0.3 0.7 0.7 0.3 0.4 -0.1 0.1 0.6 0.6 0.6 -0.3 0.0 0.1 0.3 0.6 0.5
Heart disease (siblings) 3.3 4.0 7.7 2.5 2.4 1.5 2.0 2.2 1.5 2.5 2.5 2.8 2.5 2.4 2.2 1.7 0.9 1.8 -0.5 2.6 1.5 2.1 1.6 1.9 2.1 2.2 1.7 1.5 2.0 1.8 2.6 2.6 1.5 1.6 2.4 0.4 1.6 1.4 1.5 1.5 1.7 1.8 -0.8 0.9 2.4 2.8 2.5 2.2 2.2 2.0 2.4 2.4 2.3
Alcohol drinker status: Previous 4.7 5.3 10.2 2.8 2.4 2.1 3.2 3.0 2.9 2.0 0.9 1.5 2.9 0.3 2.2 2.0 1.1 2.1 -1.2 2.3 2.1 3.1 2.4 2.9 2.5 2.1 2.1 2.1 2.8 2.4 2.5 3.2 2.1 1.8 1.9 0.9 2.3 1.7 2.0 2.1 2.4 2.3 -0.5 1.4 2.6 2.6 2.7 2.8 2.4 2.8 2.2 2.9 2.8
Pack years of smoking 1.0 1.5 3.6 0.9 1.7 1.4 1.1 1.1 1.2 1.1 1.4 1.9 1.1 0.8 1.5 1.1 1.4 1.3 -1.4 0.1 1.4 1.3 1.4 1.1 1.3 1.4 1.5 1.4 1.2 1.4 0.5 1.0 1.4 1.7 1.5 1.0 1.4 1.4 1.1 1.4 1.2 0.6 -1.0 0.2 1.4 1.1 0.9 0.6 1.5 1.1 -0.0 1.2 1.1
Impedance of whole body 0.3 1.6 13.4 -0.5 -1.0 -1.7 0.1 -0.1 -1.1 -0.5 -0.2 -1.7 -0.5 -1.6 -0.9 -1.0 -2.1 -1.1 2.0 1.1 -1.7 -1.0 -1.1 -0.4 -1.3 -1.7 -1.7 -1.7 -0.5 -1.5 1.4 0.0 -1.7 -1.4 -1.1 -3.7 -1.5 -1.3 -1.6 -1.7 -0.7 -0.0 1.4 1.0 -0.9 -0.5 -0.4 0.5 -0.1 -0.7 1.1 -0.8 -0.7
Leg fat mass (left) 1.5 5.7 14.7 2.4 2.9 2.5 1.6 2.2 2.5 2.4 2.5 3.6 2.5 1.9 2.4 1.8 2.1 2.0 -2.0 0.9 2.5 2.7 2.3 2.4 2.6 3.0 2.7 2.6 2.5 2.6 1.0 2.2 2.6 2.4 2.5 3.8 2.6 1.9 2.3 2.5 1.7 2.7 -2.0 1.0 2.7 2.7 2.4 2.1 2.0 2.3 1.1 2.6 2.5
Arm predicted mass (left) 0.1 0.5 5.2 -0.5 -0.6 -0.1 -0.5 -0.6 0.1 -0.5 -0.2 -0.1 -0.6 -1.3 -0.8 -0.6 0.2 -0.6 -0.1 -1.1 -0.1 -0.5 -0.3 -0.5 -0.3 0.1 -0.2 -0.1 -0.4 -0.3 -1.6 -1.0 -0.1 -0.3 -0.7 2.3 -0.3 -0.1 -0.2 -0.1 -0.8 0.8 0.4 1.2 -0.5 -0.5 -0.4 -0.9 -1.2 -0.9 -0.8 -0.5 -0.4