Best TWAS P=4.16e-08 · Best GWAS P=5.09e-06 conditioned to 0.00895
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | METAP2 | 0.11 | 0.07 | lasso | 3 | 0.05 | 0.0021 | 4.5 | -5.2 | 2.5e-07 | 0.39 | 0 | 0.21 | FALSE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | USP44 | 0.11 | 0.03 | blup | 66 | 0.03 | 0.0167 | -2.0 | 5.5 | 4.2e-08 | -0.39 | 0 | 0.05 | TRUE |