Best TWAS P=1.17e-07 · Best GWAS P=1.11e-07 conditioned to 0.049
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | SCFD1 | 0.12 | 0.11 | lasso | 2 | 0.10 | 8.5e-09 | 5.2 | -5.2 | 2.3e-07 | 0.69 | 0.01 | 0.98 | FALSE |
| 2 | GTEx | Colon Transverse | SCFD1 | 0.14 | 0.13 | lasso | 3 | 0.13 | 8.1e-07 | 5.2 | -5.2 | 2.0e-07 | 0.67 | 0.02 | 0.97 | FALSE |
| 3 | GTEx | Esophagus Mucosa | SCFD1 | 0.09 | 0.12 | enet | 11 | 0.11 | 1.0e-07 | 5.2 | -5.3 | 1.2e-07 | 0.76 | 0.03 | 0.97 | TRUE |
| 4 | GTEx | Skin Not Sun Exposed Suprapubic | SCFD1 | 0.14 | 0.05 | enet | 26 | 0.08 | 2.3e-05 | 5.2 | -5.3 | 1.5e-07 | 0.53 | 0.03 | 0.96 | FALSE |
| 5 | GTEx | Thyroid | SCFD1 | 0.10 | 0.08 | enet | 11 | 0.07 | 2.7e-06 | 4.9 | -5.2 | 2.0e-07 | 0.71 | 0.03 | 0.97 | FALSE |