Hub : Genes

SCFD1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1560	0.0330	1.3e-15	0.182	0.154	0.176	0.175	0.179	1.1e-21	2.4e-18	6.1e-21	9.5e-21	2.6e-21
2	GTEx	Adipose Subcutaneous	0.1170	0.0360	9.0e-06	0.106	NA	0.073	NA	0.103	5.7e-09	NA	1.5e-06	NA	8.5e-09
3	GTEx	Breast Mammary Tissue (Female)	0.0932	0.0754	1.4e-01	-0.010	NA	-0.006	NA	-0.010	9.9e-01	NA	5.2e-01	NA	8.5e-01
4	GTEx	Colon Transverse	0.1350	0.0460	4.1e-04	0.127	NA	0.098	NA	0.132	1.3e-06	NA	2.2e-05	NA	8.0e-07
5	GTEx	Esophagus Mucosa	0.0950	0.0280	9.3e-06	0.118	NA	0.109	NA	0.106	2.8e-08	NA	1.0e-07	NA	1.4e-07
6	GTEx	Muscle Skeletal	0.0627	0.0257	2.4e-03	0.045	NA	0.003	NA	0.023	3.0e-05	NA	1.5e-01	NA	2.1e-03
7	GTEx	Skin Not Sun Exposed Suprapubic	0.1390	0.0460	1.7e-04	0.049	NA	0.084	NA	0.076	1.1e-03	NA	2.3e-05	NA	5.8e-05
8	GTEx	Skin Sun Exposed Lower leg	0.0740	0.0320	3.9e-03	0.008	NA	0.018	NA	0.008	6.3e-02	NA	1.2e-02	NA	6.7e-02
9	GTEx	Thyroid	0.1020	0.0320	1.9e-05	0.078	NA	0.074	NA	0.069	1.4e-06	NA	2.7e-06	NA	5.3e-06
10	GTEx	Whole Blood	0.0870	0.0290	4.2e-05	0.071	NA	0.056	NA	0.075	4.3e-07	NA	6.3e-06	NA	2.1e-07
11	METSIM	Adipose	0.0636	0.0174	8.0e-08	0.054	0.049	0.053	0.048	0.052	1.6e-08	6.0e-08	2.0e-08	8.0e-08	2.7e-08
12	NTR	Blood	0.0172	0.0069	1.3e-03	0.016	0.009	0.010	0.008	0.012	5.2e-06	6.4e-04	1.9e-04	7.1e-04	5.4e-05
13	YFS	Blood	0.0462	0.0114	1.8e-15	0.045	0.053	0.054	0.051	0.054	1.7e-14	8.6e-17	3.5e-17	3.3e-16	4.1e-17
14	TCGA	Cervical Squamous Cell Carcinoma	0.0850	0.0430	1.5e-03	0.042	0.071	0.047	NA	0.030	3.9e-03	2.3e-04	2.4e-03	NA	1.3e-02
15	TCGA	Colon Adenocarcinoma	0.0440	0.0250	7.2e-03	0.020	0.020	-0.001	NA	0.007	2.3e-02	2.4e-02	3.8e-01	NA	1.3e-01
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0311	0.0185	5.3e-03	0.009	0.005	0.003	NA	0.003	2.7e-02	9.0e-02	1.5e-01	NA	1.5e-01
17	TCGA	Thyroid Carcinoma	0.0520	0.0220	1.1e-06	0.059	0.068	0.069	NA	0.064	2.1e-06	3.2e-07	2.9e-07	NA	8.2e-07

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.1	0.2	1.6	0.2	0.5	0.0	0.3	0.1	0.3	0.5	0.7	-0.1	0.3	0.2	-0.0	0.1	-1.3	-0.2	-0.1	0.1
Bipolar Disorder or Schizophrenia	0.1	0.3	0.8	-0.1	0.7	0.9	0.6	0.6	0.3	0.6	0.5	0.4	0.9	0.2	0.6	0.4	0.6	0.1	0.5	0.4
Depressed Affect (Nagel 2018)	2.0	4.2	6.5	2.2	-2.3	-0.5	-2.2	-2.4	-2.2	-2.2	-0.5	-1.8	-2.4	-2.1	-2.6	-2.2	-1.8	-1.8	-2.1	-2.1
Depression (Nagel 2018)	0.1	0.1	0.4	0.4	-0.4	-0.2	-0.3	-0.5	-0.3	-0.4	0.3	-0.1	-0.4	-0.4	-0.6	-0.3	-0.5	-0.2	-0.6	-0.1
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.7	0.9	-1.0	0.3	-1.2	-0.9	-0.6	-0.6	0.1	-0.7	-0.5	-1.0	-0.7	-1.1	-0.9	-1.6	-1.3	-0.7
Neuroticism (Nagel 2018)	3.0	7.1	9.1	2.8	-3.0	-0.4	-2.8	-3.0	-3.0	-3.0	-2.3	-2.5	-3.0	-2.8	-3.0	-2.5	-1.9	-2.1	-3.0	-2.9
Schizophrenia (2018)	0.2	0.4	2.5	-0.4	0.6	1.1	0.5	0.6	0.2	0.6	0.0	0.6	0.9	0.1	0.8	0.4	1.6	0.3	0.6	0.4
Schizophrenia vs Biploar Disorder	4.2	5.5	11.6	-2.6	2.2	0.7	2.3	2.6	1.7	2.4	1.0	2.1	2.5	2.4	2.8	2.2	3.4	2.4	2.6	2.5
Worry (Nagel 2018)	5.7	12.0	15.1	3.6	-3.7	-0.3	-3.7	-3.9	-3.5	-3.3	-3.3	-3.5	-3.7	-3.7	-3.7	-3.4	-2.8	-3.3	-3.9	-3.9
Alzheimer’s Disease (in mother)	0.2	0.3	1.9	0.1	-0.3	-1.4	-0.2	-0.1	-0.3	-0.5	-0.8	-0.6	-0.3	0.2	-0.3	-0.7	-0.5	0.1	-0.5	-0.3
Alzheimer’s Disease (in father)	3.2	3.5	5.3	1.9	-1.9	-1.2	-1.8	-2.0	-1.9	-2.1	-1.0	-2.3	-2.0	-1.8	-2.0	-2.2	-1.8	-1.7	-1.8	-1.8
Alzheimer’s Disease (including proxy)	2.1	3.0	5.3	1.5	-1.8	-2.1	-1.5	-1.6	-1.6	-2.0	-1.2	-2.3	-1.7	-1.1	-1.8	-2.2	-1.8	-1.2	-1.8	-1.6
Crohns Disease (2017)	0.9	1.9	3.5	1.4	-1.7	-0.6	-1.8	-1.5	-1.8	-1.4	-1.9	-1.3	-1.1	-1.4	-1.2	-1.2	-1.2	-1.3	-0.6	-1.3
Irritable Bowel Disease (IBD)	3.4	8.1	12.7	2.6	-3.4	-0.6	-3.6	-3.1	-3.6	-2.5	-2.2	-2.8	-2.5	-3.0	-2.6	-3.0	-3.0	-3.4	-2.3	-2.8
Ulcerative Colitis (UC)	3.5	6.6	11.0	2.2	-2.9	0.0	-3.2	-2.7	-3.1	-2.4	-1.5	-2.5	-2.2	-2.9	-2.3	-3.0	-2.7	-3.3	-2.5	-2.6
Major Depression (MDD)	0.4	0.5	1.4	0.9	-0.5	-0.0	-0.4	-0.6	-0.7	-1.2	-1.0	-0.9	-0.4	-0.7	-0.8	-0.5	-0.5	-0.4	-1.0	-0.8
Reaction Time	0.3	0.6	2.3	-0.9	0.6	0.1	0.8	0.8	0.5	-0.5	-1.5	0.7	0.9	0.8	0.6	0.8	0.1	0.8	0.5	0.8
Verbal and Numeric Reasoning (VNR)	0.6	1.4	2.2	-0.9	1.3	0.1	1.3	1.2	1.5	1.1	1.1	1.3	1.4	1.3	1.1	1.3	1.2	0.8	1.1	1.4
Breast Cancer	0.3	0.8	2.1	-0.9	1.0	-0.5	1.1	0.8	1.5	0.7	0.7	1.1	0.9	1.3	0.4	0.5	0.9	1.0	0.7	1.0
Ovarian Cancer	0.1	0.1	0.6	-0.2	-0.4	-0.8	-0.3	-0.2	-0.5	0.2	-0.4	0.0	-0.1	0.1	-0.2	-0.2	-0.2	0.0	0.3	-0.0
Prostate Cancer	0.3	0.4	1.7	0.9	-0.4	-0.1	-0.4	-0.8	-0.3	-0.4	-0.3	-0.8	-0.4	-0.4	-0.9	-0.6	-1.3	-0.7	-0.7	-0.4
Age at First Birth	0.8	1.1	3.8	-0.6	0.6	-0.6	0.6	0.8	0.7	2.0	-1.2	1.0	1.2	1.0	1.2	1.0	0.4	1.0	1.7	0.8
Bipolar Disorder (2011)	1.0	0.9	2.3	-0.9	0.9	-1.1	0.9	0.9	0.8	0.6	1.5	0.8	1.0	1.2	0.8	0.9	-0.2	1.0	0.9	1.1
Body Mass Index (BMI) (2010)	0.3	0.4	3.8	-0.0	-0.0	-1.9	0.5	0.2	-0.3	0.0	-0.8	-0.4	-0.1	0.6	-0.1	0.4	-0.7	1.2	0.4	0.2
Coronary Artery Disease (CAD)	0.7	0.8	1.6	-0.8	0.8	-0.9	0.9	0.9	0.9	1.0	1.3	0.9	0.9	1.2	0.8	0.8	0.0	0.9	0.6	0.8
Crohns Disease (2012)	0.1	0.1	0.4	0.2	-0.4	0.1	-0.4	-0.3	-0.6	0.1	-0.5	-0.1	-0.2	-0.4	0.0	0.3	-0.1	-0.2	0.5	-0.1
Mean Putamen Volume	1.8	2.0	10.5	-1.3	1.2	3.2	1.1	1.2	1.3	0.5	1.7	1.2	1.1	0.2	1.3	1.2	2.4	0.4	0.5	1.1
Fasting Glucose	0.2	0.2	0.5	-0.5	0.5	0.0	0.6	0.5	0.3	0.5	-0.6	0.4	0.5	0.7	0.4	0.7	0.5	0.4	-0.1	0.5
HbA1C	0.9	0.9	1.8	1.0	-1.1	-0.9	-0.8	-1.0	-1.3	-1.3	0.6	-1.2	-1.2	-0.4	-1.2	-0.8	-1.1	-0.2	-0.5	-0.7
HDL Cholesterol	0.5	0.8	3.9	-1.0	0.5	1.6	0.3	0.6	0.6	-1.2	2.0	0.9	0.8	0.3	0.6	-0.1	0.7	-0.2	0.1	0.6
LDL Cholesterol	1.2	2.0	3.3	1.2	-1.6	-1.8	-1.5	-1.3	-1.7	-0.8	-1.3	-1.4	-1.1	-0.8	-1.3	-1.6	-1.7	-1.3	-1.6	-1.4
Lupus	0.2	0.4	4.0	-0.0	0.5	0.9	0.3	0.2	0.6	-0.2	2.0	0.3	0.2	-0.2	0.2	0.1	0.1	-0.3	0.3	-0.1
Neuroticism (2016)	0.9	1.3	3.1	1.1	-1.2	0.7	-1.4	-1.3	-1.1	-1.8	0.3	-0.5	-1.2	-1.5	-1.2	-1.2	-0.1	-1.3	-1.3	-1.1
Primary Biliary Cirrhosis	0.9	1.3	2.4	-1.4	1.1	-0.3	0.8	1.3	1.1	1.2	0.9	1.3	1.6	1.4	1.6	0.9	0.2	0.7	1.4	1.3
Rheumatoid Arthritis	1.3	1.8	4.3	-1.3	1.3	-0.6	1.3	1.2	1.3	1.8	2.1	1.2	1.1	1.6	1.1	1.4	0.8	1.2	1.4	1.2
Schizophrenia (2014)	1.3	2.8	4.1	-1.6	1.8	0.9	1.8	1.8	1.4	1.7	1.2	1.6	2.0	1.6	1.9	1.8	2.0	1.5	1.6	1.8
Triglycerides	2.2	3.5	6.4	1.7	-2.0	-1.7	-2.0	-1.9	-2.0	-1.5	-2.5	-1.8	-1.9	-1.3	-1.9	-2.1	-2.1	-1.7	-1.8	-1.8
Type 2 Diabetes (T2D) (2012)	1.5	1.7	3.0	1.4	-1.4	0.2	-0.9	-1.4	-1.7	-1.6	-1.4	-1.7	-1.6	-1.4	-1.3	-0.7	-1.1	-0.9	-1.4	-1.3
Ulcerative Colitis	0.2	0.3	1.5	-0.1	-0.5	0.3	-0.8	-0.4	-0.5	-0.5	0.4	-0.3	0.0	-0.5	-0.1	-0.7	-1.2	-1.2	-0.2	-0.2
Blood Eosinophil Count	0.1	0.6	2.5	0.6	-0.8	1.6	-0.8	-0.7	-0.8	-0.4	0.7	-0.8	-0.6	-1.2	-0.3	-0.3	0.3	-0.6	0.0	-0.6
Blood Platelet Count	0.6	7.3	12.1	-2.8	2.8	0.3	2.9	2.8	3.0	3.2	1.8	3.5	2.7	3.0	2.5	2.9	2.0	2.7	2.5	3.0
Blood Red Count	0.0	0.2	2.1	-0.7	-0.1	1.5	-0.4	0.1	-0.1	-0.1	0.4	0.4	0.4	-0.2	0.6	0.2	0.5	-0.4	0.1	0.0
Blood White Count	0.5	3.4	6.4	-2.1	1.6	0.8	1.4	1.9	1.7	1.6	2.5	2.2	2.0	1.7	2.3	1.7	1.4	1.3	2.5	1.8
Heel T-Score	0.0	0.1	0.8	0.0	-0.4	-0.4	-0.5	-0.3	-0.5	-0.1	-0.5	-0.1	-0.2	-0.3	-0.2	-0.3	-0.9	-0.2	0.0	-0.4
BMI	1.4	8.3	12.8	-3.2	2.9	0.1	3.1	3.2	2.5	2.7	3.6	2.4	2.9	3.1	3.2	3.0	2.4	3.2	2.7	3.0
Height	2.3	43.5	54.2	7.1	-7.3	-1.9	-7.1	-7.4	-7.0	-6.1	-4.6	-7.4	-7.2	-7.0	-7.0	-6.5	-6.1	-6.4	-6.6	-7.1
Waist Hip Ratio (WHR)	0.4	1.7	3.4	1.0	-1.4	0.9	-1.7	-1.3	-1.4	-0.8	0.6	-1.8	-1.2	-1.7	-1.0	-1.6	-0.9	-1.7	-1.0	-1.3
Systolic Blood Pressure	0.5	2.5	5.1	1.2	-2.0	-0.8	-2.3	-1.8	-1.9	-1.8	-1.6	-0.5	-1.5	-1.4	-1.4	-1.9	-1.8	-1.8	-0.8	-1.3
Smoking Status	0.1	0.3	1.0	-0.6	0.3	-0.4	0.5	0.5	0.0	-0.2	0.4	0.0	0.3	0.4	0.6	0.6	0.6	0.7	1.0	0.5
Allergy or Eczema	0.8	2.0	4.0	1.5	-1.6	-1.6	-1.5	-1.6	-1.4	-0.9	-1.3	-1.7	-1.6	-1.0	-1.5	-1.2	-2.0	-0.9	-1.2	-1.3
Cardiovascular Disease	0.5	1.8	3.4	1.4	-1.7	0.5	-1.7	-1.6	-1.7	-0.6	-0.4	-1.2	-1.5	-1.8	-1.2	-1.4	-0.7	-1.4	-1.1	-1.7
Hypothyroidism (self reported)	0.1	0.2	0.5	-0.3	0.5	-0.0	0.5	0.4	0.4	0.1	0.0	0.5	-0.0	0.4	0.4	0.5	0.0	0.4	0.7	0.6
Respiratory disease	0.0	0.1	0.3	0.5	-0.2	-0.1	-0.4	-0.3	-0.4	0.5	-0.0	-0.4	-0.4	-0.2	-0.2	-0.0	0.2	-0.1	0.0	-0.2
Type 2 Diabetes (T2D) (2018)	0.2	0.4	1.7	-0.7	0.3	1.3	0.3	0.4	0.2	1.0	-0.0	0.6	0.4	0.1	0.5	0.8	0.8	0.2	0.5	0.5
Lung FEV1/FVC ratio	0.3	1.6	3.4	-1.5	1.2	-0.7	1.0	1.4	1.5	1.1	1.8	1.9	1.3	1.8	1.5	0.6	0.0	0.6	0.9	1.3
Lung FVC	0.3	1.4	3.2	1.1	-1.0	-0.8	-1.0	-1.1	-1.4	-1.8	-1.2	-1.5	-1.2	-0.8	-1.1	-1.2	-1.0	-1.4	-1.0	-0.9
Neuroticism	4.2	10.1	14.7	3.5	-3.4	-0.7	-3.2	-3.7	-3.3	-3.2	-2.6	-3.0	-3.6	-3.3	-3.8	-3.1	-2.6	-2.7	-3.5	-3.5
Chronotype (morning person)	0.1	0.3	0.7	0.6	-0.1	0.6	0.0	-0.4	-0.1	-0.5	-0.8	-0.5	-0.8	-0.5	-0.8	-0.7	0.2	-0.4	-0.8	-0.6
Hair Pigment	0.0	0.2	0.8	-0.6	-0.3	0.3	-0.1	0.3	-0.0	-0.1	0.9	0.2	-0.0	-0.3	0.7	0.9	0.5	0.6	0.6	0.2
Tanning	0.1	1.7	4.0	-0.8	1.4	-0.7	1.5	1.2	1.3	1.7	2.0	0.9	1.1	1.5	1.0	1.5	0.6	1.6	1.0	1.3
Hand grip strength (left)	0.4	1.0	2.3	1.3	-0.8	-0.6	-0.7	-1.2	-0.5	-1.5	0.2	-1.0	-1.2	-0.9	-1.5	-0.8	-1.1	-0.5	-1.3	-1.1
Number of treatments/medications taken	0.6	1.1	2.5	1.4	-1.5	-0.0	-1.2	-1.4	-1.6	0.1	-0.7	-0.9	-1.4	-1.5	-1.1	-0.5	-0.2	-0.3	-0.6	-1.3
Average weekly spirits intake	0.2	0.3	1.4	-0.3	0.6	-0.2	0.7	0.3	0.4	1.2	-0.3	-0.0	0.1	0.4	0.1	0.8	-0.3	0.9	0.7	0.2
Sensitivity / hurt feelings	0.4	0.6	1.5	1.2	-0.7	0.7	-0.6	-1.0	-0.6	-0.5	0.1	-0.7	-0.9	-1.1	-1.1	-0.4	-0.4	-0.5	-1.1	-1.0
Frequency of depressed mood in last 2 weeks	0.3	0.5	1.7	0.9	-0.7	-0.1	-0.6	-0.9	-0.6	-1.3	0.2	-0.7	-0.9	-0.6	-0.9	-0.5	-0.4	-0.5	-0.7	-0.4
Hearing difficulty/problems: Yes	0.3	0.4	1.1	0.1	-0.7	-1.1	-1.0	-0.4	-1.0	-0.8	-0.9	-0.5	-0.2	-0.2	-0.0	-0.7	-1.0	-0.4	0.1	-0.3
Relative age of first facial hair	0.3	0.6	4.6	0.0	-0.2	2.1	-0.6	-0.4	-0.2	0.4	-0.7	-0.1	-0.1	-0.8	-0.4	-0.8	0.2	-1.3	-0.9	-0.2
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	1.7	0.6	-0.8	0.6	-1.0	-0.7	-0.9	-1.3	-0.9	-0.9	-0.7	-0.9	-0.5	-1.2	-0.7	-1.1	-0.8	-0.8
Ever used hormone-replacement therapy (HRT)	2.0	2.6	5.3	-1.8	1.6	2.3	1.3	1.6	1.6	0.9	0.3	1.7	1.7	1.0	2.1	1.4	2.3	0.7	2.0	1.6
Ever had hysterectomy (womb removed)	7.9	8.9	11.8	-3.4	3.4	2.5	3.0	3.2	3.4	2.2	1.3	3.2	2.8	2.8	3.4	3.4	3.2	2.2	3.2	3.2
Systolic blood pressure, automated reading	0.1	0.3	0.8	0.1	-0.7	0.1	-0.9	-0.6	-0.7	-0.8	0.7	0.3	-0.6	-0.4	-0.3	-0.5	-0.7	-0.9	-0.2	-0.2
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	1.7	-0.8	0.9	-0.4	0.8	0.6	0.7	1.3	-0.1	0.6	0.6	1.0	0.6	0.8	-0.4	0.6	0.9	0.9
Angina	0.4	0.5	2.5	-0.4	0.2	-0.8	0.5	0.5	0.4	-0.3	1.1	0.7	0.5	0.5	0.6	0.6	1.6	1.0	0.2	0.3
Medication for hormone replacement therapy	1.5	1.7	3.4	1.1	-1.3	-1.6	-1.2	-1.2	-1.5	-1.8	-1.5	-1.1	-1.1	-0.8	-1.1	-1.1	-1.8	-1.0	-1.2	-1.1
Vitamin and mineral supplements	0.8	1.1	2.3	-1.1	1.4	-0.6	1.4	1.2	1.2	1.0	0.5	1.1	0.7	1.5	0.8	0.9	-0.3	1.0	0.9	1.4
Supplements: Zinc	0.6	0.6	3.6	0.7	-0.5	-0.9	-0.2	-0.5	-0.4	-0.2	-1.9	-1.1	-0.5	-0.3	-0.8	-0.7	-1.2	-0.1	-0.7	-0.5
Medication: Co-codamol	0.4	0.5	0.9	0.8	-0.7	-0.8	-0.6	-0.6	-0.9	-0.9	0.2	-0.7	-0.7	-0.4	-0.6	-0.8	-0.6	-0.6	-0.7	-0.5
Medication: Metformin	2.3	3.2	5.5	-2.3	1.4	0.5	1.5	1.9	1.5	1.7	0.7	1.9	2.3	1.6	2.1	2.3	1.9	1.7	1.9	2.2
Diabetes (father)	2.3	2.8	7.0	1.5	-1.4	-1.2	-1.5	-1.6	-1.4	-1.8	-0.2	-1.7	-1.4	-1.2	-1.8	-2.0	-2.3	-2.0	-2.7	-1.6
Diabetes (mother)	2.2	2.8	5.0	-2.0	1.5	0.1	1.5	1.9	1.4	2.1	1.7	1.5	2.2	1.6	2.1	1.5	0.7	1.6	1.9	1.7
Severe depression (siblings)	1.0	1.1	1.7	-0.9	1.3	0.6	1.3	1.3	1.3	0.4	-0.4	0.9	1.3	1.1	1.0	1.2	1.3	1.0	0.9	1.2
Pack years adult smoking proportion	0.6	0.8	3.8	-0.6	0.6	-2.0	0.6	0.8	0.3	1.0	-1.0	0.3	0.6	1.3	0.7	0.6	-0.8	1.0	1.1	0.9
Impedance of leg (right)	0.1	0.6	1.5	0.6	-0.6	1.1	-0.9	-0.7	-0.5	-0.6	0.4	-0.5	-0.5	-1.0	-0.6	-1.0	-0.2	-1.2	-0.6	-0.8
Leg fat-free mass (left)	0.4	2.1	3.9	1.2	-1.7	-1.1	-1.4	-1.5	-1.9	-2.0	-1.2	-1.9	-1.2	-1.3	-1.3	-1.1	-1.7	-1.0	-1.6	-1.4
Trunk fat percentage	0.5	1.9	8.9	-1.8	1.0	-0.4	1.1	1.4	0.7	0.6	3.0	0.8	1.6	1.3	1.6	1.1	0.8	1.5	1.2	1.4
Hand grip strength (right)	1.2	3.2	5.4	2.0	-1.7	-0.1	-1.7	-2.0	-1.5	-2.3	-1.5	-1.8	-1.7	-1.8	-2.1	-1.9	-1.5	-1.6	-2.2	-1.9
Townsend deprivation index at recruitment	0.2	0.3	1.7	0.3	-0.2	-0.0	-0.1	-0.3	-0.6	-0.4	-1.3	-0.9	-0.7	-0.3	-0.5	-0.1	-0.4	-0.2	-0.8	-0.3
Current tobacco smoking	0.1	0.2	0.4	0.2	-0.2	0.6	-0.3	-0.3	-0.4	-0.1	-0.4	-0.6	-0.5	-0.5	-0.3	-0.5	-0.2	-0.5	-0.3	-0.4
Average weekly fortified wine intake	0.3	0.4	1.7	0.4	-0.6	-1.3	-0.7	-0.5	-0.3	-0.2	0.6	0.0	-0.4	-0.1	-0.6	-1.0	-1.3	-0.4	-0.2	-0.5
Maternal smoking around birth	0.1	0.2	0.9	0.1	-0.1	0.2	-0.3	-0.3	-0.5	-0.8	-0.9	-0.2	-0.4	-0.4	-0.2	-0.4	0.2	-0.4	-0.2	-0.3
Fed-up feelings	0.1	0.2	0.7	0.2	-0.5	0.5	-0.2	-0.4	-0.6	-0.7	0.8	-0.0	-0.3	-0.4	-0.3	0.1	0.4	0.3	0.2	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.1	0.2	1.0	0.1	-0.1	0.2	-0.2	-0.3	-0.3	-1.0	-0.7	-0.2	-0.4	-0.1	-0.4	-0.6	-0.2	-0.5	-0.5	-0.1
Relative age voice broke	0.2	0.3	1.1	-0.7	0.7	0.7	0.4	0.4	0.8	1.0	0.7	0.8	0.5	0.5	0.3	0.3	-0.1	-0.2	-0.1	0.6
Taking other prescription medications	0.2	0.4	0.9	0.9	-0.5	0.1	-0.4	-0.7	-0.7	0.1	-0.8	-0.7	-0.8	-0.7	-0.8	-0.2	0.1	-0.2	-0.4	-0.6
Age when periods started (menarche)	0.1	0.3	1.8	0.1	-0.1	-1.3	-0.0	-0.1	-0.3	-0.1	1.3	-0.2	0.4	0.3	-0.2	-0.1	-0.5	0.3	-0.0	0.1
Bilateral oophorectomy (both ovaries removed)	0.9	1.0	3.4	-1.8	0.7	0.7	0.4	1.2	0.4	0.2	-0.2	1.8	1.3	0.9	1.6	0.7	0.4	0.3	1.3	1.1
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.1	3.6	1.4	-1.6	-0.5	-1.5	-1.4	-1.9	-1.4	-0.7	-1.8	-1.3	-1.5	-1.3	-1.6	-1.2	-1.4	-1.6	-1.7
Tinnitus: Yes, but not now, but have in the past	1.7	1.9	3.2	1.0	-1.4	0.3	-1.6	-1.2	-1.7	-1.7	-1.0	-1.5	-1.2	-1.3	-1.0	-1.7	-1.0	-1.7	-1.8	-1.3
Qualifications: CSEs or equivalent	0.1	0.1	0.6	0.2	-0.1	0.4	-0.0	-0.2	-0.1	-0.4	0.1	0.2	0.0	-0.3	-0.4	-0.1	0.4	-0.1	-0.8	-0.4
Serious illness, injury or assault to yourself	0.4	0.4	2.4	-0.5	0.6	-0.8	0.7	0.5	0.6	1.6	0.2	0.1	0.5	0.8	0.3	0.7	-0.6	0.6	-0.0	0.8
High blood pressure	0.1	0.4	2.1	0.0	-0.2	1.3	-0.2	-0.0	-0.0	1.2	1.4	0.4	-0.0	-0.5	0.2	0.5	0.6	-0.0	-0.1	-0.2
Hayfever, allergic rhinitis or eczema	0.7	1.5	9.2	1.1	-1.2	-3.0	-1.0	-1.0	-1.0	-0.7	-0.6	-1.1	-1.1	-0.2	-1.1	-1.0	-1.8	-0.1	-0.7	-0.9
Multivitamins +/- minerals	0.4	0.5	4.6	0.4	-0.3	2.1	-0.6	-0.5	-0.2	0.4	-0.5	-0.1	0.0	-0.9	-0.2	-0.4	0.5	-0.8	-0.0	-0.6
Stomach or abdominal pain in last month	0.3	0.3	1.2	0.4	-0.2	0.8	-0.2	-0.5	-0.3	-0.4	-0.9	-0.4	-0.4	-0.6	-0.7	-0.6	0.0	-0.4	-1.1	-0.6
Supplements: Glucosamine	0.0	0.1	0.3	-0.1	0.2	0.4	-0.1	-0.0	0.1	-0.4	-0.2	0.2	0.1	0.0	0.2	-0.2	0.0	-0.6	-0.3	-0.1
Diverticular disease/diverticulitis (self-reported)	0.8	1.0	2.2	1.4	-1.2	0.7	-0.9	-1.1	-1.0	-0.3	-0.0	-1.4	-1.4	-1.5	-0.9	-0.4	0.5	-0.5	-1.0	-1.0
Medication: Atenolol	0.0	0.1	0.6	0.3	-0.3	-0.8	-0.2	-0.1	-0.0	0.0	-0.1	0.1	-0.2	-0.0	-0.1	0.0	0.0	0.2	0.3	0.0
Medication: Levothyroxine sodium	0.1	0.2	0.9	-0.3	0.3	0.3	0.5	0.3	0.1	1.0	0.3	0.4	-0.1	0.2	0.3	0.7	0.2	0.7	0.7	0.4
Sitting height	2.3	16.2	21.0	4.2	-4.2	-1.0	-4.2	-4.5	-4.1	-4.1	-2.7	-4.6	-4.4	-4.2	-4.5	-3.8	-4.0	-4.0	-4.2	-4.2
Chronic bronchitis/emphysema (father)	0.2	0.2	0.9	0.1	0.6	0.4	0.7	0.4	0.4	0.5	-0.6	-0.1	0.0	0.3	0.3	0.4	0.9	0.9	0.5	0.2
High blood pressure (mother)	5.9	8.3	12.6	3.2	-2.9	-0.6	-3.0	-3.1	-2.7	-2.0	-1.0	-3.1	-3.4	-2.7	-3.3	-3.5	-2.8	-3.4	-3.5	-3.0
Body mass index (BMI)	1.2	5.2	7.4	-2.7	2.3	-0.1	2.5	2.6	1.9	1.8	2.5	2.0	2.6	2.5	2.6	2.5	1.8	2.6	2.0	2.6
Impedance of leg (left)	0.1	0.6	2.0	0.7	-0.6	1.4	-0.8	-0.8	-0.4	-0.8	0.4	-0.4	-0.6	-1.1	-0.7	-1.0	0.1	-1.2	-0.5	-0.8
Leg predicted mass (left)	0.4	2.0	3.7	1.1	-1.6	-1.1	-1.4	-1.4	-1.8	-1.9	-1.2	-1.8	-1.2	-1.2	-1.3	-1.1	-1.7	-1.0	-1.6	-1.3
Trunk fat mass	0.2	0.9	5.1	-1.2	0.5	-0.4	0.7	0.9	0.2	0.0	2.3	0.2	1.1	0.8	1.0	0.8	0.4	1.0	0.7	0.9
Waist circumference	0.2	0.9	3.0	-1.3	0.8	-0.0	1.0	1.0	0.6	0.4	1.7	0.2	1.1	0.9	1.0	1.0	0.5	1.0	0.5	1.1
Number of incorrect matches in round	0.2	0.3	0.9	-0.2	0.5	-0.2	0.6	0.3	0.7	-0.1	-0.5	0.4	0.4	0.6	0.2	0.8	0.2	1.0	0.9	0.7
Past tobacco smoking	0.0	0.1	0.3	0.1	0.3	-0.6	0.2	0.1	0.3	0.4	-0.3	0.5	0.1	0.4	-0.1	-0.2	-0.3	0.0	-0.2	-0.1
Alcohol usually taken with meals	0.1	0.2	1.2	-0.3	-0.2	-1.1	-0.2	0.0	-0.2	-0.9	-0.3	0.0	0.2	0.1	-0.0	-0.5	-0.2	-0.2	-0.0	0.0
Nervous feelings	4.0	7.5	10.6	2.8	-2.7	-0.2	-2.9	-2.9	-2.8	-2.6	-2.7	-2.6	-3.2	-2.8	-2.9	-2.9	-2.3	-2.8	-3.0	-3.0
Frequency of tenseness / restlessness in last 2 weeks	2.5	3.8	6.4	2.1	-2.0	-2.4	-1.9	-2.0	-1.9	-2.5	-2.1	-2.0	-2.0	-1.3	-2.1	-1.8	-1.6	-1.4	-2.3	-1.6
Hearing difficulty/problems with background noise	0.8	1.2	2.1	1.1	-1.3	-0.2	-1.5	-1.2	-1.3	-0.7	0.7	-1.0	-1.3	-1.1	-1.1	-1.2	-0.7	-1.2	-1.4	-1.0
Hair/balding pattern: Pattern 2	0.5	0.6	3.6	0.2	-0.8	0.3	-0.9	-0.6	-0.5	-1.9	1.0	-0.1	-0.5	-0.7	-0.3	-0.9	-0.1	-0.8	-0.3	-0.8
Had menopause	0.9	1.2	2.6	-1.5	1.0	0.6	0.6	1.2	1.2	1.2	1.1	1.1	1.2	1.0	1.6	0.8	0.9	0.3	1.1	1.1
Had other major operations	0.1	0.1	0.3	-0.4	0.2	-0.4	0.2	0.1	0.6	0.4	0.5	0.4	0.1	0.3	0.1	0.3	-0.4	0.3	0.3	0.2
Forced vital capacity (FVC)	4.3	16.4	20.8	4.5	-4.2	-0.7	-4.2	-4.6	-4.3	-4.0	-2.4	-4.4	-4.3	-4.2	-4.5	-4.0	-3.9	-4.3	-4.2	-4.3
Heel bone mineral density (BMD) T-score, automated (right)	0.6	1.4	2.3	1.1	-1.3	-0.9	-1.3	-1.1	-1.5	-1.1	0.3	-1.5	-1.0	-1.1	-0.9	-1.5	-1.5	-1.0	-1.3	-1.4
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.7	0.3	0.1	-0.3	0.3	-0.1	0.1	-0.3	0.4	0.1	-0.2	0.2	-0.3	0.4	-0.9	0.3	-0.2	-0.0
Qualifications: None of the above	2.3	4.9	9.7	-2.0	2.0	-0.1	2.3	2.1	1.8	1.6	2.4	2.0	1.9	2.2	2.2	3.1	2.1	2.7	2.8	2.5
Financial difficulties in last 2 years	0.9	1.2	2.1	0.9	-1.2	-0.4	-1.4	-1.1	-1.1	-1.2	0.1	-1.3	-0.7	-1.0	-1.0	-1.4	-1.1	-1.4	-1.4	-1.1
Mouth/teeth dental problems	3.6	5.5	8.8	-2.4	2.8	2.4	2.4	2.3	2.7	3.0	0.1	2.5	2.5	1.8	2.2	2.6	2.4	1.6	2.3	2.4
Heart attack	1.4	1.8	4.3	-1.2	1.0	-0.2	1.3	1.2	1.1	2.0	2.1	1.1	1.6	1.1	1.2	1.6	1.0	1.6	1.1	1.3
Allergy	0.2	0.4	2.4	0.2	-0.2	1.6	-0.4	-0.3	-0.3	-0.7	-0.5	-0.2	-0.2	-0.8	-0.3	-0.5	0.0	-1.0	-0.8	-0.4
Pain all over the body in last month	0.1	0.1	1.0	-0.3	0.0	-0.2	0.2	0.4	-0.1	0.1	-1.0	0.3	0.1	0.2	0.4	0.2	0.2	0.4	-0.0	0.2
Diabetes (self-reported)	2.4	3.7	6.0	-2.4	1.8	1.6	1.8	1.9	1.9	2.3	0.6	2.0	2.2	1.6	1.9	2.1	2.0	1.6	1.9	2.3
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	3.0	1.0	-1.3	-1.0	-1.4	-1.2	-1.6	-1.4	-1.7	-1.4	-1.2	-0.9	-1.0	-1.4	-1.3	-1.2	-1.2	-1.2
Medication: Ramipril	2.9	3.7	6.6	-2.2	1.6	1.5	1.8	2.1	1.3	1.6	0.9	2.0	2.0	1.4	2.4	2.3	2.6	2.0	2.2	1.9
Medication: Simvastatin	0.8	1.1	3.7	-0.7	0.9	0.8	1.1	0.9	0.8	1.9	0.2	0.8	0.8	0.6	0.9	1.7	1.4	1.1	0.8	1.1
Fluid intelligence score	0.5	1.1	4.3	-0.8	1.1	1.2	0.8	0.9	1.2	1.1	2.1	1.3	1.0	0.6	0.8	0.7	1.1	-0.0	0.6	0.8
Illnesses of siblings	2.2	3.1	7.1	1.7	-1.6	0.5	-1.6	-1.8	-1.7	-1.2	-2.0	-1.8	-1.6	-1.9	-1.9	-1.5	-1.7	-2.4	-2.7	-1.6
Neuroticism score	5.8	12.0	16.4	3.7	-3.6	-1.3	-3.4	-3.8	-3.7	-3.8	-2.7	-3.6	-3.8	-3.3	-4.0	-3.4	-3.1	-3.0	-3.9	-3.7
Weight	0.0	0.2	0.8	-0.4	-0.2	-0.5	-0.0	0.0	-0.5	-0.7	0.9	-0.5	0.2	0.0	0.2	0.2	-0.3	0.2	-0.2	0.2
Impedance of arm (right)	1.2	5.7	8.3	2.3	-2.8	-0.9	-2.8	-2.6	-2.5	-2.1	-0.7	-2.5	-2.5	-2.5	-2.5	-2.9	-2.2	-2.5	-2.3	-2.7
Arm fat percentage (right)	0.5	1.8	5.8	-1.9	1.1	-0.5	1.2	1.5	0.6	0.7	2.4	0.8	1.7	1.5	1.6	1.2	0.7	1.5	1.1	1.5
Trunk fat-free mass	0.6	3.5	5.0	1.8	-2.0	-0.8	-1.8	-2.0	-2.1	-2.1	-1.7	-2.2	-1.8	-1.8	-2.0	-1.5	-2.1	-1.7	-2.1	-1.8
Hip circumference	0.1	0.3	1.2	0.1	-0.4	-1.1	-0.2	-0.3	-0.7	-1.0	0.3	-0.9	-0.3	-0.1	-0.4	-0.4	-0.7	-0.1	-0.9	-0.3
Time employed in main current job	0.3	0.4	3.3	-0.3	0.3	1.8	0.1	0.0	0.5	0.6	0.5	0.3	-0.2	-0.4	0.1	0.2	1.1	-0.4	-0.3	0.2
Alcohol intake versus 10 years previously	0.7	1.1	6.9	-1.1	0.7	-0.1	0.6	0.9	0.9	1.2	2.6	1.0	1.1	1.0	1.0	0.8	0.2	0.3	0.4	0.7
Father’s age at death	1.0	1.4	2.8	-1.2	1.2	-0.8	1.2	1.1	1.1	1.7	-0.6	1.2	1.2	1.6	1.0	1.3	-0.5	0.9	1.3	1.4
Worrier / anxious feelings	7.8	14.8	21.5	4.0	-4.0	-0.2	-4.0	-4.2	-3.9	-3.8	-2.7	-4.1	-3.9	-4.1	-4.2	-3.9	-3.5	-4.0	-4.6	-4.2
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.2	0.6	0.1	-0.5	0.3	-0.7	-0.5	-0.5	-0.2	0.8	-0.2	-0.4	-0.5	-0.2	-0.7	-0.7	-0.8	-0.4	-0.4
Falls in the last year	1.8	2.4	4.9	-1.9	1.4	2.2	1.1	1.6	1.2	1.0	0.7	1.5	2.0	0.9	2.1	1.4	2.1	1.0	1.6	1.3
Hair/balding pattern: Pattern 3	0.1	0.2	0.8	0.6	-0.4	-0.4	-0.2	-0.3	-0.4	0.6	-0.4	-0.3	-0.9	-0.4	-0.2	-0.2	0.5	0.4	0.4	-0.6
Number of live births	1.3	1.9	4.0	1.9	-1.0	1.4	-1.0	-1.7	-0.6	-0.4	-0.4	-1.3	-1.5	-1.8	-2.0	-0.9	-0.5	-1.6	-2.0	-1.4
Forced expiratory volume in 1-second (FEV1)	2.8	9.4	12.0	3.4	-3.2	-0.9	-3.2	-3.5	-3.1	-2.8	-1.7	-3.2	-3.3	-3.1	-3.5	-3.0	-3.2	-3.3	-3.4	-3.3
Pulse rate	0.2	0.4	1.2	-1.0	0.1	0.1	0.1	0.6	-0.1	-0.3	-0.6	0.6	0.6	0.3	1.0	0.8	0.6	0.5	1.1	0.8
Happiness	0.2	0.2	0.9	-0.7	0.4	0.9	0.3	0.3	0.3	-0.4	-0.3	0.6	0.3	0.3	0.3	0.5	0.6	0.1	0.4	0.8
Noisy workplace	3.6	4.4	6.8	-2.5	1.9	-1.6	2.0	2.4	1.5	1.9	1.4	2.1	2.1	2.6	2.6	2.2	1.0	2.6	2.6	2.0
Qualifications: A levels/AS levels or equivalent	0.6	1.3	5.3	0.8	-1.2	-0.8	-1.2	-0.9	-1.2	-0.9	-2.3	-0.9	-0.9	-0.8	-0.7	-1.3	-1.1	-0.9	-0.8	-1.3
Serious illness, injury or assault of a close relative in last 2 years	0.1	0.1	0.5	0.4	-0.1	-0.7	0.3	-0.2	-0.1	0.1	-0.3	-0.6	-0.4	-0.0	-0.4	0.1	0.2	0.6	-0.1	-0.4
Mouth/teeth dental problems: Dentures	0.2	0.4	2.3	0.7	-0.2	-1.1	0.1	-0.3	-0.1	-0.7	1.5	-0.7	-0.6	-0.2	-0.5	-0.2	-0.0	0.2	-0.5	-0.2
Asthma	0.1	0.3	1.2	-0.4	0.6	-0.3	0.4	0.6	0.5	0.5	1.1	0.5	0.4	0.6	0.5	0.3	0.7	0.1	0.1	0.7
Medication: Ibuprofen (e.g. Nurofen)	3.8	4.9	6.7	2.2	-2.2	0.6	-2.6	-2.4	-2.3	-1.4	-2.0	-2.3	-2.3	-2.5	-2.1	-2.4	-2.1	-2.6	-2.2	-2.4
Medication: Cholesterol lowering	0.6	0.9	2.3	-0.8	0.9	0.6	1.0	0.9	1.1	1.3	1.2	0.6	0.8	0.6	0.8	0.8	1.5	1.0	0.6	0.8
Depression (self-reported)	2.0	2.4	4.7	2.2	-1.3	1.4	-1.4	-1.8	-1.3	-0.6	-0.9	-1.9	-1.6	-2.0	-1.9	-1.5	-1.3	-1.8	-1.1	-1.8
Medication: Lansoprazole	0.3	0.3	2.2	0.1	-0.3	0.7	-0.1	-0.1	-0.6	1.5	-1.0	-0.1	-0.1	-0.4	0.1	0.8	0.3	0.4	0.4	-0.1
Prospective memory result	0.8	1.0	2.0	-1.1	0.9	0.9	1.1	1.1	0.5	0.8	0.3	0.9	1.1	0.8	1.1	1.0	1.2	1.4	1.2	0.9
Lung cancer (father)	0.0	0.0	0.1	-0.1	-0.0	-0.2	0.1	0.2	-0.1	0.3	0.0	-0.2	0.2	0.1	0.2	0.1	0.2	0.3	0.1	0.0
Illnesses of mother	1.6	2.0	4.8	-1.1	1.4	2.2	1.4	1.2	1.1	0.6	-1.6	1.4	1.5	0.6	1.2	2.1	1.7	1.1	1.4	1.4
Forced expiratory volume in 1-second (FEV1), Best measure	4.2	13.4	17.8	3.9	-3.7	-0.7	-3.8	-4.0	-3.6	-3.6	-2.2	-3.6	-3.8	-3.7	-3.9	-4.0	-3.8	-4.2	-4.2	-3.9
Pulse wave Arterial Stiffness index	0.2	0.2	1.1	0.1	-0.2	1.1	0.1	-0.0	0.1	-0.3	-0.4	-0.1	-0.3	-0.4	0.1	0.7	0.8	0.4	0.4	0.1
Impedance of arm (left)	0.6	2.9	5.3	1.7	-2.0	-0.3	-2.2	-1.9	-1.9	-1.7	-0.3	-1.6	-1.8	-1.8	-1.7	-2.3	-1.3	-1.9	-1.5	-1.9
Arm fat mass (right)	0.2	1.0	3.0	-1.5	0.8	-0.4	0.9	1.1	0.4	0.4	1.7	0.4	1.3	1.1	1.2	1.0	0.4	1.1	0.7	1.1
Trunk predicted mass	0.6	3.3	4.9	1.8	-1.9	-0.8	-1.7	-2.0	-2.0	-2.0	-1.6	-2.2	-1.7	-1.8	-2.0	-1.4	-2.1	-1.6	-2.1	-1.8
Standing height	2.3	22.8	28.1	4.8	-5.2	-1.2	-5.2	-5.3	-5.1	-5.3	-3.4	-5.2	-4.8	-5.0	-5.1	-4.8	-4.5	-5.0	-4.8	-5.0
Length of working week for main job	1.3	1.5	3.7	-0.6	1.4	-1.9	1.5	1.0	1.4	1.5	1.0	0.6	0.8	1.8	0.5	1.1	-1.0	1.3	1.0	1.0
Exposure to tobacco smoke at home	0.3	0.4	1.2	-0.6	0.3	-0.3	0.2	0.6	0.3	-0.5	0.9	0.5	0.4	0.5	0.8	0.4	1.1	0.7	0.6	0.5
Breastfed as a baby	1.7	2.1	3.0	1.6	-1.7	-0.7	-1.7	-1.6	-1.7	-1.7	-0.4	-1.5	-1.6	-1.4	-1.2	-1.6	-1.3	-1.3	-1.0	-1.7
Tense / ‘highly strung’	1.0	1.6	3.2	1.2	-1.0	-0.1	-1.1	-1.2	-1.0	-1.8	-1.7	-1.2	-1.2	-1.1	-1.3	-1.4	-1.0	-1.2	-1.6	-1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	2.4	3.7	6.4	1.9	-2.1	1.4	-2.2	-2.3	-2.0	-1.2	0.1	-1.9	-1.9	-2.5	-2.1	-1.7	-1.5	-2.5	-1.9	-2.0
Hair/balding pattern: Pattern 4	0.7	1.8	2.9	-1.5	1.7	-0.2	1.6	1.5	1.6	1.6	0.6	1.5	1.6	1.7	1.2	1.1	0.5	1.2	0.9	1.5
Birth weight of first child	0.9	1.6	2.5	1.3	-1.5	0.6	-1.5	-1.5	-1.4	-1.1	-0.5	-1.4	-1.1	-1.6	-1.4	-1.0	-0.9	-1.5	-1.4	-1.3
Peak expiratory flow (PEF)	1.1	2.6	3.8	1.7	-1.8	-1.8	-1.6	-1.8	-1.7	-1.1	-1.0	-1.8	-1.7	-1.3	-1.8	-1.1	-1.8	-1.3	-1.9	-1.6
Pulse wave reflection index	0.1	0.2	0.5	0.5	-0.3	0.4	-0.3	-0.5	0.0	0.2	-0.1	-0.6	-0.7	-0.6	-0.5	0.0	-0.2	-0.4	-0.5	-0.5
Ever highly irritable/argumentative for 2 days	0.2	0.2	0.7	-0.5	0.5	-0.2	0.6	0.5	0.3	-0.5	0.8	0.4	0.3	0.7	0.3	0.5	0.3	0.4	-0.5	0.3
Loud music exposure frequency	0.4	0.4	2.8	-0.3	0.0	1.7	-0.4	-0.1	-0.2	-1.3	-0.4	0.2	0.2	-0.5	0.2	-0.6	0.4	-1.0	-0.3	-0.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.5	0.1	-0.5	-0.9	-0.5	-0.2	-0.2	-1.1	-0.4	-0.1	-0.1	-0.0	-0.3	-1.2	-0.7	-0.7	-1.2	-0.4
Mouth/teeth dental problems: Bleeding gums	3.4	4.4	9.8	1.4	-2.5	-2.8	-2.5	-1.9	-2.8	-2.3	-1.6	-1.8	-1.5	-1.2	-1.6	-2.2	-3.1	-1.5	-2.0	-1.9
Blood clot in the leg (DVT)	3.1	4.0	5.8	-2.4	1.7	0.8	1.9	2.1	1.8	2.2	0.7	1.9	2.4	1.8	2.2	2.3	2.2	2.1	2.4	2.1
Medication: Paracetamol	0.4	0.7	2.0	1.4	-0.8	-0.1	-0.5	-1.0	-0.9	-0.3	0.3	-1.3	-0.9	-1.0	-1.1	-0.7	-0.0	-0.4	-0.6	-0.9
Headache pain in last month	0.4	0.6	2.2	-0.7	0.7	-0.4	0.6	0.6	0.8	1.2	1.5	0.7	0.8	0.9	0.6	0.3	0.3	0.8	0.9	0.6
Medication for cholesterol, blood pressure or diabetes	0.2	0.3	1.8	-0.1	0.4	-1.4	0.2	0.2	0.3	0.0	-0.2	0.3	0.1	0.8	0.1	-0.0	-1.2	-0.0	0.1	0.4
Glaucoma (self-reported)	1.6	1.8	3.3	-1.4	1.6	0.4	1.5	1.5	1.6	1.2	0.9	1.4	1.3	1.3	1.4	0.9	1.3	1.4	1.8	1.3
Gout (self-reported)	1.2	1.6	4.8	1.1	-1.6	-1.0	-1.5	-1.3	-1.5	-2.2	1.0	-1.3	-1.1	-1.2	-1.1	-1.2	-1.1	-1.0	-0.7	-1.1
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	1.4	-0.5	0.9	-0.4	1.2	0.8	0.8	1.1	-0.1	0.9	0.3	1.0	0.7	1.1	0.1	1.2	1.0	1.0
Medication: Amlodipine	1.0	1.3	7.5	1.5	-0.8	-0.7	-0.7	-1.1	-1.0	0.2	-2.7	-1.4	-1.6	-0.8	-1.2	-0.4	-0.9	-0.3	-0.7	-1.1
Medication: Ventolin 100micrograms inhaler	2.7	3.4	6.6	-1.7	2.0	0.9	2.1	1.8	1.8	2.6	1.0	1.7	1.8	1.7	1.7	2.4	1.7	1.9	2.0	2.0
Birth weight	1.5	3.2	4.9	2.0	-1.9	-0.6	-1.7	-1.9	-2.0	-2.2	-2.2	-1.8	-1.8	-1.8	-2.0	-1.2	-1.8	-1.4	-1.7	-1.8
Chronic bronchitis/emphysema (mother)	0.8	0.9	1.7	1.0	-1.0	-0.7	-1.2	-1.2	-0.8	-0.3	0.1	-0.8	-1.3	-1.0	-1.1	-1.0	-0.9	-1.0	-0.8	-1.1
High blood pressure (siblings)	0.1	0.1	0.7	-0.2	0.2	-0.3	0.2	0.2	0.3	-0.3	0.9	0.4	0.1	0.3	0.2	0.2	0.3	0.3	0.2	0.2
Forced vital capacity (FVC), Best measure	5.4	19.6	24.0	4.8	-4.5	-0.7	-4.7	-4.9	-4.6	-4.4	-2.9	-4.6	-4.6	-4.6	-4.8	-4.7	-4.2	-4.9	-4.7	-4.8
Body fat percentage	0.8	3.2	10.3	-2.3	1.5	-0.2	1.6	1.9	1.1	0.9	3.2	1.3	2.1	1.8	2.1	1.5	1.3	1.9	1.6	1.9
Leg fat percentage (right)	2.2	7.9	12.0	-3.5	2.7	0.8	2.8	3.1	2.4	2.1	3.5	2.5	3.3	2.8	3.3	2.8	2.5	2.8	2.7	3.1
Arm fat-free mass (right)	0.1	0.3	1.0	0.5	-0.5	-0.0	-0.3	-0.6	-0.6	-1.0	-0.5	-0.8	-0.4	-0.6	-0.6	-0.1	-0.7	-0.4	-0.8	-0.4
Exposure to tobacco smoke outside home	1.0	1.3	2.6	-1.4	1.4	-0.5	1.3	1.3	1.4	0.8	0.5	1.3	1.5	1.6	1.1	0.6	0.7	1.0	0.7	1.3
Comparative body size at age 10	0.2	0.6	3.0	-0.9	0.4	-1.1	0.5	0.8	-0.1	-0.0	-1.7	0.7	0.8	0.9	0.9	0.6	-0.2	0.6	0.3	0.8
Number of full brothers	0.4	0.5	2.4	0.5	0.1	-1.6	0.1	-0.3	0.5	1.1	0.9	-0.4	-0.3	0.3	-0.7	-0.6	-1.2	-0.0	-0.4	-0.1
Worry too long after embarrassment	0.8	1.4	3.7	1.0	-1.1	-0.1	-1.2	-1.1	-1.4	-1.6	-1.9	-0.7	-1.1	-0.9	-1.0	-1.3	-0.6	-1.2	-1.4	-1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	4.3	1.9	-1.3	0.0	-1.0	-1.7	-1.0	-1.6	-1.0	-1.6	-1.9	-1.6	-2.1	-1.0	-1.0	-1.0	-1.9	-1.5
Wheeze or whistling in the chest in last year	0.0	0.1	0.9	-0.0	-0.0	-0.2	-0.0	0.1	-0.0	0.2	1.0	-0.4	0.1	0.2	0.1	0.2	-0.0	0.1	-0.3	0.2
Number of children fathered	2.5	2.8	4.8	2.0	-2.1	-0.1	-1.9	-2.0	-1.8	-0.9	-0.4	-1.6	-1.8	-2.2	-1.9	-1.2	-1.2	-1.4	-2.0	-2.1
Reason for reducing amount of alcohol drunk: Health precaution	6.8	7.9	11.7	3.1	-2.8	1.4	-2.9	-3.1	-2.9	-2.0	-2.4	-2.8	-3.0	-3.3	-3.1	-2.5	-2.5	-3.4	-3.0	-2.9
Age at first live birth	0.2	0.3	2.8	0.3	-0.5	-0.7	-0.3	-0.2	-0.5	0.3	-1.7	-0.3	-0.1	-0.1	0.1	-0.4	-0.7	0.0	0.5	-0.5
Pulse wave peak to peak time	0.2	0.2	0.9	0.1	-0.0	-0.9	-0.3	-0.2	-0.3	-0.0	0.4	-0.1	0.1	0.2	-0.3	-0.9	-0.9	-0.6	-0.5	-0.3
Health satisfaction	0.2	0.3	1.4	-0.7	0.1	0.8	0.1	0.4	0.2	-0.3	1.2	0.4	0.3	0.0	0.7	0.3	1.0	0.4	0.4	0.3
Shortness of breath walking on level ground	0.3	0.3	0.9	0.1	-0.7	-1.0	-0.6	-0.3	-0.7	-0.9	0.6	-0.1	-0.2	-0.2	-0.2	-0.8	-1.0	-0.2	-0.5	-0.4
Qualifications: College or University degree	1.2	3.7	8.6	1.8	-1.9	-0.5	-2.2	-1.9	-2.0	-1.3	-2.9	-1.9	-1.6	-1.8	-1.8	-2.4	-1.8	-2.4	-1.4	-1.8
Eye problems/disorders: None of the above	0.3	0.4	2.0	0.3	-0.3	-0.2	-0.4	-0.3	-0.2	-1.4	-0.4	-0.4	-0.3	-0.1	-0.4	-0.6	-0.8	-1.0	-1.1	-0.3
Mouth/teeth dental problems: Loose teeth	0.9	1.1	14.3	0.2	-0.2	-3.8	0.0	-0.1	-0.1	0.7	0.8	-0.3	-0.4	1.0	-0.2	0.0	-1.2	0.8	0.1	0.0
Emphysema/chronic bronchitis	0.4	0.4	3.0	0.2	0.5	-0.2	0.7	0.4	0.7	0.8	1.7	0.1	-0.1	0.4	0.4	0.9	0.2	0.8	0.9	0.2
Medication for pain relief, constipation, heartburn	0.6	1.0	2.2	-1.4	1.1	-0.9	1.1	1.3	1.0	0.1	-0.1	1.2	1.1	1.5	1.1	0.8	-0.1	0.9	0.9	1.2
Neck or shoulder pain in last month	0.1	0.2	1.4	0.2	0.3	1.1	0.3	-0.1	0.1	0.3	1.2	-0.2	-0.2	-0.2	-0.1	0.4	0.5	0.3	0.4	0.1
Medication: Blood pressure	0.3	0.5	2.2	0.3	-0.8	1.5	-0.7	-0.6	-0.9	-0.6	-0.3	-0.5	-0.4	-1.1	-0.4	-0.4	0.8	-0.3	-0.5	-0.7
Angina (self-reported)	0.3	0.4	2.5	-0.3	0.1	-0.7	0.4	0.5	0.3	-0.4	1.1	0.6	0.5	0.4	0.6	0.5	1.6	1.0	0.3	0.2
Migraine (self-reported)	0.1	0.1	0.6	0.3	-0.2	0.7	-0.3	-0.2	0.0	-0.8	-0.2	-0.0	-0.4	-0.5	0.0	-0.5	0.4	-0.5	-0.0	-0.3
Medication: Ibuprofen	3.9	4.7	5.8	2.1	-2.2	0.2	-2.4	-2.3	-2.2	-0.8	-2.2	-2.3	-2.4	-2.3	-2.1	-2.3	-2.2	-2.4	-2.4	-2.4
Medication: Allopurinol	0.4	0.5	2.0	0.5	-0.9	-0.2	-0.9	-0.8	-0.9	-1.4	0.7	-0.8	-0.7	-0.8	-0.6	-0.8	-0.4	-0.7	-0.3	-0.5
Medication: Omeprazole	0.1	0.1	0.6	-0.2	-0.4	0.1	-0.3	-0.0	-0.3	0.0	0.8	0.3	0.2	-0.1	0.5	0.5	0.7	0.1	0.3	0.1
Medication: Seretide 50 evohaler	1.5	1.7	3.1	-1.1	1.2	0.6	1.3	1.2	1.1	1.4	1.2	1.4	1.2	1.0	1.1	1.6	1.8	1.5	1.7	1.2
Mean time to correctly identify matches	0.6	1.1	2.1	-1.3	0.8	-1.0	1.0	1.2	0.8	-0.4	-0.6	1.1	1.2	1.5	1.1	1.0	0.3	1.4	1.2	1.3
Heart disease (mother)	0.5	0.6	3.6	0.4	-0.7	-1.1	-0.5	-0.6	-0.5	-1.9	0.8	-0.5	-0.6	-0.3	-0.6	-0.7	-0.8	-0.4	-0.8	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.1	0.4	0.1	-0.1	-0.1	0.2	-0.1	0.1	0.6	-0.1	-0.3	-0.2	-0.2	-0.4	0.1	0.5	0.4	-0.3	-0.1
Whole body fat mass	0.5	1.9	5.6	-1.9	1.1	-0.3	1.3	1.5	0.7	0.5	2.4	0.9	1.7	1.4	1.6	1.3	0.9	1.5	1.2	1.5
Leg fat mass (right)	0.9	3.5	6.2	-2.5	1.7	0.5	1.8	2.1	1.3	1.0	2.4	1.5	2.3	1.8	2.3	2.0	1.6	1.9	1.8	2.1
Arm predicted mass (right)	0.1	0.3	1.5	0.3	-0.5	-0.0	-0.4	-0.5	-0.6	-1.2	-0.6	-0.7	-0.3	-0.5	-0.5	-0.1	-0.6	-0.5	-0.7	-0.3
Pulse rate, automated reading	0.2	0.7	1.6	-0.9	1.0	0.5	0.9	0.8	1.0	0.4	0.2	0.7	0.7	0.9	0.8	1.1	0.3	0.6	1.3	1.1
Alcohol intake frequency.	0.2	0.5	1.8	-0.8	0.7	0.5	0.6	0.6	0.8	0.2	1.3	0.8	0.7	0.5	0.6	0.6	0.9	0.4	0.3	0.6
Comparative height size at age 10	2.2	12.0	16.2	3.5	-3.7	-0.9	-3.5	-3.8	-3.8	-3.7	-2.8	-4.0	-3.7	-3.6	-3.8	-3.2	-3.2	-3.4	-3.5	-3.5
Number of full sisters	0.1	0.1	0.5	-0.0	0.1	0.6	-0.2	-0.1	0.1	0.3	-0.0	-0.0	0.2	-0.1	0.1	-0.4	-0.2	-0.2	0.7	-0.1
Suffer from ‘nerves’	1.3	2.0	2.7	1.4	-1.7	-0.5	-1.7	-1.6	-1.6	-1.0	-1.0	-1.2	-1.4	-1.5	-1.6	-1.5	-1.3	-1.4	-1.5	-1.4
Overall health rating	0.2	0.4	3.1	-0.5	0.2	1.0	0.4	0.3	-0.1	0.7	1.8	0.2	0.3	0.0	0.5	0.6	0.8	0.5	0.4	0.4
Chest pain or discomfort	0.2	0.3	1.7	-0.3	0.2	-1.3	0.2	0.3	-0.0	0.9	-0.2	0.1	0.4	0.7	0.4	0.0	-0.0	0.4	0.5	0.4
Had major operations	0.3	0.3	1.8	-0.3	-0.3	-1.4	-0.3	-0.1	-0.6	-0.2	-1.2	-0.2	0.1	0.2	0.1	0.2	-0.6	0.4	0.7	-0.2
Age at last live birth	0.6	0.9	2.5	1.3	-1.0	-1.4	-0.7	-1.1	-0.7	0.4	-0.8	-1.2	-0.9	-0.7	-1.1	-0.8	-1.6	-0.3	-0.3	-1.0
Family relationship satisfaction	1.2	1.5	2.7	-1.5	1.4	1.1	1.4	1.2	1.3	0.5	0.6	1.3	1.5	1.2	1.0	1.2	1.1	1.1	1.1	1.6
Leg pain on walking	0.2	0.2	1.3	-0.3	0.3	0.1	0.5	0.5	0.1	-0.4	1.1	0.2	0.4	0.3	0.6	0.4	0.7	0.6	-0.3	0.1
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	4.5	0.6	-0.7	2.1	-1.0	-0.8	-0.7	-0.7	-0.6	-0.7	-0.5	-1.5	-0.7	-1.1	0.2	-1.1	-1.1	-1.0
Commuting to job workplace: Car/motor vehicle	0.1	0.1	1.1	0.2	-0.2	0.2	-0.1	-0.1	-0.3	-1.1	0.4	0.2	-0.1	-0.4	0.1	-0.0	0.8	0.1	0.1	-0.3
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	0.6	0.7	-0.5	-0.1	-0.4	-0.6	-0.6	-0.5	-0.8	-0.5	-0.5	-0.6	-0.6	-0.5	0.0	0.0	-0.1	-0.7
Medication: Aspirin	0.9	1.2	2.7	-0.8	1.1	0.5	1.1	0.9	1.3	1.6	0.7	0.8	1.0	0.8	0.9	1.4	1.4	1.2	1.0	1.0
Supplements: Vitamin C	3.9	4.7	8.8	2.4	-2.5	-1.2	-2.2	-2.4	-2.3	-3.0	-1.0	-2.7	-2.2	-2.2	-2.3	-1.7	-0.9	-1.7	-2.4	-2.2
Knee pain experienced in last month	0.4	0.7	4.9	0.3	-0.5	2.2	-0.7	-0.6	-0.7	-0.1	0.8	-0.5	-0.5	-1.1	-0.3	-0.0	0.5	-1.0	-0.8	-0.4
Hypertension (Self-reported)	0.1	0.4	2.5	0.3	-0.4	1.6	-0.4	-0.3	-0.3	0.9	1.3	0.2	-0.3	-0.8	-0.0	0.3	0.5	-0.3	-0.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.1	2.7	1.2	-1.5	0.6	-1.3	-1.3	-1.4	-0.2	0.0	-1.0	-1.2	-1.6	-1.0	-0.4	-0.3	-0.7	-0.8	-1.2
Illnesses of father: Heart disease	0.7	1.0	2.3	1.0	-1.1	-1.5	-1.1	-0.9	-1.0	-0.8	0.5	-0.9	-1.0	-0.8	-0.8	-1.5	-1.1	-0.8	-0.9	-1.1
Illnesses of siblings: Diabetes	2.1	2.6	4.2	-1.4	1.6	0.4	1.7	1.7	1.6	1.7	0.8	1.6	1.8	1.6	1.6	2.0	1.8	2.1	1.9	1.5
Smoking status: Previous	0.1	0.2	0.5	0.3	-0.7	0.1	-0.6	-0.4	-0.7	-0.7	-0.6	-0.6	-0.5	-0.6	-0.2	-0.1	-0.1	-0.2	0.1	-0.2
Forced expiratory volume in 1-second (FEV1), predicted	5.7	11.8	19.6	3.2	-3.6	0.5	-3.8	-3.6	-3.5	-3.2	-2.2	-3.7	-3.2	-3.8	-3.3	-4.1	-2.9	-4.4	-3.9	-3.7
Whole body fat-free mass	0.5	2.9	4.5	1.5	-1.8	-1.0	-1.6	-1.8	-2.0	-2.1	-1.5	-2.1	-1.6	-1.6	-1.8	-1.3	-2.0	-1.4	-2.0	-1.6
Leg fat-free mass (right)	0.4	2.4	4.2	1.3	-1.7	-1.2	-1.5	-1.6	-1.8	-2.1	-1.4	-1.9	-1.4	-1.4	-1.5	-1.2	-1.7	-1.1	-1.7	-1.4
Arm fat percentage (left)	0.6	2.5	6.4	-2.2	1.3	-0.2	1.5	1.8	0.9	0.8	2.5	1.1	1.9	1.7	1.9	1.4	1.2	1.7	1.3	1.7
Average weekly red wine intake	2.0	2.9	6.2	1.8	-1.5	-0.3	-1.3	-1.6	-1.7	-2.0	-1.6	-2.1	-1.8	-1.6	-1.9	-1.6	-1.1	-1.8	-2.5	-1.6
Handedness (chirality/laterality): Left-handed	1.5	1.8	3.0	1.1	-1.3	-0.9	-1.3	-1.3	-1.2	-1.7	1.0	-1.5	-1.5	-1.2	-1.4	-1.7	-1.3	-1.0	-1.3	-1.6
Mood swings	4.5	8.1	11.7	3.1	-2.9	0.2	-2.9	-3.3	-2.9	-3.4	-0.2	-3.0	-3.2	-3.1	-3.4	-3.0	-1.9	-3.0	-3.0	-3.1
Loneliness, isolation	0.3	0.4	3.0	0.4	-0.3	0.2	-0.5	-0.5	-0.3	-1.7	-0.7	-0.4	-0.5	-0.2	-0.6	-0.9	-0.4	-0.8	-0.6	-0.2
Long-standing illness, disability or infirmity	1.3	2.0	3.9	-1.6	1.2	0.8	1.2	1.6	1.0	2.0	1.1	1.4	1.5	1.2	1.8	1.4	1.4	1.5	1.8	1.3
Ever had bowel cancer screening	0.5	0.5	1.6	0.7	-0.8	0.3	-0.7	-0.7	-0.9	-1.2	-0.5	-0.9	-0.7	-0.9	-0.6	-0.7	-0.6	-0.4	-0.5	-0.8
Diabetes diagnosed by doctor	1.9	3.1	5.4	-2.1	1.6	1.1	1.6	1.7	1.7	2.3	0.8	1.8	1.9	1.4	1.7	2.2	1.9	1.5	1.8	2.1
Ever had stillbirth, spontaneous miscarriage or termination	1.7	1.8	3.9	1.2	-1.5	-1.6	-1.3	-1.2	-1.5	-2.0	-1.1	-1.3	-1.0	-1.0	-1.3	-1.7	-1.1	-0.9	-1.4	-1.3
Friendships satisfaction	0.2	0.3	2.7	-0.1	-0.6	-0.4	-0.6	-0.3	-0.7	-1.6	-0.1	-0.3	0.1	-0.3	-0.3	-0.4	-0.3	-0.4	-0.6	0.0
Qualifications: nursing, teaching	1.0	1.6	3.2	1.0	-1.3	-0.9	-1.4	-1.2	-1.3	-1.0	-1.5	-1.2	-1.0	-1.0	-1.1	-1.8	-1.5	-1.4	-1.2	-1.3
Commuting to job workplace: Walk	0.9	1.0	2.0	-1.2	1.2	0.5	0.8	1.0	1.2	0.6	1.4	1.2	1.2	1.2	1.0	0.5	0.6	0.6	1.0	1.2
Eye problems/disorders: Cataract	0.9	1.0	2.0	-0.7	0.8	-0.1	0.9	0.9	0.8	1.4	0.6	0.9	0.9	0.9	0.9	1.2	1.0	1.4	1.4	1.1
Mouth/teeth dental problems: Mouth ulcers	2.1	3.3	5.3	2.3	-1.9	-0.4	-1.7	-2.0	-1.8	-2.1	-0.3	-2.0	-2.1	-1.9	-2.1	-1.8	-1.3	-1.3	-2.1	-2.2
Medication for cholesterol	0.1	0.1	0.3	0.1	0.2	-0.0	0.1	0.0	0.4	-0.3	0.6	-0.3	-0.1	0.1	-0.1	-0.5	0.5	-0.1	-0.0	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	4.0	-0.3	0.7	2.0	0.6	0.5	0.8	0.3	1.4	0.6	0.3	-0.1	0.4	0.7	1.5	-0.0	-0.1	0.5
Back pain experienced in last month	0.3	0.4	3.8	0.3	0.0	1.1	-0.1	-0.2	0.1	0.9	1.9	-0.2	-0.1	-0.5	-0.1	0.2	0.7	0.0	0.0	-0.3
Mineral and other dietary supplements	0.5	0.7	3.8	0.7	-0.8	-1.9	-0.5	-0.7	-0.7	-0.5	-0.8	-0.8	-0.6	-0.2	-0.8	-0.5	-1.4	0.1	-0.2	-0.7
Breast cancer (self-reported)	0.6	0.7	3.1	-0.5	0.7	-0.9	0.8	0.6	0.8	0.7	1.8	0.8	0.8	0.9	0.5	0.8	0.3	0.7	0.8	1.0
Asthma (self-reported)	0.1	0.2	1.1	-0.2	0.5	-0.4	0.3	0.5	0.4	0.5	1.1	0.4	0.3	0.6	0.4	0.2	0.6	0.1	0.0	0.5
Osteoporosis (self-reported)	0.7	0.9	2.6	0.9	-1.0	-1.1	-0.9	-0.9	-0.9	-1.6	-0.8	-1.2	-0.9	-0.8	-0.8	-0.8	-0.7	-0.5	-0.9	-0.9
Osteoarthritis (self-reported)	2.6	3.3	5.0	2.2	-2.0	-1.0	-1.9	-2.0	-2.0	-1.5	-1.4	-1.8	-1.9	-1.8	-1.9	-1.8	-1.7	-1.6	-1.9	-2.2
Medication: Aspirin	1.7	2.2	4.5	-1.2	1.4	0.6	1.5	1.4	1.6	2.1	1.3	1.3	1.5	1.2	1.5	1.9	1.7	1.7	1.6	1.3
Medication: Gliclazide	0.3	0.3	1.1	-0.8	-0.1	0.9	-0.0	0.4	-0.0	0.6	0.0	0.6	1.0	-0.1	0.6	0.6	0.8	0.4	0.5	0.5
Illnesses of father: None of the above (group 1)	0.5	0.7	2.9	-0.6	0.8	0.2	0.9	0.6	0.7	0.9	-0.8	0.6	0.7	0.7	0.5	1.7	0.5	0.9	0.8	1.0
Smoking status: Current	0.1	0.1	1.0	-0.3	0.2	1.0	0.1	0.1	0.0	-0.2	0.4	-0.2	0.0	-0.3	0.2	-0.1	0.3	-0.3	-0.1	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	1.9	0.4	-0.1	-1.4	0.0	-0.2	-0.3	-0.4	0.7	-0.3	-0.4	0.2	-0.3	-0.1	-0.8	-0.2	-0.7	-0.3
Whole body water mass	0.5	3.1	4.7	1.6	-1.9	-1.0	-1.7	-1.9	-2.0	-2.2	-1.5	-2.1	-1.6	-1.6	-1.8	-1.4	-2.0	-1.5	-2.0	-1.7
Leg predicted mass (right)	0.5	2.5	4.5	1.4	-1.8	-1.2	-1.5	-1.6	-1.9	-2.1	-1.4	-1.9	-1.5	-1.4	-1.6	-1.3	-1.8	-1.1	-1.8	-1.5
Arm fat mass (left)	0.3	1.1	3.4	-1.5	0.9	-0.1	1.0	1.2	0.5	0.4	1.8	0.5	1.3	1.1	1.3	1.1	0.8	1.1	0.7	1.2
Number of self-reported non-cancer illnesses	0.1	0.1	0.3	-0.0	0.4	0.6	0.4	0.2	0.4	0.4	0.4	0.2	0.1	0.1	0.3	0.4	0.5	0.4	0.3	0.2
Average weekly champagne plus white wine intake	0.1	0.1	0.3	0.2	-0.4	-0.4	-0.1	-0.3	-0.2	0.2	0.5	-0.1	-0.5	-0.2	-0.4	0.3	-0.3	0.4	-0.2	-0.2
Miserableness	3.4	5.9	9.3	2.8	-2.4	-1.0	-2.4	-2.8	-2.4	-2.6	-0.3	-2.6	-2.8	-2.3	-3.1	-2.7	-2.5	-2.2	-2.4	-2.6
Guilty feelings	1.9	2.9	6.0	1.6	-1.7	-0.7	-1.5	-1.7	-1.8	-2.4	-2.4	-1.9	-1.5	-1.3	-1.8	-1.6	-1.5	-1.2	-2.0	-1.4
Wears glasses or contact lenses	0.3	0.4	1.1	0.4	-0.7	-0.2	-0.6	-0.4	-0.7	-0.8	-1.1	-0.7	-0.8	-0.6	-0.3	-0.5	0.1	-0.3	-0.4	-0.7
Ever taken oral contraceptive pill	0.3	0.4	2.5	0.2	0.1	1.5	0.2	-0.1	0.3	1.6	0.5	0.3	-0.0	-0.4	-0.2	0.5	0.6	-0.2	-0.3	-0.0
Hearing aid user	0.2	0.2	2.6	0.1	-0.2	-1.6	-0.0	0.0	-0.0	-0.6	-0.8	-0.1	0.0	0.3	0.1	0.3	-0.2	0.4	-0.2	0.4
Mother’s age at death	0.1	0.1	0.9	0.3	0.1	-0.0	0.0	-0.0	0.1	-0.9	-0.0	0.0	-0.2	0.1	-0.1	-0.5	0.3	-0.2	-0.1	0.1
Financial situation satisfaction	0.2	0.2	1.7	-0.5	0.1	0.2	0.0	0.3	0.1	-0.1	1.3	0.5	0.5	0.2	0.6	0.5	0.3	0.3	0.3	0.3
Tinnitus: Yes, now most or all of the time	1.7	1.9	4.7	-1.5	1.4	0.2	1.0	1.5	1.6	2.2	2.1	1.4	1.4	1.3	1.5	0.9	0.1	0.8	1.5	1.3
Commuting to job workplace: Public transport	0.5	0.6	2.0	-0.6	0.8	0.1	0.7	0.6	1.0	1.3	1.4	0.8	0.7	0.9	0.5	0.4	-0.5	0.0	0.1	0.6
Eye problems/disorders: Glaucoma	0.3	0.3	1.2	-0.5	0.6	0.2	0.6	0.5	0.5	0.7	0.3	0.5	0.3	0.4	0.5	0.5	0.8	0.8	1.1	0.5
Medication: Blood pressure	0.4	0.7	1.5	-0.7	0.5	1.0	0.6	0.7	0.5	1.2	0.7	1.1	0.5	0.3	1.0	1.2	0.9	0.8	0.9	0.7
Pain type(s) experienced in last month: Hip pain	0.2	0.2	1.0	-0.4	0.5	1.0	0.4	0.4	0.2	0.3	-0.1	-0.2	0.4	0.1	0.6	0.8	1.0	-0.1	-0.0	0.4
Supplements: Fish oil (including cod liver oil)	2.8	3.7	6.6	-1.9	2.0	1.8	1.9	1.9	1.9	2.1	1.8	2.1	1.9	1.6	1.9	2.0	2.6	1.4	1.5	2.1
High cholesterol (Self-reported)	0.1	0.2	1.3	-0.1	0.2	0.7	0.2	0.1	0.1	1.1	-0.7	0.1	0.2	-0.1	0.2	0.6	0.1	0.2	0.3	0.2
Medication: Bendroflumethiazide	0.1	0.1	1.4	-0.2	0.1	1.2	0.0	0.1	-0.0	0.3	0.1	0.1	0.2	-0.3	0.2	-0.0	0.5	-0.2	-0.2	-0.0
Medication: Paracetamol	0.5	0.7	1.7	1.3	-0.9	-0.1	-0.7	-1.1	-1.1	-0.2	-0.1	-1.3	-0.9	-1.0	-1.0	-0.7	-0.1	-0.5	-0.7	-0.9
Medication: Lisinopril	0.3	0.4	1.2	-1.0	0.2	-0.1	-0.1	0.6	0.1	0.8	0.1	0.9	0.8	0.5	1.1	-0.0	0.6	0.1	0.9	0.4
Medication: Atorvastatin	1.6	1.9	3.9	1.1	-1.7	-0.0	-1.8	-1.4	-1.6	-1.2	-1.1	-1.2	-0.9	-1.5	-1.1	-2.0	-1.4	-1.7	-1.4	-1.4
Illnesses of father: High blood pressure	0.6	0.8	2.0	0.5	-1.0	0.2	-1.1	-0.7	-0.9	-1.4	0.3	-0.8	-0.5	-0.8	-0.6	-1.3	-0.6	-1.2	-1.1	-0.9
Alcohol drinker status: Never	1.8	2.1	4.0	-1.2	1.6	-1.2	1.8	1.5	1.6	1.2	0.9	1.5	1.0	1.9	1.1	1.5	1.0	2.0	1.5	1.6
Ever smoked	0.5	0.9	1.6	0.7	-1.0	0.6	-1.1	-1.0	-0.9	-1.2	-0.6	-1.3	-1.0	-1.2	-0.8	-0.9	-0.6	-1.0	-0.6	-0.8
Basal metabolic rate	0.4	2.2	3.6	1.2	-1.6	-0.9	-1.4	-1.5	-1.8	-1.9	-1.1	-1.9	-1.3	-1.4	-1.5	-1.1	-1.7	-1.2	-1.7	-1.4
Leg fat percentage (left)	2.0	7.2	11.9	-3.2	2.6	0.9	2.7	3.0	2.3	1.8	3.4	2.4	3.0	2.6	3.1	2.7	2.5	2.7	2.6	2.9
Arm fat-free mass (left)	0.1	0.6	1.4	0.6	-0.8	-0.6	-0.6	-0.8	-0.9	-1.0	-0.7	-1.1	-0.6	-0.7	-0.9	-0.3	-1.2	-0.5	-1.0	-0.7
Number of operations (self-reported)	0.3	0.4	3.4	-0.7	0.0	-0.2	-0.1	0.2	-0.3	-0.9	-1.9	0.3	0.1	0.2	0.5	0.3	-0.4	0.1	0.9	0.3
Average weekly beer plus cider intake	0.5	0.8	1.5	0.6	-1.0	-0.6	-0.9	-0.8	-0.9	-1.2	-0.1	-1.0	-0.5	-0.8	-0.8	-1.1	-1.2	-0.8	-1.1	-0.6
Irritability	0.4	0.7	3.8	0.5	-0.7	-0.5	-0.4	-0.6	-1.1	-2.0	-1.5	-0.7	-0.9	-0.6	-0.5	-0.1	0.0	0.2	-0.7	-0.6
Risk taking	0.9	1.3	3.2	-0.9	1.7	0.7	1.6	1.3	1.8	1.1	0.1	0.9	1.1	1.3	0.9	0.9	0.6	1.0	1.0	1.3
Ever had prostate specific antigen (PSA) test	4.1	4.8	8.1	2.2	-2.3	-0.9	-2.3	-2.2	-2.3	-2.8	-0.8	-2.5	-2.3	-2.2	-2.0	-2.4	-2.3	-2.3	-2.3	-2.3
Fractured/broken bones in last 5 years	0.6	0.8	2.2	-1.1	1.0	0.6	0.7	0.9	0.9	1.5	0.2	0.8	1.0	0.7	1.0	0.4	0.8	0.4	1.1	0.8
Age started oral contraceptive pill	10.6	13.2	16.0	-4.0	3.9	1.8	3.9	4.0	3.9	3.1	3.3	3.8	4.0	3.5	3.9	3.7	3.9	3.3	3.4	4.0
Diastolic blood pressure, automated reading	0.2	0.5	5.3	-0.4	0.1	1.5	-0.3	-0.1	0.3	-0.1	2.3	0.6	0.0	-0.1	0.1	-0.2	-0.3	-0.9	-0.2	0.3
Ever depressed for a whole week	0.5	0.7	3.2	1.0	-0.6	-0.9	-0.5	-0.9	-0.3	-0.4	0.2	-1.0	-0.9	-0.4	-1.1	-0.3	-1.8	-0.2	-0.9	-0.8
Unable to work because of sickness or disability	0.8	1.1	2.3	-1.1	0.9	-0.2	1.0	1.1	0.8	1.5	-0.8	0.8	0.9	1.2	1.2	1.2	0.9	1.0	1.3	1.2
Commuting to job workplace: Cycle	0.9	1.0	2.6	-1.1	1.2	1.6	1.1	1.2	1.1	0.2	-0.1	1.1	0.9	0.7	1.3	1.0	1.2	0.5	0.7	1.0
Myopia	1.0	1.4	4.0	-0.8	0.9	-1.6	1.2	0.9	1.1	1.7	0.2	0.8	0.9	1.4	0.8	1.3	0.6	2.0	1.5	0.9
Vascular/heart problems diagnosed by doctor	0.2	0.6	2.8	0.5	-0.3	-0.9	-0.4	-0.5	-0.5	-1.5	-1.7	-1.0	-0.5	-0.2	-0.7	-0.9	-0.8	-0.5	-0.3	-0.4
Cholesterol lowering medication	0.3	0.5	1.8	-0.4	0.3	1.3	0.3	0.3	0.1	1.2	-1.2	0.4	0.5	-0.1	0.5	1.1	0.3	0.3	0.5	0.6
Medication: Omeprazole (e.g. Zanprol)	0.7	0.9	2.3	0.8	-1.5	0.1	-1.5	-1.1	-1.4	-0.8	-0.2	-0.8	-0.8	-1.3	-0.6	-0.6	-0.2	-1.0	-0.9	-0.8
Pain experienced in last month	0.9	1.5	2.8	-1.4	1.2	-0.9	1.3	1.5	1.4	0.7	-0.5	1.7	1.3	1.6	1.3	1.0	0.1	1.2	1.1	1.4
Supplements: Calcium	0.3	0.3	1.0	-0.6	0.4	1.0	-0.0	0.5	0.2	0.1	-0.6	0.2	0.9	0.2	0.8	-0.2	0.7	-0.5	-0.2	0.4
Basal cell carcinoma (self-reported)	0.7	0.9	3.7	-0.8	1.0	1.9	0.8	0.8	1.0	1.3	-0.5	1.0	0.7	0.3	0.8	0.7	1.3	0.5	0.7	0.6
Heart attack/myocardial infarction (self-reported)	1.8	2.3	5.2	-1.3	1.1	-0.3	1.6	1.3	1.2	2.2	2.3	1.2	1.7	1.3	1.3	1.9	1.2	1.8	1.2	1.5
Deep venous thrombosis (DVT) (self-reported)	3.6	4.6	7.0	-2.6	1.9	1.0	2.0	2.2	2.0	2.3	0.7	2.1	2.5	1.9	2.4	2.4	2.3	2.3	2.6	2.2
Heart disease (siblings)	0.4	0.5	3.2	0.3	0.3	-1.4	0.6	0.1	0.7	0.3	1.8	0.0	-0.1	0.5	-0.1	0.1	-0.2	1.1	0.9	0.1
Alcohol drinker status: Previous	2.4	2.8	7.6	1.7	-1.6	0.5	-1.6	-1.7	-1.6	-2.8	0.1	-1.8	-1.8	-2.0	-1.6	-1.7	-0.6	-1.6	-1.7	-1.9
Pack years of smoking	0.7	1.0	4.3	-0.7	0.7	-2.1	0.7	0.9	0.4	1.1	-0.9	0.4	0.7	1.4	0.9	0.8	-0.6	1.2	1.4	1.0
Impedance of whole body	0.3	1.7	3.2	1.3	-1.4	0.6	-1.6	-1.4	-1.2	-1.2	0.3	-1.0	-1.3	-1.6	-1.3	-1.8	-0.7	-1.7	-1.0	-1.4
Leg fat mass (left)	0.8	3.0	5.5	-2.3	1.6	0.4	1.7	1.9	1.2	0.8	2.4	1.4	2.1	1.7	2.1	1.9	1.5	1.9	1.7	1.9
Arm predicted mass (left)	0.2	0.8	1.6	0.7	-1.0	-0.2	-0.8	-0.9	-1.1	-1.3	-0.6	-1.2	-0.7	-1.0	-0.9	-0.4	-1.2	-0.8	-1.2	-0.8