[Hub]/) : Traits : Standing height :

chr14:91,531,030-93,268,359

Best TWAS P=1.4e-34 · Best GWAS P=1.66e-36 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ATXN3 0.10 0.06 enet 10 0.11 5.4e-13 -8.68 5.3 1.2e-07 -0.34 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous ATXN3 0.19 0.17 lasso 5 0.17 1.7e-13 -10.33 -10.5 1.2e-25 0.72 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous RP11-529H20.5 0.14 0.16 lasso 3 0.15 3.0e-12 -10.33 -11.5 8.0e-31 0.83 0.68 0.32 FALSE
4 GTEx Adipose Subcutaneous RP11-529H20.6 0.16 0.26 lasso 2 0.26 4.8e-21 -10.46 -10.4 1.5e-25 0.72 1.00 0.00 FALSE
5 GTEx Adipose Visceral Omentum ATXN3 0.19 0.14 lasso 6 0.12 7.0e-07 -10.41 -10.5 1.2e-25 0.72 0.62 0.37 FALSE
6 GTEx Adipose Visceral Omentum RP11-529H20.5 0.19 0.05 lasso 6 0.08 9.9e-05 -10.38 -10.6 3.3e-26 0.80 0.46 0.54 FALSE
7 GTEx Adipose Visceral Omentum RP11-529H20.6 0.26 0.29 lasso 4 0.28 1.1e-14 -10.53 -10.4 1.8e-25 0.73 1.00 0.00 FALSE
8 GTEx Adrenal Gland RP11-529H20.6 0.22 0.21 lasso 7 0.18 4.8e-07 -10.51 -10.0 2.2e-23 0.71 0.84 0.09 FALSE
9 GTEx Artery Aorta TRIP11 0.20 0.00 enet 8 0.02 4.0e-02 -10.33 -8.4 5.8e-17 0.75 0.15 0.24 FALSE
10 GTEx Artery Aorta RP11-529H20.6 0.20 0.14 lasso 4 0.18 6.4e-10 -10.46 -10.6 3.1e-26 0.71 0.97 0.01 FALSE
11 GTEx Artery Coronary ATXN3 0.21 0.20 lasso 2 0.24 1.4e-08 -10.46 -9.8 8.7e-23 0.64 0.64 0.29 FALSE
12 GTEx Artery Coronary TRIP11 0.18 0.01 lasso 3 0.00 3.2e-01 -10.06 -9.1 9.1e-20 0.74 0.09 0.24 FALSE
13 GTEx Artery Coronary RP11-529H20.6 0.44 -0.01 enet 49 0.08 1.1e-03 0.26 -5.3 1.4e-07 0.38 0.49 0.10 FALSE
14 GTEx Artery Tibial ATXN3 0.13 0.11 lasso 3 0.10 5.8e-08 -11.05 -11.0 2.9e-28 0.85 0.89 0.11 FALSE
15 GTEx Artery Tibial RP11-529H20.5 0.07 0.00 lasso 4 0.00 4.7e-01 -12.36 -12.3 1.4e-34 0.95 0.03 0.87 TRUE
16 GTEx Artery Tibial RP11-529H20.6 0.20 0.22 lasso 8 0.22 2.3e-17 -10.46 -10.5 1.5e-25 0.72 1.00 0.00 FALSE
17 GTEx Brain Frontal Cortex BA9 RP11-747H7.3 0.20 0.15 lasso 2 0.09 2.1e-03 6.16 5.4 5.5e-08 0.12 0.14 0.20 FALSE
18 GTEx Brain Hippocampus ATXN3 0.28 0.03 lasso 16 0.12 8.9e-04 -4.95 -7.0 2.4e-12 0.61 0.14 0.29 FALSE
19 GTEx Brain Hypothalamus RP11-747H7.3 0.34 0.12 lasso 6 0.18 6.0e-05 6.16 5.3 1.3e-07 0.04 0.20 0.04 FALSE
20 GTEx Brain Putamen basal ganglia RP11-529H20.6 0.44 0.14 enet 45 0.26 6.1e-07 -12.52 -9.5 3.0e-21 0.85 0.01 0.98 FALSE
21 GTEx Breast Mammary Tissue ATXN3 0.20 0.24 lasso 8 0.23 3.5e-12 -10.46 -10.6 2.9e-26 0.74 0.95 0.05 FALSE
22 GTEx Breast Mammary Tissue RP11-529H20.5 0.22 0.10 enet 23 0.12 1.1e-06 -10.41 -9.4 7.0e-21 0.75 0.23 0.77 FALSE
23 GTEx Breast Mammary Tissue RP11-529H20.6 0.20 0.23 enet 13 0.27 3.5e-14 -10.46 -10.3 6.0e-25 0.75 0.96 0.04 FALSE
24 GTEx Breast Mammary Tissue (Female) ATXN3 0.18 0.04 lasso 4 0.03 3.3e-02 -11.05 -11.1 7.8e-29 0.84 0.15 0.70 FALSE
25 GTEx Breast Mammary Tissue (Female) TC2N 0.04 -0.01 lasso 5 0.06 7.0e-03 6.19 5.7 1.6e-08 0.10 0.05 0.08 FALSE
26 GTEx Breast Mammary Tissue (Female) RP11-529H20.5 0.17 -0.01 enet 35 -0.01 5.8e-01 -10.41 -8.5 1.4e-17 0.66 0.05 0.56 FALSE
27 GTEx Breast Mammary Tissue (Female) RP11-747H7.3 0.10 0.06 lasso 6 0.07 4.9e-03 6.19 6.1 9.6e-10 0.08 0.12 0.05 FALSE
28 GTEx Breast Mammary Tissue (Female) RP11-529H20.6 0.22 0.13 lasso 3 0.09 1.5e-03 -10.41 -9.7 2.5e-22 0.71 0.14 0.83 FALSE
29 GTEx Cells EBV-transformed lymphocytes RP11-529H20.6 0.41 0.30 lasso 2 0.28 6.9e-10 -10.46 -10.3 7.0e-25 0.70 0.97 0.02 FALSE
30 GTEx Cells Transformed fibroblasts ATXN3 0.14 0.10 lasso 9 0.09 6.0e-07 -10.33 -10.5 1.4e-25 0.72 1.00 0.00 FALSE
31 GTEx Cells Transformed fibroblasts TRIP11 0.09 0.04 lasso 2 0.00 3.8e-01 -10.51 -10.6 5.0e-26 0.70 0.24 0.03 FALSE
32 GTEx Cells Transformed fibroblasts RP11-529H20.5 0.10 0.13 lasso 11 0.12 3.1e-09 -10.36 -10.3 4.2e-25 0.72 1.00 0.00 FALSE
33 GTEx Cells Transformed fibroblasts RP11-529H20.6 0.27 0.26 lasso 6 0.24 3.1e-18 -10.46 -10.6 1.7e-26 0.74 1.00 0.00 FALSE
34 GTEx Colon Sigmoid ATXN3 0.31 0.30 lasso 2 0.33 3.4e-12 -10.46 -9.2 5.0e-20 0.68 1.00 0.00 FALSE
35 GTEx Colon Sigmoid TRIP11 0.15 0.09 enet 18 0.07 1.7e-03 -3.49 -7.1 1.3e-12 0.53 0.15 0.33 FALSE
36 GTEx Colon Sigmoid TC2N 0.18 0.03 enet 14 0.02 6.6e-02 -11.87 -5.2 1.8e-07 0.58 0.06 0.70 FALSE
37 GTEx Colon Sigmoid RP11-529H20.5 0.27 0.05 lasso 8 0.04 1.9e-02 -10.05 -8.5 1.7e-17 0.76 0.42 0.14 FALSE
38 GTEx Colon Sigmoid RP11-529H20.6 0.24 0.24 lasso 3 0.27 4.8e-10 -10.46 -10.0 1.1e-23 0.71 1.00 0.00 FALSE
39 GTEx Colon Transverse RP11-529H20.6 0.18 0.14 lasso 5 0.18 3.7e-09 -10.46 -8.9 5.5e-19 0.68 1.00 0.00 FALSE
40 GTEx Esophagus Gastroesophageal Junction ATXN3 0.32 0.17 enet 41 0.18 6.1e-07 -10.33 -7.2 6.0e-13 0.65 0.93 0.04 FALSE
41 GTEx Esophagus Gastroesophageal Junction TRIP11 0.16 0.13 lasso 11 0.12 3.7e-05 -11.01 -9.9 4.2e-23 0.78 0.54 0.16 FALSE
42 GTEx Esophagus Gastroesophageal Junction RP11-529H20.5 0.17 0.02 enet 23 0.01 9.6e-02 -10.39 -7.9 3.9e-15 0.59 0.28 0.23 FALSE
43 GTEx Esophagus Gastroesophageal Junction RP11-529H20.6 0.26 0.27 enet 26 0.26 6.2e-10 -10.33 -9.5 1.3e-21 0.73 0.99 0.01 FALSE
44 GTEx Esophagus Mucosa TRIP11 0.09 0.01 lasso 4 0.00 2.4e-01 -10.05 -9.2 4.0e-20 0.74 0.12 0.28 FALSE
45 GTEx Esophagus Mucosa RP11-529H20.6 0.13 0.11 lasso 10 0.13 7.9e-09 -10.38 -11.7 1.9e-31 0.87 0.08 0.92 FALSE
46 GTEx Esophagus Muscularis ATXN3 0.16 0.17 lasso 5 0.17 2.0e-10 -10.33 -10.9 1.5e-27 0.79 0.99 0.01 FALSE
47 GTEx Esophagus Muscularis TRIP11 0.10 0.11 lasso 4 0.10 8.3e-07 -10.33 -9.7 2.0e-22 0.71 0.56 0.44 FALSE
48 GTEx Esophagus Muscularis RP11-529H20.5 0.17 0.11 enet 19 0.11 2.9e-07 -10.33 -9.9 2.7e-23 0.75 0.76 0.24 FALSE
49 GTEx Esophagus Muscularis RP11-529H20.6 0.21 0.24 lasso 2 0.22 9.2e-14 -10.33 -10.3 5.3e-25 0.72 1.00 0.00 FALSE
50 GTEx Heart Atrial Appendage RP11-529H20.6 0.27 0.20 lasso 5 0.18 2.5e-08 -10.46 -10.4 3.7e-25 0.71 0.98 0.01 FALSE
51 GTEx Heart Left Ventricle TC2N 0.13 0.10 enet 15 0.10 6.5e-06 6.19 6.1 9.6e-10 0.13 0.88 0.02 FALSE
52 GTEx Heart Left Ventricle RP11-529H20.5 0.10 0.03 enet 8 0.06 2.7e-04 -11.58 -10.0 1.0e-23 0.77 0.03 0.90 FALSE
53 GTEx Heart Left Ventricle RP11-529H20.6 0.13 0.12 enet 14 0.12 3.4e-07 -10.46 -9.9 2.6e-23 0.76 0.80 0.18 FALSE
54 GTEx Lung RP11-529H20.6 0.08 0.05 enet 15 0.05 1.8e-04 -10.46 -11.6 4.6e-31 0.83 0.58 0.38 FALSE
55 GTEx Muscle Skeletal ATXN3 0.04 0.04 lasso 5 0.04 1.2e-04 -10.33 -10.7 1.5e-26 0.76 0.33 0.58 FALSE
56 GTEx Muscle Skeletal TRIP11 0.05 0.04 lasso 6 0.03 7.9e-04 -10.39 -9.9 6.3e-23 0.72 0.38 0.43 FALSE
57 GTEx Muscle Skeletal RP11-529H20.6 0.11 0.06 lasso 2 0.06 2.9e-06 -10.46 -10.5 5.8e-26 0.72 0.98 0.02 FALSE
58 GTEx Nerve Tibial ATXN3 0.30 0.29 lasso 4 0.29 1.6e-20 -10.33 -10.1 7.1e-24 0.72 1.00 0.00 FALSE
59 GTEx Nerve Tibial TRIP11 0.21 0.14 lasso 6 0.11 3.7e-08 -10.33 -10.3 8.2e-25 0.73 1.00 0.00 FALSE
60 GTEx Nerve Tibial RP11-529H20.5 0.28 0.26 lasso 5 0.25 9.2e-18 -10.33 -10.4 3.8e-25 0.73 1.00 0.00 FALSE
61 GTEx Nerve Tibial RP11-529H20.6 0.29 0.30 lasso 4 0.29 4.4e-21 -10.33 -10.4 3.3e-25 0.72 1.00 0.00 FALSE
62 GTEx Ovary ATXN3 0.32 0.18 lasso 8 0.18 2.9e-05 -10.33 -10.1 5.5e-24 0.72 0.16 0.69 FALSE
63 GTEx Ovary RP11-529H20.5 0.24 0.10 lasso 5 0.11 1.2e-03 -10.33 -10.1 8.3e-24 0.74 0.05 0.81 FALSE
64 GTEx Ovary RP11-529H20.6 0.20 0.23 lasso 4 0.18 4.3e-05 -10.46 -10.9 6.8e-28 0.76 0.06 0.86 FALSE
65 GTEx Pituitary ATXN3 0.33 0.03 lasso 2 0.03 4.7e-02 -10.46 -10.8 3.6e-27 0.75 0.26 0.10 FALSE
66 GTEx Pituitary RP11-529H20.5 0.37 0.14 enet 7 0.07 6.3e-03 -11.58 -11.0 5.5e-28 0.79 0.20 0.23 FALSE
67 GTEx Prostate ATXN3 0.30 0.04 lasso 5 0.06 1.4e-02 -10.46 -7.8 7.4e-15 0.56 0.09 0.09 FALSE
68 GTEx Prostate TRIP11 0.42 -0.01 enet 79 0.05 1.8e-02 -12.52 -6.0 2.4e-09 0.31 0.03 0.70 FALSE
69 GTEx Prostate RP11-529H20.6 0.28 0.00 lasso 5 0.05 2.5e-02 -10.46 -11.1 7.8e-29 0.59 0.15 0.08 FALSE
70 GTEx Skin Sun Exposed Lower leg ATXN3 0.07 0.02 enet 15 0.02 5.8e-03 4.69 -6.8 1.1e-11 0.68 0.05 0.75 FALSE
71 GTEx Skin Sun Exposed Lower leg TC2N 0.09 0.06 lasso 5 0.06 4.6e-06 6.16 5.9 4.2e-09 0.10 0.98 0.00 FALSE
72 GTEx Small Intestine Terminal Ileum RP11-747H7.3 0.31 0.14 lasso 2 0.04 3.8e-02 6.16 6.2 7.4e-10 0.09 0.07 0.05 FALSE
73 GTEx Small Intestine Terminal Ileum RP11-529H20.6 0.36 0.32 lasso 8 0.26 1.8e-06 -10.53 -10.1 3.9e-24 0.70 0.53 0.36 FALSE
74 GTEx Spleen ATXN3 0.27 0.03 lasso 3 0.01 1.5e-01 -10.33 -9.3 9.9e-21 0.69 0.06 0.65 FALSE
75 GTEx Spleen RP11-529H20.5 0.31 0.15 lasso 3 0.18 2.3e-05 -11.58 -11.6 3.0e-31 0.80 0.08 0.50 FALSE
76 GTEx Spleen RP11-529H20.6 0.53 0.22 enet 40 0.32 6.2e-09 -10.33 -8.5 1.7e-17 0.68 0.29 0.70 FALSE
77 GTEx Stomach ATXN3 0.24 0.09 lasso 3 0.11 5.0e-06 -10.46 -10.9 9.4e-28 0.78 0.87 0.11 FALSE
78 GTEx Stomach RP11-529H20.5 0.19 0.12 enet 32 0.12 2.2e-06 -10.46 -9.2 2.8e-20 0.73 0.19 0.80 FALSE
79 GTEx Stomach RP11-529H20.6 0.20 0.27 lasso 4 0.25 2.5e-12 -10.33 -10.4 2.5e-25 0.72 1.00 0.00 FALSE
80 GTEx Testis TRIP11 0.10 0.05 lasso 4 0.02 3.5e-02 -10.51 -10.3 5.4e-25 0.72 0.09 0.74 FALSE
81 GTEx Testis RP11-529H20.5 0.19 0.05 lasso 10 0.05 4.2e-03 -10.33 -11.8 3.5e-32 0.83 0.04 0.94 FALSE
82 GTEx Testis RP11-529H20.6 0.23 0.23 lasso 3 0.22 4.9e-10 -10.46 -10.5 5.5e-26 0.71 0.94 0.06 FALSE
83 GTEx Thyroid ATXN3 0.13 0.05 enet 11 0.14 5.5e-11 -10.46 -8.8 1.1e-18 0.66 0.11 0.88 FALSE
84 GTEx Thyroid TRIP11 0.08 0.04 lasso 4 0.02 6.3e-03 -10.43 -9.3 9.9e-21 0.69 0.42 0.23 FALSE
85 GTEx Thyroid RP11-529H20.5 0.14 0.12 enet 14 0.13 7.7e-10 -11.58 -9.0 1.6e-19 0.67 0.26 0.74 FALSE
86 GTEx Thyroid RP11-529H20.6 0.17 0.18 lasso 2 0.17 9.6e-13 -10.46 -10.6 4.0e-26 0.73 1.00 0.00 FALSE
87 GTEx Whole Blood RP11-529H20.5 0.13 0.09 lasso 5 0.08 1.2e-07 -11.58 -11.5 1.2e-30 0.82 0.39 0.60 FALSE
88 GTEx Whole Blood RP11-529H20.6 0.15 0.13 lasso 4 0.16 3.8e-14 -10.46 -11.5 1.3e-30 0.80 0.50 0.50 FALSE
89 METSIM Adipose ATXN3 0.08 0.02 bslmm 541 0.04 3.1e-06 -10.51 -8.0 1.0e-15 0.54 0.88 0.10 FALSE
90 METSIM Adipose TC2N 0.08 0.05 enet 23 0.05 3.4e-08 -6.56 6.1 8.7e-10 0.26 0.96 0.04 TRUE
91 METSIM Adipose TRIP11 0.05 0.04 enet 13 0.02 3.8e-04 -12.52 -11.9 1.8e-32 0.89 0.00 1.00 FALSE
92 YFS Blood ATXN3 0.20 0.14 enet 52 0.24 1.1e-75 -10.35 -9.4 7.9e-21 0.78 1.00 0.00 FALSE
93 YFS Blood TC2N 0.44 0.34 lasso 12 0.38 2.0e-132 -3.60 5.4 6.5e-08 0.00 1.00 0.00 TRUE
94 YFS Blood TRIP11 0.06 0.04 blup 510 0.04 4.4e-14 -11.05 -9.7 3.1e-22 0.74 0.59 0.41 FALSE
95 The Cancer Genome Atlas Breast Invasive Carcinoma FBLN5 0.05 0.01 lasso 3 0.02 1.2e-04 4.23 7.0 3.1e-12 -0.22 0.34 0.02 FALSE
96 The Cancer Genome Atlas Colon Adenocarcinoma TRIP11 0.04 0.01 blup 70 0.01 4.4e-02 9.37 -11.5 1.1e-30 0.82 0.04 0.48 FALSE
97 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TRIP11 0.02 0.02 lasso 1 0.01 1.1e-02 -10.41 -10.4 2.2e-25 0.72 0.14 0.12 FALSE
98 The Cancer Genome Atlas Brain Lower Grade Glioma TRIP11 0.04 0.01 blup 71 0.02 1.4e-03 -3.85 -6.3 2.2e-10 0.40 0.09 0.04 FALSE
99 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TC2N 0.17 0.12 blup 83 0.12 2.1e-05 -6.56 7.9 4.0e-15 0.06 0.36 0.22 FALSE
100 The Cancer Genome Atlas Skin Cutaneous Melanoma TC2N 0.20 0.04 enet 18 0.04 2.4e-02 3.53 5.7 1.5e-08 0.16 0.02 0.11 FALSE
101 The Cancer Genome Atlas Testicular Germ Cell Tumors TRIP11 0.16 0.16 lasso 12 0.15 4.4e-06 -11.05 -9.6 6.2e-22 0.71 0.30 0.59 FALSE
102 The Cancer Genome Atlas Thyroid Carcinoma CATSPERB 0.10 0.01 lasso 6 0.03 6.8e-04 -2.83 5.2 1.9e-07 0.13 0.00 0.04 FALSE
103 The Cancer Genome Atlas Thyroid Carcinoma TC2N 0.07 0.06 enet 10 0.06 2.8e-06 -6.56 7.0 3.6e-12 0.03 0.74 0.25 FALSE
104 The Cancer Genome Atlas Thyroid Carcinoma TRIP11 0.08 0.04 blup 70 0.06 3.6e-06 -8.17 -8.7 3.1e-18 0.74 0.35 0.62 FALSE
105 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma TRIP11 0.14 0.04 blup 70 0.09 1.6e-03 -8.93 -11.6 2.7e-31 0.90 0.03 0.62 FALSE