[Hub]/) : Traits : Standing height :

chr14:74,176,318-77,117,550

Best TWAS P=1.06e-18 · Best GWAS P=1.19e-35 conditioned to 1.27e-13

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLST 0.09 0.11 lasso 2 0.11 4.0e-13 5.7 -5.7 9.9e-09 0.00 1.00 0.00 FALSE
2 CommonMind Brain Pre-frontal Cortex SYNDIG1L 0.19 0.09 enet 17 0.12 4.5e-14 -4.7 -6.1 9.3e-10 0.67 0.99 0.01 FALSE
3 CommonMind Brain Pre-frontal Cortex TTLL5 0.13 0.15 lasso 10 0.19 1.2e-22 6.0 -7.3 3.9e-13 0.01 0.88 0.12 FALSE
4 GTEx Adipose Subcutaneous TTLL5 0.13 0.10 lasso 4 0.11 2.2e-09 5.6 -6.2 4.7e-10 0.00 0.97 0.03 FALSE
5 GTEx Artery Aorta TTLL5 0.09 0.11 lasso 3 0.07 1.1e-04 6.3 -6.3 3.4e-10 0.03 0.65 0.17 FALSE
6 GTEx Artery Tibial NPC2 0.17 0.14 lasso 2 0.14 4.1e-11 6.4 6.0 2.1e-09 -0.43 1.00 0.00 FALSE
7 GTEx Artery Tibial TTLL5 0.09 0.05 lasso 4 0.05 1.3e-04 5.3 -5.9 4.8e-09 -0.01 0.80 0.08 FALSE
8 GTEx Brain Cerebellar Hemisphere TTLL5 0.19 0.06 lasso 2 0.02 9.7e-02 6.2 -6.4 1.5e-10 0.05 0.11 0.31 FALSE
9 GTEx Brain Cortex TTLL5 0.23 0.09 lasso 13 0.07 5.9e-03 7.4 -7.8 5.7e-15 0.02 0.07 0.70 FALSE
10 GTEx Brain Frontal Cortex BA9 TTLL5 0.24 0.00 enet 18 0.00 3.0e-01 6.6 -5.3 1.2e-07 0.02 0.09 0.49 FALSE
11 GTEx Cells EBV-transformed lymphocytes TTLL5 0.24 0.01 enet 27 0.15 1.1e-05 6.0 -5.9 4.9e-09 0.00 0.10 0.62 FALSE
12 GTEx Cells Transformed fibroblasts TTLL5 0.09 0.09 lasso 6 0.11 1.6e-08 6.4 -6.6 4.8e-11 0.01 0.77 0.22 FALSE
13 GTEx Cells Transformed fibroblasts FLVCR2 0.21 0.16 lasso 8 0.17 1.2e-12 7.0 7.1 1.1e-12 0.00 0.18 0.82 FALSE
14 GTEx Cells Transformed fibroblasts AC007182.6 0.18 0.20 lasso 7 0.18 2.1e-13 7.0 7.2 4.7e-13 -0.01 0.24 0.76 FALSE
15 GTEx Esophagus Gastroesophageal Junction TTLL5 0.16 0.03 lasso 3 0.01 1.2e-01 5.3 -5.5 4.8e-08 -0.01 0.21 0.42 TRUE
16 GTEx Esophagus Mucosa TTLL5 0.11 0.00 lasso 5 0.00 2.4e-01 5.7 -6.0 2.2e-09 0.00 0.28 0.27 FALSE
17 GTEx Lung TTLL5 0.15 0.08 enet 17 0.11 9.0e-09 5.6 -6.6 5.6e-11 0.00 0.92 0.08 FALSE
18 GTEx Muscle Skeletal TTLL5 0.05 0.04 lasso 2 0.03 1.2e-03 5.4 -5.2 1.5e-07 0.02 0.57 0.21 FALSE
19 GTEx Nerve Tibial NPC2 0.11 0.09 lasso 2 0.07 1.6e-05 6.4 6.0 1.9e-09 -0.48 0.70 0.03 FALSE
20 GTEx Nerve Tibial TTLL5 0.08 0.05 lasso 3 0.04 5.1e-04 6.4 -6.7 1.5e-11 0.01 0.10 0.56 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic RPS6KL1 0.08 0.08 enet 11 0.07 1.5e-04 -5.0 -5.9 3.5e-09 0.02 0.87 0.00 FALSE
22 GTEx Skin Not Sun Exposed Suprapubic RP11-950C14.3 0.07 0.03 enet 8 0.03 1.2e-02 4.3 -5.5 2.9e-08 0.04 0.36 0.04 FALSE
23 GTEx Skin Sun Exposed Lower leg NPC2 0.11 0.11 enet 11 0.10 2.7e-08 6.4 6.0 1.8e-09 -0.56 0.99 0.01 FALSE
24 GTEx Skin Sun Exposed Lower leg TTLL5 0.15 0.05 enet 23 0.07 2.8e-06 5.3 -5.4 8.4e-08 -0.02 0.54 0.43 FALSE
25 GTEx Small Intestine Terminal Ileum RPS6KL1 0.57 0.12 lasso 16 0.10 2.9e-03 -4.3 -6.7 2.3e-11 0.12 0.12 0.06 TRUE
26 GTEx Spleen ACYP1 0.27 0.00 lasso 4 0.01 1.5e-01 4.1 -6.2 5.7e-10 0.03 0.06 0.15 FALSE
27 GTEx Thyroid NPC2 0.13 0.05 lasso 4 0.02 4.9e-03 6.1 6.1 1.1e-09 -0.47 0.12 0.59 FALSE
28 GTEx Thyroid RPS6KL1 0.23 0.14 enet 14 0.14 1.3e-10 -4.7 -5.5 3.5e-08 0.13 1.00 0.00 FALSE
29 GTEx Whole Blood ISCA2 0.15 0.05 enet 18 0.08 5.4e-08 6.1 6.2 7.2e-10 -0.53 0.74 0.13 FALSE
30 METSIM Adipose NPC2 0.03 0.01 lasso 2 0.01 1.4e-02 6.4 6.3 2.3e-10 -0.50 0.19 0.60 FALSE
31 METSIM Adipose TTLL5 0.12 0.01 blup 624 0.05 2.1e-07 5.4 -6.6 3.5e-11 0.02 0.24 0.57 FALSE
32 NTR Blood ISCA2 0.10 0.07 lasso 6 0.07 1.6e-21 6.1 6.0 2.2e-09 -0.49 1.00 0.00 FALSE
33 NTR Blood NPC2 0.02 0.01 lasso 5 0.01 6.3e-03 -7.9 8.6 7.1e-18 -0.73 0.03 0.96 FALSE
34 YFS Blood ISCA2 0.22 0.19 enet 11 0.21 7.1e-66 6.4 6.7 1.7e-11 -0.61 1.00 0.00 FALSE
35 YFS Blood NPC2 0.09 0.06 enet 10 0.07 1.6e-22 -8.1 8.8 1.1e-18 -0.73 1.00 0.00 TRUE
36 YFS Blood TTLL5 0.04 0.04 lasso 6 0.03 1.4e-10 5.7 -6.7 1.7e-11 -0.01 1.00 0.00 FALSE
37 The Cancer Genome Atlas Breast Invasive Carcinoma RPS6KL1 0.03 0.02 lasso 3 0.02 8.5e-06 -5.1 -5.2 1.9e-07 0.03 0.02 0.98 FALSE
38 The Cancer Genome Atlas Breast Invasive Carcinoma TTLL5 0.01 0.02 enet 7 0.02 3.6e-05 5.9 -7.0 2.0e-12 0.01 0.10 0.67 FALSE
39 The Cancer Genome Atlas Colon Adenocarcinoma TTLL5 0.07 0.04 blup 121 0.06 2.4e-04 7.1 -7.1 9.7e-13 0.02 0.10 0.87 FALSE
40 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TTLL5 0.04 0.02 blup 121 0.04 1.1e-05 6.0 -7.0 2.2e-12 0.01 0.38 0.61 FALSE
41 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS6KL1 0.04 0.04 lasso 3 0.03 1.8e-04 -5.1 -5.2 1.8e-07 0.02 0.02 0.96 FALSE
42 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TTLL5 0.04 0.03 blup 121 0.04 2.8e-05 6.0 -6.6 3.5e-11 0.01 0.75 0.18 FALSE
43 The Cancer Genome Atlas Brain Lower Grade Glioma TTLL5 0.06 0.07 blup 121 0.06 1.3e-07 6.0 -5.7 9.4e-09 0.02 0.77 0.22 FALSE
44 The Cancer Genome Atlas Lung Adenocarcinoma TTLL5 0.03 0.01 blup 122 0.02 3.2e-03 6.0 -7.8 4.4e-15 0.01 0.05 0.87 TRUE
45 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TTLL5 0.02 0.01 blup 121 0.02 2.5e-03 6.4 -7.3 3.7e-13 0.00 0.08 0.33 FALSE
46 The Cancer Genome Atlas Prostate Adenocarcinoma TTLL5 0.03 0.03 lasso 3 0.02 1.6e-03 5.7 -6.2 6.3e-10 0.03 0.11 0.44 FALSE
47 The Cancer Genome Atlas Thyroid Carcinoma ISCA2 0.03 0.02 lasso 3 0.00 2.3e-01 6.4 6.1 1.4e-09 -0.44 0.02 0.03 FALSE
48 The Cancer Genome Atlas Thyroid Carcinoma TTLL5 0.06 0.05 blup 121 0.05 6.3e-06 5.6 -7.0 2.3e-12 0.01 0.94 0.06 FALSE