Best TWAS P=3.76e-18 · Best GWAS P=2.41e-30 conditioned to 3.41e-23
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | TTC27 | 0.17 | 0.00 | enet | 23 | 0.05 | 6.9e-03 | -2.2 | 7.3 | 2.4e-13 | -0.07 | 0.08 | 0.18 | TRUE |
| 2 | GTEx | Artery Tibial | LTBP1 | 0.10 | 0.04 | enet | 12 | 0.03 | 1.5e-03 | -7.6 | 8.2 | 1.9e-16 | -0.11 | 0.80 | 0.05 | FALSE |
| 3 | GTEx | Cells Transformed fibroblasts | LTBP1 | 0.48 | 0.51 | enet | 58 | 0.51 | 2.4e-43 | -7.9 | 8.7 | 3.8e-18 | -0.07 | 1.00 | 0.00 | TRUE |
| 4 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | LTBP1 | 0.21 | 0.08 | lasso | 5 | 0.08 | 1.8e-04 | 4.2 | -6.9 | 6.1e-12 | 0.07 | 0.13 | 0.22 | TRUE |