Best TWAS P=1.34e-15 · Best GWAS P=2.44e-16 conditioned to 0.011
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | NFATC1 | 0.12 | 0.07 | lasso | 5 | 0.07 | 3.5e-11 | -8.2 | -8.0 | 1.3e-15 | 0.87 | 0 | 1 | TRUE |
2 | YFS | Blood | NFATC1 | 0.17 | 0.08 | bslmm | 444 | 0.15 | 3.1e-46 | -5.7 | -5.9 | 3.8e-09 | 0.42 | 1 | 0 | FALSE |