[Hub]/) : Traits : Standing height :

chr19:788,074-6,033,976

Best TWAS P=2.07e-45 · Best GWAS P=1.54e-53 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SIRT6 0.08 0.07 lasso 1 0.07 9.8e-09 -6.02 -6.0 1.7e-09 0.09 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous ANKRD24 0.13 0.08 lasso 4 0.08 5.4e-07 -5.88 -5.7 1.1e-08 0.08 0.88 0.02 FALSE
3 GTEx Adipose Subcutaneous AMH 0.18 0.05 lasso 8 0.06 1.9e-05 -4.01 6.4 1.5e-10 -0.22 0.93 0.00 FALSE
4 GTEx Adipose Subcutaneous NFIC 0.14 0.00 enet 11 0.00 2.7e-01 -0.36 -6.9 7.0e-12 0.01 0.02 0.71 FALSE
5 GTEx Adipose Visceral Omentum NFIC 0.20 0.00 lasso 5 0.02 2.2e-02 9.16 -9.7 5.0e-22 0.07 0.07 0.14 TRUE
6 GTEx Artery Aorta SIRT6 0.20 0.12 lasso 4 0.12 5.2e-07 -5.88 -5.8 8.0e-09 0.11 0.63 0.09 FALSE
7 GTEx Artery Tibial DOT1L 0.09 0.06 lasso 5 0.05 7.3e-05 13.45 12.2 5.0e-34 -0.89 0.03 0.96 FALSE
8 GTEx Artery Tibial NFIC 0.14 0.13 enet 11 0.12 7.6e-10 9.16 -9.1 6.4e-20 0.02 0.76 0.24 FALSE
9 GTEx Brain Cerebellar Hemisphere ANKRD24 0.64 0.16 lasso 6 0.14 1.9e-04 -5.98 -6.2 4.5e-10 0.11 0.28 0.04 TRUE
10 GTEx Breast Mammary Tissue (Male) CTB-50L17.5 0.26 -0.01 enet 23 0.03 7.9e-02 3.94 -6.6 4.9e-11 -0.02 0.04 0.32 FALSE
11 GTEx Cells Transformed fibroblasts ANKRD24 0.14 0.07 enet 30 0.09 1.8e-07 -6.02 -5.5 4.0e-08 0.09 0.90 0.01 FALSE
12 GTEx Colon Sigmoid MAP2K2 0.20 0.11 lasso 3 0.13 3.0e-05 7.04 7.7 2.1e-14 0.00 0.01 0.92 FALSE
13 GTEx Colon Transverse PTPRS 0.17 -0.01 enet 21 0.03 1.9e-02 4.30 -8.2 2.4e-16 -0.01 0.05 0.31 TRUE
14 GTEx Esophagus Mucosa C19orf25 0.13 0.00 enet 19 0.00 6.9e-01 3.35 -5.7 1.2e-08 0.00 0.00 0.01 TRUE
15 GTEx Esophagus Mucosa CTB-50L17.5 0.20 0.04 enet 26 0.07 2.5e-05 6.87 7.2 8.4e-13 -0.01 0.51 0.08 TRUE
16 GTEx Esophagus Muscularis SIRT6 0.14 0.07 lasso 6 0.04 1.4e-03 -5.88 -5.8 6.8e-09 0.09 0.16 0.03 FALSE
17 GTEx Esophagus Muscularis DOT1L 0.12 0.03 lasso 5 0.05 6.3e-04 13.45 8.3 9.1e-17 -0.82 0.01 0.97 TRUE
18 GTEx Esophagus Muscularis NFIC 0.21 0.03 enet 35 0.07 4.9e-05 4.82 -7.0 1.8e-12 0.02 0.07 0.37 FALSE
19 GTEx Lung ANKRD24 0.16 0.13 enet 12 0.12 8.3e-10 -5.93 -5.7 1.4e-08 0.10 1.00 0.00 FALSE
20 GTEx Muscle Skeletal ANKRD24 0.13 0.08 enet 9 0.07 8.1e-08 -5.88 -5.8 7.0e-09 0.10 1.00 0.00 FALSE
21 GTEx Nerve Tibial IZUMO4 0.23 0.07 lasso 6 0.14 1.9e-10 -3.98 -9.2 5.4e-20 0.70 0.03 0.97 FALSE
22 GTEx Nerve Tibial MFSD12 0.17 0.02 lasso 4 0.03 1.8e-03 3.11 -5.4 7.2e-08 -0.04 0.10 0.60 FALSE
23 GTEx Prostate UBXN6 0.27 0.15 enet 19 0.14 2.4e-04 3.81 -6.3 3.0e-10 -0.04 0.12 0.05 TRUE
24 GTEx Skin Sun Exposed Lower leg AC004490.1 0.09 0.07 enet 11 0.10 2.3e-08 -6.26 5.5 3.5e-08 -0.52 0.82 0.12 FALSE
25 GTEx Testis ANKRD24 0.44 0.18 lasso 7 0.19 5.0e-09 -5.93 -5.6 2.1e-08 0.10 0.99 0.00 FALSE
26 GTEx Thyroid SIRT6 0.24 0.20 lasso 5 0.21 3.9e-16 -5.93 -5.8 6.4e-09 0.10 1.00 0.00 FALSE
27 NTR Blood ARRDC5 0.04 0.00 lasso 6 0.01 4.3e-04 10.21 5.7 1.5e-08 -0.07 0.65 0.01 FALSE
28 NTR Blood C19orf35 0.03 0.01 enet 9 0.02 3.7e-07 -2.90 -6.5 9.9e-11 0.38 0.96 0.02 TRUE
29 NTR Blood TMPRSS9 0.04 0.02 lasso 4 0.04 1.3e-11 -1.43 -6.4 1.6e-10 0.33 0.99 0.01 FALSE
30 ROSMAP Brain Pre-frontal Cortex SIRT6 0.24 0.23 lasso 7 0.23 1.2e-29 -5.93 -6.0 2.6e-09 0.09 1.00 0.00 FALSE
31 ROSMAP Brain Pre-frontal Cortex PIAS4 0.14 0.12 lasso 6 0.11 1.6e-13 6.06 6.5 9.1e-11 0.00 1.00 0.00 FALSE
32 YFS Blood ANKRD24 0.04 0.01 lasso 6 0.01 6.0e-05 -5.95 -6.1 8.3e-10 0.09 0.94 0.00 FALSE
33 YFS Blood ARRDC5 0.29 0.19 enet 62 0.24 3.8e-78 10.34 6.2 4.2e-10 -0.09 1.00 0.00 FALSE
34 YFS Blood MAP2K2 0.02 0.00 blup 373 0.01 5.9e-03 -4.74 -6.7 2.5e-11 -0.02 0.01 0.95 TRUE
35 YFS Blood PIAS4 0.06 0.02 bslmm 369 0.04 4.8e-14 6.06 7.8 9.5e-15 0.05 0.57 0.43 TRUE
36 The Cancer Genome Atlas Bladder Urothelial Carcinoma AP3D1 0.05 0.00 blup 49 0.02 1.7e-02 -3.26 6.6 4.1e-11 -0.31 0.03 0.07 TRUE
37 The Cancer Genome Atlas Breast Invasive Carcinoma AP3D1 0.01 0.01 blup 52 0.01 5.4e-03 -3.26 9.5 2.3e-21 -0.54 0.05 0.11 FALSE
38 The Cancer Genome Atlas Breast Invasive Carcinoma JSRP1 0.03 0.01 blup 33 0.01 2.0e-02 -2.90 -5.2 1.7e-07 0.11 0.04 0.09 TRUE
39 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma AMH 0.04 0.03 blup 35 0.02 1.3e-03 -4.01 5.9 4.4e-09 -0.21 0.29 0.11 TRUE
40 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DOT1L 0.08 0.12 enet 8 0.10 2.5e-11 13.45 14.1 2.1e-45 -0.96 0.02 0.98 TRUE
41 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FZR1 0.21 0.07 lasso 3 0.07 5.6e-05 -6.58 -7.5 7.0e-14 0.07 0.00 0.97 FALSE
42 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma JSRP1 0.07 0.04 blup 33 0.03 7.8e-03 -3.98 7.1 1.0e-12 -0.43 0.01 0.11 FALSE
43 The Cancer Genome Atlas Liver Hepatocellular Carcinoma C19orf77 0.16 0.12 lasso 3 0.14 3.6e-07 2.90 5.8 4.8e-09 -0.04 0.36 0.55 FALSE
44 The Cancer Genome Atlas Liver Hepatocellular Carcinoma DOT1L 0.09 0.08 blup 60 0.07 4.1e-04 -10.55 11.5 1.3e-30 -0.87 0.02 0.95 FALSE
45 The Cancer Genome Atlas Lung Squamous Cell Carcinoma JSRP1 0.03 0.00 blup 33 0.02 2.1e-03 -3.02 -7.8 8.4e-15 0.18 0.01 0.26 FALSE
46 The Cancer Genome Atlas Rectum Adenocarcinoma CREB3L3 0.34 0.12 lasso 4 0.13 5.6e-04 -5.88 -6.2 7.5e-10 0.08 0.07 0.09 FALSE
47 The Cancer Genome Atlas Testicular Germ Cell Tumors DOT1L 0.40 -0.01 enet 20 0.03 3.6e-02 -4.60 9.0 2.5e-19 -0.44 0.01 0.21 TRUE
48 The Cancer Genome Atlas Thyroid Carcinoma KDM4B 0.05 0.05 lasso 2 0.04 4.7e-05 7.08 5.3 1.4e-07 -0.03 0.47 0.04 FALSE