TWAS
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Traits
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Standing height
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chr19:6,059,513-7,771,742
Best TWAS P=7.57e-24 · Best GWAS P=6.42e-26 conditioned to 4.02e-07
6M
6.2M
6.4M
6.6M
6.8M
7M
7.2M
7.4M
7.6M
7.8M
0
5
10
15
20
25
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Prostate
ZNF557
0.41
-0.01
lasso
8
0.00
0.273
8.9
10.1
7.6e-24
0.71
0.05
0.10
TRUE
1
GTEx
Lung
SH2D3A
0.16
0.00
enet
43
0.01
0.084
-1.3
5.3
1.1e-07
-0.04
0.09
0.03
TRUE