Best TWAS P=2.22e-07 · Best GWAS P=4.73e-07 conditioned to 1.69e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | LBX2-AS1 | 0.08 | 0.07 | lasso | 4 | 0.04 | 0.00054 | 4.0 | 5.2 | 2.2e-07 | 0.05 | 0.08 | 0.66 | TRUE |
| 2 | GTEx | Colon Transverse | MOGS | 0.13 | 0.01 | enet | 14 | 0.05 | 0.00260 | 4.1 | 5.1 | 2.8e-07 | 0.06 | 0.06 | 0.53 | FALSE |
| 3 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | WDR54 | 0.04 | 0.00 | lasso | 4 | 0.02 | 0.01660 | 4.7 | -5.2 | 2.3e-07 | -0.07 | 0.00 | 0.46 | FALSE |