Best TWAS P=5.37e-12 · Best GWAS P=1.76e-10 conditioned to 0.000478
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | C2orf40 | 0.20 | 0.11 | bslmm | 483 | 0.13 | 7.8e-16 | 3.8 | -6.9 | 5.4e-12 | -0.48 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Muscle Skeletal | C2orf40 | 0.30 | 0.05 | lasso | 6 | 0.14 | 6.2e-14 | -3.0 | -5.5 | 3.2e-08 | -0.36 | 1.00 | 0.00 | FALSE |
| 3 | METSIM | Adipose | C2orf40 | 0.17 | 0.04 | blup | 472 | 0.09 | 1.3e-13 | 3.5 | -5.2 | 1.7e-07 | -0.35 | 0.27 | 0.73 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UXS1 | 0.04 | 0.03 | enet | 4 | 0.02 | 1.1e-03 | -4.4 | -6.8 | 1.2e-11 | -0.45 | 0.03 | 0.31 | FALSE |