Best TWAS P=3.4e-11 · Best GWAS P=7.03e-12 conditioned to 0.00254
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | IL1R1 | 0.14 | 0.09 | lasso | 3 | 0.10 | 4.0e-12 | -5.0 | 5.2 | 2.2e-07 | -0.14 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Heart Atrial Appendage | IL1R1 | 0.13 | 0.04 | enet | 26 | 0.06 | 9.8e-04 | -3.2 | -5.3 | 1.2e-07 | 0.43 | 0.20 | 0.06 | FALSE |
| 3 | YFS | Blood | IL18R1 | 0.19 | 0.10 | blup | 573 | 0.17 | 7.9e-53 | -5.6 | 6.6 | 3.4e-11 | -0.55 | 0.91 | 0.09 | TRUE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | IL1R2 | 0.07 | 0.05 | lasso | 3 | 0.06 | 2.5e-05 | 5.0 | -5.1 | 3.0e-07 | 0.17 | 0.03 | 0.96 | FALSE |