TWAS
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Usage
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Genes
Traits
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Traits
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Standing height
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chr2:101,981,794-103,686,111
Best TWAS P=3.4e-11 · Best GWAS P=7.03e-12 conditioned to 0.00254
102M
102.2M
102.4M
102.6M
102.8M
103M
103.2M
103.4M
103.6M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
YFS
Blood
IL18R1
0.19
0.10
blup
573
0.17
7.9e-53
-5.6
6.6
3.4e-11
-0.55
0.91
0.09
TRUE
1
CommonMind
Brain Pre-frontal Cortex
IL1R1
0.14
0.09
lasso
3
0.10
4.0e-12
-5.0
5.2
2.2e-07
-0.14
1.00
0.00
TRUE
2
GTEx
Heart Atrial Appendage
IL1R1
0.13
0.04
enet
26
0.06
9.8e-04
-3.2
-5.3
1.2e-07
0.43
0.20
0.06
FALSE
4
The Cancer Genome Atlas
Stomach Adenocarcinoma
IL1R2
0.07
0.05
lasso
3
0.06
2.5e-05
5.0
-5.1
3.0e-07
0.17
0.03
0.96
FALSE