Best TWAS P=6.78e-14 · Best GWAS P=3.4e-14 conditioned to 0.0915
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 7.5 | -7.5 | 6.8e-14 | -0.93 | 0.03 | 0.57 | TRUE |
2 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 6.1 | 6.4 | 1.7e-10 | 0.69 | 0.07 | 0.54 | FALSE |
3 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 7.3 | -7.5 | 6.9e-14 | -0.89 | 0.02 | 0.98 | FALSE |