[Hub]/) : Traits : Standing height :

chr4:55,598,706-58,531,645

Best TWAS P=9.95e-20 · Best GWAS P=7.26e-28 conditioned to 3.27e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta NOA1 0.17 0.06 lasso 4 0.06 3.5e-04 6.2 -5.9 3.8e-09 -0.46 0.36 0.23 FALSE
2 GTEx Colon Transverse REST 0.26 0.04 lasso 9 0.10 1.9e-05 -3.6 -7.7 1.2e-14 -0.65 0.03 0.94 FALSE
3 GTEx Muscle Skeletal REST 0.05 0.01 enet 9 0.02 3.9e-03 -3.3 -5.8 7.9e-09 -0.43 0.28 0.60 FALSE
4 GTEx Skin Not Sun Exposed Suprapubic CLOCK 0.08 0.08 lasso 5 0.05 1.4e-03 5.2 5.2 2.4e-07 -0.06 0.02 0.96 FALSE
5 METSIM Adipose RP11-738E22.3 0.07 0.04 lasso 6 0.05 7.7e-08 -5.4 7.1 9.4e-13 0.46 0.85 0.15 TRUE
6 The Cancer Genome Atlas Colon Adenocarcinoma TMEM165 0.06 0.07 enet 11 0.06 2.1e-04 5.1 -5.4 5.3e-08 0.05 0.01 0.96 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma C4orf14 0.03 0.04 lasso 3 0.04 1.9e-05 -6.2 -5.7 1.1e-08 -0.37 0.24 0.21 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CLOCK 0.02 0.02 enet 5 0.02 1.9e-03 4.4 5.2 2.5e-07 -0.03 0.03 0.80 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma REST 0.04 0.01 lasso 5 0.02 7.8e-04 -5.3 -9.1 1.0e-19 -0.70 0.06 0.72 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TMEM165 0.08 0.06 lasso 3 0.09 1.5e-10 5.1 -5.5 4.1e-08 0.03 0.01 0.99 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma TMEM165 0.19 0.16 lasso 4 0.17 2.1e-18 5.2 -5.4 7.1e-08 0.05 0.00 1.00 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma TMEM165 0.05 0.06 enet 5 0.05 4.3e-06 5.1 -5.5 3.4e-08 0.04 0.00 0.99 TRUE