TWAS hub - C4orf14

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	TCGA	Kidney Renal Clear Cell Carcinoma	0.0316	0.0158	6.6e-04	0.044	0.038	0.023	NA	0.041	9.9e-06	3.4e-05	1.1e-03	NA	1.9e-05
2	TCGA	Pheochromocytoma and Paraganglioma	0.1270	0.0640	1.7e-03	0.114	0.083	0.068	NA	0.104	2.9e-05	3.4e-04	1.1e-03	NA	6.2e-05
3	TCGA	Thyroid Carcinoma	0.0740	0.0340	3.8e-06	0.050	0.057	0.048	NA	0.048	1.1e-05	3.2e-06	1.7e-05	NA	1.7e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Ever smoked	14.1	24.8	31.2	-4.6	-5.6	-4.7
Past tobacco smoking	13.9	25.4	28.2	4.5	5.3	5.3
Heel bone mineral density (BMD) T-score, automated (right)	10.5	24.0	35.3	4.6	5.9	3.9
Smoking status: Previous	9.9	14.9	16.8	-3.6	-3.8	-4.1
Heel bone mineral density (BMD) T-score, automated (left)	8.3	18.8	28.0	4.0	5.3	3.5
Heel T-Score	7.8	62.3	89.3	7.9	9.4	5.9
Hearing difficulty/problems: Yes	7.8	11.9	14.8	-2.9	-3.5	-3.8
Forced expiratory volume in 1-second (FEV1)	7.5	25.2	46.8	-6.8	-5.2	-1.2
Smoking Status	7.4	17.7	18.8	-4.0	-4.3	-4.3
Tinnitus: Yes, now most or all of the time	7.4	8.6	11.5	-3.4	-3.1	-2.1
Hearing difficulty/problems with background noise	7.2	11.4	13.4	-3.7	-3.6	-2.9
Respiratory disease	6.5	14.5	20.9	4.6	4.1	2.3
Forced expiratory volume in 1-second (FEV1), Best measure	5.9	18.8	34.7	-5.9	-4.5	-1.4
Forced vital capacity (FVC)	5.5	21.3	38.6	-6.2	-4.9	-1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	5.2	11.0	17.1	-4.1	-3.2	-2.4
Lung FVC	5.0	25.6	34.5	-5.9	-5.2	-4.0
Forced vital capacity (FVC), Best measure	4.7	17.3	31.7	-5.6	-4.4	-1.1
Peak expiratory flow (PEF)	4.5	10.4	18.6	-4.3	-3.4	-0.9
Primary Biliary Cirrhosis	4.3	6.1	8.1	-2.8	-2.8	-1.5
Medication: Paracetamol	4.3	7.2	11.2	3.3	2.9	1.4
Alcohol intake frequency.	4.2	9.8	10.4	3.1	3.2	3.0
Impedance of arm (left)	4.0	18.6	34.7	1.1	4.4	5.9
Alzheimer’s Disease (including proxy)	3.9	5.6	7.6	-2.2	-2.1	-2.8
Type 2 Diabetes (T2D) (2018)	3.9	7.3	10.0	-2.5	-2.4	-3.2
Father’s age at death	3.9	5.3	7.7	2.4	2.8	1.6
Mean time to correctly identify matches	3.9	7.4	9.7	2.7	3.1	2.3
Alzheimer’s Disease (in mother)	3.8	4.4	5.3	-2.1	-2.3	-1.9
Impedance of arm (right)	3.8	17.8	35.5	0.6	4.2	6.0
Had major operations	3.8	4.4	5.5	-1.6	-2.3	-2.2
Medication for cholesterol, blood pressure or diabetes	3.7	6.2	11.0	1.0	2.6	3.3
Reaction Time	3.6	6.9	8.1	2.8	2.8	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	3.6	4.6	6.2	-2.3	-2.5	-1.6
Friendships satisfaction	3.6	4.4	5.1	-2.3	-2.0	-2.1
Impedance of whole body	3.6	18.1	29.4	1.5	4.8	5.4
Loud music exposure frequency	3.5	3.9	4.5	-1.8	-2.0	-2.1
Headache pain in last month	3.4	5.8	7.6	2.8	2.7	1.5
Risk taking	3.4	4.9	8.5	-0.9	-2.3	-2.9
Blood White Count	3.3	24.3	46.8	6.8	4.8	-1.7
Breastfed as a baby	3.2	3.9	4.4	-2.1	-1.9	-1.9
Ever taken oral contraceptive pill	3.2	3.6	4.9	-2.2	-1.3	-2.0
Blood Platelet Count	3.1	35.5	63.5	8.0	5.5	-3.6
Commuting to job workplace: Cycle	3.1	3.7	4.6	-2.1	-1.5	-2.1
Gout (self-reported)	3.0	4.2	5.5	-2.0	-1.8	-2.4
Financial difficulties in last 2 years	2.7	3.6	5.9	-2.4	-2.1	-0.6
High blood pressure (siblings)	2.7	3.9	4.7	-1.8	-2.2	-1.9
Qualifications: CSEs or equivalent	2.6	3.5	5.1	2.3	1.6	1.7
Exposure to tobacco smoke at home	2.6	2.9	3.9	-1.6	-2.0	-1.5
Medication: Allopurinol	2.6	3.4	3.8	-2.0	-1.8	-1.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.6	3.1	4.6	2.1	2.1	0.6
Asthma	2.5	4.9	8.2	2.9	2.3	1.0
Alcohol drinker status: Never	2.5	3.0	3.8	1.2	1.9	1.9
Medication: Atorvastatin	2.4	3.0	3.3	1.6	1.8	1.8
Lung FEV1/FVC ratio	2.3	11.6	20.6	-4.5	-3.5	-1.3
Had other major operations	2.3	2.8	4.4	-2.0	-2.1	0.1
Trunk fat-free mass	2.3	13.2	20.5	-4.1	-4.5	-1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	2.3	3.5	5.2	-2.2	-2.3	-0.4
Medication: Blood pressure	2.3	4.1	8.4	-0.6	-1.9	-2.9
Asthma (self-reported)	2.3	4.7	8.0	2.8	2.3	0.7
Average weekly beer plus cider intake	2.3	3.4	4.2	-1.6	-2.0	-1.9
Blood Eosinophil Count	2.2	17.0	30.2	5.5	4.5	0.5
Medication: Co-codamol	2.2	2.5	4.3	2.1	1.7	0.6
Supplements: Glucosamine	2.2	2.9	5.8	-2.4	-1.2	-1.1
Trunk predicted mass	2.2	12.4	19.4	-4.0	-4.4	-1.3
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.6	4.4	-2.1	-1.5	-1.1
Maternal smoking around birth	2.1	3.1	4.8	-1.4	-1.6	-2.2
High blood pressure	2.1	5.8	9.7	-1.1	-2.5	-3.1
Pain all over the body in last month	2.1	2.2	3.5	1.9	1.2	1.3
Arm fat-free mass (right)	2.1	10.8	17.4	-3.3	-4.2	-2.1
Medication: Omeprazole	2.1	2.5	5.4	-0.6	-1.3	-2.3
Average weekly red wine intake	2.1	3.1	5.1	-2.2	-1.5	-1.5
Vascular/heart problems diagnosed by doctor	2.1	5.8	7.9	1.3	2.8	2.8
Schizophrenia vs Biploar Disorder	2.0	2.6	3.7	-1.9	-1.7	-1.1
Height	2.0	38.6	63.0	-7.9	-4.7	5.5
Allergy	2.0	4.7	5.9	-2.4	-1.9	-2.2
Medication for pain relief, constipation, heartburn	2.0	3.4	6.7	-2.6	-1.8	-0.4
Comparative height size at age 10	2.0	11.0	27.8	-2.3	0.3	5.3
Osteoporosis (self-reported)	2.0	2.5	3.2	-1.8	-1.6	-1.3
Fractured/broken bones in last 5 years	2.0	2.5	4.6	-2.1	-1.7	-0.2
Arm predicted mass (left)	2.0	10.1	15.8	-3.4	-4.0	-1.7
Depression (Nagel 2018)	1.9	2.9	3.6	-1.5	-1.9	-1.7
Standing height	1.9	19.1	32.6	-5.7	-2.9	4.0
Medication: Ibuprofen	1.9	2.3	3.6	1.6	1.9	0.9
Arm predicted mass (right)	1.9	9.9	16.4	-3.2	-4.0	-1.8
Medication: Paracetamol	1.9	3.0	5.7	2.4	1.8	0.2
Ever had prostate specific antigen (PSA) test	1.9	2.2	2.5	-1.3	-1.5	-1.6
Alzheimer’s Disease (in father)	1.8	2.0	3.1	-1.4	-0.9	-1.8
Medication: Aspirin	1.8	2.4	3.3	-1.5	-1.8	-1.3
Hypertension (Self-reported)	1.8	5.1	9.3	-0.7	-2.3	-3.0
Whole body fat-free mass	1.8	10.4	17.1	-3.6	-4.1	-1.0
Medication: Aspirin	1.8	2.4	3.2	-1.4	-1.8	-1.4
Whole body water mass	1.8	10.5	17.2	-3.6	-4.2	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	3.1	-1.2	-1.8	-1.5
Medication: Ventolin 100micrograms inhaler	1.7	2.2	3.1	1.8	1.3	1.3
Average weekly champagne plus white wine intake	1.7	2.4	2.5	-1.6	-1.5	-1.6
Number of operations (self-reported)	1.7	2.5	3.9	-1.9	-2.0	-0.4
Bipolar Disorder (2011)	1.6	1.6	2.7	0.3	1.6	1.4
Medication: Simvastatin	1.6	2.4	3.5	-1.1	-1.6	-1.9
Pulse rate	1.6	2.6	4.4	2.1	1.7	0.8
Chronic bronchitis/emphysema (mother)	1.6	1.9	3.0	1.6	1.7	0.4
Neck or shoulder pain in last month	1.6	2.2	2.8	1.2	1.5	1.7
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	2.9	-1.3	-1.7	-0.8
Basal metabolic rate	1.6	8.8	13.8	-3.4	-3.7	-0.9
Arm fat-free mass (left)	1.6	8.2	13.3	-3.1	-3.6	-1.3
Diastolic blood pressure, automated reading	1.6	4.8	11.6	-0.1	-1.7	-3.4
Ulcerative Colitis (UC)	1.5	2.7	6.6	1.0	0.7	2.6
Breast Cancer	1.5	3.6	8.6	-1.3	-0.7	-2.9
Angina	1.5	2.0	5.0	-0.9	-0.4	2.2
Age when periods started (menarche)	1.5	3.5	4.9	-2.1	-2.2	-1.1
Hair/balding pattern: Pattern 2	1.5	1.9	3.1	-1.8	-1.6	-0.4
Hayfever/allergic rhinitis (self-reported)	1.5	1.9	3.6	1.4	0.5	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	2.6	1.6	1.6	0.8
Medication: Cholesterol lowering	1.5	2.4	3.2	-1.4	-1.8	-1.5
Worry too long after embarrassment	1.5	2.5	3.6	-1.7	-1.9	-1.0
Health satisfaction	1.5	1.9	3.0	1.6	1.7	0.3
Angina (self-reported)	1.5	2.0	4.5	-1.1	-0.4	2.1
Mother’s age at death	1.5	1.9	3.3	-1.0	-1.1	-1.8
Irritability	1.5	2.6	4.9	-0.9	-2.2	-1.5
Intelligence (Savage-Jansen 2018)	1.4	4.4	7.0	-2.4	-2.6	-0.6
Impedance of leg (left)	1.4	7.0	10.7	0.5	3.2	3.3
Coronary Artery Disease (CAD)	1.3	1.6	3.5	-1.1	-1.9	-0.3
Mean Putamen Volume	1.3	1.5	2.2	-0.7	-1.3	-1.5
Relative age of first facial hair	1.3	2.7	7.7	0.5	-0.5	-2.8
Medication for hormone replacement therapy	1.3	1.5	3.1	1.8	1.0	0.6
Number of incorrect matches in round	1.3	2.2	4.0	0.4	1.6	2.0
Time employed in main current job	1.3	1.5	2.0	1.3	1.4	0.8
Number of live births	1.3	1.8	2.9	-1.7	-1.3	-0.9
Long-standing illness, disability or infirmity	1.3	2.0	3.6	1.9	1.2	0.9
Unable to work because of sickness or disability	1.3	1.7	2.0	-1.4	-1.4	-1.0
Deep venous thrombosis (DVT) (self-reported)	1.3	1.7	4.4	-0.1	0.8	2.1
HbA1C	1.2	1.3	2.7	-1.1	-0.0	1.6
Impedance of leg (right)	1.2	5.7	9.2	0.1	2.8	3.0
Leg fat-free mass (left)	1.2	6.3	10.8	-2.8	-3.3	-0.5
Birth weight of first child	1.2	2.1	2.6	1.6	1.4	1.4
Blood clot in the leg (DVT)	1.2	1.5	4.0	-0.2	0.7	2.0
Illnesses of siblings: Diabetes	1.2	1.4	2.3	1.0	1.5	1.0
Leg fat-free mass (right)	1.2	6.2	10.9	-2.7	-3.3	-0.3
Taking other prescription medications	1.1	1.7	2.3	-1.5	-1.4	-0.9
Bilateral oophorectomy (both ovaries removed)	1.1	1.3	2.8	1.7	1.0	0.4
Leg predicted mass (left)	1.1	6.0	10.3	-2.7	-3.2	-0.5
Alcohol usually taken with meals	1.1	1.8	3.0	0.8	1.3	1.7
Medication: Ramipril	1.1	1.4	2.3	-0.3	-1.5	-1.4
Pulse rate, automated reading	1.1	3.4	8.1	2.8	1.5	-0.2
Ever had bowel cancer screening	1.1	1.3	2.0	0.8	1.1	1.4
Leg predicted mass (right)	1.1	5.9	10.6	-2.7	-3.3	-0.3
Myopia	1.1	1.5	2.1	1.4	0.8	1.4
Bipolar Disorder (2018)	1.0	1.6	3.2	0.6	1.1	1.8
Body Mass Index (BMI) (2010)	1.0	1.3	1.7	-0.9	-1.2	-1.3
Neuroticism	1.0	2.4	3.9	-1.3	-2.0	-1.3
Sitting height	1.0	7.4	16.4	-2.3	-0.6	4.0
Depression (self-reported)	1.0	1.2	1.9	-0.8	-1.4	-1.1
Emphysema/chronic bronchitis	1.0	1.1	2.0	1.4	1.1	0.2
Heart disease (mother)	1.0	1.3	2.0	1.0	1.0	1.4
Illnesses of father: Heart disease	1.0	1.4	2.5	-1.6	-1.3	0.3
Commuting to job workplace: Walk	1.0	1.1	2.4	-0.5	-0.8	-1.6
Medication: Lisinopril	1.0	1.3	1.7	-1.3	-0.8	-1.3
Cardiovascular Disease	0.9	3.1	6.9	0.3	-1.5	-2.6
Frequency of depressed mood in last 2 weeks	0.9	1.3	2.0	-1.1	-1.4	-0.9
Average weekly fortified wine intake	0.9	1.0	1.2	-1.1	-1.0	-0.9
Medication: Levothyroxine sodium	0.9	1.5	4.0	2.0	0.6	0.3
Chronic bronchitis/emphysema (father)	0.9	1.0	2.4	1.6	0.6	-0.6
Ever unenthusiastic/disinterested for a whole week	0.9	1.2	2.2	-1.5	-1.1	-0.1
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	1.9	1.4	1.1	0.4
Heart disease (siblings)	0.9	1.2	1.5	-1.1	-1.2	0.9
Alcohol drinker status: Previous	0.9	1.0	1.7	1.3	0.7	0.9
Hand grip strength (left)	0.8	2.0	3.5	-1.6	-1.9	-0.5
Systolic blood pressure, automated reading	0.8	2.3	5.9	0.5	-1.0	-2.4
Trunk fat percentage	0.8	3.0	5.3	0.7	2.3	1.8
Relative age voice broke	0.8	1.3	3.2	0.4	-0.6	-1.8
Mouth/teeth dental problems: Dentures	0.8	1.4	3.1	0.5	-0.9	-1.8
Eye problems/disorders: Cataract	0.8	1.0	2.1	-1.4	-0.6	-0.7
Osteoarthritis (self-reported)	0.8	1.1	2.5	0.4	1.6	0.8
Medication: Blood pressure	0.8	1.6	2.6	-1.1	-1.6	-1.0
Fasting Glucose	0.7	0.8	1.1	-0.6	-1.0	-1.0
Systolic Blood Pressure	0.7	3.4	6.7	0.3	-1.9	-2.6
Hair Pigment	0.7	18.9	28.0	-5.3	-5.1	-1.6
Tanning	0.7	8.8	13.8	-2.2	-2.8	-3.7
Average weekly spirits intake	0.7	0.8	1.9	0.2	-0.7	-1.4
Heart attack	0.7	0.9	1.4	-1.1	-1.2	0.2
Diabetes (self-reported)	0.7	1.1	3.1	0.2	0.2	-1.8
Weight	0.7	3.3	6.0	-2.4	-1.9	-0.1
Hair/balding pattern: Pattern 4	0.7	1.6	2.6	-1.6	-0.7	1.4
Wheeze or whistling in the chest in last year	0.7	1.3	2.5	1.6	1.0	0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	1.5	0.4	1.0	1.2
Suffer from ‘nerves’	0.7	1.0	1.6	1.1	0.6	1.3
Leg pain on walking	0.7	0.9	1.0	1.0	0.9	-0.9
Diabetes diagnosed by doctor	0.7	1.1	3.4	-0.3	-0.0	-1.8
Hearing aid user	0.7	0.8	0.9	-0.8	-1.0	-0.9
Eye problems/disorders: Glaucoma	0.7	0.8	1.2	-1.1	-0.2	-1.1
Supplements: Calcium	0.7	0.8	1.4	-1.0	-1.2	0.1
Medication: Metformin	0.6	0.9	1.4	-0.8	-0.8	-1.2
Hand grip strength (right)	0.6	1.7	2.7	-1.3	-1.6	-0.9
Falls in the last year	0.6	0.8	2.2	-0.4	0.2	1.5
Hair/balding pattern: Pattern 3	0.6	0.9	1.4	1.0	0.7	-1.2
Tense / ‘highly strung’	0.6	0.9	1.9	-0.4	-0.9	-1.4
Glaucoma (self-reported)	0.6	0.8	1.3	-1.2	-0.3	-0.9
Medication: Seretide 50 evohaler	0.6	0.7	1.1	0.5	1.0	0.8
Overall health rating	0.6	1.2	2.8	1.7	0.5	0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	0.9	1.3	-1.0	-1.1	0.6
Medication for cholesterol	0.6	1.0	1.5	0.7	0.9	1.2
Breast cancer (self-reported)	0.6	0.8	1.2	-1.1	-0.9	-0.4
Illnesses of father: None of the above (group 1)	0.6	0.8	1.2	0.8	0.8	1.1
Age started oral contraceptive pill	0.6	0.7	1.4	0.8	1.2	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.8	-0.2	-0.6	-1.3
Heart attack/myocardial infarction (self-reported)	0.6	0.7	1.1	-1.0	-1.1	0.2
Depressed Affect (Nagel 2018)	0.5	1.1	1.6	-0.5	-1.3	-1.2
Irritable Bowel Disease (IBD)	0.5	1.2	3.3	0.1	-0.6	1.8
Major Depression (MDD)	0.5	0.6	1.3	-1.1	-0.7	-0.2
Verbal and Numeric Reasoning (VNR)	0.5	1.2	2.4	-1.1	-1.5	0.3
Ovarian Cancer	0.5	0.6	1.1	-0.4	-0.8	-1.1
LDL Cholesterol	0.5	0.7	2.0	0.0	0.5	1.4
BMI	0.5	2.9	6.7	-0.5	-1.3	-2.6
Pack years adult smoking proportion	0.5	0.7	1.8	1.3	0.4	-0.4
Hayfever, allergic rhinitis or eczema	0.5	1.1	2.0	1.0	0.4	1.4
Worrier / anxious feelings	0.5	1.0	2.1	1.5	0.4	0.8
Length of working week for main job	0.5	0.6	1.0	1.0	0.0	-0.8
Body fat percentage	0.5	1.9	4.0	0.8	2.0	1.0
Number of full brothers	0.5	0.7	0.8	0.8	0.8	0.9
Pulse wave peak to peak time	0.5	0.5	0.7	-0.8	-0.6	0.9
Qualifications: College or University degree	0.5	1.6	2.0	-1.1	-1.2	-1.4
Eye problems/disorders: None of the above	0.5	0.6	1.8	1.3	0.1	0.1
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.1	0.9	1.0	0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	1.7	1.3	-0.1	-0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	0.9	0.9	0.9	0.5
Back pain experienced in last month	0.5	0.7	1.1	-1.0	-1.0	0.3
Mineral and other dietary supplements	0.5	0.7	2.0	1.4	0.3	0.1
Smoking status: Current	0.5	0.8	1.6	-0.2	-0.9	-1.2
Guilty feelings	0.5	0.8	1.7	-1.3	-0.8	-0.2
Financial situation satisfaction	0.5	0.6	1.1	-1.1	-0.7	-0.3
Pain experienced in last month	0.5	0.9	1.1	-1.0	-0.9	-1.0
Basal cell carcinoma (self-reported)	0.5	0.5	1.6	-0.2	0.1	1.2
Neuroticism (Nagel 2018)	0.4	0.8	1.7	-0.8	-1.3	-0.3
Crohns Disease (2017)	0.4	0.9	1.5	-0.9	-1.2	0.7
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.2	-1.1	-0.3	-0.4
Blood Red Count	0.4	3.6	8.2	2.9	1.6	0.4
Diverticular disease/diverticulitis (self-reported)	0.4	0.5	0.7	0.8	0.7	0.6
Medication: Atenolol	0.4	0.5	0.6	0.6	0.7	0.8
High blood pressure (mother)	0.4	0.5	1.4	0.3	-0.1	-1.2
Body mass index (BMI)	0.4	1.7	4.5	0.1	-0.7	-2.1
Serious illness, injury or assault of a close relative in last 2 years	0.4	0.4	1.0	-1.0	-0.6	-0.1
Illnesses of mother	0.4	0.5	1.0	0.2	0.5	1.0
Number of children fathered	0.4	0.5	1.1	-0.6	-0.2	-1.1
Chest pain or discomfort	0.4	0.6	1.7	0.1	0.1	1.3
Commuting to job workplace: Car/motor vehicle	0.4	0.5	0.7	-0.8	-0.3	0.9
Qualifications: nursing, teaching	0.4	0.6	0.9	0.9	0.2	-0.9
Medication: Bendroflumethiazide	0.4	0.6	1.5	0.3	-0.6	-1.2
Leg fat percentage (left)	0.4	1.3	3.0	1.0	1.7	-0.2
Crohns Disease (2012)	0.3	0.5	0.7	-0.8	-0.5	0.9
Allergy or Eczema	0.3	0.8	1.2	1.1	0.4	1.1
Ever used hormone-replacement therapy (HRT)	0.3	0.3	0.8	-0.9	-0.4	-0.1
Ever had hysterectomy (womb removed)	0.3	0.3	0.7	-0.1	-0.4	-0.9
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	0.8	0.1	-0.2	-0.9
Fed-up feelings	0.3	0.5	0.8	0.8	0.2	-0.9
Stomach or abdominal pain in last month	0.3	0.4	0.5	-0.7	-0.6	-0.4
Qualifications: None of the above	0.3	0.7	2.0	1.4	0.4	-0.2
Pulse wave Arterial Stiffness index	0.3	0.3	0.4	0.7	0.6	-0.5
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.7	0.4	-0.8	-0.3
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.1	1.0	0.4	0.2
Leg fat percentage (right)	0.3	0.9	2.2	0.7	1.5	-0.3
Comparative body size at age 10	0.3	0.8	2.5	0.2	-0.1	-1.6
Number of full sisters	0.3	0.4	0.6	-0.7	-0.8	-0.4
Supplements: Vitamin C	0.3	0.4	0.6	-0.7	0.3	0.8
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.6	1.3	-1.1	-0.1	0.8
Medication: Gliclazide	0.3	0.4	0.8	0.6	0.0	-0.9
Miserableness	0.3	0.5	1.1	-0.2	-0.7	-1.1
Commuting to job workplace: Public transport	0.3	0.4	0.5	0.7	0.7	0.5
Supplements: Fish oil (including cod liver oil)	0.3	0.3	0.8	-0.9	-0.3	-0.2
Illnesses of father: High blood pressure	0.3	0.4	0.5	-0.7	-0.7	-0.5
Ever depressed for a whole week	0.3	0.3	0.6	-0.6	-0.8	0.1
Pack years of smoking	0.3	0.4	0.9	1.0	0.3	-0.5
Bipolar Disorder or Schizophrenia	0.2	0.4	0.7	0.9	0.5	0.4
Schizophrenia (2018)	0.2	0.4	1.0	0.6	-0.2	-1.0
Age at First Birth	0.2	0.3	0.9	-0.3	-0.1	-0.9
Neuroticism (2016)	0.2	0.3	0.5	-0.7	-0.6	0.4
Rheumatoid Arthritis	0.2	0.2	0.3	-0.5	-0.5	0.5
Schizophrenia (2014)	0.2	0.4	0.7	0.8	0.5	-0.5
Ulcerative Colitis	0.2	0.4	0.7	0.5	-0.2	0.8
Waist Hip Ratio (WHR)	0.2	0.9	1.0	-1.0	-0.9	0.9
Chronotype (morning person)	0.2	0.4	0.8	0.6	0.9	0.0
Number of treatments/medications taken	0.2	0.4	0.9	0.4	-0.2	-0.9
Sensitivity / hurt feelings	0.2	0.3	0.4	-0.6	-0.4	0.6
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.9	0.3	0.1	0.9
Vitamin and mineral supplements	0.2	0.3	0.7	0.8	0.2	-0.3
Supplements: Zinc	0.2	0.3	0.5	0.5	0.2	-0.7
Diabetes (father)	0.2	0.3	0.6	0.4	0.8	-0.1
Diabetes (mother)	0.2	0.2	0.3	0.4	0.5	-0.5
Severe depression (siblings)	0.2	0.2	0.5	0.2	0.1	-0.7
Townsend deprivation index at recruitment	0.2	0.2	0.6	0.8	0.3	-0.1
Current tobacco smoking	0.2	0.4	0.7	0.1	-0.7	-0.8
Serious illness, injury or assault to yourself	0.2	0.2	0.5	-0.7	-0.3	-0.1
Fluid intelligence score	0.2	0.3	0.8	-0.4	-0.9	-0.0
Illnesses of siblings	0.2	0.3	0.4	0.6	0.7	0.3
Hip circumference	0.2	1.1	1.8	0.6	1.4	1.0
Noisy workplace	0.2	0.2	0.6	-0.7	-0.3	-0.1
Qualifications: A levels/AS levels or equivalent	0.2	0.5	0.8	-0.9	-0.5	-0.7
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.7	0.6	-0.3	0.8
Medication: Amlodipine	0.2	0.3	0.4	-0.1	-0.6	-0.7
Birth weight	0.2	0.4	1.0	1.0	-0.0	0.5
Shortness of breath walking on level ground	0.2	0.2	0.6	0.8	-0.1	-0.3
Leg fat mass (right)	0.2	0.8	1.2	-0.9	-0.6	-1.1
Age at last live birth	0.2	0.3	0.5	0.7	0.2	0.6
Arm fat percentage (left)	0.2	0.7	1.8	0.6	1.4	0.3
Mood swings	0.2	0.3	0.9	0.9	-0.1	0.4
Number of self-reported non-cancer illnesses	0.2	0.4	0.7	0.1	-0.8	-0.7
Wears glasses or contact lenses	0.2	0.2	0.3	-0.4	0.2	0.6
Leg fat mass (left)	0.2	0.7	1.1	-0.9	-0.6	-1.0
Worry (Nagel 2018)	0.1	0.3	0.4	0.6	0.2	0.6
HDL Cholesterol	0.1	0.2	0.6	-0.8	0.0	-0.1
Lupus	0.1	0.1	0.3	0.1	-0.6	-0.2
Hypothyroidism (self reported)	0.1	0.2	0.4	-0.6	-0.4	0.4
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	0.4	0.4	0.0
Multivitamins +/- minerals	0.1	0.1	0.3	-0.5	-0.0	0.1
Trunk fat mass	0.1	0.6	1.0	-0.6	0.7	1.0
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.1	0.3	0.2	-0.6	-0.1
Mouth/teeth dental problems	0.1	0.2	0.3	-0.1	0.5	0.4
Neuroticism score	0.1	0.1	0.3	-0.2	-0.6	-0.1
Arm fat percentage (right)	0.1	0.5	1.4	0.2	1.2	0.2
Alcohol intake versus 10 years previously	0.1	0.2	0.3	0.2	-0.4	-0.5
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.3	-0.1	-0.5	0.2
Happiness	0.1	0.1	0.3	0.5	0.3	0.2
Medication: Lansoprazole	0.1	0.1	0.3	-0.2	-0.5	0.2
Prospective memory result	0.1	0.2	0.4	0.1	-0.6	-0.4
Arm fat mass (right)	0.1	0.5	1.0	-1.0	-0.5	-0.4
Pulse wave reflection index	0.1	0.2	0.3	0.6	0.4	0.1
Qualifications: O levels/GCSEs or equivalent	0.1	0.1	0.2	0.2	-0.1	0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.2	-0.0	0.3	0.4
Age at first live birth	0.1	0.2	0.5	0.1	-0.1	0.7
Whole body fat mass	0.1	0.3	0.9	-0.9	-0.1	-0.0
Family relationship satisfaction	0.1	0.1	0.3	-0.1	-0.3	0.5
Knee pain experienced in last month	0.1	0.1	0.3	-0.5	-0.2	0.0
Loneliness, isolation	0.1	0.1	0.2	0.4	0.2	0.2
Arm fat mass (left)	0.1	0.4	0.7	-0.8	-0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.4	-0.1	0.6	0.1
High cholesterol (Self-reported)	0.1	0.1	0.2	0.1	-0.2	-0.5
Prostate Cancer	0.0	0.0	0.1	0.2	0.3	0.1
Triglycerides	0.0	0.1	0.2	0.1	0.0	0.4
Waist circumference	0.0	0.1	0.1	0.3	0.3	0.3
Nervous feelings	0.0	0.1	0.1	0.1	0.3	0.3
Had menopause	0.0	0.1	0.1	-0.2	0.0	0.4
Lung cancer (father)	0.0	0.0	0.0	-0.1	-0.2	0.1
Exposure to tobacco smoke outside home	0.0	0.1	0.1	0.3	-0.1	0.3
Migraine (self-reported)	0.0	0.1	0.1	-0.0	-0.3	-0.2
Cholesterol lowering medication	0.0	0.0	0.1	-0.1	0.2	0.3

Hub : Genes

C4orf14

Models

Trait associations