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chr6:25,266,147-26,689,223

Best TWAS P=3.82e-20 · Best GWAS P=6.57e-92 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
4	GTEx	Artery Tibial	TRIM38	0.08	0.00	lasso	9	0.00	3.7e-01	8.5	9.2	3.8e-20	-0.28	0.31	0.03	TRUE
8	GTEx	Esophagus Gastroesophageal Junction	U91328.20	0.16	0.13	enet	16	0.13	2.0e-05	-3.5	9.0	1.5e-19	-0.31	0.45	0.03	TRUE
3	GTEx	Artery Aorta	U91328.21	0.18	0.00	lasso	11	0.02	3.5e-02	-2.9	8.0	1.1e-15	-0.09	0.18	0.04	TRUE
15	GTEx	Ovary	U91328.19	0.37	0.17	enet	18	0.34	4.7e-09	-3.5	6.9	4.8e-12	-0.37	0.75	0.02	TRUE
9	GTEx	Esophagus Gastroesophageal Junction	U91328.19	0.28	0.07	lasso	7	0.21	4.3e-08	-3.5	6.8	1.1e-11	-0.32	0.71	0.02	TRUE
12	GTEx	Esophagus Muscularis	U91328.19	0.36	0.30	lasso	10	0.30	1.7e-18	-5.6	6.5	6.9e-11	-0.30	1.00	0.00	TRUE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC17A1	0.08	0.06	lasso	5	0.06	1.3e-07	6.0	-5.6	2.0e-08	0.13	0.16	0.84	TRUE
6	GTEx	Brain Cerebellum	U91328.19	0.13	0.15	lasso	2	0.09	1.1e-03	-5.8	5.6	2.6e-08	-0.31	0.35	0.06	TRUE
10	GTEx	Esophagus Mucosa	U91328.19	0.45	0.42	lasso	7	0.44	6.3e-32	-4.1	5.5	3.7e-08	-0.31	1.00	0.00	TRUE
16	GTEx	Thyroid	U91328.21	0.08	0.04	lasso	3	0.05	5.5e-05	-2.6	5.3	1.3e-07	-0.21	0.74	0.01	TRUE
19	METSIM	Adipose	U91328.20	0.07	0.04	bslmm	658	0.04	8.9e-07	-5.8	9.0	2.1e-19	-0.46	0.93	0.02	FALSE
20	YFS	Blood	TRIM38	0.37	0.31	bslmm	672	0.34	3.8e-115	-5.8	-8.3	1.5e-16	0.15	1.00	0.00	FALSE
17	GTEx	Whole Blood	TRIM38	0.08	0.04	enet	13	0.03	1.4e-03	7.8	8.0	1.2e-15	-0.29	0.79	0.01	FALSE
18	GTEx	Whole Blood	U91328.21	0.07	0.04	lasso	4	0.04	1.7e-04	7.8	7.9	3.7e-15	-0.24	0.40	0.02	FALSE
11	GTEx	Esophagus Muscularis	TRIM38	0.06	0.04	lasso	4	0.02	1.7e-02	-5.6	7.8	5.1e-15	-0.31	0.53	0.04	FALSE
1	GTEx	Adrenal Gland	U91328.19	0.28	0.12	lasso	10	0.14	1.3e-05	-5.3	7.7	1.1e-14	-0.30	0.95	0.00	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC17A3	0.03	0.01	lasso	2	0.01	4.9e-02	6.1	-6.6	3.4e-11	0.20	0.03	0.79	FALSE
5	GTEx	Brain Cerebellar Hemisphere	U91328.19	0.47	0.33	enet	44	0.26	2.8e-07	-5.3	6.1	8.6e-10	-0.34	0.98	0.00	FALSE
13	GTEx	Lung	TRIM38	0.09	0.03	lasso	4	0.05	1.3e-04	9.4	5.9	3.5e-09	-0.14	0.49	0.03	FALSE
2	GTEx	Artery Aorta	U91328.19	0.32	0.24	lasso	7	0.25	8.3e-14	-5.6	5.8	6.0e-09	-0.32	1.00	0.00	FALSE
7	GTEx	Colon Transverse	TRIM38	0.15	0.00	enet	43	0.03	1.7e-02	-1.5	5.6	1.7e-08	-0.19	0.15	0.05	FALSE
14	GTEx	Lung	U91328.19	0.20	0.22	enet	15	0.24	2.9e-18	-5.5	5.5	3.3e-08	-0.31	1.00	0.00	FALSE