[Hub]/) : Traits : Standing height : ← →

chr6:33,662,667-36,897,763

Best TWAS P=3e-90 · Best GWAS P=7.31e-109 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
34	GTEx	Nerve Tibial	C6orf106	0.11	0.07	enet	17	0.07	1.3e-05	18.54	20.1	3.9e-90	0.03	0.71	0.02	TRUE
91	The Cancer Genome Atlas	Thyroid Carcinoma	C6orf106	0.08	0.00	enet	15	0.05	2.5e-05	-8.82	19.8	1.1e-87	-0.05	0.03	0.30	TRUE
71	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C6orf106	0.04	0.01	blup	68	0.01	2.4e-02	18.87	18.5	1.7e-76	0.08	0.01	0.72	TRUE
58	ROSMAP	Brain Pre-frontal Cortex	PACSIN1	0.09	0.00	blup	359	0.02	4.5e-04	18.65	18.0	2.4e-72	0.27	0.18	0.07	TRUE
24	GTEx	Esophagus Mucosa	RPL10A	0.14	0.10	enet	17	0.09	2.1e-06	-10.36	-13.4	6.7e-41	-0.12	0.92	0.02	TRUE
72	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	RPL10A	0.07	0.07	lasso	2	0.06	9.9e-08	-10.36	-10.8	2.5e-27	-0.04	1.00	0.00	TRUE
80	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf81	0.05	0.00	blup	43	0.02	8.9e-04	8.34	-8.3	1.5e-16	0.03	0.03	0.03	TRUE
36	GTEx	Ovary	MAPK13	0.23	-0.01	enet	40	0.02	8.7e-02	3.91	8.1	8.0e-16	0.06	0.08	0.05	TRUE
42	GTEx	Skin Sun Exposed Lower leg	SRPK1	0.14	0.00	enet	27	0.02	1.2e-02	-0.51	8.0	1.7e-15	0.14	0.22	0.11	TRUE
84	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	CLPS	0.26	0.08	enet	14	0.10	4.9e-07	2.52	-6.9	6.1e-12	-0.02	0.59	0.03	TRUE
5	CommonMind	Brain Pre-frontal Cortex	TAF11	0.18	0.09	lasso	7	0.11	6.4e-13	-8.35	-6.4	1.5e-10	0.00	1.00	0.00	TRUE
89	The Cancer Genome Atlas	Prostate Adenocarcinoma	TCP11	0.03	0.03	lasso	3	0.04	3.8e-05	-6.26	-6.3	2.5e-10	0.13	0.23	0.20	TRUE
19	GTEx	Cells Transformed fibroblasts	RPS10	0.12	0.05	lasso	4	0.06	4.5e-05	7.28	6.2	7.6e-10	0.09	0.98	0.00	TRUE
12	GTEx	Brain Cerebellum	MAPK13	0.42	0.05	enet	19	0.31	5.7e-10	4.10	6.0	1.4e-09	0.10	0.78	0.01	TRUE
59	ROSMAP	Brain Pre-frontal Cortex	C6orf106	0.30	0.26	bslmm	372	0.33	9.3e-44	18.98	20.1	3.0e-90	0.00	1.00	0.00	FALSE
53	NTR	Blood	C6orf106	0.03	0.02	lasso	6	0.02	7.2e-07	18.98	20.0	5.7e-89	0.05	1.00	0.00	FALSE
83	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C6orf106	0.14	0.07	enet	6	0.06	1.0e-04	18.98	19.1	4.5e-81	0.08	0.01	0.98	FALSE
75	The Cancer Genome Atlas	Brain Lower Grade Glioma	C6orf106	0.04	0.05	lasso	4	0.03	8.1e-05	18.94	18.6	2.8e-77	0.09	0.01	0.99	FALSE
13	GTEx	Brain Cortex	C6orf106	0.22	0.07	enet	16	0.10	1.1e-03	18.94	17.7	4.6e-70	0.26	0.51	0.03	FALSE
1	CommonMind	Brain Pre-frontal Cortex	C6orf106	0.29	0.21	bslmm	382	0.23	6.9e-28	18.65	17.1	2.0e-65	-0.07	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	FANCE	0.03	0.02	bslmm	420	0.01	1.7e-02	-11.86	-16.2	6.5e-59	0.08	0.27	0.30	FALSE
43	GTEx	Skin Sun Exposed Lower leg	C6orf106	0.09	0.04	enet	25	0.02	4.6e-03	-8.16	16.0	9.5e-58	0.04	0.38	0.02	FALSE
38	GTEx	Pancreas	C6orf106	0.14	0.11	enet	11	0.13	2.8e-06	8.85	15.5	3.1e-54	0.10	0.86	0.01	FALSE
3	CommonMind	Brain Pre-frontal Cortex	PACSIN1	0.07	0.01	lasso	6	0.02	1.1e-03	18.95	15.1	3.2e-51	0.16	0.33	0.03	FALSE
78	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf106	0.03	0.03	lasso	3	0.01	7.6e-03	10.63	14.0	2.4e-44	0.00	0.01	0.91	FALSE
45	GTEx	Thyroid	C6orf106	0.09	0.01	enet	29	0.01	1.1e-01	18.96	13.6	4.3e-42	-0.10	0.10	0.04	FALSE
21	GTEx	Colon Transverse	C6orf106	0.15	0.05	lasso	1	0.03	1.5e-02	13.35	13.3	1.2e-40	-0.03	0.17	0.04	FALSE
87	The Cancer Genome Atlas	Prostate Adenocarcinoma	RPL10A	0.09	0.03	enet	19	0.07	1.1e-07	-10.15	-13.1	5.6e-39	0.01	0.94	0.02	FALSE
9	GTEx	Artery Tibial	C6orf106	0.07	0.02	lasso	4	0.02	8.8e-03	-10.12	12.9	4.3e-38	-0.13	0.10	0.05	FALSE
64	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	RPL10A	0.03	0.00	blup	54	0.02	6.0e-03	-12.78	-12.6	2.3e-36	0.03	0.01	0.85	FALSE
69	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C6orf106	0.09	0.03	lasso	5	0.05	3.6e-06	-8.03	12.5	6.9e-36	-0.03	0.31	0.06	FALSE
54	NTR	Blood	ZNF76	0.01	0.00	blup	424	0.00	3.8e-02	-8.69	12.3	5.0e-35	-0.17	0.24	0.02	FALSE
39	GTEx	Skin Not Sun Exposed Suprapubic	TEAD3	0.15	0.06	lasso	5	0.08	2.5e-05	-9.38	-11.6	6.3e-31	-0.09	0.38	0.52	FALSE
93	The Cancer Genome Atlas	Thyroid Carcinoma	RPL10A	0.05	0.07	enet	4	0.04	1.2e-04	-10.15	-11.4	4.6e-30	-0.03	0.76	0.05	FALSE
82	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	TCP11	0.03	0.03	blup	49	0.03	3.5e-04	-10.38	-11.3	9.6e-30	0.05	0.08	0.79	FALSE
96	The Cancer Genome Atlas	Thyroid Carcinoma	TCP11	0.03	0.02	blup	49	0.02	1.6e-03	-10.29	-11.3	1.5e-29	0.04	0.02	0.80	FALSE
22	GTEx	Colon Transverse	RPL10A	0.12	0.05	lasso	4	0.05	2.5e-03	-10.36	-11.0	2.2e-28	-0.06	0.25	0.13	FALSE
33	GTEx	Nerve Tibial	DEF6	0.15	0.00	lasso	8	0.00	1.6e-01	-10.05	11.0	2.3e-28	-0.01	0.18	0.05	FALSE
77	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ZNF76	0.08	0.05	lasso	10	0.07	4.9e-04	-13.36	-10.9	7.6e-28	0.06	0.05	0.35	FALSE
67	The Cancer Genome Atlas	Breast Invasive Carcinoma	TCP11	0.03	0.03	blup	49	0.04	6.6e-08	-6.26	-10.9	1.6e-27	0.07	0.73	0.27	FALSE
73	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TCP11	0.03	0.02	blup	49	0.02	1.7e-03	-6.00	-10.8	3.2e-27	0.07	0.02	0.94	FALSE
81	The Cancer Genome Atlas	Lung Adenocarcinoma	RPL10A	0.02	0.02	lasso	2	0.02	3.8e-03	-10.72	-10.7	7.8e-27	-0.01	0.08	0.04	FALSE
55	ROSMAP	Brain Pre-frontal Cortex	DEF6	0.04	0.02	bslmm	421	0.02	1.8e-03	-12.54	10.7	1.3e-26	-0.18	0.80	0.02	FALSE
70	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TCP11	0.03	0.00	blup	49	0.01	8.8e-03	-10.35	-10.5	7.5e-26	0.02	0.10	0.07	FALSE
8	GTEx	Artery Aorta	RPL10A	0.20	0.12	lasso	5	0.11	8.8e-07	-10.15	-10.5	1.4e-25	-0.04	0.96	0.00	FALSE
10	GTEx	Artery Tibial	RPL10A	0.11	0.08	lasso	2	0.09	1.5e-07	-10.36	-10.4	1.7e-25	-0.08	1.00	0.00	FALSE
85	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	TCP11	0.05	0.07	lasso	2	0.07	1.9e-05	-10.29	-10.4	3.4e-25	0.01	0.17	0.67	FALSE
49	METSIM	Adipose	C6orf106	0.04	0.02	blup	381	0.02	7.7e-04	10.63	10.4	3.7e-25	-0.13	0.43	0.02	FALSE
86	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	TCP11	0.08	0.11	lasso	2	0.11	3.4e-05	-10.29	-10.3	5.1e-25	0.01	0.13	0.53	FALSE
26	GTEx	Esophagus Muscularis	RPL10A	0.31	0.19	lasso	5	0.18	4.6e-11	-10.15	-10.3	9.0e-25	-0.01	1.00	0.00	FALSE
44	GTEx	Testis	ZNF76	0.15	0.14	enet	8	0.12	4.4e-06	-9.57	10.2	2.2e-24	-0.02	0.94	0.00	FALSE
31	GTEx	Muscle Skeletal	C6orf106	0.08	0.06	lasso	4	0.06	7.1e-07	8.94	-10.1	4.2e-24	-0.10	0.98	0.00	FALSE
76	The Cancer Genome Atlas	Brain Lower Grade Glioma	TCP11	0.05	0.04	blup	49	0.06	1.3e-07	-10.35	-10.1	7.9e-24	0.05	0.10	0.89	FALSE
17	GTEx	Cells EBV-transformed lymphocytes	C6orf106	0.20	0.00	lasso	5	0.00	2.7e-01	13.04	10.0	1.2e-23	0.08	0.07	0.05	FALSE
74	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PPARD	0.07	0.06	lasso	3	0.04	2.5e-03	-10.68	-10.0	1.3e-23	0.17	0.13	0.35	FALSE
68	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	TCP11	0.07	0.01	enet	8	0.01	8.2e-02	-10.65	-9.9	4.2e-23	-0.02	0.07	0.28	FALSE
57	ROSMAP	Brain Pre-frontal Cortex	ZNF76	0.04	0.00	blup	424	0.02	2.1e-03	-9.98	9.9	5.7e-23	-0.22	0.53	0.02	FALSE
63	YFS	Blood	ZNF76	0.05	0.08	lasso	4	0.07	6.7e-23	-10.04	9.8	7.7e-23	-0.17	1.00	0.00	FALSE
46	GTEx	Thyroid	RPL10A	0.16	0.09	lasso	11	0.07	8.9e-06	-9.24	-9.5	1.5e-21	-0.13	0.89	0.00	FALSE
90	The Cancer Genome Atlas	Prostate Adenocarcinoma	ZNF76	0.03	0.02	lasso	3	0.02	3.5e-03	-9.96	9.5	2.4e-21	-0.06	0.18	0.44	FALSE
35	GTEx	Nerve Tibial	RPL10A	0.14	0.12	lasso	3	0.12	9.7e-09	-10.15	-9.5	2.5e-21	-0.01	1.00	0.00	FALSE
48	GTEx	Whole Blood	DEF6	0.14	0.05	lasso	4	0.03	9.9e-04	-10.03	9.4	5.2e-21	-0.14	0.87	0.00	FALSE
14	GTEx	Brain Frontal Cortex BA9	TAF11	0.25	0.01	lasso	10	0.00	2.7e-01	-8.35	-9.3	8.6e-21	0.00	0.07	0.05	FALSE
50	METSIM	Adipose	RPL10A	0.18	0.13	lasso	15	0.13	3.4e-19	-10.15	-9.2	3.0e-20	0.00	1.00	0.00	FALSE
20	GTEx	Cells Transformed fibroblasts	NUDT3	0.11	0.03	lasso	3	0.02	9.2e-03	10.20	-9.2	3.8e-20	-0.40	0.24	0.03	FALSE
4	CommonMind	Brain Pre-frontal Cortex	RPL10A	0.21	0.09	enet	30	0.11	2.6e-13	-10.14	-9.2	5.2e-20	-0.01	1.00	0.00	FALSE
6	GTEx	Adipose Subcutaneous	RPL10A	0.06	0.02	enet	27	0.03	2.6e-03	-10.43	-9.2	5.5e-20	-0.10	0.32	0.04	FALSE
95	The Cancer Genome Atlas	Thyroid Carcinoma	TAF11	0.10	0.05	lasso	4	0.05	1.1e-05	-7.65	-8.8	1.0e-18	0.13	0.27	0.06	FALSE
32	GTEx	Muscle Skeletal	RPL10A	0.10	0.05	enet	17	0.04	3.9e-05	-10.14	-8.5	1.3e-17	-0.04	0.72	0.02	FALSE
18	GTEx	Cells Transformed fibroblasts	TEAD3	0.36	0.29	enet	27	0.32	8.4e-25	4.26	-8.5	1.7e-17	-0.09	1.00	0.00	FALSE
66	The Cancer Genome Atlas	Breast Invasive Carcinoma	RPL10A	0.03	0.00	blup	55	0.01	1.4e-03	-10.15	-8.4	3.4e-17	0.02	0.05	0.08	FALSE
56	ROSMAP	Brain Pre-frontal Cortex	TAF11	0.09	0.09	lasso	8	0.10	2.4e-12	-5.12	-8.4	6.1e-17	0.08	1.00	0.00	FALSE
94	The Cancer Genome Atlas	Thyroid Carcinoma	SCUBE3	0.03	0.01	blup	62	0.03	8.9e-04	-13.34	8.2	2.3e-16	-0.10	0.10	0.32	FALSE
62	YFS	Blood	RPL10A	0.24	0.11	lasso	11	0.13	4.4e-39	-10.15	-8.2	2.6e-16	-0.01	1.00	0.00	FALSE
47	GTEx	Uterus	UHRF1BP1	0.20	0.03	lasso	4	0.07	1.8e-02	2.28	8.2	2.7e-16	0.13	0.08	0.33	FALSE
29	GTEx	Lung	RPL10A	0.21	0.09	enet	53	0.09	1.2e-07	-10.15	-8.2	3.3e-16	-0.03	0.95	0.01	FALSE
40	GTEx	Skin Not Sun Exposed Suprapubic	SNRPC	0.18	0.04	enet	37	0.03	1.0e-02	2.32	8.1	4.1e-16	-0.04	0.25	0.03	FALSE
11	GTEx	Brain Cerebellum	PPARD	0.37	0.06	lasso	18	0.13	9.3e-05	1.08	-7.8	5.0e-15	0.05	0.14	0.04	FALSE
15	GTEx	Brain Frontal Cortex BA9	RPS10	0.21	0.08	lasso	3	0.06	8.6e-03	4.60	7.7	1.7e-14	-0.05	0.12	0.05	FALSE
60	ROSMAP	Brain Pre-frontal Cortex	RPL10A	0.30	0.18	bslmm	409	0.19	2.6e-24	-10.36	-7.5	7.1e-14	0.12	1.00	0.00	FALSE
51	METSIM	Adipose	SRPK1	0.06	0.01	blup	438	0.04	3.9e-07	1.07	-7.4	1.6e-13	-0.13	0.71	0.03	FALSE
88	The Cancer Genome Atlas	Prostate Adenocarcinoma	TAF11	0.11	0.04	enet	14	0.06	8.1e-07	-7.65	-7.4	1.9e-13	0.10	0.12	0.02	FALSE
65	The Cancer Genome Atlas	Breast Invasive Carcinoma	MAPK13	0.02	0.02	lasso	2	0.01	1.1e-03	6.53	6.7	2.4e-11	0.09	0.13	0.02	FALSE
25	GTEx	Esophagus Muscularis	MAPK13	0.13	0.09	enet	26	0.08	1.5e-05	3.59	6.5	7.9e-11	0.08	0.86	0.01	FALSE
41	GTEx	Skin Not Sun Exposed Suprapubic	MAPK13	0.20	0.05	lasso	5	0.08	2.8e-05	-3.52	6.5	9.1e-11	0.10	0.90	0.01	FALSE
7	GTEx	Artery Aorta	SNRPC	0.06	0.03	enet	14	0.02	1.8e-02	4.87	6.3	3.2e-10	-0.06	0.24	0.04	FALSE
27	GTEx	Esophagus Muscularis	NUDT3	0.12	0.00	lasso	7	0.02	3.2e-02	7.26	-6.2	4.0e-10	-0.13	0.14	0.08	FALSE
61	YFS	Blood	ANKS1A	0.04	0.00	bslmm	451	0.02	6.8e-07	-6.82	6.1	8.2e-10	0.12	0.82	0.00	FALSE
16	GTEx	Cells EBV-transformed lymphocytes	BRPF3	0.24	0.01	enet	26	0.00	4.2e-01	4.62	-6.1	9.3e-10	-0.11	0.07	0.06	FALSE
28	GTEx	Heart Atrial Appendage	TEAD3	0.17	0.08	lasso	6	0.09	1.1e-04	4.52	-5.8	6.5e-09	0.01	0.56	0.03	FALSE
79	The Cancer Genome Atlas	Lung Adenocarcinoma	C6orf126	0.03	0.00	enet	8	0.01	1.8e-02	4.00	5.6	1.7e-08	0.04	0.02	0.03	FALSE
37	GTEx	Pancreas	MAPK13	0.20	0.14	lasso	5	0.16	3.4e-07	4.62	5.5	3.2e-08	0.12	0.80	0.02	FALSE
52	METSIM	Adipose	TAF11	0.05	0.00	bslmm	359	0.01	2.7e-02	-8.74	-5.5	5.1e-08	0.04	0.11	0.04	FALSE
92	The Cancer Genome Atlas	Thyroid Carcinoma	MAPK13	0.07	0.06	lasso	6	0.06	1.5e-06	-3.57	5.3	1.0e-07	0.12	0.84	0.01	FALSE
30	GTEx	Muscle Skeletal	SNRPC	0.03	0.02	lasso	3	0.02	8.3e-03	2.25	-5.3	1.1e-07	-0.13	0.38	0.02	FALSE
23	GTEx	Esophagus Mucosa	MAPK13	0.34	0.29	lasso	5	0.38	2.3e-26	-3.52	5.2	1.5e-07	0.10	1.00	0.00	FALSE