Best TWAS P=2.29e-10 · Best GWAS P=7.63e-16 conditioned to 0.00019
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | LINC00461 | 0.10 | 0.07 | lasso | 2 | 0.05 | 4.5e-07 | 6.3 | 6.3 | 2.3e-10 | 0.41 | 0.99 | 0.01 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | 5.6 | 6.1 | 1.3e-09 | 0.39 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | LOC645323 | 0.05 | 0.01 | blup | 72 | 0.01 | 2.8e-02 | -4.8 | 6.1 | 1.2e-09 | 0.23 | 0.02 | 0.03 | FALSE |