Best TWAS P=1.17e-07 · Best GWAS P=1.32e-08 conditioned to 0.0328
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | ROSMAP | Brain Pre-frontal Cortex | CTD-3025N20.2 | 0.36 | 0.35 | lasso | 14 | 0.43 | 4.1e-61 | -5.4 | 5.3 | 1.2e-07 | -0.89 | 0.00 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | ARMC1 | 0.09 | 0.04 | blup | 41 | 0.08 | 4.5e-04 | -5.4 | -5.1 | 2.6e-07 | 0.87 | 0.02 | 0.84 | FALSE |