Best TWAS P=9.89e-11 · Best GWAS P=3.96e-07 conditioned to 0.000105
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pancreas | CPNE3 | 0.11 | 0.01 | enet | 22 | 0.00 | 5.7e-01 | -3.45 | 6.0 | 1.8e-09 | 0.24 | 0.15 | 0.17 | FALSE |
2 | GTEx | Spleen | RMDN1 | 0.46 | 0.20 | enet | 29 | 0.18 | 2.2e-05 | 4.74 | -5.4 | 6.5e-08 | -0.13 | 0.13 | 0.78 | FALSE |
3 | NTR | Blood | CPNE3 | 0.02 | 0.01 | blup | 451 | 0.01 | 2.1e-03 | -0.44 | 6.5 | 9.9e-11 | 0.20 | 0.25 | 0.05 | TRUE |