Best TWAS P=1.57e-09 · Best GWAS P=2.6e-07 conditioned to 0.847
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | IST1 | 0.09 | 0.05 | lasso | 4 | 0.08 | 4.2e-08 | 5.1 | -6.0 | 1.6e-09 | -0.84 | 0.03 | 0.97 | TRUE |
| 2 | GTEx | Nerve Tibial | PHLPP2 | 0.17 | 0.10 | enet | 21 | 0.13 | 2.5e-09 | -3.7 | -5.4 | 5.2e-08 | -0.68 | 0.25 | 0.71 | FALSE |
| 3 | GTEx | Testis | RP11-498D10.5 | 0.12 | 0.04 | enet | 6 | 0.01 | 1.1e-01 | 4.8 | -5.2 | 1.7e-07 | -0.95 | 0.04 | 0.72 | FALSE |