Best TWAS P=9.33e-11 · Best GWAS P=3.01e-11 conditioned to 0.0755
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RBL2 | 0.22 | 0.24 | enet | 15 | 0.26 | 1.8e-31 | 3.8 | -5.2 | 2.1e-07 | -0.87 | 0.75 | 0.25 | FALSE |
| 2 | GTEx | Muscle Skeletal | RBL2 | 0.11 | 0.00 | lasso | 5 | 0.00 | 2.9e-01 | 6.0 | -5.5 | 4.3e-08 | -0.87 | 0.01 | 0.97 | FALSE |
| 3 | YFS | Blood | AKTIP | 0.19 | 0.27 | lasso | 13 | 0.30 | 3.3e-99 | 6.6 | 5.8 | 8.5e-09 | 0.94 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Esophageal Carcinoma | RBL2 | 0.08 | 0.04 | lasso | 3 | 0.03 | 4.4e-02 | 6.6 | 6.0 | 2.2e-09 | 0.86 | 0.01 | 0.82 | FALSE |
| 5 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | RBL2 | 0.11 | 0.08 | blup | 44 | 0.06 | 1.5e-03 | 6.1 | -6.5 | 9.3e-11 | -0.92 | 0.01 | 0.79 | TRUE |