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chr20:2,390,880-3,850,968

Best TWAS P=1.09e-09 · Best GWAS P=5.54e-08 conditioned to 0.91

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	YFS	Blood	FASTKD5	0.02	0.01	lasso	6	0.01	2.2e-05	5.1	-6.1	1.1e-09	0.88	0.00	0.99	TRUE
1	GTEx	Artery Tibial	UBOX5	0.18	0.07	lasso	4	0.05	5.4e-05	-5.4	5.7	9.2e-09	-0.90	0.00	1.00	FALSE
5	GTEx	Heart Left Ventricle	UBOX5	0.20	0.09	enet	15	0.13	1.9e-07	4.3	5.7	1.3e-08	-0.79	0.01	0.98	FALSE
3	GTEx	Esophagus Mucosa	UBOX5	0.22	0.13	enet	10	0.18	6.8e-12	5.1	5.7	1.5e-08	-0.87	0.01	0.99	FALSE
7	GTEx	Nerve Tibial	UBOX5	0.14	0.05	lasso	5	0.08	4.2e-06	-5.4	5.5	2.9e-08	-0.90	0.00	1.00	FALSE
8	GTEx	Skin Sun Exposed Lower leg	LZTS3	0.20	0.03	enet	28	0.06	5.1e-06	3.9	-5.5	3.3e-08	0.60	0.06	0.92	FALSE
6	GTEx	Muscle Skeletal	UBOX5	0.12	0.09	enet	13	0.09	6.3e-09	5.1	5.5	4.3e-08	-0.81	0.01	0.98	FALSE
4	GTEx	Heart Atrial Appendage	UBOX5	0.32	0.07	enet	14	0.13	1.5e-06	4.9	5.5	4.6e-08	-0.77	0.02	0.97	FALSE
9	GTEx	Skin Sun Exposed Lower leg	UBOX5	0.08	0.04	lasso	3	0.05	6.9e-05	5.1	5.5	4.8e-08	-0.61	0.02	0.94	FALSE
10	GTEx	Thyroid	UBOX5	0.15	0.07	lasso	2	0.12	1.2e-09	5.1	5.4	7.3e-08	-0.87	0.01	0.99	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	UBOX5	0.35	0.22	lasso	4	0.23	5.7e-08	4.9	5.4	7.4e-08	-0.71	0.02	0.97	FALSE
11	ROSMAP	Brain Pre-frontal Cortex	UBOX5	0.26	0.17	lasso	8	0.16	4.1e-20	5.2	5.3	1.1e-07	-0.78	0.01	0.99	FALSE