Best TWAS P=4.56e-09 · Best GWAS P=2.24e-08 conditioned to 0.325
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | EDEM2 | 0.08 | 0.02 | lasso | 5 | 0.03 | 1.8e-03 | 3.9 | -5.8 | 5.0e-09 | -0.71 | 0.06 | 0.87 | FALSE |
| 2 | GTEx | Pancreas | MYH7B | 0.24 | 0.00 | enet | 17 | 0.04 | 1.0e-02 | 2.3 | 5.5 | 3.0e-08 | 0.76 | 0.03 | 0.58 | FALSE |
| 3 | METSIM | Adipose | PROCR | 0.04 | 0.00 | bslmm | 351 | 0.01 | 2.4e-02 | 2.7 | -5.3 | 1.0e-07 | -0.80 | 0.01 | 0.96 | FALSE |
| 4 | YFS | Blood | PROCR | 0.01 | 0.00 | blup | 348 | 0.01 | 3.3e-03 | 3.4 | -5.5 | 4.9e-08 | -0.77 | 0.02 | 0.91 | FALSE |
| 5 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PROCR | 0.18 | 0.00 | blup | 44 | 0.14 | 1.7e-05 | 5.6 | -5.9 | 4.6e-09 | -0.87 | 0.00 | 0.92 | TRUE |