TWAS
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chr10:102,853,189-104,242,886
Best TWAS P=2.63e-08 · Best GWAS P=9.98e-09 conditioned to 0.00146
102.8M
103M
103.2M
103.4M
103.6M
103.8M
104M
104.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
NPM3
0.03
0.01
lasso
2
0.03
1.2e-04
-5.5
5.6
2.6e-08
0.55
0.03
0.91
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
NPM3
0.02
0.03
lasso
3
0.02
9.2e-04
-5.2
5.5
3.0e-08
0.65
0.01
0.76
FALSE
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
C10orf76
0.19
0.20
lasso
1
0.18
4.6e-07
-5.2
-5.2
1.5e-07
-0.55
0.03
0.96
FALSE
2
GTEx
Testis
NPM3
0.13
0.15
lasso
3
0.13
2.5e-06
-5.2
5.2
1.8e-07
0.56
0.05
0.93
FALSE