Best TWAS P=2.63e-08 · Best GWAS P=9.98e-09 conditioned to 0.00146
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NPM3 | 0.03 | 0.01 | lasso | 2 | 0.03 | 1.2e-04 | -5.5 | 5.6 | 2.6e-08 | 0.55 | 0.03 | 0.91 | TRUE |
| 2 | GTEx | Testis | NPM3 | 0.13 | 0.15 | lasso | 3 | 0.13 | 2.5e-06 | -5.2 | 5.2 | 1.8e-07 | 0.56 | 0.05 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NPM3 | 0.02 | 0.03 | lasso | 3 | 0.02 | 9.2e-04 | -5.2 | 5.5 | 3.0e-08 | 0.65 | 0.01 | 0.76 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | C10orf76 | 0.19 | 0.20 | lasso | 1 | 0.18 | 4.6e-07 | -5.2 | -5.2 | 1.5e-07 | -0.55 | 0.03 | 0.96 | FALSE |