[Hub]/) : Traits : Qualifications: None of the above : ← →

chr10:64,195,778-65,911,294

Best TWAS P=3.43e-15 · Best GWAS P=1.63e-15 conditioned to 0.00112

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cortex	NRBF2	0.30	0.26	enet	24	0.21	1.4e-06	5.7	5.8	5.2e-09	-0.52	0.82	0.12	FALSE
2	GTEx	Brain Frontal Cortex BA9	NRBF2	0.25	0.17	lasso	6	0.16	6.1e-05	-6.8	6.6	3.1e-11	-0.55	0.53	0.08	FALSE
3	GTEx	Cells Transformed fibroblasts	JMJD1C	0.09	0.01	enet	18	0.07	8.6e-06	4.2	6.1	9.7e-10	-0.41	0.37	0.09	FALSE
4	GTEx	Esophagus Mucosa	NRBF2	0.14	0.11	lasso	10	0.11	6.4e-08	-6.3	6.2	8.0e-10	-0.54	0.57	0.42	FALSE
5	GTEx	Esophagus Muscularis	NRBF2	0.10	0.03	enet	22	0.03	3.8e-03	-6.1	5.5	2.8e-08	-0.45	0.28	0.30	FALSE
6	GTEx	Nerve Tibial	NRBF2	0.08	0.09	enet	11	0.06	5.0e-05	-6.3	6.1	1.2e-09	-0.49	0.96	0.02	FALSE
7	GTEx	Testis	NRBF2	0.14	0.08	lasso	12	0.09	6.7e-05	-6.3	6.0	1.5e-09	-0.52	0.78	0.03	FALSE
8	GTEx	Testis	JMJD1C-AS1	0.22	0.08	enet	23	0.10	3.7e-05	5.9	6.3	2.7e-10	-0.37	0.67	0.04	FALSE
9	GTEx	Thyroid	NRBF2	0.11	0.05	lasso	3	0.07	2.5e-06	4.6	5.9	3.1e-09	-0.53	0.63	0.21	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	NRBF2	0.34	0.46	lasso	5	0.46	3.1e-66	-6.8	6.7	2.3e-11	-0.55	0.98	0.02	FALSE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	NRBF2	0.07	0.04	blup	42	0.02	7.3e-03	-6.7	5.8	6.7e-09	-0.42	0.11	0.13	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	NRBF2	0.05	0.06	lasso	2	0.06	5.5e-12	-6.8	6.9	5.7e-12	-0.55	0.50	0.50	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	NRBF2	0.13	0.10	enet	11	0.09	4.9e-06	-6.8	5.8	6.5e-09	-0.49	0.22	0.48	FALSE
14	The Cancer Genome Atlas	Glioblastoma Multiforme	JMJD1C	0.11	0.02	blup	87	0.05	1.4e-02	-6.7	7.2	4.0e-13	-0.53	0.02	0.59	FALSE
15	The Cancer Genome Atlas	Glioblastoma Multiforme	NRBF2	0.17	0.09	enet	10	0.13	1.1e-04	-6.8	7.1	1.0e-12	-0.51	0.08	0.33	FALSE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NRBF2	0.04	0.04	enet	5	0.03	1.3e-04	-6.7	6.1	8.8e-10	-0.51	0.22	0.21	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	NRBF2	0.08	0.08	enet	6	0.08	4.3e-09	-6.8	6.8	1.0e-11	-0.57	0.49	0.50	FALSE
18	The Cancer Genome Atlas	Lung Adenocarcinoma	NRBF2	0.09	0.06	enet	8	0.07	2.7e-08	-6.7	5.9	3.7e-09	-0.50	0.50	0.48	FALSE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	NRBF2	0.09	0.02	enet	6	0.04	1.4e-05	1.8	5.1	2.9e-07	-0.50	0.40	0.36	FALSE
20	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC84989	0.10	0.05	blup	19	0.04	7.7e-03	5.9	7.1	1.2e-12	-0.44	0.01	0.38	FALSE
21	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	NRBF2	0.18	0.13	enet	11	0.08	2.5e-04	-6.7	7.9	3.4e-15	-0.73	0.04	0.90	TRUE
22	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	NRBF2	0.08	0.02	blup	40	0.04	8.6e-03	-6.8	6.3	2.3e-10	-0.43	0.03	0.07	FALSE
23	The Cancer Genome Atlas	Prostate Adenocarcinoma	NRBF2	0.08	0.09	lasso	6	0.08	9.7e-09	-6.7	6.4	1.6e-10	-0.52	0.50	0.50	FALSE
24	The Cancer Genome Atlas	Thyroid Carcinoma	NRBF2	0.14	0.10	enet	16	0.09	8.1e-09	-6.7	6.9	7.0e-12	-0.45	0.52	0.48	FALSE