Best TWAS P=8.3e-09 · Best GWAS P=5.07e-09 conditioned to 0.00315
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | GPD2 | 0.13 | 0.13 | enet | 12 | 0.14 | 1.1e-20 | 5.0 | 5.8 | 8.3e-09 | 0.61 | 0.11 | 0.89 | TRUE |
| 2 | NTR | Blood | GPD2 | 0.02 | 0.03 | lasso | 4 | 0.03 | 5.5e-09 | 5.2 | 5.2 | 1.8e-07 | 0.71 | 0.13 | 0.87 | FALSE |
| 3 | YFS | Blood | GPD2 | 0.05 | 0.06 | lasso | 7 | 0.06 | 1.4e-19 | 5.0 | 5.3 | 1.4e-07 | 0.71 | 0.11 | 0.89 | FALSE |