Best TWAS P=6.02e-10 · Best GWAS P=2.37e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CHST10 | 0.05 | 0.02 | blup | 474 | 0.04 | 1.0e-05 | -5.9 | 5.4 | 6.8e-08 | -0.77 | 0.16 | 0.84 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | CHST10 | 0.25 | 0.15 | lasso | 4 | 0.12 | 9.1e-05 | -6.3 | 6.1 | 1.2e-09 | -0.94 | 0.01 | 0.97 | FALSE |
| 3 | GTEx | Muscle Skeletal | LONRF2 | 0.07 | 0.08 | lasso | 4 | 0.08 | 2.5e-08 | 5.3 | 5.4 | 8.1e-08 | -0.81 | 0.33 | 0.67 | FALSE |
| 4 | GTEx | Skin Sun Exposed Lower leg | LONRF2 | 0.05 | 0.03 | lasso | 2 | 0.02 | 9.3e-03 | -5.8 | 5.8 | 6.1e-09 | -0.85 | 0.10 | 0.71 | FALSE |
| 5 | GTEx | Thyroid | CHST10 | 0.05 | 0.05 | lasso | 5 | 0.03 | 2.6e-03 | 5.2 | 5.6 | 1.7e-08 | -0.89 | 0.02 | 0.97 | FALSE |
| 6 | METSIM | Adipose | LONRF2 | 0.04 | 0.01 | bslmm | 445 | 0.02 | 1.9e-03 | 5.6 | 5.5 | 3.8e-08 | -0.71 | 0.12 | 0.82 | FALSE |
| 7 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LONRF2 | 0.06 | 0.04 | blup | 69 | 0.04 | 3.4e-05 | -5.6 | 6.2 | 6.0e-10 | -0.85 | 0.08 | 0.91 | FALSE |
| 8 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | LONRF2 | 0.05 | 0.08 | lasso | 2 | 0.08 | 2.9e-05 | -6.2 | 6.2 | 6.0e-10 | -0.98 | 0.00 | 0.98 | TRUE |
| 9 | The Cancer Genome Atlas | Thyroid Carcinoma | CHST10 | 0.04 | 0.04 | lasso | 3 | 0.03 | 2.6e-04 | 5.2 | 5.2 | 1.8e-07 | -0.80 | 0.03 | 0.95 | FALSE |