Best TWAS P=7.82e-08 · Best GWAS P=1.25e-09 conditioned to 0.000933
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | ST3GAL3 | 0.03 | -0.01 | lasso | 2 | 0.01 | 1.6e-01 | -5.4 | -5.4 | 7.8e-08 | 0.68 | 0.04 | 0.23 | TRUE |
| 2 | GTEx | Muscle Skeletal | B4GALT2 | 0.04 | 0.05 | lasso | 2 | 0.03 | 6.4e-04 | -5.2 | 5.2 | 1.7e-07 | -0.70 | 0.07 | 0.76 | FALSE |
| 3 | METSIM | Adipose | ARTN | 0.05 | 0.04 | bslmm | 412 | 0.03 | 1.3e-05 | -4.1 | -5.2 | 1.5e-07 | 0.82 | 0.06 | 0.94 | FALSE |