Best TWAS P=5.26e-16 · Best GWAS P=8.47e-18 conditioned to 0.00123
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CDKN2B | 0.08 | 0.05 | lasso | 4 | 0.06 | 2.4e-07 | 8.1 | 8.1 | 5.3e-16 | -0.85 | 0.03 | 0.97 | TRUE |
| 2 | CommonMind | Brain Pre-frontal Cortex | CDKN2B-AS1 | 0.11 | 0.02 | blup | 501 | 0.03 | 1.7e-04 | 8.1 | 5.5 | 4.4e-08 | -0.66 | 0.04 | 0.95 | FALSE |