TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Mouth/teeth dental problems: Mouth ulcers
:
→
chr1:150,008,790-151,547,253
Best TWAS P=7.58e-08 · Best GWAS P=2.59e-08 conditioned to 0.051
150M
150.2M
150.4M
150.6M
150.8M
151M
151.2M
151.4M
151.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
ENSA
0.02
0.01
enet
3
0.01
2.5e-02
5.3
-5.4
7.6e-08
-0.84
0.01
0.64
TRUE
3
GTEx
Thyroid
ARNT
0.08
0.10
lasso
10
0.10
7.8e-08
-4.9
5.3
9.4e-08
0.90
0.02
0.97
FALSE
1
GTEx
Adipose Subcutaneous
ARNT
0.06
0.01
lasso
3
0.00
3.9e-01
5.4
5.3
1.1e-07
0.66
0.03
0.86
FALSE
2
GTEx
Esophagus Muscularis
CTSS
0.05
0.04
enet
12
0.06
1.2e-04
4.7
5.2
2.0e-07
0.71
0.08
0.87
FALSE