Best TWAS P=7.58e-08 · Best GWAS P=2.59e-08 conditioned to 0.051
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | ARNT | 0.06 | 0.01 | lasso | 3 | 0.00 | 3.9e-01 | 5.4 | 5.3 | 1.1e-07 | 0.66 | 0.03 | 0.86 | FALSE |
2 | GTEx | Esophagus Muscularis | CTSS | 0.05 | 0.04 | enet | 12 | 0.06 | 1.2e-04 | 4.7 | 5.2 | 2.0e-07 | 0.71 | 0.08 | 0.87 | FALSE |
3 | GTEx | Thyroid | ARNT | 0.08 | 0.10 | lasso | 10 | 0.10 | 7.8e-08 | -4.9 | 5.3 | 9.4e-08 | 0.90 | 0.02 | 0.97 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ENSA | 0.02 | 0.01 | enet | 3 | 0.01 | 2.5e-02 | 5.3 | -5.4 | 7.6e-08 | -0.84 | 0.01 | 0.64 | TRUE |