468 significantly associated models · 55 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 150008790 | 151547253 | 3 | 1 | 7.6e-08 | 2.6e-08 | 5.1e-02 | 88 | ENSA |
2 | 1 | 160470756 | 161883083 | 1 | 1 | 2.0e-07 | 4.4e-07 | 1.0e+00 | 100 | NDUFS2 |
3 | 1 | 196798989 | 198436809 | 1 | 1 | 2.6e-09 | 1.7e-08 | 1.1e-02 | 80 | DENND1B |
4 | 3 | 45262393 | 47544003 | 10 | 6 | 1.6e-54 | 2.8e-52 | 1.0e+00 | 100 | CCR1 CCR3 CCR5 FYCO1 |
5 | 3 | 158296916 | 161490079 | 8 | 11 | 4.9e-19 | 7.1e-162 | NaN | NaN | IFT80 IL12A KPNA4 KRT8P12 PPM1L SCHIP1 TRIM59 |
6 | 5 | 158501850 | 159005439 | 1 | 1 | 2.5e-09 | 7.5e-10 | 6.3e-02 | 91 | IL12B |
7 | 7 | 127878155 | 129284182 | 1 | 1 | 3.9e-10 | 5.8e-09 | 7.5e-01 | 100 | IRF5 |
8 | 8 | 89923420 | 91465011 | 2 | 1 | 9.8e-08 | 1.5e-11 | 2.5e-06 | 51 | RIPK2 |
9 | 11 | 94861491 | 96256398 | 1 | 1 | 2.7e-07 | 6.1e-07 | 1.0e+00 | 100 | AP001877.1 |
10 | 16 | 85689653 | 86201589 | 1 | 1 | 5.1e-09 | 1.6e-13 | 1.3e-10 | 24 | IRF8 |
11 | 17 | 37820992 | 38316776 | 1 | 1 | 1.4e-07 | 1.5e-07 | 1.0e+00 | 100 | GSDMB |
12 | 17 | 42774693 | 45796313 | 19 | 1 | 1.6e-11 | 7.7e-11 | 1.0e+00 | 100 | KANSL1-AS1 |
13 | 19 | 4545717 | 5043573 | 1 | 1 | 9.8e-10 | 2.0e-10 | 1.0e+00 | 100 | FEM1A |
14 | 19 | 17473015 | 18902592 | 1 | 1 | 4.8e-12 | 1.1e-10 | 8.9e-01 | 100 | IL12RB1 |
15 | 19 | 46157004 | 47589895 | 3 | 1 | 6.2e-22 | 4.4e-20 | 1.1e-02 | 92 | AC007193.9 |
16 | 20 | 48109475 | 49505582 | 1 | 1 | 2.2e-07 | 5.7e-14 | 4.8e-08 | 47 | CEBPB |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Uterus | 6 | 1.058 | 2.0 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 4 | 0.579 | 2.0 |
GTEx | Brain Hippocampus | 5 | 0.954 | 1.9 |
GTEx | Brain Hypothalamus | 4 | 0.678 | 1.9 |
GTEx | Small Intestine Terminal Ileum | 4 | 0.868 | 1.9 |
GTEx | Artery Coronary | 9 | 0.761 | 1.8 |
GTEx | Brain Cortex | 9 | 0.870 | 1.8 |
GTEx | Brain Frontal Cortex BA9 | 6 | 0.649 | 1.8 |
GTEx | Brain Putamen basal ganglia | 5 | 0.801 | 1.8 |
GTEx | Breast Mammary Tissue (Male) | 7 | 0.587 | 1.8 |
GTEx | Liver | 5 | 0.697 | 1.8 |
GTEx | Ovary | 6 | 0.661 | 1.8 |
GTEx | Spleen | 7 | 0.496 | 1.8 |
GTEx | Whole Blood | 7 | 0.351 | 1.8 |
NTR | Blood | 7 | 0.291 | 1.8 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 5 | 0.489 | 1.8 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 4 | 0.787 | 1.8 |
GTEx | Adipose Visceral Omentum | 8 | 0.393 | 1.7 |
GTEx | Brain Nucleus accumbens basal ganglia | 6 | 0.694 | 1.7 |
GTEx | Breast Mammary Tissue | 7 | 0.355 | 1.7 |
GTEx | Breast Mammary Tissue (Female) | 6 | 0.365 | 1.7 |
GTEx | Cells EBV-transformed lymphocytes | 7 | 0.492 | 1.7 |
GTEx | Colon Sigmoid | 7 | 0.479 | 1.7 |
GTEx | Colon Transverse | 10 | 0.484 | 1.7 |
GTEx | Esophagus Gastroesophageal Junction | 8 | 0.554 | 1.7 |
GTEx | Heart Atrial Appendage | 7 | 0.443 | 1.7 |
GTEx | Pancreas | 7 | 0.429 | 1.7 |
GTEx | Pituitary | 4 | 0.359 | 1.7 |
GTEx | Prostate | 4 | 0.479 | 1.7 |
GTEx | Skin Not Sun Exposed Suprapubic | 8 | 0.325 | 1.7 |
GTEx | Vagina | 4 | 0.630 | 1.7 |
GTEx | Adipose Subcutaneous | 10 | 0.286 | 1.6 |
GTEx | Adrenal Gland | 5 | 0.343 | 1.6 |
GTEx | Artery Aorta | 10 | 0.336 | 1.6 |
GTEx | Brain Caudate basal ganglia | 4 | 0.435 | 1.6 |
GTEx | Brain Cerebellar Hemisphere | 6 | 0.403 | 1.6 |
GTEx | Brain Cerebellum | 6 | 0.303 | 1.6 |
GTEx | Cells Transformed fibroblasts | 10 | 0.238 | 1.6 |
GTEx | Esophagus Mucosa | 12 | 0.361 | 1.6 |
GTEx | Esophagus Muscularis | 13 | 0.402 | 1.6 |
GTEx | Heart Left Ventricle | 6 | 0.392 | 1.6 |
GTEx | Lung | 10 | 0.348 | 1.6 |
GTEx | Muscle Skeletal | 7 | 0.242 | 1.6 |
GTEx | Nerve Tibial | 9 | 0.208 | 1.6 |
GTEx | Stomach | 7 | 0.481 | 1.6 |
GTEx | Testis | 11 | 0.349 | 1.6 |
GTEx | Thyroid | 10 | 0.250 | 1.6 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 4 | 0.242 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 3 | 0.271 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 7 | 0.279 | 1.6 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 6 | 0.377 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 5 | 0.301 | 1.6 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 4 | 0.301 | 1.6 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.6 |
GTEx | Artery Tibial | 5 | 0.133 | 1.5 |
GTEx | Skin Sun Exposed Lower leg | 11 | 0.302 | 1.5 |
METSIM | Adipose | 7 | 0.152 | 1.5 |
YFS | Blood | 5 | 0.108 | 1.5 |
CommonMind | Brain Pre-frontal Cortex | 5 | 0.093 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 7 | 0.159 | 1.5 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.273 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 4 | 0.194 | 1.5 |
The Cancer Genome Atlas | Esophageal Carcinoma | 2 | 0.292 | 1.5 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 5 | 0.184 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 8 | 0.195 | 1.5 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 5 | 0.244 | 1.5 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 8 | 0.186 | 1.5 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 8 | 0.272 | 1.5 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 12 | 0.260 | 1.5 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 1 | 0.094 | 1.5 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 2 | 0.119 | 1.5 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 1 | 0.078 | 1.5 |
The Cancer Genome Atlas | Thyroid Carcinoma | 10 | 0.194 | 1.5 |
ROSMAP | Brain Pre-frontal Cortex | 0 | 0.000 | 1.4 |