[Hub]/) : Traits : Mouth/teeth dental problems: Mouth ulcers : ← →

chr7:127,878,155-129,284,182

Best TWAS P=3.85e-10 · Best GWAS P=5.75e-09 conditioned to 0.747

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
21	The Cancer Genome Atlas	Thyroid Carcinoma	IRF5	0.22	0.21	enet	9	0.26	4.6e-25	-5.8	6.3	3.9e-10	-0.95	0.00	1.00	TRUE
20	The Cancer Genome Atlas	Rectum Adenocarcinoma	IRF5	0.41	0.13	blup	33	0.23	3.5e-06	-5.8	6.1	1.2e-09	-0.91	0.00	0.99	FALSE
11	The Cancer Genome Atlas	Colon Adenocarcinoma	IRF5	0.29	0.26	enet	6	0.29	3.1e-17	-5.8	6.0	2.0e-09	-0.96	0.00	1.00	FALSE
12	The Cancer Genome Atlas	Glioblastoma Multiforme	IRF5	0.18	0.02	enet	8	0.04	2.4e-02	-4.2	6.0	2.2e-09	-0.67	0.01	0.63	FALSE
18	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	IRF5	0.09	0.10	lasso	3	0.08	4.6e-04	-5.8	5.8	5.6e-09	-1.00	0.00	0.96	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	IRF5	0.23	0.26	lasso	3	0.26	3.6e-27	-5.8	5.8	5.7e-09	-0.97	0.00	1.00	FALSE
1	GTEx	Adipose Visceral Omentum	IRF5	0.16	0.08	lasso	4	0.08	8.2e-05	5.4	5.7	1.2e-08	-0.87	0.01	0.98	FALSE
5	GTEx	Nerve Tibial	IRF5	0.13	0.09	enet	10	0.07	1.2e-05	5.4	5.7	1.4e-08	-0.90	0.01	0.99	FALSE
6	GTEx	Skin Sun Exposed Lower leg	IRF5	0.10	0.14	lasso	2	0.12	1.9e-10	5.4	5.6	1.8e-08	-0.87	0.00	0.99	FALSE
7	GTEx	Whole Blood	IRF5	0.17	0.06	lasso	4	0.09	1.2e-08	-4.8	5.6	1.9e-08	-0.90	0.02	0.98	FALSE
4	GTEx	Esophagus Muscularis	IRF5	0.21	0.12	lasso	5	0.11	3.9e-07	5.4	5.6	2.1e-08	-0.87	0.01	0.99	FALSE
15	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	IRF5	0.17	0.09	enet	6	0.15	1.8e-07	-3.9	5.6	2.4e-08	-0.84	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	IRF5	0.09	0.04	lasso	4	0.06	2.3e-04	5.4	5.5	2.9e-08	-0.91	0.00	0.99	FALSE
2	GTEx	Colon Transverse	IRF5	0.21	0.22	lasso	4	0.22	8.0e-11	5.4	5.5	3.5e-08	-0.86	0.01	0.99	FALSE
8	METSIM	Adipose	IRF5	0.05	0.04	lasso	7	0.04	2.2e-06	5.4	5.5	4.7e-08	-0.82	0.02	0.98	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	IRF5	0.18	0.11	enet	9	0.14	1.6e-15	5.4	5.5	5.0e-08	-0.86	0.00	1.00	FALSE
10	The Cancer Genome Atlas	Breast Invasive Carcinoma	IRF5	0.10	0.09	lasso	4	0.08	1.6e-16	5.4	5.4	7.7e-08	-0.84	0.01	0.99	FALSE
3	GTEx	Esophagus Mucosa	IRF5	0.13	0.14	lasso	4	0.13	4.6e-09	5.4	5.4	8.3e-08	-0.84	0.01	0.99	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	IRF5	0.14	0.15	enet	6	0.14	7.0e-10	-5.8	5.3	9.3e-08	-0.94	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	IRF5	0.11	0.05	blup	30	0.07	2.2e-08	5.4	5.3	1.2e-07	-0.84	0.00	1.00	FALSE
9	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	IRF5	0.09	0.06	blup	30	0.08	1.8e-07	-4.8	5.2	1.8e-07	-0.78	0.01	0.98	FALSE