[Hub]/) : Traits : Mouth/teeth dental problems: Mouth ulcers :

chr7:127,878,155-129,284,182

Best TWAS P=3.85e-10 · Best GWAS P=5.75e-09 conditioned to 0.747

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum IRF5 0.16 0.08 lasso 4 0.08 8.2e-05 5.4 5.7 1.2e-08 -0.87 0.01 0.98 FALSE
2 GTEx Colon Transverse IRF5 0.21 0.22 lasso 4 0.22 8.0e-11 5.4 5.5 3.5e-08 -0.86 0.01 0.99 FALSE
3 GTEx Esophagus Mucosa IRF5 0.13 0.14 lasso 4 0.13 4.6e-09 5.4 5.4 8.3e-08 -0.84 0.01 0.99 FALSE
4 GTEx Esophagus Muscularis IRF5 0.21 0.12 lasso 5 0.11 3.9e-07 5.4 5.6 2.1e-08 -0.87 0.01 0.99 FALSE
5 GTEx Nerve Tibial IRF5 0.13 0.09 enet 10 0.07 1.2e-05 5.4 5.7 1.4e-08 -0.90 0.01 0.99 FALSE
6 GTEx Skin Sun Exposed Lower leg IRF5 0.10 0.14 lasso 2 0.12 1.9e-10 5.4 5.6 1.8e-08 -0.87 0.00 0.99 FALSE
7 GTEx Whole Blood IRF5 0.17 0.06 lasso 4 0.09 1.2e-08 -4.8 5.6 1.9e-08 -0.90 0.02 0.98 FALSE
8 METSIM Adipose IRF5 0.05 0.04 lasso 7 0.04 2.2e-06 5.4 5.5 4.7e-08 -0.82 0.02 0.98 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma IRF5 0.09 0.06 blup 30 0.08 1.8e-07 -4.8 5.2 1.8e-07 -0.78 0.01 0.98 FALSE
10 The Cancer Genome Atlas Breast Invasive Carcinoma IRF5 0.10 0.09 lasso 4 0.08 1.6e-16 5.4 5.4 7.7e-08 -0.84 0.01 0.99 FALSE
11 The Cancer Genome Atlas Colon Adenocarcinoma IRF5 0.29 0.26 enet 6 0.29 3.1e-17 -5.8 6.0 2.0e-09 -0.96 0.00 1.00 FALSE
12 The Cancer Genome Atlas Glioblastoma Multiforme IRF5 0.18 0.02 enet 8 0.04 2.4e-02 -4.2 6.0 2.2e-09 -0.67 0.01 0.63 FALSE
13 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma IRF5 0.11 0.05 blup 30 0.07 2.2e-08 5.4 5.3 1.2e-07 -0.84 0.00 1.00 FALSE
14 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma IRF5 0.09 0.04 lasso 4 0.06 2.3e-04 5.4 5.5 2.9e-08 -0.91 0.00 0.99 FALSE
15 The Cancer Genome Atlas Liver Hepatocellular Carcinoma IRF5 0.17 0.09 enet 6 0.15 1.8e-07 -3.9 5.6 2.4e-08 -0.84 0.01 0.99 FALSE
16 The Cancer Genome Atlas Lung Adenocarcinoma IRF5 0.18 0.11 enet 9 0.14 1.6e-15 5.4 5.5 5.0e-08 -0.86 0.00 1.00 FALSE
17 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IRF5 0.14 0.15 enet 6 0.14 7.0e-10 -5.8 5.3 9.3e-08 -0.94 0.00 1.00 FALSE
18 The Cancer Genome Atlas Pancreatic Adenocarcinoma IRF5 0.09 0.10 lasso 3 0.08 4.6e-04 -5.8 5.8 5.6e-09 -1.00 0.00 0.96 FALSE
19 The Cancer Genome Atlas Prostate Adenocarcinoma IRF5 0.23 0.26 lasso 3 0.26 3.6e-27 -5.8 5.8 5.7e-09 -0.97 0.00 1.00 FALSE
20 The Cancer Genome Atlas Rectum Adenocarcinoma IRF5 0.41 0.13 blup 33 0.23 3.5e-06 -5.8 6.1 1.2e-09 -0.91 0.00 0.99 FALSE
21 The Cancer Genome Atlas Thyroid Carcinoma IRF5 0.22 0.21 enet 9 0.26 4.6e-25 -5.8 6.3 3.9e-10 -0.95 0.00 1.00 TRUE