Best TWAS P=9.83e-08 · Best GWAS P=1.48e-11 conditioned to 2.52e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | RP11-37B2.1 | 0.35 | 0.07 | enet | 25 | 0.12 | 1.7e-06 | 4.9 | -5.1 | 2.8e-07 | -0.46 | 0.33 | 0.41 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RIPK2 | 0.06 | 0.02 | blup | 49 | 0.05 | 2.4e-10 | -3.5 | 5.3 | 9.8e-08 | 0.50 | 0.98 | 0.01 | TRUE |
| 3 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | RIPK2 | 0.13 | 0.07 | enet | 4 | 0.14 | 1.3e-04 | -2.0 | 5.3 | 1.3e-07 | 0.73 | 0.02 | 0.79 | FALSE |