[Hub]/) : Traits : Mouth/teeth dental problems: Loose teeth :

chr12:27,587,038-29,432,481

Best TWAS P=2.39e-09 · Best GWAS P=9.14e-08 conditioned to 0.381

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Skin Not Sun Exposed Suprapubic	CCDC91	0.26	0.05	lasso	15	0.04	4.1e-03	5.2	6.0	2.4e-09	0.81	0.09	0.90	TRUE
1	GTEx	Artery Aorta	RP11-967K21.1	0.07	0.02	lasso	7	0.01	7.9e-02	-4.6	-5.8	5.3e-09	-0.84	0.09	0.73	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CCDC91	0.06	0.02	blup	174	0.04	2.9e-05	-4.7	5.7	1.4e-08	0.80	0.21	0.77	FALSE
4	GTEx	Colon Transverse	CCDC91	0.11	0.01	lasso	6	0.00	4.6e-01	5.0	5.6	2.2e-08	0.80	0.08	0.76	FALSE
2	GTEx	Artery Tibial	RP11-967K21.1	0.09	0.10	lasso	11	0.07	2.4e-06	-5.1	-5.5	3.6e-08	-0.58	0.16	0.84	FALSE
6	GTEx	Esophagus Muscularis	RP11-967K21.1	0.07	0.06	lasso	5	0.04	2.2e-03	-5.0	-5.5	4.8e-08	-0.55	0.15	0.57	FALSE
3	GTEx	Cells Transformed fibroblasts	RP11-967K21.1	0.07	0.07	lasso	2	0.07	3.7e-06	5.2	-5.4	7.2e-08	-0.97	0.06	0.94	FALSE
10	NTR	Blood	CCDC91	0.01	0.01	blup	648	0.00	9.0e-03	-4.9	5.4	8.1e-08	0.76	0.15	0.66	FALSE
9	GTEx	Skin Sun Exposed Lower leg	CCDC91	0.09	0.01	enet	8	0.01	2.6e-02	5.2	5.3	9.4e-08	0.91	0.10	0.84	FALSE
7	GTEx	Heart Atrial Appendage	RP11-967K21.1	0.08	0.09	lasso	1	0.08	2.3e-04	5.2	-5.2	1.9e-07	-0.96	0.06	0.87	FALSE
5	GTEx	Colon Transverse	RP11-967K21.1	0.12	0.07	lasso	8	0.05	1.6e-03	-5.1	-5.2	2.3e-07	-0.56	0.15	0.77	FALSE