[Hub]/) : Traits : Mouth/teeth dental problems: Loose teeth :

chr12:27,587,038-29,432,481

Best TWAS P=2.39e-09 · Best GWAS P=9.14e-08 conditioned to 0.381

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta RP11-967K21.1 0.07 0.02 lasso 7 0.01 7.9e-02 -4.6 -5.8 5.3e-09 -0.84 0.09 0.73 FALSE
2 GTEx Artery Tibial RP11-967K21.1 0.09 0.10 lasso 11 0.07 2.4e-06 -5.1 -5.5 3.6e-08 -0.58 0.16 0.84 FALSE
3 GTEx Cells Transformed fibroblasts RP11-967K21.1 0.07 0.07 lasso 2 0.07 3.7e-06 5.2 -5.4 7.2e-08 -0.97 0.06 0.94 FALSE
4 GTEx Colon Transverse CCDC91 0.11 0.01 lasso 6 0.00 4.6e-01 5.0 5.6 2.2e-08 0.80 0.08 0.76 FALSE
5 GTEx Colon Transverse RP11-967K21.1 0.12 0.07 lasso 8 0.05 1.6e-03 -5.1 -5.2 2.3e-07 -0.56 0.15 0.77 FALSE
6 GTEx Esophagus Muscularis RP11-967K21.1 0.07 0.06 lasso 5 0.04 2.2e-03 -5.0 -5.5 4.8e-08 -0.55 0.15 0.57 FALSE
7 GTEx Heart Atrial Appendage RP11-967K21.1 0.08 0.09 lasso 1 0.08 2.3e-04 5.2 -5.2 1.9e-07 -0.96 0.06 0.87 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic CCDC91 0.26 0.05 lasso 15 0.04 4.1e-03 5.2 6.0 2.4e-09 0.81 0.09 0.90 TRUE
9 GTEx Skin Sun Exposed Lower leg CCDC91 0.09 0.01 enet 8 0.01 2.6e-02 5.2 5.3 9.4e-08 0.91 0.10 0.84 FALSE
10 NTR Blood CCDC91 0.01 0.01 blup 648 0.00 9.0e-03 -4.9 5.4 8.1e-08 0.76 0.15 0.66 FALSE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CCDC91 0.06 0.02 blup 174 0.04 2.9e-05 -4.7 5.7 1.4e-08 0.80 0.21 0.77 FALSE