Best TWAS P=3.63e-14 · Best GWAS P=1.07e-23 conditioned to 7.51e-12
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | U91328.19 | 0.28 | 0.12 | lasso | 10 | 0.14 | 1.3e-05 | -4.5 | 5.2 | 2.1e-07 | -0.34 | 0.95 | 0.00 | FALSE |
| 2 | GTEx | Brain Cerebellar Hemisphere | U91328.19 | 0.47 | 0.33 | enet | 44 | 0.26 | 2.8e-07 | -4.5 | 6.2 | 5.8e-10 | -0.37 | 0.98 | 0.00 | FALSE |
| 3 | GTEx | Brain Frontal Cortex BA9 | U91328.19 | 0.17 | 0.16 | lasso | 4 | 0.18 | 1.8e-05 | -4.9 | 5.2 | 2.5e-07 | -0.32 | 0.45 | 0.04 | FALSE |
| 4 | GTEx | Liver | U91328.19 | 0.16 | 0.14 | lasso | 2 | 0.05 | 1.9e-02 | -6.3 | 6.3 | 2.5e-10 | -0.39 | 0.25 | 0.18 | TRUE |
| 5 | GTEx | Ovary | U91328.19 | 0.37 | 0.17 | enet | 18 | 0.34 | 4.7e-09 | -4.9 | 7.6 | 3.6e-14 | -0.41 | 0.75 | 0.03 | TRUE |
| 6 | METSIM | Adipose | U91328.19 | 0.19 | 0.24 | lasso | 23 | 0.25 | 1.7e-36 | -4.5 | 5.1 | 2.9e-07 | -0.31 | 1.00 | 0.00 | TRUE |