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Traits
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Mouth/teeth dental problems: Dentures
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chr6:25,296,606-26,689,223
Best TWAS P=3.63e-14 · Best GWAS P=1.07e-23 conditioned to 7.51e-12
25.4M
25.6M
25.8M
26M
26.2M
26.4M
26.6M
0
5
10
15
20
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
GTEx
Ovary
U91328.19
0.37
0.17
enet
18
0.34
4.7e-09
-4.9
7.6
3.6e-14
-0.41
0.75
0.03
TRUE
4
GTEx
Liver
U91328.19
0.16
0.14
lasso
2
0.05
1.9e-02
-6.3
6.3
2.5e-10
-0.39
0.25
0.18
TRUE
6
METSIM
Adipose
U91328.19
0.19
0.24
lasso
23
0.25
1.7e-36
-4.5
5.1
2.9e-07
-0.31
1.00
0.00
TRUE
2
GTEx
Brain Cerebellar Hemisphere
U91328.19
0.47
0.33
enet
44
0.26
2.8e-07
-4.5
6.2
5.8e-10
-0.37
0.98
0.00
FALSE
1
GTEx
Adrenal Gland
U91328.19
0.28
0.12
lasso
10
0.14
1.3e-05
-4.5
5.2
2.1e-07
-0.34
0.95
0.00
FALSE
3
GTEx
Brain Frontal Cortex BA9
U91328.19
0.17
0.16
lasso
4
0.18
1.8e-05
-4.9
5.2
2.5e-07
-0.32
0.45
0.04
FALSE