Best TWAS P=5.08e-09 · Best GWAS P=8.92e-12 conditioned to 3.94e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | SLC22A3 | 0.10 | 0.02 | blup | 582 | 0.05 | 4.4e-07 | 1.9 | 5.8 | 5.1e-09 | 0.09 | 0.75 | 0.23 | TRUE |
| 2 | GTEx | Artery Tibial | RP11-288H12.3 | 0.17 | 0.01 | lasso | 8 | 0.06 | 2.3e-05 | 4.3 | 5.7 | 1.2e-08 | 0.14 | 0.22 | 0.07 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SLC22A1 | 0.04 | 0.01 | enet | 17 | 0.01 | 5.2e-04 | 4.8 | -5.3 | 9.6e-08 | -0.59 | 0.01 | 0.94 | TRUE |