TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Vascular/heart problems diagnosed by doctor
:
→
chr1:752,566-2,061,969
Best TWAS P=2.4e-07 · Best GWAS P=4.99e-06 conditioned to 0.00512
0.8M
1M
1.2M
1.4M
1.6M
1.8M
2M
0
1
2
3
4
5
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Brain Caudate basal ganglia
RP4-758J18.10
0.2
-0.01
lasso
5
0.03
0.056
-3.8
5.2
2.4e-07
-0.38
0.01
0.02
TRUE