Hub : Traits :

Vascular/heart problems diagnosed by doctor

1231 significantly associated models · 331 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	752566	2061969	1	1	2.4e-07	5.0e-06	5.1e-03	62	RP4-758J18.10
2	1	7715776	9571422	2	1	1.9e-08	4.3e-08	2.5e-01	96	RP5-1115A15.1
3	1	11060075	12600396	5	2	5.5e-25	5.4e-26	4.4e-05	85	CLCN6
4	1	20373107	21742737	1	1	2.8e-07	1.8e-07	3.9e-02	84	RP5-930J4.4
5	1	26428864	28406173	5	2	5.9e-10	3.7e-08	6.8e-01	99	FCN3 PIGV
6	1	42542658	43978837	3	1	5.4e-08	6.2e-08	8.5e-02	90	RP5-994D16.9
7	1	88621347	90134392	2	1	2.8e-12	5.7e-12	9.0e-02	94	GTF2B
8	1	112312154	113941737	5	2	2.9e-15	4.1e-17	7.9e-08	59	CAPZA1 RHOC
9	1	115486678	116932921	1	1	2.3e-07	1.3e-12	5.9e-11	15	VANGL1
10	1	227217340	228663659	1	1	5.1e-08	3.4e-09	9.0e-05	56	SNAP47
11	1	230142626	231548480	1	1	2.5e-12	7.1e-11	5.4e-02	91	AGT
12	2	24021231	26068509	3	2	1.4e-08	1.2e-06	5.0e-01	98	ADCY3 EFR3B
13	2	36778887	38245716	1	1	4.5e-09	3.8e-08	1.0e+00	100	PRKD3
14	2	158621356	160236990	1	1	3.1e-07	2.6e-08	6.6e-04	62	PKP4
15	2	181042370	184084221	3	2	3.4e-09	1.4e-09	1.1e-02	82	PDE1A UBE2E3
16	2	218622292	220128895	1	1	1.9e-07	1.9e-04	1.4e-01	84	USP37
17	3	10617048	12239931	1	1	9.2e-08	1.3e-09	3.9e-03	77	ATG7
18	3	26563909	28211713	2	1	3.0e-16	1.6e-17	1.1e-02	91	SLC4A7
19	3	38812165	40267321	1	1	2.5e-07	1.0e-05	2.9e-03	54	MOBP
20	3	47204518	49365269	8	1	9.5e-12	7.9e-12	1.0e+00	100	FCF1P2
21	3	133088362	134666475	1	1	4.7e-08	5.4e-09	8.4e-03	80	RYK
22	3	135273949	136746974	1	1	1.5e-07	1.4e-09	1.7e-03	73	PCCB
23	3	137189600	139050702	5	1	1.7e-11	1.2e-11	1.5e-01	96	DBR1
24	3	157125828	158980014	2	1	1.7e-07	1.8e-06	3.4e-01	96	RP11-538P18.2
25	4	17104059	18507692	2	1	1.6e-09	7.5e-10	6.1e-03	80	DCAF16
26	4	25880334	27452482	1	2	1.2e-10	1.1e-14	5.1e-09	43	TBC1D19
27	4	37915462	39361551	1	1	2.2e-07	4.2e-08	1.3e-06	22	RP11-617D20.1
28	4	80488345	82578407	2	1	7.9e-18	2.5e-58	1.8e-42	28	C4orf22
29	4	102868793	104627833	5	1	6.4e-12	1.2e-10	9.3e-01	100	CISD2
30	4	155890241	157354250	2	1	2.4e-09	1.1e-13	6.7e-13	7	RP11-588K22.2
31	5	130830617	132425049	8	1	1.2e-09	2.3e-09	4.5e-03	77	P4HA2-AS1
32	5	147516165	148894875	1	1	1.9e-07	2.9e-10	9.5e-07	40	ADRB2
33	6	42586058	44034691	2	1	1.9e-12	8.7e-13	1.0e+00	100	ZNF318
34	6	57608708	58770624	1	1	1.8e-07	5.3e-07	8.7e-03	73	LINC00680
35	6	78880271	80486611	2	1	3.3e-09	1.2e-08	3.1e-01	97	PHIP
36	6	117078784	118613435	2	2	6.9e-08	1.3e-08	1.2e-08	0	DCBLD1 GOPC
37	6	133961374	134468561	1	1	6.9e-09	5.8e-11	1.8e-03	77	TCF21
38	7	1787236	3264728	2	1	6.7e-11	1.5e-10	1.0e+00	100	LFNG
39	7	6502367	7988091	1	1	2.0e-14	7.8e-11	7.6e-02	93	C1GALT1
40	7	26969253	27533292	2	1	2.5e-12	4.1e-14	2.3e-03	84	HOXA10
41	7	73425238	75255633	5	1	8.2e-09	1.6e-08	4.3e-02	87	STAG3L2
42	7	129342404	130779678	2	2	7.1e-11	5.6e-14	2.2e-05	68	CEP41 ZC3HC1
43	8	8092025	13120332	19	2	1.1e-13	1.5e-13	1.8e-03	82	MSRA NEIL2
44	8	29996824	31433801	1	1	5.7e-09	9.8e-10	6.2e-02	91	TEX15
45	8	82017372	83452091	1	1	3.8e-08	4.8e-09	1.6e-02	83	SNX16
46	8	95213858	96825195	3	1	5.3e-09	2.7e-08	1.9e-01	94	NDUFAF6
47	8	102002608	103832256	2	1	3.5e-09	1.3e-09	6.6e-04	68	KB-1107E3.1
48	10	18221643	19601824	2	2	6.8e-11	1.9e-17	3.8e-15	14	CACNB2 NSUN6
49	10	62473976	65606229	4	2	5.4e-12	6.4e-28	7.5e-26	8	NRBF2 TMEM26
50	10	95379543	96818402	1	1	2.6e-08	1.5e-10	5.8e-07	39	NOC3L
51	10	103313599	105850787	8	1	2.1e-15	1.2e-16	4.1e-03	88	NT5C2
52	10	115244596	116689519	3	3	1.9e-12	1.9e-19	2.6e-08	62	ADRB1 C10orf118 TDRD1
53	11	1213806	2705175	5	2	3.6e-18	3.8e-20	7.1e-03	91	LSP1 TNNT3
54	11	9003306	10471931	1	1	6.2e-10	2.9e-12	2.3e-04	72	SWAP70
55	11	15741673	17001235	1	1	6.3e-09	1.3e-15	2.0e-09	44	SOX6
56	11	42881882	44596817	2	1	1.6e-08	9.2e-10	2.9e-03	76	HSD17B12
57	11	46010847	48783497	19	1	5.4e-21	1.8e-18	7.1e-07	68	ACP2
58	11	64721908	66333072	3	1	5.7e-12	3.8e-12	6.9e-06	58	RNASEH2C
59	11	99859184	101559718	2	1	4.6e-36	1.4e-34	1.4e-01	98	TMEM133
60	11	106485489	108027561	2	1	2.4e-10	2.0e-11	5.9e-03	83	CWF19L2
61	11	110721187	112491227	5	1	1.3e-10	1.3e-10	1.0e+00	100	SIK2
62	12	47407397	49195124	3	2	1.4e-07	1.1e-07	1.2e-04	47	RP1-197B17.3 SENP1
63	12	49827409	51256065	2	1	5.8e-08	3.0e-10	2.2e-08	21	CERS5
64	12	54158993	54760824	4	1	3.5e-09	1.6e-09	2.8e-02	87	FLJ12825
65	12	69057879	70476863	1	1	4.7e-10	3.4e-09	2.7e-01	96	YEATS4
66	12	89116708	90799212	3	1	3.2e-13	2.9e-22	4.8e-14	40	ATP2B1
67	12	109591369	111015121	2	1	8.0e-08	1.3e-06	2.3e-01	94	TCHP
68	12	111102574	113517494	15	2	1.5e-21	7.2e-33	2.3e-08	78	ADAM1A SH2B3
69	12	121146219	123131824	3	3	6.8e-15	1.3e-14	1.0e+00	100	KDM2B RNF34 WDR66
70	14	103349176	104866687	4	1	1.1e-07	2.0e-07	1.0e+00	100	C14orf153
71	15	40360741	42749023	8	1	5.4e-12	8.9e-12	1.7e-01	96	CHP1
72	15	67138238	68789191	1	1	1.0e-08	1.2e-08	2.4e-01	96	MAP2K5
73	15	73933444	76108550	14	10	3.7e-22	5.4e-22	1.0e+00	100	ARID3B COX5A CSK MPI RPP25 UBL7 ULK3
74	15	80377452	81936479	2	1	4.1e-11	7.8e-14	2.9e-04	76	FAM108C1
75	15	90712555	92187978	3	3	7.8e-43	3.7e-32	6.3e-01	100	FES FURIN
76	16	3025993	5441125	4	3	3.0e-11	1.1e-08	1.3e-05	42	AC006111.1 MGRN1
77	16	24614505	25167985	1	1	3.9e-08	2.0e-07	1.0e+00	100	SLC5A11
78	16	29711343	31833122	12	2	1.2e-10	8.9e-11	1.0e+00	100	FAM57B VKORC1
79	16	81230341	81993974	1	1	3.4e-14	8.3e-13	1.1e-02	88	CMIP
80	16	89013848	90172696	8	1	9.3e-12	1.2e-11	8.7e-02	94	CHMP1A
81	17	3371501	4766937	1	1	9.3e-08	3.7e-07	4.6e-01	98	RP11-810M2.2
82	17	6754828	8484683	8	3	2.7e-09	3.4e-09	1.0e+00	100	CYB5D1 SENP3 SLC2A4
83	17	42976114	43383100	1	1	3.1e-08	9.4e-07	3.2e-01	96	HEXIM1
84	17	46258510	48139500	7	8	1.2e-15	1.8e-17	NaN	NaN	AC091133.1 RP11-463M16.4 SNF8 UBE2Z ZNF652
85	17	60858059	62279811	2	1	4.8e-15	4.8e-15	1.0e+00	100	ACE
86	17	73220999	74629867	1	1	3.1e-07	3.0e-07	1.9e-01	93	FBF1
87	17	78665405	80023050	1	1	1.2e-07	1.7e-05	3.9e-04	32	RP11-1055B8.4
88	19	1163934	2560423	3	2	6.2e-08	2.0e-08	1.0e+00	100	CTB-31O20.6 KLF16
89	19	7793502	9200017	1	1	1.9e-07	1.3e-06	6.8e-01	99	MARCH2
90	19	16462417	18180451	4	2	5.9e-13	3.1e-14	1.0e+00	100	CTD-3032J10.3 MYO9B
91	19	48918157	49452462	2	1	3.3e-08	1.7e-07	4.5e-01	98	NTN5
92	20	7419920	9648826	1	2	3.7e-11	2.5e-18	6.3e-07	67	PLCB1
93	20	29927166	31615615	3	2	3.4e-09	1.1e-09	1.9e-07	27	C20orf160 TSPY26P
94	20	56858751	58262841	3	3	8.1e-20	1.4e-34	2.5e-10	73	NELFCD TH1L ZNF831
95	20	61522825	62912463	8	6	5.7e-14	2.2e-12	1.0e+00	100	GMEB2 OPRL1 RGS19 TCEA2 ZBTB46
96	21	44251223	45879403	3	1	1.6e-09	2.4e-10	2.1e-02	87	PDXK
97	22	29033458	29702654	1	1	1.8e-10	1.7e-06	2.6e-01	94	ZNRF3

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
High blood pressure	15.02	137	114	253.3	-1.00	3.8e-166	AC006111.1 AC091133.1 ACE ACP2 ADAM1A ADCY3 ADRB1 ADRB2 AGT ARID3B ATG7 ATP2B1 C10orf118 C14orf153 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTD-3032J10.3 CWF19L2 CYB5D1 DBR1 DCAF16 DCBLD1 EFR3B FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 HSD17B12 KB-1107E3.1 KDM2B KLF16 LFNG LINC00680 LSP1 MAP2K5 MARCH2 MGRN1 MOBP MPI MSRA MYO9B NDUFAF6 NEIL2 NELFCD NOC3L NRBF2 NSUN6 NT5C2 NTN5 OPRL1 P4HA2-AS1 PCCB PDE1A PDXK PHIP PIGV PKP4 PLCB1 PRKD3 RGS19 RHOC RNASEH2C RNF34 RP11-1055B8.4 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP1-197B17.3 RP4-758J18.10 RP5-1115A15.1 RP5-930J4.4 RP5-994D16.9 RPP25 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SLC5A11 SNAP47 SNF8 SNX16 SOX6 STAG3L2 SWAP70 TBC1D19 TCEA2 TCF21 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM26 TNNT3 TSPY26P UBE2E3 UBE2Z UBL7 ULK3 USP37 VANGL1 VKORC1 WDR66 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Hypertension (Self-reported)	14.82	137	115	255.6	-1.00	3.1e-157	AC006111.1 AC091133.1 ACE ACP2 ADAM1A ADCY3 ADRB1 ADRB2 AGT ARID3B ATG7 ATP2B1 C10orf118 C14orf153 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTD-3032J10.3 CWF19L2 CYB5D1 DBR1 DCAF16 DCBLD1 EFR3B FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 HSD17B12 KB-1107E3.1 KDM2B KLF16 LFNG LINC00680 LSP1 MAP2K5 MARCH2 MGRN1 MOBP MPI MSRA MYO9B NDUFAF6 NEIL2 NELFCD NOC3L NRBF2 NSUN6 NT5C2 NTN5 OPRL1 P4HA2-AS1 PCCB PDE1A PDXK PHIP PIGV PKP4 PLCB1 PRKD3 RGS19 RHOC RNASEH2C RNF34 RP11-1055B8.4 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP1-197B17.3 RP4-758J18.10 RP5-1115A15.1 RP5-930J4.4 RP5-994D16.9 RPP25 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SLC5A11 SNAP47 SNF8 SNX16 SOX6 STAG3L2 SWAP70 TBC1D19 TCEA2 TCF21 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM26 TNNT3 TSPY26P UBE2E3 UBE2Z UBL7 ULK3 USP37 VANGL1 VKORC1 WDR66 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Cardiovascular Disease	13.88	129	105	233.3	-0.99	7.2e-122	AC006111.1 AC091133.1 ACE ACP2 ADAM1A ADCY3 ADRB1 ADRB2 AGT ARID3B ATG7 ATP2B1 C10orf118 C14orf153 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTD-3032J10.3 CWF19L2 CYB5D1 DBR1 DCAF16 DCBLD1 EFR3B FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 HSD17B12 KB-1107E3.1 KDM2B KLF16 LFNG LSP1 MAP2K5 MARCH2 MGRN1 MOBP MPI MYO9B NDUFAF6 NELFCD NOC3L NRBF2 NSUN6 NT5C2 NTN5 OPRL1 P4HA2-AS1 PCCB PDE1A PDXK PHIP PIGV PLCB1 RGS19 RHOC RNASEH2C RNF34 RP11-1055B8.4 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-758J18.10 RP5-1115A15.1 RP5-930J4.4 RP5-994D16.9 RPP25 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SNAP47 SNF8 SNX16 SOX6 STAG3L2 SWAP70 TBC1D19 TCEA2 TCF21 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM26 TNNT3 TSPY26P UBE2Z UBL7 ULK3 USP37 VANGL1 VKORC1 WDR66 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Systolic Blood Pressure	12.85	111	93	206.7	-0.96	1.0e-68	AC006111.1 AC091133.1 ACE ACP2 ADAM1A ADRB1 ADRB2 AGT ARID3B ATG7 ATP2B1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CERS5 CHMP1A CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTD-3032J10.3 CWF19L2 CYB5D1 DBR1 DCAF16 DCBLD1 EFR3B FAM108C1 FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 KB-1107E3.1 KDM2B KLF16 LFNG LSP1 MGRN1 MPI MYO9B NDUFAF6 NEIL2 NELFCD NOC3L NRBF2 NSUN6 NT5C2 NTN5 OPRL1 PDE1A PDXK PHIP PIGV PLCB1 PRKD3 RGS19 RHOC RNASEH2C RNF34 RP11-1055B8.4 RP11-463M16.4 RP11-538P18.2 RP11-588K22.2 RP4-758J18.10 RP5-1115A15.1 RP5-930J4.4 RPP25 RYK SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SLC5A11 SNAP47 SNF8 SNX16 SOX6 STAG3L2 SWAP70 TBC1D19 TCEA2 TCF21 TCHP TH1L TMEM133 TMEM26 TNNT3 UBE2Z UBL7 ULK3 WDR66 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831 ZNRF3
Medication: Blood pressure	11.21	78	35	77.8	-0.99	2.0e-67	ACE ACP2 ADCY3 ADRB1 ADRB2 AGT ARID3B ATG7 ATP2B1 C1GALT1 C4orf22 CACNB2 CAPZA1 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTD-3032J10.3 CWF19L2 CYB5D1 DBR1 FAM108C1 FCF1P2 FES FLJ12825 FURIN GMEB2 GTF2B HEXIM1 HOXA10 KB-1107E3.1 KDM2B LFNG LSP1 MGRN1 MPI MSRA MYO9B NEIL2 NRBF2 NSUN6 NT5C2 NTN5 OPRL1 P4HA2-AS1 PCCB PDXK PIGV PLCB1 PRKD3 RGS19 RHOC RNASEH2C RNF34 RP11-1055B8.4 RP11-588K22.2 RP11-810M2.2 RPP25 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 TBC1D19 TCEA2 TDRD1 TEX15 TMEM133 TNNT3 UBL7 ZBTB46 ZNF318 ZNF831 ZNRF3
Medication: Blood pressure	10.39	56	26	57.8	-0.99	7.5e-53	AC091133.1 ACE ACP2 ADAM1A ADRB1 ATP2B1 C1GALT1 C20orf160 C4orf22 CAPZA1 CEP41 CHMP1A CISD2 CLCN6 CMIP CSK CWF19L2 CYB5D1 DCAF16 EFR3B FAM108C1 FAM57B FCF1P2 FES FURIN HOXA10 KDM2B KLF16 LFNG LSP1 MOBP NOC3L PDXK PLCB1 RHOC RNF34 RP11-463M16.4 RP11-810M2.2 SENP1 SENP3 SH2B3 SIK2 SLC2A4 SLC4A7 SOX6 TCF21 TMEM133 TNNT3 TSPY26P ULK3 WDR66 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831
Systolic blood pressure, automated reading	9.69	76	51	113.3	-0.98	1.2e-54	AC006111.1 ACP2 ADCY3 ADRB1 ADRB2 AGT ATG7 ATP2B1 C4orf22 CACNB2 CAPZA1 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CWF19L2 DCAF16 DCBLD1 FAM108C1 FAM57B FCF1P2 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 KLF16 LFNG LSP1 MGRN1 MPI MSRA MYO9B NEIL2 NOC3L NRBF2 NSUN6 NT5C2 OPRL1 PHIP PIGV PRKD3 RGS19 RHOC RNASEH2C RP11-538P18.2 RP11-588K22.2 RP5-1115A15.1 RPP25 SENP3 SH2B3 SLC2A4 SLC4A7 SLC5A11 SOX6 STAG3L2 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TNNT3 UBE2Z UBL7 ULK3 ZBTB46 ZNF318 ZNF831 ZNRF3
Diastolic blood pressure, automated reading	9.33	79	50	111.1	-0.97	1.5e-54	AC006111.1 AC091133.1 ACE ACP2 ADAM1A ADCY3 ADRB1 AGT ATP2B1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CEP41 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTD-3032J10.3 CWF19L2 CYB5D1 DCAF16 FAM108C1 FCF1P2 FES FURIN GMEB2 HEXIM1 HOXA10 LFNG LSP1 MAP2K5 MPI MSRA MYO9B NDUFAF6 NEIL2 NELFCD NOC3L NRBF2 NSUN6 NT5C2 P4HA2-AS1 PDE1A PHIP PIGV RGS19 RHOC RNASEH2C RP11-463M16.4 RP11-538P18.2 RP5-1115A15.1 RPP25 RYK SENP3 SH2B3 SLC2A4 SLC5A11 SNF8 STAG3L2 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TMEM26 UBE2Z UBL7 ULK3 VKORC1 ZC3HC1 ZNF652 ZNF831
Medication for cholesterol, blood pressure or diabetes	8.25	32	14	31.1	0.99	2.5e-31	ACE ATP2B1 C1GALT1 C4orf22 CHP1 CISD2 CLCN6 CSK CTD-3032J10.3 FAM108C1 FCF1P2 FES FURIN LFNG OPRL1 PDXK PLCB1 RGS19 RHOC RP11-588K22.2 SENP1 SH2B3 SIK2 SLC4A7 TCEA2 TCF21 TMEM133 TSPY26P YEATS4 ZBTB46 ZNF652 ZNF831
Medication: Bendroflumethiazide	7.77	35	11	24.4	-0.96	1.9e-22	ACP2 ADCY3 ADRB1 AGT ATP2B1 CACNB2 CAPZA1 CHMP1A CLCN6 CSK FAM108C1 FAM57B FES HOXA10 LSP1 MGRN1 MSRA MYO9B NEIL2 NRBF2 NTN5 P4HA2-AS1 PIGV PLCB1 RHOC RP11-463M16.4 SENP3 SH2B3 SLC4A7 TCF21 TEX15 TMEM133 USP37 VKORC1 ZNF831
Medication for cholesterol	6.99	24	8	17.8	0.96	9.0e-15	ACE ATG7 C4orf22 CAPZA1 CISD2 CMIP FES HOXA10 LSP1 MGRN1 NTN5 OPRL1 PIGV PLCB1 PRKD3 RGS19 RHOC SENP1 SH2B3 TCEA2 TMEM133 ZBTB46 ZNF831 ZNRF3
High blood pressure (mother)	6.11	14	4	8.9	-0.97	6.2e-09	AGT CLCN6 FES FLJ12825 FURIN HOXA10 LSP1 NT5C2 PIGV SENP1 SLC4A7 SNF8 UBE2Z ZNF831
Medication: Amlodipine	6.07	15	7	15.6	-0.95	1.6e-08	CAPZA1 CLCN6 FAM108C1 FES KDM2B LSP1 RHOC RNF34 RP11-617D20.1 SENP1 SENP3 TMEM133 TMEM26 TNNT3 ZNF318
Medication: Atenolol	5.46	6	2	4.4	-0.99	2.6e-05	FES FURIN PRKD3 RHOC SH2B3 TMEM133
Medication: Ramipril	5.42	9	2	4.4	-0.98	1.1e-06	ADAM1A CISD2 CMIP CSK FES GOPC LSP1 TMEM133 ZC3HC1
Number of self-reported non-cancer illnesses	5.31	18	6	13.3	-0.98	1.2e-14	C14orf153 CISD2 CLCN6 CYB5D1 GMEB2 KDM2B MYO9B NTN5 OPRL1 RGS19 RP5-930J4.4 SH2B3 STAG3L2 TCEA2 ZNF318 ZNF652 ZNF831 ZNRF3
High blood pressure (siblings)	4.87	9	3	6.7	-0.97	5.0e-06	ACP2 C14orf153 CLCN6 FES NRBF2 RHOC SH2B3 TMEM133 VKORC1
Medication: Aspirin	4.77	5	1	2.2	-0.98	7.5e-04	DCBLD1 FES OPRL1 RP11-463M16.4 SIK2
Number of treatments/medications taken	4.71	17	7	15.6	-0.95	1.1e-09	AC091133.1 ACE ADAM1A CHP1 CISD2 DCAF16 FAM108C1 FES P4HA2-AS1 RP11-617D20.1 SH2B3 STAG3L2 TMEM133 YEATS4 ZNF652 ZNF831 ZNRF3
Medication: Lisinopril	4.67	6	0	0.0	-0.98	8.7e-05	ACP2 CSK FCF1P2 LSP1 NRBF2 ZNF831
Medication: Aspirin	4.60	9	1	2.2	-0.97	3.8e-06	AC091133.1 DCBLD1 FES GOPC OPRL1 RGS19 RP11-463M16.4 SIK2 TCEA2
Illnesses of father: High blood pressure	4.47	6	1	2.2	-0.99	4.2e-05	ACE ACP2 C4orf22 CHMP1A FES PLCB1
Blood Eosinophil Count	4.36	21	16	35.6	-0.63	9.8e-04	ADAM1A ADRB2 C14orf153 CERS5 FAM57B FBF1 NDUFAF6 P4HA2-AS1 PDXK PIGV RP11-617D20.1 RP5-1115A15.1 SH2B3 SIK2 SNF8 TCHP TSPY26P VKORC1 ZC3HC1 ZNF652 ZNF831
Illnesses of mother	4.35	3	1	2.2	0.97	2.9e-02	FES SNF8 UBE2Z
Medication: Simvastatin	4.33	9	4	8.9	-0.95	2.4e-05	FES NTN5 OPRL1 PIGV RGS19 RNASEH2C TCEA2 YEATS4 ZNF831
Medication: Cholesterol lowering	4.26	12	4	8.9	-0.96	2.0e-07	CHP1 CLCN6 FES NTN5 OPRL1 PIGV RGS19 RNASEH2C TCEA2 TMEM133 YEATS4 ZNF831
Illnesses of siblings	4.20	8	1	2.2	0.96	4.5e-05	ADAM1A CLCN6 FES NRBF2 SH2B3 SLC5A11 TMEM133 VKORC1
Angina	3.85	9	4	8.9	-0.97	7.6e-08	C14orf153 FES FURIN OPRL1 RGS19 RP11-463M16.4 TCEA2 TCF21 ZNF652
Angina (self-reported)	3.76	8	2	4.4	-0.96	5.5e-07	C14orf153 FES FURIN OPRL1 RGS19 TCEA2 TCF21 ZNF652
Heart attack	3.47	4	1	2.2	-0.94	5.5e-03	FES TCF21 ZC3HC1 ZNF652
Heart attack/myocardial infarction (self-reported)	3.46	5	1	2.2	-0.95	2.7e-04	FES SH2B3 TCF21 ZC3HC1 ZNF652
High cholesterol (Self-reported)	3.38	10	6	13.3	-0.91	3.1e-04	CLCN6 DCAF16 FBF1 NTN5 OPRL1 PIGV RGS19 TCEA2 TMEM133 VKORC1
Cholesterol lowering medication	3.28	8	3	6.7	-0.98	2.7e-05	DCAF16 NTN5 OPRL1 PIGV RGS19 RNF34 TCEA2 VKORC1
Birth weight of first child	3.10	10	4	8.9	0.98	1.0e-08	CLCN6 COX5A CSK DCAF16 FES FURIN GTF2B OPRL1 RPP25 SH2B3
Illnesses of father: None of the above (group 1)	2.93	2	1	2.2	0.00	1.0e+00	FES SH2B3
Blood Platelet Count	2.84	44	31	68.9	0.01	9.2e-01	AC091133.1 ADAM1A C20orf160 CAPZA1 CERS5 CLCN6 COX5A CSK CWF19L2 DCAF16 FBF1 GMEB2 GTF2B HEXIM1 LFNG MGRN1 MPI MYO9B NELFCD NRBF2 NTN5 P4HA2-AS1 PCCB PHIP PIGV RHOC RNASEH2C RP11-463M16.4 RP11-617D20.1 RPP25 SENP1 SH2B3 SIK2 SLC4A7 SNF8 SNX16 SWAP70 TH1L TMEM26 TNNT3 UBL7 USP37 ZC3HC1 ZNF318
Father's age at death	2.71	4	2	4.4	0.94	5.8e-02	FES MPI P4HA2-AS1 SH2B3
Birth weight	2.70	12	9	20.0	0.57	4.3e-02	ADAM1A ADCY3 ADRB1 DCAF16 FES FURIN NTN5 SH2B3 SIK2 SLC2A4 TNNT3 ZNRF3
Illnesses of father: Heart disease	2.70	2	1	2.2	0.00	1.0e+00	FES TCF21
Overall health rating	2.69	11	5	11.1	-0.98	3.5e-09	AC091133.1 C1GALT1 HEXIM1 MSRA RNASEH2C SLC5A11 STAG3L2 TEX15 TSPY26P VKORC1 ZNF652
Coronary Artery Disease (CAD)	2.67	6	2	4.4	-0.96	2.7e-03	DBR1 NT5C2 RP11-463M16.4 SH2B3 SNF8 TCF21
Taking other prescription medications	2.59	6	2	4.4	-0.99	4.2e-07	ADAM1A CHP1 CISD2 SH2B3 STAG3L2 ZNF652
Impedance of whole body	2.58	33	22	48.9	0.37	2.8e-02	ATG7 CEP41 CERS5 CISD2 CTB-31O20.6 CTD-3032J10.3 FAM108C1 FAM57B FLJ12825 HEXIM1 HSD17B12 KLF16 LSP1 MAP2K5 MARCH2 MSRA MYO9B NEIL2 NOC3L NT5C2 PDE1A PRKD3 RP11-463M16.4 RP4-758J18.10 RYK SENP1 SENP3 SLC4A7 STAG3L2 SWAP70 USP37 VKORC1 ZNF652
Impedance of leg (right)	2.56	34	19	42.2	0.09	6.0e-01	AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 CTD-3032J10.3 FAM108C1 FAM57B FES FLJ12825 FURIN HEXIM1 HSD17B12 KLF16 MAP2K5 MSRA MYO9B NEIL2 NOC3L NT5C2 PRKD3 RP11-463M16.4 RP4-758J18.10 RYK SENP1 SENP3 SNAP47 STAG3L2 SWAP70 TMEM133 USP37 VKORC1 WDR66 ZNF652
Impedance of leg (left)	2.49	30	18	40.0	0.14	4.4e-01	AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 CTD-3032J10.3 FAM108C1 FAM57B FES FLJ12825 FURIN HEXIM1 HSD17B12 KLF16 MAP2K5 MSRA MYO9B NEIL2 NOC3L NT5C2 PRKD3 RP11-463M16.4 RP4-758J18.10 SNAP47 STAG3L2 SWAP70 TMEM133 USP37 VKORC1 ZNF652
Body mass index (BMI)	2.42	23	15	33.3	-0.82	1.7e-06	AC091133.1 C14orf153 CEP41 COX5A CTB-31O20.6 FAM108C1 FAM57B HSD17B12 KDM2B KLF16 MAP2K5 MSRA NEIL2 NRBF2 RP5-1115A15.1 RPP25 SLC5A11 SNF8 STAG3L2 TDRD1 TEX15 USP37 VKORC1
Waist circumference	2.42	24	12	26.7	-0.66	4.0e-04	ADCY3 CMIP COX5A CTB-31O20.6 EFR3B FAM108C1 FAM57B HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 MPI NRBF2 PCCB PHIP RP11-810M2.2 RPP25 SLC5A11 STAG3L2 TDRD1 TEX15 UBL7 VKORC1
Allergy	2.41	9	5	11.1	0.11	7.4e-01	ADAM1A CHP1 FES GMEB2 HEXIM1 P4HA2-AS1 RP5-1115A15.1 SIK2 ZNF652
Impedance of arm (right)	2.37	31	13	28.9	0.45	7.6e-03	ARID3B CEP41 CERS5 CISD2 CMIP CTB-31O20.6 CTD-3032J10.3 FAM57B FLJ12825 HEXIM1 HOXA10 HSD17B12 KLF16 LSP1 MAP2K5 MARCH2 MSRA MYO9B NEIL2 NOC3L NRBF2 PDE1A RP11-463M16.4 RYK SENP1 SENP3 SLC4A7 SNX16 TSPY26P VKORC1 ZNF652
Impedance of arm (left)	2.37	30	16	35.6	0.37	3.2e-02	ARID3B CERS5 CISD2 CMIP CTD-3032J10.3 FAM108C1 FAM57B FLJ12825 HEXIM1 HOXA10 HSD17B12 LSP1 MAP2K5 MARCH2 MSRA MYO9B NEIL2 NOC3L NRBF2 PDE1A PRKD3 RP11-463M16.4 RYK SENP1 SENP3 SH2B3 SLC4A7 TSPY26P VKORC1 ZNF652
Leg fat percentage (left)	2.36	22	10	22.2	-0.81	5.8e-06	C14orf153 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B GTF2B HSD17B12 KDM2B MAP2K5 MOBP MSRA NOC3L PKP4 RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TEX15 VKORC1
Leg fat percentage (right)	2.33	22	11	24.4	-0.81	5.2e-06	C14orf153 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B GTF2B HSD17B12 KDM2B MAP2K5 MOBP MSRA NOC3L PKP4 RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TEX15 VKORC1
BMI	2.32	35	23	51.1	-0.61	1.0e-04	AC006111.1 AC091133.1 C14orf153 C20orf160 C4orf22 CEP41 CHP1 CISD2 CLCN6 COX5A CTB-31O20.6 FAM108C1 FAM57B HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 NRBF2 NT5C2 PCCB RNF34 RP11-463M16.4 RP11-538P18.2 RP4-758J18.10 RP5-1115A15.1 RPP25 SLC5A11 SNF8 STAG3L2 TDRD1 TEX15 TSPY26P USP37 VKORC1
Hayfever, allergic rhinitis or eczema	2.27	7	5	11.1	-0.25	5.2e-01	ADAM1A CHP1 MPI P4HA2-AS1 RP5-1115A15.1 SIK2 ZNF652
Arm fat percentage (right)	2.27	26	15	33.3	-0.77	3.8e-06	AC091133.1 C14orf153 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KDM2B KLF16 MAP2K5 MSRA RNF34 RP11-810M2.2 RP5-1115A15.1 SENP3 SLC2A4 SLC5A11 SNF8 STAG3L2 TDRD1 TEX15 VKORC1
Allergy or Eczema	2.26	11	6	13.3	-0.20	5.0e-01	ADAM1A CHP1 GMEB2 HEXIM1 MPI NRBF2 P4HA2-AS1 RNF34 RP5-1115A15.1 SIK2 ZNF652
Body fat percentage	2.23	26	11	24.4	-0.62	6.6e-04	AC091133.1 C14orf153 CHP1 COX5A CTB-31O20.6 DBR1 DCAF16 FAM108C1 FAM57B FLJ12825 HOXA10 HSD17B12 KDM2B MAP2K5 MSRA MYO9B NOC3L RNF34 RP11-810M2.2 RP5-1115A15.1 RPP25 SENP3 SLC5A11 STAG3L2 TEX15 VKORC1
Arm fat percentage (left)	2.23	25	15	33.3	-0.71	6.6e-05	AC091133.1 C14orf153 CHP1 COX5A CTB-31O20.6 DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KDM2B KLF16 MAP2K5 MSRA RNF34 RP5-1115A15.1 RPP25 SENP3 SLC2A4 SLC5A11 SNF8 STAG3L2 TEX15 VKORC1
Leg fat mass (left)	2.23	21	12	26.7	-0.81	9.2e-06	AC091133.1 ADCY3 COX5A CTB-31O20.6 FAM108C1 FAM57B HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 MSRA RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TDRD1 TEX15 TSPY26P VKORC1
Blood White Count	2.21	30	18	40.0	-0.58	4.4e-04	ADAM1A ADRB2 C10orf118 C14orf153 CERS5 CMIP CYB5D1 DCAF16 EFR3B FES FLJ12825 FURIN GTF2B KB-1107E3.1 MGRN1 MOBP NRBF2 NT5C2 P4HA2-AS1 PCCB PLCB1 RP11-617D20.1 RP5-1115A15.1 SH2B3 SLC5A11 TEX15 TMEM133 UBE2E3 VKORC1 ZNF652
Breast Cancer	2.20	8	2	4.4	-0.50	1.5e-01	CSK FES FURIN LSP1 RP11-1055B8.4 SIK2 SLC4A7 UBL7
Leg fat mass (right)	2.20	20	10	22.2	-0.88	2.4e-07	AC091133.1 ADCY3 CTB-31O20.6 FAM108C1 FAM57B HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 MOBP MSRA RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TEX15 TSPY26P VKORC1
Asthma	2.19	4	4	8.9	-0.69	8.4e-02	P4HA2-AS1 RP5-1115A15.1 SIK2 ZNF652
Arm fat mass (right)	2.19	22	10	22.2	-0.74	7.8e-05	AC091133.1 ADCY3 COX5A CTB-31O20.6 EFR3B FAM108C1 FAM57B HOXA10 HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 MSRA RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TDRD1 TEX15 VKORC1
Asthma (self-reported)	2.19	5	4	8.9	-0.49	2.2e-01	FBF1 P4HA2-AS1 RP5-1115A15.1 SIK2 ZNF652
Bipolar Disorder or Schizophrenia	2.18	9	4	8.9	0.33	3.5e-01	C14orf153 CERS5 CHMP1A FAM57B FES FURIN MSRA NT5C2 TBC1D19
Height	2.17	51	44	97.8	0.39	3.6e-03	AC006111.1 AC091133.1 ACE ACP2 ADCY3 ADRB1 ARID3B C14orf153 CAPZA1 CERS5 CHP1 DBR1 DCAF16 EFR3B FAM57B FES FURIN GOPC GTF2B HEXIM1 LSP1 MARCH2 MGRN1 NTN5 P4HA2-AS1 PDE1A PIGV RHOC RP11-1055B8.4 RP11-463M16.4 RP11-538P18.2 RP11-617D20.1 RP11-810M2.2 RP5-1115A15.1 RP5-930J4.4 RP5-994D16.9 RYK SENP3 SH2B3 SLC4A7 SLC5A11 SNAP47 SNF8 TMEM133 UBE2Z USP37 WDR66 YEATS4 ZNF318 ZNF652 ZNF831
Diabetes diagnosed by doctor	2.17	2	1	2.2	0.00	1.0e+00	DBR1 ZBTB46
Type 2 Diabetes (T2D) (2018)	2.15	7	0	0.0	-0.98	1.7e-04	ACE DBR1 FAM57B NDUFAF6 SH2B3 SNF8 ZBTB46
Arm fat mass (left)	2.15	21	10	22.2	-0.74	1.3e-04	AC091133.1 ADCY3 COX5A CTB-31O20.6 EFR3B FAM108C1 FAM57B HOXA10 HSD17B12 KDM2B KLF16 MAP2K5 MSRA RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TDRD1 TEX15 VKORC1
Hypothyroidism (self reported)	2.11	4	2	4.4	-0.73	2.7e-01	ADAM1A NTN5 RP5-1115A15.1 SH2B3
Trunk fat percentage	2.11	24	9	20.0	-0.72	6.9e-05	AC091133.1 ADCY3 CHP1 CTB-31O20.6 CTD-3032J10.3 DBR1 FAM108C1 FAM57B FLJ12825 HOXA10 HSD17B12 KDM2B MAP2K5 MSRA MYO9B NOC3L RNF34 RP11-810M2.2 RP5-1115A15.1 SENP3 SLC5A11 STAG3L2 TEX15 VKORC1
Whole body fat mass	2.11	22	13	28.9	-0.68	4.8e-04	AC091133.1 ADCY3 COX5A CTB-31O20.6 DBR1 FAM108C1 FAM57B HOXA10 HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 MSRA RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TDRD1 TEX15 VKORC1
Medication: Atorvastatin	2.11	1	0	0.0	0.00	1.0e+00	VKORC1
Comparative body size at age 10	2.10	10	5	11.1	-0.42	1.6e-01	ATG7 CERS5 EFR3B FAM57B FCF1P2 MAP2K5 MSRA NTN5 VKORC1 ZNF652
Long-standing illness, disability or infirmity	2.10	3	0	0.0	-0.47	5.3e-01	CHP1 STAG3L2 ZNF652
Schizophrenia (2014)	2.09	8	4	8.9	0.35	3.5e-01	CERS5 FAM57B FES FURIN MSRA NT5C2 PCCB RP5-1115A15.1
Respiratory disease	2.09	7	3	6.7	-0.70	2.5e-02	CHP1 GMEB2 HEXIM1 P4HA2-AS1 RP5-1115A15.1 SIK2 ZNF652
Standing height	2.09	43	29	64.4	0.36	1.4e-02	AC006111.1 AC091133.1 ACP2 ADCY3 ADRB1 C10orf118 C14orf153 CAPZA1 CERS5 CHP1 DCAF16 EFR3B FAM57B GOPC GTF2B HEXIM1 LSP1 MARCH2 MGRN1 MSRA P4HA2-AS1 PDE1A PIGV RHOC RP11-1055B8.4 RP11-463M16.4 RP11-538P18.2 RP11-617D20.1 RP11-810M2.2 RP5-1115A15.1 RP5-930J4.4 RYK SH2B3 SLC4A7 SLC5A11 SNAP47 SNF8 UBE2Z USP37 WDR66 ZNF318 ZNF652 ZNF831
Arm predicted mass (left)	2.04	21	12	26.7	-0.26	2.5e-01	ADCY3 C10orf118 CMIP DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA NEIL2 P4HA2-AS1 PDE1A SENP3 SH2B3 SLC5A11 VKORC1 WDR66
Schizophrenia (2018)	2.03	7	4	8.9	0.51	1.9e-01	FAM57B FES FURIN MSRA NT5C2 PCCB TBC1D19
Trunk fat mass	2.03	20	8	17.8	-0.72	3.0e-04	ADCY3 CTB-31O20.6 DBR1 FAM108C1 FAM57B HOXA10 HSD17B12 KB-1107E3.1 KDM2B KLF16 MAP2K5 MSRA RP11-810M2.2 RP5-1115A15.1 RPP25 SLC5A11 STAG3L2 TDRD1 TEX15 VKORC1
Arm predicted mass (right)	2.03	23	13	28.9	-0.24	2.6e-01	ADCY3 C10orf118 CMIP DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA MYO9B NEIL2 P4HA2-AS1 PDE1A SENP3 SH2B3 SLC5A11 TSPY26P VKORC1 WDR66
Trunk fat-free mass	2.02	23	13	28.9	0.03	9.1e-01	ADCY3 C10orf118 C14orf153 CTD-3032J10.3 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MARCH2 MYO9B P4HA2-AS1 PDE1A SENP3 SH2B3 SLC4A7 SLC5A11 SNF8 TMEM133 UBE2Z WDR66
Trunk predicted mass	2.02	22	12	26.7	0.01	9.5e-01	ADCY3 C10orf118 C14orf153 CTD-3032J10.3 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MARCH2 MYO9B P4HA2-AS1 PDE1A SENP3 SH2B3 SLC4A7 SLC5A11 SNF8 UBE2Z WDR66
Weight	2.01	22	15	33.3	-0.51	1.6e-02	ADCY3 C10orf118 CTB-31O20.6 DCAF16 EFR3B FAM108C1 FAM57B HSD17B12 KB-1107E3.1 KLF16 MAP2K5 MSRA NEIL2 P4HA2-AS1 RP11-810M2.2 RPP25 SH2B3 SLC5A11 STAG3L2 TDRD1 VKORC1 WDR66
Arm fat-free mass (right)	2.01	21	13	28.9	-0.20	3.8e-01	ADCY3 C10orf118 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA MYO9B NEIL2 P4HA2-AS1 PDE1A SENP3 SH2B3 SLC5A11 VKORC1 WDR66
Whole body water mass	2.01	24	14	31.1	-0.20	3.6e-01	ADCY3 C10orf118 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA MYO9B NEIL2 NT5C2 P4HA2-AS1 PDE1A SENP3 SH2B3 SLC4A7 SLC5A11 UBE2Z VKORC1 WDR66
Arm fat-free mass (left)	2.01	23	13	28.9	-0.28	1.9e-01	ADCY3 C10orf118 CMIP DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA NEIL2 P4HA2-AS1 PDE1A RP11-810M2.2 SENP3 SH2B3 SLC5A11 TSPY26P VKORC1 WDR66
Whole body fat-free mass	2.00	23	14	31.1	-0.20	3.5e-01	ADCY3 C10orf118 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA MYO9B NEIL2 NT5C2 P4HA2-AS1 PDE1A SENP3 SH2B3 SLC4A7 SLC5A11 VKORC1 WDR66
Heel T-Score	1.98	31	21	46.7	0.14	4.4e-01	ACP2 ATG7 C14orf153 C20orf160 CAPZA1 CMIP CYB5D1 DCAF16 FAM57B GTF2B HEXIM1 LFNG MARCH2 NELFCD NT5C2 PDE1A RHOC RNASEH2C RP11-810M2.2 RP5-1115A15.1 SENP3 SLC5A11 SNAP47 SOX6 STAG3L2 TH1L TMEM133 UBE2E3 VKORC1 ZNF318 ZNRF3
Hypothyroidism/myxoedema (self-reported)	1.98	4	3	6.7	-0.19	8.1e-01	ADAM1A MSRA RP5-1115A15.1 SH2B3
Basal metabolic rate	1.98	21	15	33.3	-0.27	2.4e-01	ADCY3 C10orf118 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KLF16 MAP2K5 MARCH2 MSRA NEIL2 NT5C2 P4HA2-AS1 PDE1A SH2B3 SLC5A11 TDRD1 VKORC1 WDR66
Medication for pain relief, constipation, heartburn	1.95	4	1	2.2	0.98	1.7e-02	ACE C20orf160 FAM108C1 YEATS4
Medication: Levothyroxine sodium	1.94	3	2	4.4	0.00	1.0e+00	ADAM1A MSRA SH2B3
Diabetes (self-reported)	1.94	2	0	0.0	0.00	1.0e+00	STAG3L2 ZBTB46
Leg fat-free mass (right)	1.94	22	15	33.3	-0.04	8.7e-01	C10orf118 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KLF16 MAP2K5 MSRA MYO9B NEIL2 NT5C2 P4HA2-AS1 PDE1A SH2B3 SLC5A11 TDRD1 TMEM133 VKORC1 WDR66
Leg predicted mass (right)	1.94	21	15	33.3	-0.07	7.8e-01	C10orf118 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KLF16 MAP2K5 MSRA MYO9B NEIL2 NT5C2 P4HA2-AS1 PDE1A SH2B3 SLC5A11 TDRD1 VKORC1 WDR66
Wheeze or whistling in the chest in last year	1.93	4	0	0.0	0.94	6.4e-02	GMEB2 SIK2 VKORC1 ZNF652
Blood Red Count	1.92	34	24	53.3	-0.58	1.5e-04	ADAM1A ARID3B C14orf153 C20orf160 C4orf22 CLCN6 COX5A CSK CYB5D1 FAM57B FBF1 GMEB2 GTF2B HEXIM1 MAP2K5 MGRN1 MPI NDUFAF6 NELFCD NT5C2 PDXK RNASEH2C RP11-617D20.1 RP5-930J4.4 RPP25 SENP1 SH2B3 TDRD1 TH1L TSPY26P UBE2E3 UBL7 USP37 VKORC1
Bipolar Disorder (2018)	1.90	1	0	0.0	0.00	1.0e+00	ZC3HC1
Leg fat-free mass (left)	1.89	20	14	31.1	-0.22	3.5e-01	C10orf118 CTB-31O20.6 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KLF16 MAP2K5 MSRA NEIL2 NT5C2 P4HA2-AS1 PDE1A SLC5A11 TDRD1 VKORC1 WDR66
Leg predicted mass (left)	1.89	21	13	28.9	-0.21	3.7e-01	C10orf118 CTB-31O20.6 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KLF16 MAP2K5 MSRA MYO9B NEIL2 NT5C2 P4HA2-AS1 PDE1A SLC5A11 TDRD1 VKORC1 WDR66
Hip circumference	1.88	18	10	22.2	-0.49	3.8e-02	C10orf118 CLCN6 CTB-31O20.6 DCAF16 FAM108C1 FAM57B HSD17B12 KB-1107E3.1 KLF16 MAP2K5 MSRA PHIP RP11-810M2.2 SH2B3 SLC5A11 STAG3L2 VKORC1 WDR66
Waist Hip Ratio (WHR)	1.87	22	11	24.4	-0.62	2.0e-03	ADAM1A ADCY3 CEP41 CMIP CTD-3032J10.3 DBR1 FLJ12825 GTF2B MYO9B NTN5 OPRL1 PCCB RGS19 RNASEH2C RP5-930J4.4 SIK2 SNAP47 SWAP70 TBC1D19 TCEA2 ZNF318 ZNRF3
Heel bone mineral density (BMD) T-score, automated (right)	1.85	9	5	11.1	-0.03	9.5e-01	ACP2 C14orf153 CYB5D1 DCAF16 MSRA NEIL2 RNASEH2C RP5-1115A15.1 ZNRF3
Heart disease (siblings)	1.85	1	0	0.0	0.00	1.0e+00	FES
Forced expiratory volume in 1-second (FEV1)	1.82	11	3	6.7	0.00	1.0e+00	DCAF16 GOPC MSRA NRBF2 RHOC RP11-538P18.2 SNAP47 TMEM133 TSPY26P UBE2E3 VKORC1
Forced vital capacity (FVC)	1.80	10	5	11.1	0.71	2.2e-02	ACP2 CAPZA1 DCAF16 GMEB2 RHOC RP11-538P18.2 SNAP47 SNF8 VKORC1 WDR66
Heel bone mineral density (BMD) T-score, automated (left)	1.79	9	3	6.7	0.04	9.2e-01	ACP2 C14orf153 CMIP CYB5D1 MSRA NEIL2 RNASEH2C RP5-1115A15.1 ZNRF3
Alcohol intake frequency.	1.76	7	4	8.9	-0.68	9.3e-02	ARID3B FAM57B NTN5 STAG3L2 TEX15 VKORC1 ZNF318
Current tobacco smoking	1.75	2	0	0.0	0.00	1.0e+00	MSRA SLC5A11
Pulse wave Arterial Stiffness index	1.75	1	1	2.2	0.00	1.0e+00	ADAM1A
Peak expiratory flow (PEF)	1.75	6	4	8.9	0.71	1.1e-01	C1GALT1 DCAF16 MSRA NTN5 SLC2A4 TCF21
Supplements: Glucosamine	1.74	2	1	2.2	0.00	1.0e+00	CSK NRBF2
Comparative height size at age 10	1.74	19	10	22.2	0.33	1.7e-01	ADCY3 C14orf153 DCAF16 FAM108C1 FAM57B FES GTF2B NTN5 P4HA2-AS1 PIGV RP11-617D20.1 RP11-810M2.2 RP5-1115A15.1 RYK SH2B3 SNAP47 SNF8 UBE2Z WDR66
Sitting height	1.73	25	15	33.3	0.31	1.2e-01	AC091133.1 ADRB1 C10orf118 C14orf153 C20orf160 CERS5 CHP1 DCAF16 FCN3 GOPC GTF2B HEXIM1 MARCH2 NTN5 P4HA2-AS1 RP11-463M16.4 RP11-538P18.2 SLC4A7 SNAP47 SNF8 UBE2Z WDR66 ZNF652 ZNF831 ZNRF3
Forced expiratory volume in 1-second (FEV1), Best measure	1.73	7	4	8.9	0.08	8.7e-01	DCAF16 MSRA NRBF2 RP11-538P18.2 SNAP47 TMEM133 VKORC1
HDL Cholesterol	1.71	4	1	2.2	0.68	3.2e-01	ACP2 ADRB1 PIGV RNASEH2C
Lupus	1.70	1	0	0.0	0.00	1.0e+00	MSRA
Financial difficulties in last 2 years	1.70	1	0	0.0	0.00	1.0e+00	VKORC1
Medication: Metformin	1.69	2	0	0.0	0.00	1.0e+00	CISD2 DBR1
Past tobacco smoking	1.69	3	1	2.2	0.00	1.0e+00	ADAM1A MAP2K5 SH2B3
Medication: Allopurinol	1.69	3	0	0.0	0.00	1.0e+00	CYB5D1 SH2B3 WDR66
Smoking Status	1.68	8	0	0.0	-0.48	1.2e-01	ADAM1A FAM108C1 FES MAP2K5 RP11-463M16.4 RP5-1115A15.1 SLC5A11 ZNF652
Pulse wave peak to peak time	1.68	1	1	2.2	0.00	1.0e+00	ADAM1A
Lung FEV1/FVC ratio	1.67	20	14	31.1	0.42	4.7e-02	ATG7 ATP2B1 C1GALT1 CACNB2 CEP41 CTB-31O20.6 CYB5D1 FLJ12825 GOPC KB-1107E3.1 MARCH2 NRBF2 NTN5 P4HA2-AS1 RP11-810M2.2 RP5-1115A15.1 TCF21 TMEM133 TSPY26P ZNF652
Lung FVC	1.66	19	12	26.7	0.30	2.0e-01	C1GALT1 CHP1 CTD-3032J10.3 DBR1 DCAF16 FLJ12825 GMEB2 HOXA10 HSD17B12 MAP2K5 NRBF2 OPRL1 P4HA2-AS1 RP11-538P18.2 SH2B3 TCEA2 TCF21 VKORC1 ZBTB46
Fasting Glucose	1.65	1	1	2.2	0.00	1.0e+00	ACP2
Hearing difficulty/problems with background noise	1.65	5	1	2.2	0.75	8.6e-02	C14orf153 CSK MPI UBL7 ZNF318
LDL Cholesterol	1.64	3	0	0.0	0.00	1.0e+00	NTN5 PIGV SH2B3
Triglycerides	1.64	4	0	0.0	-0.02	9.8e-01	MSRA NEIL2 NRBF2 VKORC1
Hand grip strength (right)	1.64	7	4	8.9	-0.09	8.5e-01	CAPZA1 DCAF16 HEXIM1 P4HA2-AS1 RHOC SLC5A11 SNAP47
Forced vital capacity (FVC), Best measure	1.64	7	3	6.7	0.69	8.6e-02	ACP2 DCAF16 GMEB2 RHOC RP11-538P18.2 SNAP47 VKORC1
Smoking status: Current	1.64	1	0	0.0	0.00	1.0e+00	MSRA
Worrier / anxious feelings	1.63	3	1	2.2	0.00	1.0e+00	MSRA NEIL2 PCCB
Chest pain or discomfort	1.63	1	0	0.0	0.00	1.0e+00	KB-1107E3.1
Age when periods started (menarche)	1.62	7	4	8.9	0.16	7.3e-01	CTB-31O20.6 FAM57B HSD17B12 KLF16 MAP2K5 NTN5 STAG3L2
Hair/balding pattern: Pattern 4	1.62	4	2	4.4	-0.74	2.6e-01	C4orf22 CERS5 HEXIM1 RP5-1115A15.1
Forced expiratory volume in 1-second (FEV1), predicted	1.62	4	2	4.4	0.91	8.9e-02	DCAF16 HEXIM1 MGRN1 P4HA2-AS1
Body Mass Index (BMI) (2010)	1.61	1	1	2.2	0.00	1.0e+00	MAP2K5
Mouth/teeth dental problems	1.61	2	0	0.0	0.00	1.0e+00	C14orf153 NTN5
Osteoarthritis (self-reported)	1.61	2	0	0.0	0.00	1.0e+00	COX5A RPP25
Gout (self-reported)	1.60	1	0	0.0	0.00	1.0e+00	SH2B3
Hand grip strength (left)	1.59	8	3	6.7	0.22	6.0e-01	DCAF16 FAM57B FES HEXIM1 MGRN1 P4HA2-AS1 SLC5A11 SNAP47
Average weekly red wine intake	1.59	1	0	0.0	0.00	1.0e+00	MPI
Prostate Cancer	1.56	1	0	0.0	0.00	1.0e+00	TNNT3
Sensitivity / hurt feelings	1.56	5	2	4.4	0.54	2.6e-01	AC091133.1 FES FURIN MSRA SNF8
Frequency of tiredness / lethargy in last 2 weeks	1.53	3	0	0.0	0.00	1.0e+00	AC091133.1 RP5-1115A15.1 SNF8
Mineral and other dietary supplements	1.53	1	0	0.0	0.00	1.0e+00	NRBF2
Knee pain experienced in last month	1.52	1	0	0.0	0.00	1.0e+00	ARID3B
Ever smoked	1.52	2	0	0.0	0.00	1.0e+00	MAP2K5 SH2B3
Medication: Seretide 50 evohaler	1.51	2	0	0.0	0.00	1.0e+00	P4HA2-AS1 ZNF652
Medication: Gliclazide	1.50	1	0	0.0	0.00	1.0e+00	DBR1
Neuroticism (2016)	1.49	2	1	2.2	0.00	1.0e+00	MSRA NEIL2
Hair/balding pattern: Pattern 3	1.49	2	1	2.2	0.00	1.0e+00	C4orf22 HEXIM1
Medication: Ventolin 100micrograms inhaler	1.49	1	0	0.0	0.00	1.0e+00	ZNF652
Number of full sisters	1.49	1	0	0.0	0.00	1.0e+00	NRBF2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.49	4	1	2.2	0.22	7.8e-01	MSRA NRBF2 RP11-538P18.2 VKORC1
Tanning	1.47	5	3	6.7	0.30	6.2e-01	CHMP1A NRBF2 SH2B3 TSPY26P UBL7
Alcohol usually taken with meals	1.47	1	0	0.0	0.00	1.0e+00	FES
Nervous feelings	1.47	2	2	4.4	0.00	1.0e+00	MSRA PCCB
Diabetes (father)	1.46	2	0	0.0	0.00	1.0e+00	AC091133.1 SNF8
Fed-up feelings	1.46	5	2	4.4	0.33	5.9e-01	MSRA SH2B3 SLC2A4 SLC5A11 TEX15
Alzheimer’s Disease (including proxy)	1.45	3	1	2.2	0.00	1.0e+00	ACE PRKD3 VKORC1
Irritable Bowel Disease (IBD)	1.45	5	1	2.2	0.43	4.6e-01	GMEB2 OPRL1 P4HA2-AS1 RGS19 STAG3L2
Qualifications: None of the above	1.45	3	1	2.2	0.00	1.0e+00	PHIP SLC5A11 UBE2Z
Number of incorrect matches in round	1.44	4	2	4.4	0.93	6.5e-02	FAM57B FES FURIN VKORC1
Worry too long after embarrassment	1.44	2	2	4.4	0.00	1.0e+00	MSRA PCCB
Maternal smoking around birth	1.43	3	1	2.2	0.00	1.0e+00	C14orf153 C20orf160 SLC5A11
Frequency of depressed mood in last 2 weeks	1.42	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.42	1	0	0.0	0.00	1.0e+00	RP5-930J4.4
Neuroticism score	1.42	4	2	4.4	1.00	1.4e-03	MSRA NEIL2 PCCB RP5-1115A15.1
Age at first live birth	1.41	1	0	0.0	0.00	1.0e+00	DCAF16
Had major operations	1.41	1	0	0.0	0.00	1.0e+00	ZNF652
Crohns Disease (2017)	1.40	3	2	4.4	0.00	1.0e+00	NTN5 P4HA2-AS1 STAG3L2
Back pain experienced in last month	1.40	1	0	0.0	0.00	1.0e+00	WDR66
Tense / 'highly strung'	1.39	4	1	2.2	0.55	4.5e-01	MSRA NT5C2 PCCB RP5-1115A15.1
Mean time to correctly identify matches	1.39	2	1	2.2	0.00	1.0e+00	RP11-810M2.2 SH2B3
Smoking status: Previous	1.39	2	0	0.0	0.00	1.0e+00	MAP2K5 SH2B3
Mouth/teeth dental problems: Dentures	1.37	3	1	2.2	0.00	1.0e+00	MSRA NTN5 RP11-1055B8.4
Alcohol intake versus 10 years previously	1.36	3	0	0.0	0.00	1.0e+00	FAM57B NTN5 PDXK
Pulse rate, automated reading	1.36	6	1	2.2	0.43	4.0e-01	ACP2 C4orf22 SIK2 STAG3L2 TCF21 TMEM26
Qualifications: A levels/AS levels or equivalent	1.35	3	0	0.0	0.00	1.0e+00	DCAF16 MSRA SLC5A11
Ulcerative Colitis (UC)	1.34	2	1	2.2	0.00	1.0e+00	OPRL1 RGS19
Reaction Time	1.33	1	1	2.2	0.00	1.0e+00	SH2B3
Depression (Nagel 2018)	1.32	2	0	0.0	0.00	1.0e+00	PCCB RP5-1115A15.1
Loneliness, isolation	1.31	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Risk taking	1.30	2	0	0.0	0.00	1.0e+00	MSRA PCCB
Myopia	1.30	1	0	0.0	0.00	1.0e+00	CAPZA1
Hair/balding pattern: Pattern 2	1.29	1	1	2.2	0.00	1.0e+00	C4orf22
Fluid intelligence score	1.27	2	1	2.2	0.00	1.0e+00	DCAF16 SLC5A11
Mood swings	1.27	3	1	2.2	0.00	1.0e+00	ACP2 MSRA SLC5A11
Worry (Nagel 2018)	1.26	2	1	2.2	0.00	1.0e+00	NT5C2 PCCB
Breastfed as a baby	1.26	1	0	0.0	0.00	1.0e+00	RP4-758J18.10
Pulse wave reflection index	1.25	1	0	0.0	0.00	1.0e+00	FLJ12825
Headache pain in last month	1.25	1	0	0.0	0.00	1.0e+00	MAP2K5
Miserableness	1.25	3	1	2.2	0.00	1.0e+00	ACP2 MSRA RP5-1115A15.1
Unable to work because of sickness or disability	1.25	1	0	0.0	0.00	1.0e+00	SLC5A11
Neck or shoulder pain in last month	1.24	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Major Depression (MDD)	1.23	2	0	0.0	0.00	1.0e+00	FES NT5C2
Rheumatoid Arthritis	1.22	1	0	0.0	0.00	1.0e+00	SH2B3
Townsend deprivation index at recruitment	1.22	2	0	0.0	0.00	1.0e+00	KLF16 MAP2K5
Breast cancer (self-reported)	1.22	1	0	0.0	0.00	1.0e+00	SLC4A7
Eye problems/disorders: Glaucoma	1.22	1	0	0.0	0.00	1.0e+00	TEX15
Neuroticism	1.21	5	1	2.2	0.62	2.6e-01	FURIN MAP2K5 NT5C2 PCCB RP5-1115A15.1
Migraine (self-reported)	1.21	1	0	0.0	0.00	1.0e+00	NT5C2
Suffer from 'nerves'	1.21	2	0	0.0	0.00	1.0e+00	MSRA RP5-1115A15.1
Supplements: Fish oil (including cod liver oil)	1.21	1	0	0.0	0.00	1.0e+00	HEXIM1
Chronotype (morning person)	1.20	3	0	0.0	0.00	1.0e+00	RP11-810M2.2 RP5-1115A15.1 RP5-930J4.4
Hearing difficulty/problems: Yes	1.20	1	1	2.2	0.00	1.0e+00	ZNF318
Qualifications: College or University degree	1.20	7	2	4.4	0.99	1.1e-05	DCAF16 FAM57B GTF2B PKP4 SLC5A11 TEX15 VKORC1
Primary Biliary Cirrhosis	1.19	2	1	2.2	0.00	1.0e+00	CISD2 SH2B3
Relative age voice broke	1.19	1	0	0.0	0.00	1.0e+00	STAG3L2
Ever had bowel cancer screening	1.19	1	0	0.0	0.00	1.0e+00	SIK2
Depressed Affect (Nagel 2018)	1.18	3	2	4.4	0.00	1.0e+00	ACP2 RP5-1115A15.1 SH2B3
Crohns Disease (2012)	1.18	1	1	2.2	0.00	1.0e+00	P4HA2-AS1
Relative age of first facial hair	1.18	3	2	4.4	0.00	1.0e+00	ATG7 C4orf22 HEXIM1
Serious illness, injury or assault of a close relative in last 2 years	1.18	1	0	0.0	0.00	1.0e+00	NTN5
Seen a psychiatrist for nerves, anxiety, tension or depression	1.17	1	0	0.0	0.00	1.0e+00	ADRB1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.17	1	0	0.0	0.00	1.0e+00	KDM2B
Intelligence (Savage-Jansen 2018)	1.16	3	1	2.2	0.00	1.0e+00	DCAF16 GTF2B SLC5A11
Verbal and Numeric Reasoning (VNR)	1.16	3	1	2.2	0.00	1.0e+00	DCAF16 SLC5A11 TEX15
Neuroticism (Nagel 2018)	1.15	4	2	4.4	-0.87	1.3e-01	ACP2 FURIN PCCB RP5-1115A15.1
Irritability	1.15	2	2	4.4	0.00	1.0e+00	MSRA NEIL2
Pulse rate	1.08	1	1	2.2	0.00	1.0e+00	TCF21
Guilty feelings	1.07	2	0	0.0	0.00	1.0e+00	MSRA NEIL2
HbA1C	1.05	1	0	0.0	0.00	1.0e+00	ADAM1A
Depression (self-reported)	1.03	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Hair Pigment	0.97	18	10	22.2	-0.23	3.4e-01	ACP2 ATP2B1 C14orf153 C20orf160 C4orf22 CHMP1A DBR1 FES PIGV RGS19 RNASEH2C RP5-1115A15.1 SH2B3 SNX16 SOX6 TSPY26P ZNF831 ZNRF3
Had menopause	0.97	1	0	0.0	0.00	1.0e+00	CHP1
Average weekly fortified wine intake	0.94	1	0	0.0	0.00	1.0e+00	SLC5A11

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Ovary	10	1.10	3.2
GTEx	Prostate	13	1.56	3.1
GTEx	Stomach	18	1.24	3.1
GTEx	Artery Aorta	35	1.18	3.0
GTEx	Brain Cerebellum	17	0.86	3.0
GTEx	Brain Cortex	7	0.68	3.0
GTEx	Brain Frontal Cortex BA9	12	1.30	3.0
GTEx	Adipose Subcutaneous	27	0.77	2.9
GTEx	Adipose Visceral Omentum	17	0.83	2.9
GTEx	Adrenal Gland	14	0.96	2.9
GTEx	Artery Tibial	36	0.96	2.9
GTEx	Brain Cerebellar Hemisphere	18	1.21	2.9
GTEx	Brain Nucleus accumbens basal ganglia	5	0.58	2.9
GTEx	Esophagus Gastroesophageal Junction	13	0.90	2.9
GTEx	Heart Left Ventricle	15	0.98	2.9
GTEx	Lung	23	0.80	2.9
GTEx	Muscle Skeletal	25	0.87	2.9
GTEx	Pancreas	11	0.67	2.9
GTEx	Pituitary	9	0.81	2.9
GTEx	Skin Not Sun Exposed Suprapubic	25	1.02	2.9
GTEx	Skin Sun Exposed Lower leg	31	0.85	2.9
GTEx	Small Intestine Terminal Ileum	5	1.08	2.9
ROSMAP	Brain Pre-frontal Cortex	43	0.98	2.9
GTEx	Artery Coronary	7	0.59	2.8
GTEx	Brain Caudate basal ganglia	3	0.33	2.8
GTEx	Brain Hippocampus	4	0.76	2.8
GTEx	Breast Mammary Tissue	15	0.76	2.8
GTEx	Breast Mammary Tissue (Male)	14	1.17	2.8
GTEx	Cells EBV-transformed lymphocytes	6	0.42	2.8
GTEx	Cells Transformed fibroblasts	36	0.86	2.8
GTEx	Colon Sigmoid	13	0.89	2.8
GTEx	Colon Transverse	17	0.82	2.8
GTEx	Esophagus Mucosa	33	0.99	2.8
GTEx	Esophagus Muscularis	31	0.96	2.8
GTEx	Heart Atrial Appendage	13	0.82	2.8
GTEx	Spleen	9	0.64	2.8
GTEx	Testis	25	0.79	2.8
GTEx	Thyroid	35	0.88	2.8
GTEx	Uterus	7	1.23	2.8
GTEx	Vagina	5	0.79	2.8
The Cancer Genome Atlas	Colon Adenocarcinoma	20	0.97	2.8
GTEx	Breast Mammary Tissue (Female)	14	0.85	2.7
GTEx	Nerve Tibial	33	0.76	2.7
GTEx	Whole Blood	17	0.85	2.7
NTR	Blood	16	0.67	2.7
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	34	0.83	2.7
The Cancer Genome Atlas	Lung Adenocarcinoma	20	0.68	2.7
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	16	0.96	2.7
The Cancer Genome Atlas	Skin Cutaneous Melanoma	2	0.37	2.7
The Cancer Genome Atlas	Stomach Adenocarcinoma	14	0.83	2.7
GTEx	Brain Hypothalamus	3	0.51	2.6
GTEx	Brain Putamen basal ganglia	4	0.64	2.6
GTEx	Liver	5	0.70	2.6
CommonMind	Brain Pre-frontal Cortex	42	0.78	2.6
The Cancer Genome Atlas	Breast Invasive Carcinoma	34	0.77	2.6
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	7	0.64	2.6
The Cancer Genome Atlas	Glioblastoma Multiforme	4	0.39	2.6
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	19	0.70	2.6
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	14	0.68	2.6
The Cancer Genome Atlas	Brain Lower Grade Glioma	28	0.65	2.6
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	14	0.56	2.6
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	13	0.82	2.6
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	11	0.83	2.6
The Cancer Genome Atlas	Rectum Adenocarcinoma	4	0.58	2.6
The Cancer Genome Atlas	Soft Tissue Sarcoma	5	0.47	2.6
The Cancer Genome Atlas	Testicular Germ Cell Tumors	5	0.39	2.6
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	3	0.59	2.6
METSIM	Adipose	22	0.48	2.5
YFS	Blood	29	0.63	2.5
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	9	0.54	2.5
The Cancer Genome Atlas	Esophageal Carcinoma	1	0.15	2.5
The Cancer Genome Atlas	Thyroid Carcinoma	39	0.76	2.5
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	4	0.36	2.4
The Cancer Genome Atlas	Prostate Adenocarcinoma	24	0.52	2.4