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Traits
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Vascular/heart problems diagnosed by doctor
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chr2:181,042,370-184,084,221
Best TWAS P=3.42e-09 · Best GWAS P=1.42e-09 conditioned to 0.0114
181M
181.5M
182M
182.5M
183M
183.5M
184M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
6
NTR
Blood
UBE2E3
0.02
0.00
bslmm
446
0.00
1.1e-02
5.2
5.9
3.4e-09
0.73
0.06
0.76
TRUE
2
GTEx
Brain Hypothalamus
PDE1A
0.24
-0.01
enet
21
-0.01
7.6e-01
3.0
5.2
2.4e-07
0.00
0.07
0.09
TRUE
5
GTEx
Skin Not Sun Exposed Suprapubic
UBE2E3
0.25
0.06
enet
39
0.12
2.5e-07
5.1
5.6
1.9e-08
0.72
0.08
0.92
FALSE
3
GTEx
Esophagus Muscularis
UBE2E3
0.10
0.09
lasso
3
0.08
2.2e-05
5.2
5.5
4.6e-08
0.89
0.05
0.94
FALSE
1
GTEx
Brain Hippocampus
FTH1P20
0.18
0.02
lasso
6
0.00
4.3e-01
6.0
-5.4
5.5e-08
-0.90
0.04
0.49
FALSE
4
GTEx
Nerve Tibial
UBE2E3
0.09
0.03
lasso
3
0.03
6.4e-03
4.9
5.2
2.2e-07
0.83
0.07
0.86
FALSE