TWAS
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Traits
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Traits
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Vascular/heart problems diagnosed by doctor
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chr3:135,273,949-136,746,974
Best TWAS P=1.55e-07 · Best GWAS P=1.4e-09 conditioned to 0.0017
135.2M
135.4M
135.6M
135.8M
136M
136.2M
136.4M
136.6M
136.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
PCCB
0.1
0.07
lasso
4
0.1
4.2e-13
-3.4
-5.2
1.5e-07
-0.78
0.09
0.91
TRUE