[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr4:17,104,059-18,507,692

Best TWAS P=1.63e-09 · Best GWAS P=7.46e-10 conditioned to 0.00611

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	DCAF16	0.10	0.01	enet	6	0.02	4.7e-02	-5.5	6.0	1.6e-09	-0.69	0.08	0.65	TRUE
6	The Cancer Genome Atlas	Brain Lower Grade Glioma	DCAF16	0.09	0.02	lasso	3	0.04	5.2e-05	4.2	5.9	3.6e-09	-0.55	0.04	0.90	FALSE
3	GTEx	Spleen	DCAF16	0.35	0.02	lasso	5	0.11	8.5e-04	4.0	5.4	6.8e-08	-0.66	0.05	0.55	FALSE
8	The Cancer Genome Atlas	Thyroid Carcinoma	DCAF16	0.07	0.04	blup	31	0.07	4.9e-07	4.1	5.4	6.8e-08	-0.55	0.20	0.67	FALSE
4	ROSMAP	Brain Pre-frontal Cortex	DCAF16	0.04	0.02	bslmm	379	0.01	3.9e-02	-5.4	5.3	9.1e-08	-0.79	0.03	0.89	FALSE
2	GTEx	Breast Mammary Tissue (Male)	DCAF16	0.24	0.03	enet	18	-0.01	4.4e-01	-5.4	5.3	9.3e-08	-0.69	0.04	0.64	FALSE
5	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NCAPG	0.14	0.07	lasso	3	0.07	5.2e-08	-5.4	-5.2	1.8e-07	0.73	0.10	0.90	FALSE
7	The Cancer Genome Atlas	Brain Lower Grade Glioma	NCAPG	0.02	0.03	lasso	1	0.02	9.0e-04	-5.2	-5.2	2.2e-07	0.75	0.03	0.57	FALSE