Best TWAS P=1.63e-09 · Best GWAS P=7.46e-10 conditioned to 0.00611
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | DCAF16 | 0.10 | 0.01 | enet | 6 | 0.02 | 4.7e-02 | -5.5 | 6.0 | 1.6e-09 | -0.69 | 0.08 | 0.65 | TRUE |
| 2 | GTEx | Breast Mammary Tissue (Male) | DCAF16 | 0.24 | 0.03 | enet | 18 | -0.01 | 4.4e-01 | -5.4 | 5.3 | 9.3e-08 | -0.69 | 0.04 | 0.64 | FALSE |
| 3 | GTEx | Spleen | DCAF16 | 0.35 | 0.02 | lasso | 5 | 0.11 | 8.5e-04 | 4.0 | 5.4 | 6.8e-08 | -0.66 | 0.05 | 0.55 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | DCAF16 | 0.04 | 0.02 | bslmm | 379 | 0.01 | 3.9e-02 | -5.4 | 5.3 | 9.1e-08 | -0.79 | 0.03 | 0.89 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | NCAPG | 0.14 | 0.07 | lasso | 3 | 0.07 | 5.2e-08 | -5.4 | -5.2 | 1.8e-07 | 0.73 | 0.10 | 0.90 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DCAF16 | 0.09 | 0.02 | lasso | 3 | 0.04 | 5.2e-05 | 4.2 | 5.9 | 3.6e-09 | -0.55 | 0.04 | 0.90 | FALSE |
| 7 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NCAPG | 0.02 | 0.03 | lasso | 1 | 0.02 | 9.0e-04 | -5.2 | -5.2 | 2.2e-07 | 0.75 | 0.03 | 0.57 | FALSE |
| 8 | The Cancer Genome Atlas | Thyroid Carcinoma | DCAF16 | 0.07 | 0.04 | blup | 31 | 0.07 | 4.9e-07 | 4.1 | 5.4 | 6.8e-08 | -0.55 | 0.20 | 0.67 | FALSE |