Best TWAS P=1.16e-10 · Best GWAS P=1.08e-14 conditioned to 5.06e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TBC1D19 | 0.14 | 0.05 | lasso | 4 | 0.06 | 5.4e-05 | 6.5 | -6.4 | 1.2e-10 | 0.57 | 0.80 | 0.17 | TRUE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | TBC1D19 | 0.04 | 0.01 | enet | 14 | 0.00 | 6.7e-01 | 5.7 | -5.4 | 5.4e-08 | 0.39 | 0.02 | 0.05 | FALSE |
| 3 | The Cancer Genome Atlas | Rectum Adenocarcinoma | TBC1D19 | 0.56 | 0.18 | blup | 24 | 0.17 | 7.0e-05 | -7.5 | 6.0 | 2.7e-09 | -0.81 | 0.00 | 0.86 | TRUE |