[Hub]/) : Traits : Vascular/heart problems diagnosed by doctor : ← →

chr6:78,880,271-80,486,611

Best TWAS P=3.25e-09 · Best GWAS P=1.2e-08 conditioned to 0.311

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
10	GTEx	Esophagus Muscularis	PHIP	0.08	0.04	enet	15	0.02	3.6e-02	-5.7	-5.9	3.3e-09	0.88	0.03	0.93	TRUE
7	GTEx	Brain Nucleus accumbens basal ganglia	IRAK1BP1	0.11	0.08	lasso	10	0.07	6.0e-03	-5.5	5.7	1.4e-08	-0.96	0.04	0.86	FALSE
14	GTEx	Muscle Skeletal	IRAK1BP1	0.10	0.11	lasso	2	0.10	1.3e-09	-5.6	-5.6	1.8e-08	0.98	0.03	0.97	FALSE
4	GTEx	Artery Aorta	IRAK1BP1	0.17	0.15	lasso	1	0.11	1.6e-06	-5.6	-5.6	2.4e-08	0.98	0.03	0.97	FALSE
8	GTEx	Colon Sigmoid	IRAK1BP1	0.19	0.20	lasso	2	0.17	1.0e-06	-5.6	-5.6	2.4e-08	0.98	0.03	0.96	FALSE
17	GTEx	Testis	IRAK1BP1	0.39	0.56	lasso	11	0.58	7.7e-31	-5.6	-5.5	3.1e-08	0.98	0.03	0.97	FALSE
18	GTEx	Thyroid	IRAK1BP1	0.09	0.12	lasso	9	0.11	5.2e-09	-5.5	-5.5	3.1e-08	0.97	0.03	0.97	FALSE
15	GTEx	Ovary	IRAK1BP1	0.13	0.15	lasso	2	0.06	1.2e-02	-5.5	-5.5	3.3e-08	0.98	0.04	0.90	FALSE
12	GTEx	Heart Left Ventricle	IRAK1BP1	0.17	0.20	lasso	5	0.20	8.7e-11	-5.5	-5.5	3.4e-08	0.98	0.03	0.97	FALSE
9	GTEx	Esophagus Muscularis	IRAK1BP1	0.17	0.22	lasso	4	0.22	1.6e-13	-5.6	-5.5	4.0e-08	0.96	0.03	0.97	FALSE
3	GTEx	Adrenal Gland	IRAK1BP1	0.33	0.40	enet	31	0.40	1.5e-15	-5.6	-5.5	4.9e-08	0.95	0.03	0.97	FALSE
6	GTEx	Brain Cerebellar Hemisphere	IRAK1BP1	0.21	0.13	enet	26	0.12	4.4e-04	3.9	-5.4	6.1e-08	0.84	0.04	0.94	FALSE
5	GTEx	Artery Tibial	IRAK1BP1	0.11	0.15	lasso	4	0.16	1.4e-12	-5.6	-5.4	7.1e-08	0.96	0.03	0.97	FALSE
13	GTEx	Lung	IRAK1BP1	0.14	0.18	lasso	5	0.17	3.9e-13	-5.5	-5.4	7.7e-08	0.97	0.04	0.96	FALSE
11	GTEx	Heart Atrial Appendage	IRAK1BP1	0.15	0.14	lasso	2	0.12	4.6e-06	-5.5	-5.2	1.7e-07	0.97	0.03	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	IRAK1BP1	0.17	0.16	enet	20	0.19	2.5e-10	-5.6	-5.2	1.8e-07	0.95	0.03	0.97	FALSE
16	GTEx	Prostate	IRAK1BP1	0.15	0.08	enet	7	0.09	2.4e-03	-5.5	-5.2	2.4e-07	0.91	0.05	0.86	FALSE
1	GTEx	Adipose Subcutaneous	IRAK1BP1	0.12	0.10	lasso	4	0.15	2.7e-12	-5.5	-5.1	2.7e-07	0.89	0.04	0.96	FALSE